Class information for:
Level 2: THIOPURINE METHYLTRANSFERASE//6 MERCAPTOPURINE//THIOPURINE S METHYLTRANSFERASE

Basic class information
ID Publications Average number
of references		 Avg. shr. active
ref. in WoS
3031 2012 33.9 74%


Bar chart of Publication_year

Last years might be incomplete

Classes in level above (level 3)


ID, lev.
above		 Publications Label for level above
399 27709 ULCERATIVE COLITIS//CROHNS DISEASE//INFLAMMATORY BOWEL DISEASE

Classes in level below (level 1)


ID, lev. below Publications Label for level below
3654 1859 THIOPURINE METHYLTRANSFERASE//6 MERCAPTOPURINE//THIOPURINE S METHYLTRANSFERASE
29417 153 ORAL CHEMOTHERAPY//ORAL ANTICANCER AGENTS//ORAL ANTICANCER DRUGS

Terms with highest relevance score


Rank Term Type of term Relevance score
(tfidf)		 Class's shr.
of term's tot.
occurrences		 Shr. of publ.
in class containing
term		 Num. of
publ. in
class
1 THIOPURINE METHYLTRANSFERASE Author keyword 332 90% 7% 144
2 6 MERCAPTOPURINE Author keyword 203 53% 13% 271
3 THIOPURINE S METHYLTRANSFERASE Author keyword 190 89% 4% 87
4 AZATHIOPRINE Author keyword 141 30% 20% 401
5 TPMT Author keyword 126 79% 4% 80
6 6 THIOGUANINE NUCLEOTIDES Author keyword 87 94% 2% 31
7 THIOPURINE Author keyword 50 61% 3% 53
8 THIOPURINES Author keyword 48 48% 4% 73
9 6 THIOGUANINE Author keyword 48 47% 4% 76
10 MERCAPTOPURINE Author keyword 47 54% 3% 61

Web of Science journal categories

Author Key Words


Rank Web of Science journal category Relevance score
(tfidf)		 Class's shr.
of term's tot.
occurrences		 Shr. of publ.
in class containing
term		 Num. of
publ. in
class		 LCSH search Wikipedia search
1 THIOPURINE METHYLTRANSFERASE 332 90% 7% 144 Search THIOPURINE+METHYLTRANSFERASE Search THIOPURINE+METHYLTRANSFERASE
2 6 MERCAPTOPURINE 203 53% 13% 271 Search 6+MERCAPTOPURINE Search 6+MERCAPTOPURINE
3 THIOPURINE S METHYLTRANSFERASE 190 89% 4% 87 Search THIOPURINE+S+METHYLTRANSFERASE Search THIOPURINE+S+METHYLTRANSFERASE
4 AZATHIOPRINE 141 30% 20% 401 Search AZATHIOPRINE Search AZATHIOPRINE
5 TPMT 126 79% 4% 80 Search TPMT Search TPMT
6 6 THIOGUANINE NUCLEOTIDES 87 94% 2% 31 Search 6+THIOGUANINE+NUCLEOTIDES Search 6+THIOGUANINE+NUCLEOTIDES
7 THIOPURINE 50 61% 3% 53 Search THIOPURINE Search THIOPURINE
8 THIOPURINES 48 48% 4% 73 Search THIOPURINES Search THIOPURINES
9 6 THIOGUANINE 48 47% 4% 76 Search 6+THIOGUANINE Search 6+THIOGUANINE
10 MERCAPTOPURINE 47 54% 3% 61 Search MERCAPTOPURINE Search MERCAPTOPURINE

Key Words Plus


Rank Web of Science journal category Relevance score
(tfidf)		 Class's shr.
of term's tot.
occurrences		 Shr. of publ.
in class containing
term		 Num. of
publ. in
class
1 6 MERCAPTOPURINE 296 41% 27% 553
2 MERCAPTOPURINE 260 71% 10% 211
3 S METHYLTRANSFERASE 212 76% 8% 151
4 6 THIOGUANINE NUCLEOTIDE 155 95% 3% 53
5 MERCAPTOPURINE METABOLISM 141 83% 4% 79
6 AZATHIOPRINE THERAPY 135 65% 6% 130
7 ERYTHROCYTE CORRELATION 115 100% 2% 33
8 6 THIOGUANINE 115 57% 7% 135
9 AZATHIOPRINE INDUCED MYELOSUPPRESSION 104 90% 2% 45
10 6 MERCAPTOPURINE THERAPY 97 85% 3% 51

Journals

Reviews


Title Publ. year Cit. Active references % act. ref.
to same field
Review article: the benefits of pharmacogenetics for improving thiopurine therapy in inflammatory bowel disease 2012 47 205 85%
Update 2014: Advances to Optimize 6-Mercaptopurine and Azathioprine to Reduce Toxicity and Improve Efficacy in the Management of IBD 2015 1 78 86%
Getting the best out of thiopurine therapy: thiopurine S-methyltransferase and beyond 2015 1 103 83%
Clinical pharmacology and pharmacogenetics of thiopurines 2008 119 125 81%
Nomenclature for alleles of the thiopurine methyltransferase gene 2013 20 46 91%
Thiopurine-induced myelotoxicity in patients with inflammatory bowel disease: A review 2008 62 124 91%
Adherence enhancing interventions for oral anticancer agents: A systematic review 2014 9 17 59%
Genetic polymorphism of thiopurine methyltransferase and its clinical relevance for childhood acute lymphoblastic leukemia 2000 222 30 100%
Assessment of Thiopurine S-Methyltransferase Activity in Patients Prescribed Thiopurines: A Systematic Review 2011 30 71 92%
AZATHIOPRINE AND 6-MERCAPTOPURINE IN CROHN DISEASE - A METAANALYSIS 1995 510 19 53%

Address terms


Rank Address term Relevance score
(tfidf)		 Class's shr.
of term's tot.
occurrences		 Shr. of publ.
in class containing
term		 Num. of
publ. in
class
1 UNIDAD TOXICOL MOL HEPAT 15 77% 0.5% 10
2 PURINE 8 27% 1.2% 24
3 PEDIAT ONCOL SE NETHERLANDS 6 100% 0.2% 4
4 HAEMATOL ONCOL OUTPATIENT 4 75% 0.1% 3
5 CLIN SCI CSUH 2 67% 0.1% 2
6 UMR S 1147 2 67% 0.1% 2
7 UNIT MOL CLIN PHARMACOL 2 67% 0.1% 2
8 UNITE PHARMACOL PEDIAT 2 67% 0.1% 2
9 SECT MED PHARMACOL 2 33% 0.2% 5
10 GYNECOL OBSTET PEDIAT 2 17% 0.4% 9

Related classes at same level (level 2)


Rank Relatedness score Related classes
1 0.0000022577 ULCERATIVE COLITIS//CROHNS DISEASE//INFLAMMATORY BOWEL DISEASE
2 0.0000008129 DIHYDROPYRIMIDINE DEHYDROGENASE//5 FLUOROURACIL//THYMIDINE PHOSPHORYLASE
3 0.0000007577 PRIMARY BILIARY CIRRHOSIS//AUTOIMMUNE HEPATITIS//PRIMARY SCLEROSING CHOLANGITIS
4 0.0000006994 FOLATE RECEPTOR//REDUCED FOLATE CARRIER//DIHYDROFOLATE REDUCTASE
5 0.0000006636 THYREOSTATS//CYSTEINE//TIOPRONIN
6 0.0000006467 GENETIC TESTING//JOURNAL OF GENETIC COUNSELING//GENETIC COUNSELING
7 0.0000005943 DIVERTICULITIS//ANAL FISTULA//DIVERTICULAR DISEASE
8 0.0000005878 HYPEREMESIS GRAVIDARUM//MOTHERISK PROGRAM//NAUSEA AND VOMITING OF PREGNANCY
9 0.0000005578 DEOXYCYTIDINE KINASE//PURINE NUCLEOSIDE PHOSPHORYLASE//NUCLEOSIDE TRANSPORT
10 0.0000005337 MYELODYSPLASTIC SYNDROMES//ACUTE MYELOID LEUKEMIA//LEUKEMIA