Class information for:
Level 2: LEFLUNOMIDE//LINOMIDE//MIZORIBINE

Basic class information

ID Publications Average number
of references
Avg. shr. active
ref. in WoS
3042 1966 26.4 76%



Bar chart of Publication_year

Last years might be incomplete

Classes in level above (level 3)



ID, lev.
above
Publications Label for level above
107 70336 TRANSPLANTATION//TRANSPLANTATION PROCEEDINGS//JOURNAL OF HEART AND LUNG TRANSPLANTATION

Classes in level below (level 1)



ID, lev. below Publications Label for level below
10430 998 LEFLUNOMIDE//DIHYDROOROTATE DEHYDROGENASE//DG RHEUMATOL
19581 434 DEOXYSPERGUALIN//15 DEOXYSPERGUALIN//AXE IMMUNOL
23507 288 MIZORIBINE//COMPARAT TRANSPLANTAT//ORAL MIZORIBINE PULSE THERAPY
24991 246 LINOMIDE//ROQUINIMEX//LAQUINIMOD

Terms with highest relevance score



Rank Term Type of term Relevance score
(tfidf)
Class's shr.
of term's tot.
occurrences
Shr. of publ.
in class containing
term
Num. of
publ. in
class
1 LEFLUNOMIDE Author keyword 175 50% 13% 249
2 LINOMIDE Author keyword 99 80% 3% 61
3 MIZORIBINE Author keyword 97 64% 5% 96
4 DIHYDROOROTATE DEHYDROGENASE Author keyword 87 76% 3% 62
5 DG RHEUMATOL Address 36 83% 1% 20
6 DG RHEUMATOL IMMUNOL Address 24 91% 1% 10
7 BREQUINAR Author keyword 23 76% 1% 16
8 DEOXYSPERGUALIN Author keyword 20 56% 1% 25
9 A771726 Author keyword 18 89% 0% 8
10 DIHYDROOROTATE DEHYDROGENASE DHODH Author keyword 18 89% 0% 8

Web of Science journal categories

Author Key Words



Rank Web of Science journal category Relevance score
(tfidf)
Class's shr.
of term's tot.
occurrences
Shr. of publ.
in class containing
term
Num. of
publ. in
class
LCSH search Wikipedia search
1 LEFLUNOMIDE 175 50% 13% 249 Search LEFLUNOMIDE Search LEFLUNOMIDE
2 LINOMIDE 99 80% 3% 61 Search LINOMIDE Search LINOMIDE
3 MIZORIBINE 97 64% 5% 96 Search MIZORIBINE Search MIZORIBINE
4 DIHYDROOROTATE DEHYDROGENASE 87 76% 3% 62 Search DIHYDROOROTATE+DEHYDROGENASE Search DIHYDROOROTATE+DEHYDROGENASE
5 BREQUINAR 23 76% 1% 16 Search BREQUINAR Search BREQUINAR
6 DEOXYSPERGUALIN 20 56% 1% 25 Search DEOXYSPERGUALIN Search DEOXYSPERGUALIN
7 A771726 18 89% 0% 8 Search A771726 Search A771726
8 DIHYDROOROTATE DEHYDROGENASE DHODH 18 89% 0% 8 Search DIHYDROOROTATE+DEHYDROGENASE+DHODH Search DIHYDROOROTATE+DEHYDROGENASE+DHODH
9 FK778 17 72% 1% 13 Search FK778 Search FK778
10 ROQUINIMEX 15 82% 0% 9 Search ROQUINIMEX Search ROQUINIMEX

Key Words Plus



Rank Web of Science journal category Relevance score
(tfidf)
Class's shr.
of term's tot.
occurrences
Shr. of publ.
in class containing
term
Num. of
publ. in
class
1 A77 1726 116 88% 3% 56
2 15 DEOXYSPERGUALIN 90 59% 5% 102
3 HWA 486 79 85% 2% 41
4 LEFLUNOMIDE 76 36% 9% 173
5 BREDININ 75 73% 3% 57
6 LS 2616 74 84% 2% 41
7 DEOXYSPERGUALIN 58 57% 3% 68
8 SPERGUALIN 56 76% 2% 39
9 NSC 368390 53 95% 1% 18
10 DIHYDROOROTATE DEHYDROGENASE 51 42% 5% 95

Journals

Reviews



Title Publ. year Cit. Active
references
% act. ref.
to same field
Immune mechanisms of new therapeutic strategies in MS - Teriflunomide 2012 33 49 80%
Clinical pharmacokinetics of leflunomide 2002 94 9 100%
Recent Developments in the Medicinal Chemistry and Therapeutic Potential of Dihydroorotate Dehydrogenase (DHODH) Inhibitors 2011 20 57 93%
Benefit-Risk Assessment of Leflunomide An Appraisal of Leflunomide in Rheumatoid Arthritis 10 Years After Licensing 2009 52 55 71%
Leflunomide: mode of action in the treatment of rheumatoid arthritis 2000 165 67 73%
Leflunomide in the treatment of rheumatoid arthritis 2004 45 43 91%
An update of teriflunomide for treatment of multiple sclerosis 2013 6 40 73%
Leflunomide for the treatment of rheumatoid arthritis: A systematic review and metaanalysis 2003 58 26 62%
Mizoribine: A New Approach in the Treatment of Renal Disease 2009 19 27 96%
Stimulation of the antiviral innate immune response by pyrimidine biosynthesis inhibitors: a surprise of phenotypic screening 2015 1 24 25%

Address terms



Rank Address term Relevance score
(tfidf)
Class's shr.
of term's tot.
occurrences
Shr. of publ.
in class containing
term
Num. of
publ. in
class
1 DG RHEUMATOL 36 83% 1.0% 20
2 DG RHEUMATOL IMMUNOL 24 91% 0.5% 10
3 COMPARAT TRANSPLANTAT 12 59% 0.7% 13
4 BEHRINGWERKE AG 8 100% 0.3% 5
5 AXE IMMUNOL 6 80% 0.2% 4
6 IMMUNOL DOMAIN 6 100% 0.2% 4
7 GLOBAL INNOVAT RD 5 63% 0.3% 5
8 CHEM GLOBAL HLTH 4 67% 0.2% 4
9 CRISTALOG PROT 4 41% 0.4% 7
10 PHARMA WERK KALLE ALBERT 3 100% 0.2% 3

Related classes at same level (level 2)



Rank Relatedness score Related classes
1 0.0000029052 XENOTRANSPLANTATION//PORCINE ENDOGENOUS RETROVIRUSES//PERV
2 0.0000014861 LESCH NYHAN SYNDROME//TIAZOFURIN//LESCH NYHAN DISEASE
3 0.0000013782 RHEUMATOID ARTHRITIS//RHEUMATOLOGY//RHEUMATOL
4 0.0000013147 TRANSPLANTATION//HAND TRANSPLANTATION//COMPOSITE TISSUE ALLOTRANSPLANTATION
5 0.0000012743 TRANSPLANTATION//TRANSPLANTATION PROCEEDINGS//MYCOPHENOLIC ACID
6 0.0000006789 TRIPTOLIDE//CELASTROL//TRIPTERYGIUM WILFORDII HOOK F
7 0.0000006273 MULTIPLE SCLEROSIS//MULTIPLE SCLEROSIS JOURNAL//NEUROMYELITIS OPTICA
8 0.0000005870 COLLAGEN INDUCED ARTHRITIS//SECT MED INFLAMMAT//INTERLEUKIN 1 RECEPTOR ANTAGONIST
9 0.0000005119 SYSTEMIC LUPUS ERYTHEMATOSUS//LUPUS//LUPUS NEPHRITIS
10 0.0000004731 LUNG TRANSPLANTATION//BRONCHIOLITIS OBLITERANS SYNDROME//CHRONIC LUNG ALLOGRAFT DYSFUNCTION