Class information for:
Level 2: HOMOCYSTEINE//FOLATE//FOLIC ACID

Basic class information
ID Publications Average number
of references		 Avg. shr. active
ref. in WoS
322 17515 37.5 73%


Bar chart of Publication_year

Last years might be incomplete

Classes in level above (level 3)


ID, lev.
above		 Publications Label for level above
263 40791 HOMOCYSTEINE//FOLATE//FOLIC ACID

Classes in level below (level 1)


ID, lev. below Publications Label for level below
58 4568 HOMOCYSTEINE//HYPERHOMOCYSTEINEMIA//FOLATE
1473 2549 NEURAL TUBE DEFECTS//FOLIC ACID//ANENCEPHALY
1793 2413 COBALAMIN//COBALAMIN DEFICIENCY//METHYLMALONIC ACID
3941 1802 MTHFR//FOLATE//METHYLENETETRAHYDROFOLATE REDUCTASE
6791 1366 FOOD FOLATE//FOLATE BIOAVAILABILITY//FOLATES
8452 1182 METHIONINE ADENOSYLTRANSFERASE//S ADENOSYLMETHIONINE//GLYCINE N METHYLTRANSFERASE
8704 1157 CELLULAR NEUROBIOL NEURODEGENERAT//PSYCHOGERIATRIC PATIENTS//STUDY PHYSIOPATHOL AGING
10550 988 CHOLINE DEFICIENCY//BETAINE//CHOLINE
14429 704 L METHYLFOLATE//ADEMETIONINE//METHYLENETETRAHYDROFOLATE REDUCTASE GENE MTHFR
21885 345 HOMOCYSTINURIA//CYSTATHIONINE BETA SYNTHASE//CYSTATHIONINE BETA SYNTHASE DEFICIENCY
25315 236 HOMOCYSTEINE THIOLACTONE//PROTEIN N HOMOCYSTEINYLATION//DIETARY HYPERHOMOCYSTEINEMIA
26592 205 ABT KLIN CHEM MED//BONE ARTHRIT CBAR GERIATR MED//DESIGNING FOODS IMPROVE NUTR FOOD SCI HUMAN

Terms with highest relevance score


Rank Term Type of term Relevance score
(tfidf)		 Class's shr.
of term's tot.
occurrences		 Shr. of publ.
in class containing
term		 Num. of publ.
in class
1 HOMOCYSTEINE Author keyword 3329 60% 21% 3633
2 FOLATE Author keyword 1505 57% 10% 1787
3 FOLIC ACID Author keyword 910 47% 8% 1449
4 VITAMIN B 12 Author keyword 637 44% 6% 1114
5 MTHFR Author keyword 504 61% 3% 531
6 NEURAL TUBE DEFECTS Author keyword 426 51% 3% 590
7 HYPERHOMOCYSTEINEMIA Author keyword 409 58% 3% 468
8 METHYLENETETRAHYDROFOLATE REDUCTASE Author keyword 372 63% 2% 379
9 COBALAMIN Author keyword 241 49% 2% 361
10 HOLOTRANSCOBALAMIN Author keyword 196 100% 0% 50

Web of Science journal categories

Author Key Words


Rank Web of Science journal category Relevance score
(tfidf)		 Class's shr.
of term's tot.
occurrences		 Shr. of publ.
in class containing
term		 Num. of publ.
in class		 LCSH search Wikipedia search
1 HOMOCYSTEINE 3329 60% 21% 3633 Search HOMOCYSTEINE Search HOMOCYSTEINE
2 FOLATE 1505 57% 10% 1787 Search FOLATE Search FOLATE
3 FOLIC ACID 910 47% 8% 1449 Search FOLIC+ACID Search FOLIC+ACID
4 VITAMIN B 12 637 44% 6% 1114 Search VITAMIN+B+12 Search VITAMIN+B+12
5 MTHFR 504 61% 3% 531 Search MTHFR Search MTHFR
6 NEURAL TUBE DEFECTS 426 51% 3% 590 Search NEURAL+TUBE+DEFECTS Search NEURAL+TUBE+DEFECTS
7 HYPERHOMOCYSTEINEMIA 409 58% 3% 468 Search HYPERHOMOCYSTEINEMIA Search HYPERHOMOCYSTEINEMIA
8 METHYLENETETRAHYDROFOLATE REDUCTASE 372 63% 2% 379 Search METHYLENETETRAHYDROFOLATE+REDUCTASE Search METHYLENETETRAHYDROFOLATE+REDUCTASE
9 COBALAMIN 241 49% 2% 361 Search COBALAMIN Search COBALAMIN
10 HOLOTRANSCOBALAMIN 196 100% 0% 50 Search HOLOTRANSCOBALAMIN Search HOLOTRANSCOBALAMIN

Key Words Plus


Rank Web of Science journal category Relevance score
(tfidf)		 Class's shr.
of term's tot.
occurrences		 Shr. of publ.
in class containing
term		 Num. of publ.
in class
1 PLASMA HOMOCYSTEINE 2137 60% 13% 2318
2 HYPERHOMOCYSTEINEMIA 1494 59% 10% 1664
3 FOLIC ACID 1253 43% 13% 2208
4 FOLATE 1161 50% 10% 1678
5 COMMON MUTATION 913 62% 5% 955
6 METHYLENETETRAHYDROFOLATE REDUCTASE 892 52% 7% 1226
7 HOMOCYSTEINE 854 37% 11% 1866
8 NEURAL TUBE DEFECTS 817 38% 10% 1728
9 VASCULAR DISEASE 729 28% 13% 2213
10 COBALAMIN DEFICIENCY 622 68% 3% 543

Journals


Rank Web of Science journal category Relevance score
(tfidf)		 Class's shr.
of term's tot.
occurrences		 Shr. of publ.
in class containing
term		 Num. of
publ. in
class
1 BIRTH DEFECTS RESEARCH PART A-CLINICAL AND MOLECULAR TERATOLOGY 39 18% 1% 202

Reviews


Title Publ. year Cit. Active references % act. ref.
to same field
A QUANTITATIVE ASSESSMENT OF PLASMA HOMOCYSTEINE AS A RISK FACTOR FOR VASCULAR-DISEASE - PROBABLE BENEFITS OF INCREASING FOLIC-ACID INTAKES 1995 2651 74 92%
Folate: Metabolism, genes, polymorphisms and the associated diseases 2014 24 129 87%
Homocysteine and risk of ischemic heart disease and stroke - A meta-analysis 2002 986 66 89%
Homocysteine and cardiovascular disease: evidence on causality from a meta-analysis 2002 1017 125 81%
Effects of Lowering Homocysteine Levels With B Vitamins on Cardiovascular Disease, Cancer, and Cause-Specific Mortality Meta-analysis of 8 Randomized Trials Involving 37 485 Individuals 2010 173 36 89%
Homocysteine and atherothrombosis 1998 1323 81 88%
Role of homocysteine in the development of cardiovascular disease 2015 3 14 86%
Homocysteine and cardiovascular disease 1998 1236 217 88%
Facts and recommendations about total homocysteine determinations: An expert opinion 2004 488 248 87%
MTHFR 677C -> T polymorphism and risk of coronary heart disease - A meta-analysis 2002 555 76 89%

Address terms


Rank Address term Relevance score
(tfidf)		 Class's shr.
of term's tot.
occurrences		 Shr. of publ.
in class containing
term		 Num. of
publ. in
class
1 LOCUS HOMOCYSTEINE RELATED VITAMINS 76 77% 0.3% 51
2 VITAMIN BIOAVAI IL 32 85% 0.1% 17
3 CHILD HLTH EPIDEMIOL 32 88% 0.1% 15
4 VITAMIN METAB 27 70% 0.1% 23
5 VITAMINS CARCINOGENESIS 27 63% 0.2% 27
6 NUTR SCI GENOM 20 100% 0.1% 9
7 CELLULAR NEUROBIOL NEURODEGENERAT 17 34% 0.2% 40
8 VITAMIN METAB AGING 15 67% 0.1% 14
9 HUMAN NUTR AGING 14 11% 0.7% 122
10 MOL PATHOGENESIS SECT 13 61% 0.1% 14

Related classes at same level (level 2)


Rank Relatedness score Related classes
1 0.0000010332 OVOTOXICITY//TIME TO PREGNANCY//ANTINEOPLASTIC DRUGS
2 0.0000008973 FOLATE RECEPTOR//REDUCED FOLATE CARRIER//DIHYDROFOLATE REDUCTASE
3 0.0000008853 THIAMINE DEFICIENCY//THIAMINE//WERNICKES ENCEPHALOPATHY
4 0.0000008676 THYREOSTATS//CYSTEINE//TIOPRONIN
5 0.0000007677 MENINGOMYELOCELE//SPINA BIFIDA//FETAL SURGERY
6 0.0000006422 DIHYDRODIPICOLINATE SYNTHASE//ASPARTATE KINASE//METHIONINE DEPENDENCE
7 0.0000006028 COENZYME B 12//ADENOSYLCOBALAMIN//COBALOXIMES
8 0.0000005504 LIPOYL DOMAIN//PYRUVATE DEHYDROGENASE COMPLEX//NONKETOTIC HYPERGLYCINEMIA
9 0.0000005352 MAPLE SYRUP URINE DISEASE//METHYLMALONIC ACIDEMIA//JOURNAL OF INHERITED METABOLIC DISEASE
10 0.0000004829 PARAOXONASE//PARAOXONASE 1//PON1