Class information for:
Level 2: OSTEOCLAST//RANKL//ICARIIN

Basic class information
ID Publications Average number
of references		 Avg. shr. active
ref. in WoS
350 16919 41.3 80%


Bar chart of Publication_year

Last years might be incomplete

Classes in level above (level 3)


ID, lev.
above		 Publications Label for level above
47 92315 OSTEOPOROSIS//OSTEOPOROSIS INTERNATIONAL//HYDROXYAPATITE

Classes in level below (level 1)


ID, lev. below Publications Label for level below
403 3443 RANKL//OSTEOCLAST//OSTEOCLASTOGENESIS
405 3441 RHBMP 2//BONE MORPHOGENETIC PROTEIN//RECOMBINANT HUMAN BONE MORPHOGENETIC PROTEIN 2
4360 1724 OSTEOCYTE//OSTEOCYTES//BONE FLUID FLOW
6528 1405 CLEIDOCRANIAL DYSPLASIA//RUNX2//OSTERIX
9104 1121 POSITIVE BONE BALANCE//PROSTAGLANDIN ESTRADIOL PGE2//ENDOCRINOL METAB MC1850
10930 955 DORSAL SKINFOLD CHAMBER//ABORAT PARTNER LARGE BONE DEFECT HEALING//INOSCULATION
11218 933 MARROW FIBROBLASTS//OSTEOPROGENITORS//OSTEOBLASTIC MARKERS
11399 918 GROWTH HORMONE BIOL//IN SITU SETTING CEMENT//POLYD L LACTIDE COATING
16166 603 ICARIIN//ICARITIN//EPIMEDIUM
16602 580 SKELETAL BIOTECH//FACILITATED ENDOGENOUS REPAIR//SKELETAL BIOTECHNOL
20487 397 PL BENCH CORE//ANTIDIARRHEIC//DRIED PLUM
22220 332 CELL PHYSIOL MOL IMAGE//ANESTHET TOXICOL//CELL BIOL MOL IMAGE
24509 259 LONGEV SCI//HOSP GERIATR MED//TORAT MED
24510 259 IPRIFLAVONE//TAK 778//ULMUS WALLICHIANA
25494 232 LIPID CHEM MOL BIOL//ENHANCING FOODS PROTECT HLTH//BONE BIOMECHANICAL STRENGTH
31338 124 OSTEOGENIC GROWTH PEPTIDE//IMMUN REGULAT//OGP10 14
32913 101 DRYNARIA FORTUNEI//DRYNARIAE RHIZOMA//DRYNARIA QUERCIFOLIA
33421 92 NELL 1//NELL2//DENT CRANIO IAL

Terms with highest relevance score


Rank Term Type of term Relevance score
(tfidf)		 Class's shr.
of term's tot.
occurrences		 Shr. of publ.
in class containing
term		 Num. of
publ. in
class
1 OSTEOCLAST Author keyword 294 30% 5% 836
2 RANKL Author keyword 279 42% 3% 516
3 ICARIIN Author keyword 250 75% 1% 180
4 RUNX2 Author keyword 202 49% 2% 298
5 OSTEOBLAST Author keyword 195 20% 5% 899
6 BONE MORPHOGENETIC PROTEIN Author keyword 188 34% 3% 460
7 CLEIDOCRANIAL DYSPLASIA Author keyword 180 82% 1% 105
8 OSTEOCYTE Author keyword 172 52% 1% 232
9 RHBMP 2 Author keyword 143 62% 1% 149
10 OSTEOCLASTOGENESIS Author keyword 138 41% 2% 264

Web of Science journal categories

Author Key Words


Rank Web of Science journal category Relevance score
(tfidf)		 Class's shr.
of term's tot.
occurrences		 Shr. of publ.
in class containing
term		 Num. of
publ. in
class		 LCSH search Wikipedia search
1 OSTEOCLAST 294 30% 5% 836 Search OSTEOCLAST Search OSTEOCLAST
2 RANKL 279 42% 3% 516 Search RANKL Search RANKL
3 ICARIIN 250 75% 1% 180 Search ICARIIN Search ICARIIN
4 RUNX2 202 49% 2% 298 Search RUNX2 Search RUNX2
5 OSTEOBLAST 195 20% 5% 899 Search OSTEOBLAST Search OSTEOBLAST
6 BONE MORPHOGENETIC PROTEIN 188 34% 3% 460 Search BONE+MORPHOGENETIC+PROTEIN Search BONE+MORPHOGENETIC+PROTEIN
7 CLEIDOCRANIAL DYSPLASIA 180 82% 1% 105 Search CLEIDOCRANIAL+DYSPLASIA Search CLEIDOCRANIAL+DYSPLASIA
8 OSTEOCYTE 172 52% 1% 232 Search OSTEOCYTE Search OSTEOCYTE
9 RHBMP 2 143 62% 1% 149 Search RHBMP+2 Search RHBMP+2
10 OSTEOCLASTOGENESIS 138 41% 2% 264 Search OSTEOCLASTOGENESIS Search OSTEOCLASTOGENESIS

Key Words Plus


Rank Web of Science journal category Relevance score
(tfidf)		 Class's shr.
of term's tot.
occurrences		 Shr. of publ.
in class containing
term		 Num. of
publ. in
class
1 RHBMP 2 459 64% 3% 444
2 MORPHOGENETIC PROTEIN 2 369 46% 4% 602
3 OSTEOPROTEGERIN LIGAND 355 50% 3% 511
4 RECEPTOR ACTIVATOR 317 34% 4% 750
5 OSTEOBLAST DIFFERENTIATION 219 24% 5% 813
6 CBFA1 214 52% 2% 289
7 CLEIDOCRANIAL DYSPLASIA 210 49% 2% 314
8 BONE MORPHOGENETIC PROTEIN 2 206 27% 4% 662
9 BONE RESORPTION 187 19% 5% 906
10 OSTEOCLAST DIFFERENTIATION FACTOR 177 52% 1% 239

Journals


Rank Web of Science journal category Relevance score
(tfidf)		 Class's shr.
of term's tot.
occurrences		 Shr. of publ.
in class containing
term		 Num. of
publ. in
class
1 BONE 102 12% 5% 770
2 JOURNAL OF BONE AND MINERAL RESEARCH 100 12% 5% 771
3 BONE AND MINERAL 13 13% 1% 93
4 EUROPEAN CELLS & MATERIALS 8 14% 0% 55
5 BONE RESEARCH 1 10% 0% 6

Reviews


Title Publ. year Cit. Active references % act. ref.
to same field
Osteoclast differentiation and activation 2003 2089 72 82%
A critical review of recombinant human bone morphogenetic protein-2 trials in spinal surgery: emerging safety concerns and lessons learned 2011 363 56 73%
Growth factors in orthopaedic surgery: demineralized bone matrix versus recombinant bone morphogenetic proteins 2015 4 78 88%
The Amazing Osteocyte 2011 369 87 60%
Effectiveness and Harms of Recombinant Human Bone Morphogenetic Protein-2 in Spine Fusion A Systematic Review and Meta-analysis 2013 84 60 73%
Review of vascularised bone tissue-engineering strategies with a focus on co-culture systems 2015 7 165 37%
Safety and Effectiveness of Recombinant Human Bone Morphogenetic Protein-2 for Spinal Fusion A Meta-analysis of Individual-Participant Data 2013 69 65 66%
Osteoimmunology: shared mechanisms and crosstalk between the immune and bone systems 2007 460 114 67%
Bone resorption by osteoclasts 2000 1562 51 61%
Complications with the use of bone morphogenetic protein 2 (BMP-2) in spine surgery 2014 15 62 82%

Address terms


Rank Address term Relevance score
(tfidf)		 Class's shr.
of term's tot.
occurrences		 Shr. of publ.
in class containing
term		 Num. of
publ. in
class
1 ORAL CELL BIOL 37 26% 0.7% 121
2 BONE TRANSPLANTAT GRP 26 100% 0.1% 11
3 CELL PHYSIOL MOL IMAGE 24 82% 0.1% 14
4 IMMUN REGULAT 24 91% 0.1% 10
5 BONE MINERAL DIS 18 24% 0.4% 65
6 OSTEOPOROSIS METAB BONE DIS 18 30% 0.3% 50
7 BONE UNIT 17 42% 0.2% 32
8 IMAGING SCI BASED LUNG BONE DIS 15 63% 0.1% 15
9 SKELETAL BIOTECH 14 55% 0.1% 18
10 REGULAT BONE METAB DIS 14 65% 0.1% 13

Related classes at same level (level 2)


Rank Relatedness score Related classes
1 0.0000012989 MICRODAMAGE//CORTICAL BONE//VIBROARTHROGRAPHY
2 0.0000012557 OSTEOPONTIN//DENTAL PULP//AMELOGENIN
3 0.0000012536 OSTEOPOROSIS//OSTEOPOROSIS INTERNATIONAL//BONE MINERAL DENSITY
4 0.0000012261 HYDROXYAPATITE//MATERIALS SCIENCE, BIOMATERIALS//BIOACTIVE GLASS
5 0.0000011994 OSTEOPETROSIS//MELORHEOSTOSIS//EAGLES SYNDROME
6 0.0000010964 BISPHOSPHONATES//ZOLEDRONIC ACID//BISPHOSPHONATE
7 0.0000010767 DISTRACTION OSTEOGENESIS//INTRAMEDULLARY NAILING//JOURNAL OF ORTHOPAEDIC TRAUMA
8 0.0000009349 HEREDITARY HEMORRHAGIC TELANGIECTASIA//ENDOGLIN//TGF BETA
9 0.0000008937 VASCULAR CALCIFICATION//FGF 23//CALCIPHYLAXIS
10 0.0000008399 CRANIOPLASTY//SYNDROME OF THE TREPHINED//SKULL DEFECT