Class information for:
Level 2: MICROSATELLITE INSTABILITY//LYNCH SYNDROME//HNPCC

Basic class information
ID Publications Average number
of references		 Avg. shr. active
ref. in WoS
580 13536 37.9 84%


Bar chart of Publication_year

Last years might be incomplete

Classes in level above (level 3)


ID, lev.
above		 Publications Label for level above
175 53899 COLONOSCOPY//BARRETTS ESOPHAGUS//ESOPHAGEAL CANCER

Classes in level below (level 1)


ID, lev. below Publications Label for level below
160 4045 MICROSATELLITE INSTABILITY//LYNCH SYNDROME//HNPCC
1661 2469 PANITUMUMAB//CETUXIMAB//METASTATIC COLORECTAL CANCER
4352 1725 FAMILIAL ADENOMATOUS POLYPOSIS//APC GENE//MUTYH
9570 1075 SERRATED ADENOMA//SESSILE SERRATED ADENOMA//TRADITIONAL SERRATED ADENOMA
11795 890 DNA MULTIPLOIDY//DNA PLOIDY//DNA PLOIDY HETEROGENEITY
11820 887 ABERRANT CRYPT FOCI//BETA CATENIN ACCUMULATED CRYPTS//COLON CARCINOGENESIS
16952 561 HUMAN CYTOGENET TOXICOL GENET//C KI RAS ONCOGENE//JOAO BARROS BARRETO UNIV HOSP
19353 445 INTER SIMPLE SEQUENCE REPEAT PCR//BIOPHYS CYTOMETRY//HOSP UNIV SALAMANCA IBSAL
20168 410 FLAT ADENOMA//DEPRESSED ADENOMA//POLYPOID GROWTH
21000 376 COLONIC EFFLUENT//STOOL DNA//FECAL RNA
21762 349 MIN MOUSE//MIN MICE//FAP MODEL
23041 304 KIAA1199//MIR 188 5P//TRANSCRIPTOMIC PROFILES

Terms with highest relevance score


Rank Term Type of term Relevance score
(tfidf)		 Class's shr.
of term's tot.
occurrences		 Shr. of publ.
in class containing
term		 Num. of publ.
in class
1 MICROSATELLITE INSTABILITY Author keyword 1026 60% 8% 1114
2 LYNCH SYNDROME Author keyword 751 75% 4% 541
3 HNPCC Author keyword 576 75% 3% 420
4 HEREDITARY NONPOLYPOSIS COLORECTAL CANCER Author keyword 264 74% 1% 194
5 COLORECTAL CANCER Author keyword 262 12% 16% 2110
6 PANITUMUMAB Author keyword 256 69% 2% 219
7 SERRATED ADENOMA Author keyword 219 92% 1% 85
8 MLH1 Author keyword 200 60% 2% 218
9 HMLH1 Author keyword 195 66% 1% 179
10 KRAS Author keyword 166 34% 3% 405

Web of Science journal categories

Author Key Words


Rank Web of Science journal category Relevance score
(tfidf)		 Class's shr.
of term's tot.
occurrences		 Shr. of publ.
in class containing
term		 Num. of publ.
in class		 LCSH search Wikipedia search
1 MICROSATELLITE INSTABILITY 1026 60% 8% 1114 Search MICROSATELLITE+INSTABILITY Search MICROSATELLITE+INSTABILITY
2 LYNCH SYNDROME 751 75% 4% 541 Search LYNCH+SYNDROME Search LYNCH+SYNDROME
3 HNPCC 576 75% 3% 420 Search HNPCC Search HNPCC
4 HEREDITARY NONPOLYPOSIS COLORECTAL CANCER 264 74% 1% 194 Search HEREDITARY+NONPOLYPOSIS+COLORECTAL+CANCER Search HEREDITARY+NONPOLYPOSIS+COLORECTAL+CANCER
5 COLORECTAL CANCER 262 12% 16% 2110 Search COLORECTAL+CANCER Search COLORECTAL+CANCER
6 PANITUMUMAB 256 69% 2% 219 Search PANITUMUMAB Search PANITUMUMAB
7 SERRATED ADENOMA 219 92% 1% 85 Search SERRATED+ADENOMA Search SERRATED+ADENOMA
8 MLH1 200 60% 2% 218 Search MLH1 Search MLH1
9 HMLH1 195 66% 1% 179 Search HMLH1 Search HMLH1
10 KRAS 166 34% 3% 405 Search KRAS Search KRAS

Key Words Plus


Rank Web of Science journal category Relevance score
(tfidf)		 Class's shr.
of term's tot.
occurrences		 Shr. of publ.
in class containing
term		 Num. of publ.
in class
1 MICROSATELLITE INSTABILITY 1015 35% 17% 2348
2 NONPOLYPOSIS COLORECTAL CANCER 930 51% 10% 1307
3 HNPCC 820 80% 4% 513
4 LYNCH SYNDROME 636 61% 5% 679
5 HMLH1 553 71% 3% 450
6 MISMATCH REPAIR GENES 397 72% 2% 308
7 NONPOLYPOSIS COLON CANCER 385 58% 3% 439
8 HMSH2 352 77% 2% 239
9 CETUXIMAB PLUS IRINOTECAN 350 72% 2% 277
10 PANITUMUMAB 332 73% 2% 254

Journals


Rank Web of Science journal category Relevance score
(tfidf)		 Class's shr.
of term's tot.
occurrences		 Shr. of publ.
in class containing
term		 Num. of
publ. in
class
1 FAMILIAL CANCER 67 28% 2% 208
2 CLINICAL COLORECTAL CANCER 30 26% 1% 99
3 HEREDITARY CANCER IN CLINICAL PRACTICE 9 22% 0% 35

Reviews


Title Publ. year Cit. Active references % act. ref.
to same field
Extended RAS mutations and anti-EGFR monoclonal antibody survival benefit in metastatic colorectal cancer: a meta-analysis of randomized, controlled trials 2015 12 15 100%
Lessons from hereditary colorectal cancer 1996 3252 87 62%
Colorectal serrated pathway cancers and precursors 2015 5 104 89%
Genomic medicine - Hereditary colorectal cancer 2003 865 77 68%
Predictive role of BRAF mutations in patients with advanced colorectal cancer receiving cetuximab and panitumumab: A meta-analysis 2015 5 32 81%
BRAF(V600E) Mutation and Its Association with Clinicopathological Features of Colorectal Cancer: A Systematic Review and Meta-Analysis 2014 20 36 94%
Revised guidelines for the clinical management of Lynch syndrome (HNPCC): recommendations by a group of European experts 2013 83 109 72%
Classification of colorectal cancer based on correlation of clinical, morphological and molecular features 2007 484 151 67%
The predictive value of KRAS, NRAS, BRAF, PIK3CA and PTEN for anti-EGFR treatment in metastatic colorectal cancer: A systematic review and meta-analysis 2014 20 36 86%
Systematic review of microsatellite instability and colorectal cancer prognosis 2005 630 79 63%

Address terms


Rank Address term Relevance score
(tfidf)		 Class's shr.
of term's tot.
occurrences		 Shr. of publ.
in class containing
term		 Num. of
publ. in
class
1 CONJOINT GASTROENTEROL 63 66% 0.4% 59
2 DANISH HNPCC REGISTER 35 86% 0.1% 18
3 DIGEST ONCOL UNIT 35 39% 0.5% 71
4 NEW ZEALAND FAMILIAL GASTROINTESTINAL CANC REGIST 31 92% 0.1% 12
5 ONCOL SPERIMENTALE 1 27 92% 0.1% 11
6 MOL POPULAT GENET 26 29% 0.6% 77
7 FAMILIAL GASTROINTESTINAL CANC REGISTRY 25 66% 0.2% 23
8 NETHERLANDS FDN DETECT HEREDITARY TUMOURS 22 62% 0.2% 23
9 GRP HUMAN GENET 22 53% 0.2% 29
10 BIOPHYS CYTOMETRY 21 85% 0.1% 11

Related classes at same level (level 2)


Rank Relatedness score Related classes
1 0.0000014602 CHROMATIN SUPRAORGANIZATION//ZNF703//NUCLEAR PHENOTYPES
2 0.0000013483 COLONOSCOPY//ENDOSCOPIC SUBMUCOSAL DISSECTION//COLORECTAL CANCER SCREENING
3 0.0000012438 DIHYDROPYRIMIDINE DEHYDROGENASE//5 FLUOROURACIL//THYMIDINE PHOSPHORYLASE
4 0.0000011943 HETEROTOPIC PANCREAS//HETEROTOPIC GASTRIC MUCOSA//ECTOPIC PANCREAS
5 0.0000011115 BARRETTS ESOPHAGUS//BARRETTS OESOPHAGUS//ESOPHAGEAL ADENOCARCINOMA
6 0.0000010552 BRCA1//BRCA2//CHEK2
7 0.0000009371 GENET CELL BIOL SECTCHUO KU//WNT//GENET CELL BIOL SECT
8 0.0000008444 ANALYTICAL AND QUANTITATIVE CYTOLOGY AND HISTOLOGY//CYTOMETRY//IMAGE CYTOMETRY
9 0.0000006916 INTUSSUSCEPTION//PEUTZ JEGHERS SYNDROME//MR ENTEROGRAPHY
10 0.0000006872 HAND FOOT SYNDROME//RADIATION RECALL//EXTRAVASATION