Class information for:
Level 2: CYCLOOXYGENASE 2//COX 2//CYCLOOXYGENASE

Basic class information
ID Publications Average number
of references		 Avg. shr. active
ref. in WoS
670 12541 40.3 82%


Bar chart of Publication_year

Last years might be incomplete

Classes in level above (level 3)


ID, lev.
above		 Publications Label for level above
189 51017 CLOPIDOGREL//PLATELETS//PRASUGREL

Classes in level below (level 1)


ID, lev. below Publications Label for level below
203 3878 CYCLOOXYGENASE 2//COX 2//CELECOXIB
2477 2163 PROSTAGLANDIN H SYNTHASE//IMRECOXIB//AB HANCOCK JR MEM CANC
4550 1693 THROMBOXANE A2 RECEPTOR//THROMBOXANE RECEPTOR//THROMBOXANE A2
7818 1246 ONO 1301//IP RECEPTOR//EP4 RECEPTOR
10081 1030 CRTH2//MOL BEHAV BIOL//PROSTAGLANDIN D 2
14698 686 NEUROINFLAMMAT S//MOL NEUROSCI UNIT//BUTAPROST
17744 521 GEORGE M OBRIEN KIDNEY UROL DIS//GEORGE OBRIEN KIDNEY UROL DIS//SERV 151 E
18805 469 MPGES 1//PROSTAGLANDIN E SYNTHASE//MPGES 2
23169 300 CYCLOOXYGENASE 2 GENE//PTGS2//COX 2 GENE
24169 269 15 HYDROXYPROSTAGLANDIN DEHYDROGENASE//PROSTAGLANDIN TRANSPORTER//15 PGDH
25871 222 EXPT THER EUT PHARMACOINFORMAT//PROSTACYCLIN SYNTHASE GENE//PROSTACYCLIN SYNTHASE
34708 64 SALICYLIDENEAMINO 2 THIOPHENOL//GAMABUFOTALIN//INFLAMMATION CONTROL

Terms with highest relevance score


Rank Term Type of term Relevance score
(tfidf)		 Class's shr.
of term's tot.
occurrences		 Shr. of publ.
in class containing
term		 Num. of
publ. in
class
1 CYCLOOXYGENASE 2 Author keyword 298 28% 7% 896
2 COX 2 Author keyword 245 26% 6% 796
3 CYCLOOXYGENASE Author keyword 187 23% 6% 725
4 CELECOXIB Author keyword 119 28% 3% 370
5 CRTH2 Author keyword 98 74% 1% 72
6 MPGES 1 Author keyword 93 70% 1% 77
7 MOL BEHAV BIOL Address 84 49% 1% 124
8 DP RECEPTOR Author keyword 76 93% 0% 28
9 THROMBOXANE A2 RECEPTOR Author keyword 63 67% 0% 56
10 PROSTAGLANDIN D 2 Author keyword 59 40% 1% 114

Web of Science journal categories

Author Key Words


Rank Web of Science journal category Relevance score
(tfidf)		 Class's shr.
of term's tot.
occurrences		 Shr. of publ.
in class containing
term		 Num. of
publ. in
class		 LCSH search Wikipedia search
1 CYCLOOXYGENASE 2 298 28% 7% 896 Search CYCLOOXYGENASE+2 Search CYCLOOXYGENASE+2
2 COX 2 245 26% 6% 796 Search COX+2 Search COX+2
3 CYCLOOXYGENASE 187 23% 6% 725 Search CYCLOOXYGENASE Search CYCLOOXYGENASE
4 CELECOXIB 119 28% 3% 370 Search CELECOXIB Search CELECOXIB
5 CRTH2 98 74% 1% 72 Search CRTH2 Search CRTH2
6 MPGES 1 93 70% 1% 77 Search MPGES+1 Search MPGES+1
7 DP RECEPTOR 76 93% 0% 28 Search DP+RECEPTOR Search DP+RECEPTOR
8 THROMBOXANE A2 RECEPTOR 63 67% 0% 56 Search THROMBOXANE+A2+RECEPTOR Search THROMBOXANE+A2+RECEPTOR
9 PROSTAGLANDIN D 2 59 40% 1% 114 Search PROSTAGLANDIN+D+2 Search PROSTAGLANDIN+D+2
10 PROSTAGLANDIN 54 13% 3% 386 Search PROSTAGLANDIN Search PROSTAGLANDIN

Key Words Plus


Rank Web of Science journal category Relevance score
(tfidf)		 Class's shr.
of term's tot.
occurrences		 Shr. of publ.
in class containing
term		 Num. of publ.
in class
1 PROSTANOID RECEPTORS 324 44% 4% 551
2 ASPIRIN USE 297 54% 3% 378
3 NONSTEROIDAL ANTIINFLAMMATORY DRUGS 280 13% 16% 1950
4 COX 2 250 35% 5% 588
5 D SYNTHETASE 198 87% 1% 98
6 CYCLOOXYGENASE 2 167 17% 7% 888
7 CYCLOOXYGENASE 2 EXPRESSION 161 26% 4% 547
8 INDUCIBLE CYCLOOXYGENASE 147 40% 2% 284
9 H SYNTHASE 132 60% 1% 144
10 CELECOXIB 130 25% 4% 449

Journals


Rank Web of Science journal category Relevance score
(tfidf)		 Class's shr.
of term's tot.
occurrences		 Shr. of publ.
in class containing
term		 Num. of
publ. in
class
1 PROSTAGLANDINS & OTHER LIPID MEDIATORS 26 12% 2% 192
2 ADVANCES IN PROSTAGLANDIN THROMBOXANE AND LEUKOTRIENE RESEARCH 8 11% 1% 72

Reviews


Title Publ. year Cit. Active references % act. ref.
to same field
Estimates of benefits and harms of prophylactic use of aspirin in the general population 2015 16 45 49%
Prostaglandin E receptors 2007 474 64 81%
The COX-2/PGE(2) pathway: key roles in the hallmarks of cancer and adaptation to the tumour microenvironment 2009 377 157 55%
Eicosanoids and cancer 2010 397 148 39%
Aspirin and non-steroidal anti-inflammatory drugs for cancer prevention: an international consensus statement 2009 242 56 71%
Prostaglandin endoperoxide H synthases (cyclooxygenases)-1 and -2 1996 1433 66 89%
Nonsteroidal anti-inflammatory drugs as anticancer agents: Mechanistic, pharmacologic, and clinical issues 2002 790 185 76%
Cyclooxygenases 1 and 2 1998 1863 104 63%
Cyclooxygenases: Structural, cellular, and molecular biology 2000 1594 247 65%
Aspirin and cancer risk: a quantitative review to 2011 2012 80 104 80%

Address terms


Rank Address term Relevance score
(tfidf)		 Class's shr.
of term's tot.
occurrences		 Shr. of publ.
in class containing
term		 Num. of
publ. in
class
1 MOL BEHAV BIOL 84 49% 1.0% 124
2 EXPT THER EUT PHARMACOINFORMAT 33 83% 0.2% 19
3 MINASE 19 27% 0.5% 62
4 AB HANCOCK JR MEM CANC 17 44% 0.2% 30
5 C PIER 13 71% 0.1% 10
6 GEORGE M OBRIEN KIDNEY UROL DIS 12 49% 0.1% 18
7 EXPT CARCINOGENESIS MUTAGENESIS 10 63% 0.1% 10
8 DISCOVERY 1 8 70% 0.1% 7
9 GEORGE OBRIEN KIDNEY UROL DIS 8 100% 0.0% 5
10 SERV 151 E 6 80% 0.0% 4

Related classes at same level (level 2)


Rank Relatedness score Related classes
1 0.0000022921 I EM NEURODEGENERAT BRAIN//BERAPROST SODIUM//IBUDILAST
2 0.0000014996 NSAIDS//NABUMETONE//ROFECOXIB
3 0.0000012923 5 LIPOXYGENASE//EXPT THER EUT REPERFUS INJURY//LEUKOTRIENES
4 0.0000011981 CITICOLINE//CLORICROMENE//CDP CHOLINE
5 0.0000008862 GLASGOW PROGNOSTIC SCORE//NEUTROPHIL TO LYMPHOCYTE RATIO//NEUTROPHIL LYMPHOCYTE RATIO
6 0.0000007163 PPAR GAMMA//PIOGLITAZONE//ROSIGLITAZONE
7 0.0000005525 CLOPIDOGREL//PRASUGREL//ASPIRIN RESISTANCE
8 0.0000005181 I KAPPA B//C REL//IKK
9 0.0000005107 REBAMIPIDE//GASTRIC MUCOSAL BLOOD FLOW//GASTRIC MUCOSA
10 0.0000004781 SOLUBLE EPOXIDE HYDROLASE//EPOXYEICOSATRIENOIC ACIDS//EPOXIDE HYDROLASE