Class information for:
Level 3: HER 2//TRASTUZUMAB//CHRONIC MYELOID LEUKEMIA

Basic class information
ID Publications Average number
of references		 Avg. shr. active
ref. in WoS
100 72119 45.1 88%


Bar chart of Publication_year

Last years might be incomplete

Classes in level above (level 4)


ID, lev.
above		 Publications Label for level above
0 3633673 BIOCHEMISTRY & MOLECULAR BIOLOGY//CELL BIOLOGY//MED

Classes in level below (level 2)


ID, lev.
below		 Publications Label for level below
313 17635 X LINKED AGAMMAGLOBULINEMIA//BRUTONS TYROSINE KINASE//BTK
451 15419 HER 2//TRASTUZUMAB//LAPATINIB
625 13166 PTEN//MTOR//LHERMITTE DUCLOS DISEASE
989 10020 CHRONIC MYELOID LEUKEMIA//IMATINIB//BCR ABL
1710 6112 FARNESYLTRANSFERASE//PALMITOYLATION//RLIP76
2513 3376 FOCAL ADHESION KINASE//INTEGRIN LINKED KINASE//FAK
2578 3204 CAVEOLIN 1//CAVEOLAE//CAVEOLIN
2824 2502 TETRASPANIN//CD9//CD151
3766 685 IQGAP1//LRIG1//MIG 6

Terms with highest relevance score


Rank Term Type of term Relevance score
(tfidf)		 Class's shr.
of term's tot.
occurrences		 Shr. of publ.
in class containing
term		 Num. of publ.
in class
1 HER 2 Author keyword 719 43% 2% 1262
2 TRASTUZUMAB Author keyword 660 53% 1% 881
3 CHRONIC MYELOID LEUKEMIA Author keyword 521 45% 1% 868
4 DASATINIB Author keyword 430 67% 1% 383
5 PTEN Author keyword 428 39% 1% 876
6 IMATINIB Author keyword 416 39% 1% 850
7 BCR ABL Author keyword 405 48% 1% 613
8 CAVEOLIN 1 Author keyword 347 51% 1% 492
9 NILOTINIB Author keyword 334 70% 0% 274
10 CAVEOLAE Author keyword 292 46% 1% 468

Web of Science journal categories

Author Key Words


Rank Web of Science journal category Relevance score
(tfidf)		 Class's shr.
of term's tot.
occurrences		 Shr. of publ.
in class containing
term		 Num. of publ.
in class		 LCSH search Wikipedia search
1 HER 2 719 43% 2% 1262 Search HER+2 Search HER+2
2 TRASTUZUMAB 660 53% 1% 881 Search TRASTUZUMAB Search TRASTUZUMAB
3 CHRONIC MYELOID LEUKEMIA 521 45% 1% 868 Search CHRONIC+MYELOID+LEUKEMIA Search CHRONIC+MYELOID+LEUKEMIA
4 DASATINIB 430 67% 1% 383 Search DASATINIB Search DASATINIB
5 PTEN 428 39% 1% 876 Search PTEN Search PTEN
6 IMATINIB 416 39% 1% 850 Search IMATINIB Search IMATINIB
7 BCR ABL 405 48% 1% 613 Search BCR+ABL Search BCR+ABL
8 CAVEOLIN 1 347 51% 1% 492 Search CAVEOLIN+1 Search CAVEOLIN+1
9 NILOTINIB 334 70% 0% 274 Search NILOTINIB Search NILOTINIB
10 CAVEOLAE 292 46% 1% 468 Search CAVEOLAE Search CAVEOLAE

Key Words Plus


Rank Web of Science journal category Relevance score
(tfidf)		 Class's shr.
of term's tot.
occurrences		 Shr. of publ.
in class containing
term		 Num. of publ.
in class
1 CHRONIC MYELOGENOUS LEUKEMIA 865 28% 4% 2584
2 ANTIGEN RECEPTOR 735 32% 3% 1926
3 PHOSPHATIDYLINOSITOL 3 KINASE 725 24% 4% 2642
4 EGF RECEPTOR 703 33% 2% 1762
5 BCR ABL 634 42% 2% 1154
6 MAMMALIAN TARGET 633 32% 2% 1639
7 GROWTH FACTOR RECEPTOR 621 16% 5% 3584
8 CHRONIC MYELOID LEUKEMIA 617 26% 3% 2087
9 NEU ONCOGENE 612 54% 1% 797
10 CYTOGENETIC RESPONSES 575 74% 1% 429

Journals


Rank Web of Science journal category Relevance score
(tfidf)		 Class's shr.
of term's tot.
occurrences		 Shr. of publ.
in class containing
term		 Num. of publ.
in class
1 ONCOGENE 205 11% 3% 1823
2 IMMUNITY 49 12% 1% 380
3 CELLULAR SIGNALLING 47 11% 1% 426
4 NATURE IMMUNOLOGY 23 10% 0% 208
5 ONCOGENE RESEARCH 21 31% 0% 55
6 SCIENCE SIGNALING 20 12% 0% 155
7 CURRENT TOPICS IN MICROBIOLOGY AND IMMUNOLOGY 14 11% 0% 119
8 CLINICAL BREAST CANCER 8 11% 0% 69
9 TARGETED ONCOLOGY 5 13% 0% 39
10 CELL COMMUNICATION AND SIGNALING 5 12% 0% 39

Reviews


Title Publ. year Cit. Active references % act. ref.
to same field
mTOR Signaling in Growth Control and Disease 2012 1325 172 67%
mTOR: from growth signal integration to cancer, diabetes and ageing 2011 1183 170 52%
PI3K and cancer: lessons, challenges and opportunities 2014 149 215 55%
TOR signaling in growth and metabolism 2006 2539 109 54%
AKT/PKB signaling: Navigating downstream 2007 2173 109 46%
Targeting PI3K signalling in cancer: opportunities, challenges and limitations 2009 875 150 77%
European LeukemiaNet recommendations for the management of chronic myeloid leukemia: 2013 2013 153 137 97%
The phosphatidylinositol 3-kinase-AKT pathway in human cancer 2002 3114 151 69%
Targeting the phosphoinositide 3-kinase pathway in cancer 2009 779 195 83%
PI3K in cancer: divergent roles of isoforms, modes of activation and therapeutic targeting 2015 9 195 85%

Address terms


Rank Address term Relevance score
(tfidf)		 Class's shr.
of term's tot.
occurrences		 Shr. of publ.
in class containing
term		 Num. of
publ. in
class
1 LEUKEMIA 65 17% 0.5% 359
2 MOL CELLULAR ONCOL 36 18% 0.3% 183
3 LYMPHOCYTE INTERACT 33 67% 0.0% 30
4 CELLULAR INJURY 32 45% 0.1% 54
5 INOSITIDE 31 44% 0.1% 53
6 IMMUNE CELL BIOL 27 29% 0.1% 78
7 SIGNAL TRANSDUCT 26 11% 0.3% 219
8 LYMPHOCYTE BIOL SECT 25 36% 0.1% 57
9 MOL CELL BIOL TUMOR BIOL 25 75% 0.0% 18
10 PROGRAM MOL PATHOGENESIS 25 46% 0.1% 40

Related classes at same level (level 3)


Rank Relatedness score Related classes
1 0.0000004729 NOONAN SYNDROME//COSTELLO SYNDROME//PROTEIN TYROSINE PHOSPHATASE
2 0.0000003534 TRANSCRIPTION FACTOR//ETS 1//C JUN
3 0.0000002522 CD44//HYALURONAN//INTEGRIN
4 0.0000002355 VITILIGO//TYROSINASE//MELANOGENESIS
5 0.0000002215 DICTYOSTELIUM//JOURNAL OF MUSCLE RESEARCH AND CELL MOTILITY//DICTYOSTELIUM DISCOIDEUM
6 0.0000002163 KAWASAKI DISEASE//MUCOCUTANEOUS LYMPH NODE SYNDROME//SUPERANTIGEN
7 0.0000002025 AUTOPHAGY//TRAIL//APOPTOSIS
8 0.0000001994 SNAKE VENOM//SPHINGOSINE 1 PHOSPHATE//CERAMIDE
9 0.0000001822 MERKEL CELL CARCINOMA//P53//JC VIRUS
10 0.0000001771 TISSUE ANTIGENS//ANKYLOSING SPONDYLITIS//IMMUNOGENETICS