Class information for:
Level 3: CYTOCHROME P450//GSTM1//GSTT1

Basic class information
ID Publications Average number
of references		 Avg. shr. active
ref. in WoS
408 26180 40.2 76%


Bar chart of Publication_year

Last years might be incomplete

Classes in level above (level 4)


ID, lev.
above		 Publications Label for level above
0 3633673 BIOCHEMISTRY & MOLECULAR BIOLOGY//CELL BIOLOGY//MED

Classes in level below (level 2)


ID, lev.
below		 Publications Label for level below
395 16247 CYTOCHROME P450//CYP2D6//PREGNANE X RECEPTOR
1804 5742 GSTM1//GSTT1//GLUTATHIONE S TRANSFERASE
2568 3236 SOLUBLE EPOXIDE HYDROLASE//EPOXYEICOSATRIENOIC ACIDS//EPOXIDE HYDROLASE
3556 955 FLAVIN CONTAINING MONOOXYGENASE//FMO3//TRIMETHYLAMINURIA

Terms with highest relevance score


Rank Term Type of term Relevance score
(tfidf)		 Class's shr.
of term's tot.
occurrences		 Shr. of publ.
in class containing
term		 Num. of publ.
in class
1 CYTOCHROME P450 Author keyword 715 30% 8% 2008
2 GSTM1 Author keyword 502 72% 2% 397
3 GSTT1 Author keyword 467 76% 1% 330
4 SOLUBLE EPOXIDE HYDROLASE Author keyword 378 87% 1% 186
5 CYP2D6 Author keyword 339 49% 2% 506
6 EPOXIDE HYDROLASE Author keyword 268 66% 1% 247
7 PREGNANE X RECEPTOR Author keyword 229 71% 1% 187
8 GLUTATHIONE S TRANSFERASE Author keyword 227 26% 3% 752
9 EPOXYEICOSATRIENOIC ACIDS Author keyword 226 77% 1% 154
10 DRUG METABOLISM AND DISPOSITION Journal 221 17% 5% 1205

Web of Science journal categories

Author Key Words


Rank Web of Science journal category Relevance score
(tfidf)		 Class's shr.
of term's tot.
occurrences		 Shr. of publ.
in class containing
term		 Num. of publ.
in class		 LCSH search Wikipedia search
1 CYTOCHROME P450 715 30% 8% 2008 Search CYTOCHROME+P450 Search CYTOCHROME+P450
2 GSTM1 502 72% 2% 397 Search GSTM1 Search GSTM1
3 GSTT1 467 76% 1% 330 Search GSTT1 Search GSTT1
4 SOLUBLE EPOXIDE HYDROLASE 378 87% 1% 186 Search SOLUBLE+EPOXIDE+HYDROLASE Search SOLUBLE+EPOXIDE+HYDROLASE
5 CYP2D6 339 49% 2% 506 Search CYP2D6 Search CYP2D6
6 EPOXIDE HYDROLASE 268 66% 1% 247 Search EPOXIDE+HYDROLASE Search EPOXIDE+HYDROLASE
7 PREGNANE X RECEPTOR 229 71% 1% 187 Search PREGNANE+X+RECEPTOR Search PREGNANE+X+RECEPTOR
8 GLUTATHIONE S TRANSFERASE 227 26% 3% 752 Search GLUTATHIONE+S+TRANSFERASE Search GLUTATHIONE+S+TRANSFERASE
9 EPOXYEICOSATRIENOIC ACIDS 226 77% 1% 154 Search EPOXYEICOSATRIENOIC+ACIDS Search EPOXYEICOSATRIENOIC+ACIDS
10 EPOXYEICOSATRIENOIC ACID 186 80% 0% 117 Search EPOXYEICOSATRIENOIC+ACID Search EPOXYEICOSATRIENOIC+ACID

Key Words Plus


Rank Web of Science journal category Relevance score
(tfidf)		 Class's shr.
of term's tot.
occurrences		 Shr. of publ.
in class containing
term		 Num. of publ.
in class
1 GSTM1 695 68% 2% 610
2 EPOXYEICOSATRIENOIC ACIDS 672 67% 2% 614
3 GSTT1 530 73% 2% 410
4 DRUG METABOLISM 478 33% 5% 1211
5 PREGNANE X RECEPTOR 435 42% 3% 789
6 HUMAN LIVER MICROSOMES 434 28% 5% 1313
7 CONSTITUTIVE ANDROSTANE RECEPTOR 431 51% 2% 601
8 P 450 REDUCTASE 341 66% 1% 317
9 20 HYDROXYEICOSATETRAENOIC ACID 331 77% 1% 225
10 DEBRISOQUINE 315 52% 2% 429

Journals


Rank Web of Science journal category Relevance score
(tfidf)		 Class's shr.
of term's tot.
occurrences		 Shr. of publ.
in class containing
term		 Num. of publ.
in class
1 DRUG METABOLISM AND DISPOSITION 221 17% 5% 1205
2 PHARMACOGENETICS 121 32% 1% 307
3 XENOBIOTICA 78 14% 2% 518
4 CURRENT DRUG METABOLISM 37 19% 1% 179
5 DRUG METABOLISM REVIEWS 29 17% 1% 159
6 DRUG METABOLISM AND PHARMACOKINETICS 21 17% 0% 111

Reviews


Title Publ. year Cit. Active references % act. ref.
to same field
Cytochrome P450 enzymes in drug metabolism: Regulation of gene expression, enzyme activities, and impact of genetic variation 2013 173 551 40%
The glutathione S-Transferase supergene family: Regulation of GST and the contribution of the isoenzymes to cancer chemoprotection and drug resistance 1995 2431 657 58%
Cytochrome P-450 epoxygenase pathway of polyunsaturated fatty acid metabolism 2015 3 159 92%
P450(BM3) (CYP102A1): connecting the dots 2012 102 408 84%
Glutathione transferases 2005 1512 157 40%
Cytochrome P450 monooxygenases: an update on perspectives for synthetic application 2012 91 80 80%
EPOXIDES AND SOLUBLE EPOXIDE HYDROLASE IN CARDIOVASCULAR PHYSIOLOGY 2012 80 324 86%
Cytochrome P450 eicosanoids in hypertension and renal disease 2015 2 75 83%
Impact of Soluble Epoxide Hydrolase and Epoxyeicosanoids on Human Health 2013 35 127 93%
P-450 metabolites of arachidonic acid in the control of cardiovascular function 2002 714 480 64%

Address terms


Rank Address term Relevance score
(tfidf)		 Class's shr.
of term's tot.
occurrences		 Shr. of publ.
in class containing
term		 Num. of
publ. in
class
1 PHARMACOGENET SECT 97 54% 0.5% 126
2 PHARMACOKINET BIOANAL 46 61% 0.2% 49
3 MOL TOXICOL 44 14% 1.1% 291
4 DRUG METAB 35 14% 0.9% 223
5 GRP BIOCATALYSE CHIM FINE 20 62% 0.1% 21
6 IAN POTTER FDN PROT CRYSTALLOG 18 67% 0.1% 16
7 REPROD DEV TOXICOL 17 16% 0.4% 95
8 DRUG METAB MOL TOXICOL 15 29% 0.2% 43
9 SECT DEV PHARMACOL EXPT THER EUT 15 56% 0.1% 18
10 PROT STRUCT FUNCT PROGRAMME 15 71% 0.0% 12

Related classes at same level (level 3)


Rank Relatedness score Related classes
1 0.0000004980 KERNICTERUS//HYPERBILIRUBINEMIA//BILIRUBIN
2 0.0000003638 ALCOHOLISM-CLINICAL AND EXPERIMENTAL RESEARCH//ETHYL GLUCURONIDE//SILIBININ
3 0.0000003556 MUTATION RESEARCH//TOXICOLOGY//CARCINOGENESIS
4 0.0000003393 P GLYCOPROTEIN//MULTIDRUG RESISTANCE//SGLT2 INHIBITOR
5 0.0000003266 HEPATOCYTE GROWTH FACTOR//REGUCALCIN//C MET
6 0.0000002591 HEME OXYGENASE//ACUTE INTERMITTENT PORPHYRIA//PORPHYRIA
7 0.0000002413 PCBS//POLYCHLORINATED BIPHENYLS//CHEMOSPHERE
8 0.0000002347 PRIMARY BILIARY CIRRHOSIS//AUTOIMMUNE HEPATITIS//PRIMARY SCLEROSING CHOLANGITIS
9 0.0000002327 STEROIDS//OSW 1//SQUALAMINE
10 0.0000001931 ACETYLCHOLINESTERASE//SULFUR MUSTARD//ORGANOPHOSPHATES