Class information for:
Level 2: PTP1B//PROTEIN TYROSINE PHOSPHATASE//PRL 3

Basic class information
ID Publications Average number
of references		 Avg. shr. active
ref. in WoS
2255 4236 40.5 78%


Bar chart of Publication_year

Last years might be incomplete

Classes in level above (level 3)


ID, lev.
above		 Publications Label for level above
630 9614 NOONAN SYNDROME//COSTELLO SYNDROME//PROTEIN TYROSINE PHOSPHATASE

Classes in level below (level 1)


ID, lev. below Publications Label for level below
1787 2415 PTP1B//PROTEIN TYROSINE PHOSPHATASE//PROTEIN TYROSINE PHOSPHATASE 1B
14901 673 PROSTATIC ACID PHOSPHATASE//SECT UROL SURG//PROSTATIC PHOSPHATASE
20516 395 ACP1//PHOSPHOTYROSINE PROTEIN PHOSPHATASE//LMW PTP
21054 374 TARTRATE RESISTANT ACID PHOSPHATASE//SPECIAL HEMATOL//TARTRATE RESISTANT
25954 220 PRL 3//PHOSPHATASE OF REGENERATING LIVER 3//PRL 1
28974 159 ACYLPHOSPHATASE//ACYLPHOSPHATASE CATALYTIC MECHANISM//ACYLPHOSPHATASE MUTANT

Terms with highest relevance score


Rank Term Type of term Relevance score
(tfidf)		 Class's shr.
of term's tot.
occurrences		 Shr. of publ.
in class containing
term		 Num. of
publ. in
class
1 PTP1B Author keyword 133 58% 4% 152
2 PROTEIN TYROSINE PHOSPHATASE Author keyword 127 35% 7% 295
3 PRL 3 Author keyword 116 88% 1% 56
4 ACP1 Author keyword 64 79% 1% 41
5 PROTEIN TYROSINE PHOSPHATASE 1B Author keyword 57 49% 2% 84
6 PTPIP51 Author keyword 45 94% 0% 16
7 TCPTP Author keyword 41 85% 1% 22
8 ACYLPHOSPHATASE Author keyword 40 70% 1% 33
9 PROTEIN TYROSINE PHOSPHATASES Author keyword 37 39% 2% 74
10 PRL 1 Author keyword 34 93% 0% 13

Web of Science journal categories

Author Key Words


Rank Web of Science journal category Relevance score
(tfidf)		 Class's shr.
of term's tot.
occurrences		 Shr. of publ.
in class containing
term		 Num. of
publ. in
class		 LCSH search Wikipedia search
1 PTP1B 133 58% 4% 152 Search PTP1B Search PTP1B
2 PROTEIN TYROSINE PHOSPHATASE 127 35% 7% 295 Search PROTEIN+TYROSINE+PHOSPHATASE Search PROTEIN+TYROSINE+PHOSPHATASE
3 PRL 3 116 88% 1% 56 Search PRL+3 Search PRL+3
4 ACP1 64 79% 1% 41 Search ACP1 Search ACP1
5 PROTEIN TYROSINE PHOSPHATASE 1B 57 49% 2% 84 Search PROTEIN+TYROSINE+PHOSPHATASE+1B Search PROTEIN+TYROSINE+PHOSPHATASE+1B
6 PTPIP51 45 94% 0% 16 Search PTPIP51 Search PTPIP51
7 TCPTP 41 85% 1% 22 Search TCPTP Search TCPTP
8 ACYLPHOSPHATASE 40 70% 1% 33 Search ACYLPHOSPHATASE Search ACYLPHOSPHATASE
9 PROTEIN TYROSINE PHOSPHATASES 37 39% 2% 74 Search PROTEIN+TYROSINE+PHOSPHATASES Search PROTEIN+TYROSINE+PHOSPHATASES
10 PRL 1 34 93% 0% 13 Search PRL+1 Search PRL+1

Key Words Plus


Rank Web of Science journal category Relevance score
(tfidf)		 Class's shr.
of term's tot.
occurrences		 Shr. of publ.
in class containing
term		 Num. of
publ. in
class
1 PTP1B 105 62% 3% 109
2 1B 88 34% 5% 214
3 1B INHIBITORS 87 88% 1% 42
4 CRYP ALPHA 81 96% 1% 25
5 PTP 1B INHIBITORS 79 94% 1% 29
6 SUBSTRATE TRAPPING MUTANTS 73 89% 1% 33
7 DEP 1 70 89% 1% 32
8 REGENERATING LIVER 3 69 96% 1% 22
9 PRL 3 PHOSPHATASE 69 93% 1% 26
10 ACP1 62 90% 1% 27

Journals

Reviews


Title Publ. year Cit. Active references % act. ref.
to same field
Inside the human cancer tyrosine phosphatome 2011 133 182 58%
PTP1B as a drug target: recent developments in PTP1B inhibitor discovery 2007 238 69 78%
PTP1B and TCPTP - nonredundant phosphatases in insulin signaling and glucose homeostasis 2013 33 132 66%
Protein tyrosine phosphatases: from genes, to function, to disease 2006 618 126 33%
Protein tyrosine phosphatases - from housekeeping enzymes to master regulators of signal transduction 2013 55 219 37%
Protein tyrosine phosphatases in the human genome 2004 929 69 26%
PTP1B: a double agent in metabolism and oncogenesis 2010 74 85 73%
Small molecule tools for functional interrogation of protein tyrosine phosphatases 2013 33 125 50%
Novel protein tyrosine phosphatase 1B inhibitors: interaction requirements for improved intracellular efficacy in type 2 diabetes mellitus and obesity control 2011 46 42 76%
Protein-tyrosine phosphatases and cancer 2006 283 154 51%

Address terms


Rank Address term Relevance score
(tfidf)		 Class's shr.
of term's tot.
occurrences		 Shr. of publ.
in class containing
term		 Num. of
publ. in
class
1 SPECIAL HEMATOL 14 51% 0.5% 20
2 BIOPATHOL IMAGING DIAGNOST 13 39% 0.6% 27
3 EDMOND H FI ER SIGNAL TRANSDUCT 9 38% 0.5% 20
4 BIOPATHOL HUMAN POPULAT ENVIRONM PATHOL 9 67% 0.2% 8
5 SECT UROL SURG 5 35% 0.3% 12
6 MEDCHEM 1 5 63% 0.1% 5
7 47R 4 67% 0.1% 4
8 MED C6 4 67% 0.1% 4
9 PREVENT SOCIAL PEDIAT 4 38% 0.2% 8
10 CHAIR PREVENT SOCIAL PEDIAT 3 45% 0.1% 5

Related classes at same level (level 2)


Rank Relatedness score Related classes
1 0.0000028907 NOONAN SYNDROME//COSTELLO SYNDROME//THROMBOSPONDIN 1
2 0.0000013760 MIDKINE//PLEIOTROPHIN//HB GAM
3 0.0000012659 COFFIN LOWRY SYNDROME//ERK5//JNK
4 0.0000010237 FOCAL ADHESION KINASE//INTEGRIN LINKED KINASE//FAK
5 0.0000009658 CANTHARIDIN//NORCANTHARIDIN//CIP2A
6 0.0000009475 X LINKED AGAMMAGLOBULINEMIA//BRUTONS TYROSINE KINASE//BTK
7 0.0000009188 N PHOSPHORYL AMINO ACID//BIOORGAN PHOSPHORUS CHEM//SERYL HISTIDINE DIPEPTIDE
8 0.0000008031 VITAMIN K//PHYLLOQUINONE//VITAMIN K2
9 0.0000007377 TENASCIN C//TENASCIN//POLYSIALIC ACID
10 0.0000006404 CHRONIC MYELOID LEUKEMIA//IMATINIB//BCR ABL