Class information for:
Level 1: METACHROMATIC LEUKODYSTROPHY//ARYLSULFATASE A//MULTIPLE SULFATASE DEFICIENCY

Basic class information
Class id #P Avg. number of
references		 Database coverage
of references
11213 999 28.6 56%


Bar chart of Publication_year

Last years might be incomplete

Hierarchy of classes
The table includes all classes above and classes immediately below the current class.


Cluster id Level Cluster label #P
0 4 BIOCHEMISTRY & MOLECULAR BIOLOGY//CELL BIOLOGY//ONCOLOGY 4064930
551 3       FABRY DISEASE//GAUCHER DISEASE//LYSOSOMAL STORAGE DISEASE 18099
491 2             GAUCHER DISEASE//LYSOSOMAL STORAGE DISEASE//MUCOPOLYSACCHARIDOSIS 15457
11213 1                   METACHROMATIC LEUKODYSTROPHY//ARYLSULFATASE A//MULTIPLE SULFATASE DEFICIENCY 999

Terms with highest relevance score


rank Term termType Chi square Shr. of publ. in
class containing
term		 Class's shr. of
term's tot. occurrences		 #P with
term in
class
1 METACHROMATIC LEUKODYSTROPHY authKW 4877536 19% 83% 192
2 ARYLSULFATASE A authKW 2768958 11% 82% 111
3 MULTIPLE SULFATASE DEFICIENCY authKW 702981 2% 100% 23
4 PSEUDODEFICIENCY authKW 547887 2% 81% 22
5 ARYLSULFATASE A PSEUDODEFICIENCY authKW 303840 1% 76% 13
6 ARYLSULPHATASE A authKW 254700 1% 83% 10
7 SUMF1 authKW 254700 1% 83% 10
8 ARYLSULFATASE authKW 233636 3% 26% 29
9 ARYLSULFATASE A DEFICIENCY authKW 213951 1% 100% 7
10 ARYLSULFATASE B authKW 176640 2% 34% 17

Web of Science journal categories


Rank Term Chi square Shr. of publ. in
class containing
term		 Class's shr. of
term's tot. occurrences		 #P with
term in
class
1 Genetics & Heredity 2652 22% 0% 222
2 Clinical Neurology 1195 16% 0% 162
3 Biochemistry & Molecular Biology 1045 30% 0% 295
4 Medicine, Research & Experimental 621 10% 0% 103
5 Pediatrics 461 8% 0% 83
6 Medical Laboratory Technology 363 3% 0% 34
7 Neurosciences 161 10% 0% 99
8 Biophysics 135 5% 0% 53
9 Biotechnology & Applied Microbiology 85 5% 0% 54
10 Endocrinology & Metabolism 70 5% 0% 45

Address terms


Rank Term Chi square Shr. of publ. in
class containing
term		 Class's shr. of
term's tot. occurrences		 #P with
term in
class
1 BIOCHEM ABT 2 106278 2% 17% 20
2 CHILD NEUROL DIS UNIT 40751 0% 67% 2
3 BIOCHEM MOL ZELLBIOL 31861 1% 8% 13
4 ADDENBROOKES CAMBRIDGE UNIV HOSP 30564 0% 100% 1
5 ASSOC RECH NEUROCHIM 30564 0% 100% 1
6 BIOL FUNCTAREA FISIOL 30564 0% 100% 1
7 BIOPROMOENSAIA 30564 0% 100% 1
8 BIOSCI BIOTECHNOL BIOSCI 30564 0% 100% 1
9 CHILDHOOD WHITE MATTER DISORDERS NEUROSCI C 30564 0% 100% 1
10 CHILDREN WHITE MATTER DISORDERS 30564 0% 100% 1

Journals


Rank Term Chi square Shr. of publ. in
class containing
term		 Class's shr. of
term's tot. occurrences		 #P with
term in
class
1 JOURNAL OF INHERITED METABOLIC DISEASE 4184 3% 1% 25
2 HUMAN GENETICS 3187 3% 0% 29
3 REVUE ROUMAINE DE BIOCHIMIE 2504 1% 2% 5
4 HUMAN MUTATION 1946 2% 0% 16
5 MOLECULAR GENETICS AND METABOLISM 1897 1% 0% 14
6 NEUROPEDIATRICS 1804 1% 1% 11
7 DEVELOPMENTAL NEUROSCIENCE 1576 1% 1% 9
8 CLINICAL GENETICS 1512 2% 0% 16
9 HUMAN GENE THERAPY CLINICAL DEVELOPMENT 1505 0% 2% 2
10 MOLECULAR AND CHEMICAL NEUROPATHOLOGY 1446 1% 1% 5

Author Key Words


Rank Term Chi square Shr. of publ. in
class containing
term		 Class's shr. of
term's tot. occurrences		 #P with
term in
class		 LCSH search Wikipedia search
1 METACHROMATIC LEUKODYSTROPHY 4877536 19% 83% 192 Search METACHROMATIC+LEUKODYSTROPHY Search METACHROMATIC+LEUKODYSTROPHY
2 ARYLSULFATASE A 2768958 11% 82% 111 Search ARYLSULFATASE+A Search ARYLSULFATASE+A
3 MULTIPLE SULFATASE DEFICIENCY 702981 2% 100% 23 Search MULTIPLE+SULFATASE+DEFICIENCY Search MULTIPLE+SULFATASE+DEFICIENCY
4 PSEUDODEFICIENCY 547887 2% 81% 22 Search PSEUDODEFICIENCY Search PSEUDODEFICIENCY
5 ARYLSULFATASE A PSEUDODEFICIENCY 303840 1% 76% 13 Search ARYLSULFATASE+A+PSEUDODEFICIENCY Search ARYLSULFATASE+A+PSEUDODEFICIENCY
6 ARYLSULPHATASE A 254700 1% 83% 10 Search ARYLSULPHATASE+A Search ARYLSULPHATASE+A
7 SUMF1 254700 1% 83% 10 Search SUMF1 Search SUMF1
8 ARYLSULFATASE 233636 3% 26% 29 Search ARYLSULFATASE Search ARYLSULFATASE
9 ARYLSULFATASE A DEFICIENCY 213951 1% 100% 7 Search ARYLSULFATASE+A+DEFICIENCY Search ARYLSULFATASE+A+DEFICIENCY
10 ARYLSULFATASE B 176640 2% 34% 17 Search ARYLSULFATASE+B Search ARYLSULFATASE+B

Core articles
The table includes core articles in the class. The following variables is taken into account for the relevance score of an article in a cluster c:
(1) Number of references referring to publications in the class.
(2) Share of total number of active references referring to publications in the class.
(3) Age of the article. New articles get higher score than old articles.
(4) Citation rate, normalized to year.


Rank Reference # ref.
in cl.		 Shr. of ref. in
cl.		 Citations
1 CESANI, M , LORIOLI, L , GROSSI, S , AMICO, G , FUMAGALLI, F , SPIGA, I , FILOCAMO, M , BIFFI, A , (2016) MUTATION UPDATE OF ARSA AND PSAP GENES CAUSING METACHROMATIC LEUKODYSTROPHY.HUMAN MUTATION. VOL. 37. ISSUE 1. P. 16 -27 92 81% 1
2 MAHMOOD, A , BERRY, J , WENGER, DA , ESCOLAR, M , SOBEIH, M , RAYMOND, G , EICHLER, FS , (2010) METACHROMATIC LEUKODYSTROPHY: A CASE OF TRIPLETS WITH THE LATE INFANTILE VARIANT AND A SYSTEMATIC REVIEW OF THE LITERATURE.JOURNAL OF CHILD NEUROLOGY. VOL. 25. ISSUE 5. P. 572-580 66 97% 6
3 VIRGENS, MYF , SIEBERT, M , BOCK, H , BURIN, M , GIUGLIANI, R , SARAIVA-PEREIRA, ML , (2015) GENOTYPIC CHARACTERIZATION OF BRAZILIAN PATIENTS WITH INFANTILE AND JUVENILE FORMS OF METACHROMATIC LEUKODYSTROPHY.GENE. VOL. 568. ISSUE 1. P. 69 -75 43 91% 1
4 SCHLOTAWA, L , ENNEMANN, EC , RADHAKRISHNAN, K , SCHMIDT, B , CHAKRAPANI, A , CHRISTEN, HJ , MOSER, H , STEINMANN, B , DIERKS, T , GARTNER, J , (2011) SUMF1 MUTATIONS AFFECTING STABILITY AND ACTIVITY OF FORMYLGLYCINE GENERATING ENZYME PREDICT CLINICAL OUTCOME IN MULTIPLE SULFATASE DEFICIENCY.EUROPEAN JOURNAL OF HUMAN GENETICS. VOL. 19. ISSUE 3. P. 253 -261 33 83% 16
5 BATZIOS, SP , ZAFEIRIOU, DI , (2012) DEVELOPING TREATMENT OPTIONS FOR METACHROMATIC LEUKODYSTROPHY.MOLECULAR GENETICS AND METABOLISM. VOL. 105. ISSUE 1. P. 56 -63 52 50% 18
6 VAN RAPPARD, DF , BOELENS, JJ , WOLF, NI , (2015) METACHROMATIC LEUKODYSTROPHY: DISEASE SPECTRUM AND APPROACHES FOR TREATMENT.BEST PRACTICE & RESEARCH CLINICAL ENDOCRINOLOGY & METABOLISM. VOL. 29. ISSUE 2. P. 261 -273 29 81% 6
7 GIESELMANN, V , KRAGELOH-MANN, I , (2010) METACHROMATIC LEUKODYSTROPHY - AN UPDATE.NEUROPEDIATRICS. VOL. 41. ISSUE 1. P. 1 -6 28 85% 46
8 APPEL, MJ , BERTOZZI, CR , (2015) FORMYLGLYCINE, A POST-TRANSLATIONALLY GENERATED RESIDUE WITH UNIQUE CATALYTIC CAPABILITIES AND BIOTECHNOLOGY APPLICATIONS.ACS CHEMICAL BIOLOGY. VOL. 10. ISSUE 1. P. 72 -84 41 46% 15
9 PATIL, SA , MAEGAWA, GHB , (2013) DEVELOPING THERAPEUTIC APPROACHES FOR METACHROMATIC LEUKODYSTROPHY.DRUG DESIGN DEVELOPMENT AND THERAPY. VOL. 7. ISSUE . P. 729-745 53 42% 14
10 GIESELMANN, V , MATZNER, U , HESS, B , LULLMANN-RAUCH, R , COENEN, R , HARTMANN, D , D'HOOGE, R , DEDEYN, P , NAGELS, G , (1998) METACHROMATIC LEUKODYSTROPHY: MOLECULAR GENETICS AND AN ANIMAL MODEL.JOURNAL OF INHERITED METABOLIC DISEASE. VOL. 21. ISSUE 5. P. 564 -574 39 89% 27

Classes with closest relation at Level 1


Rank Class id link
1 16795 KRABBE DISEASE//GLOBOID CELL LEUKODYSTROPHY//PSYCHOSINE
2 18342 SULFATIDE//BIOMED ANAL RADIOISOTOPE//SEMINOLIPID
3 17857 PROSAPOSIN//SPHINGOLIPID ACTIVATOR PROTEINS//SAPOSIN
4 12125 STEROID SULFATASE//X LINKED ICHTHYOSIS//ESTRONE SULFATASE
5 1052 MUCOPOLYSACCHARIDOSIS//MUCOPOLYSACCHARIDOSES//HUNTER SYNDROME
6 12163 SANDHOFF DISEASE//GM2 GANGLIOSIDOSIS//TAY SACHS DISEASE
7 12781 ALEXANDER DISEASE//LEUKODYSTROPHY//ROSENTHAL FIBERS
8 7726 MANNOSE 6 PHOSPHATE//MANNOSE 6 PHOSPHATE RECEPTOR//I CELL DISEASE
9 29415 LYSOSOMAL EXOGLYCOSIDASES//GEN SURG ENDOCRINOL 1//N ACETYL BETA HEXOSAMINIDASE
10 36178 KURLOFF CELL//AFFINOBLOTTING//ANIM HLTH HOSP

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