Class information for:
Level 1: SEVERE COMBINED IMMUNODEFICIENCY//OMENN SYNDROME//PRIMARY IMMUNODEFICIENCY

Basic class information
Class id #P Avg. number of
references		 Database coverage
of references
12297 916 35.6 78%


Bar chart of Publication_year

Last years might be incomplete

Hierarchy of classes
The table includes all classes above and classes immediately below the current class.


Cluster id Level Cluster label #P
6 4 GASTROENTEROLOGY & HEPATOLOGY//ONCOLOGY//SURGERY 1371034
530 3       SPLENECTOMY//COMMON VARIABLE IMMUNODEFICIENCY//IMMUNE THROMBOCYTOPENIA 19898
1704 2             COMMON VARIABLE IMMUNODEFICIENCY//PRIMARY IMMUNODEFICIENCY//INTRAVENOUS IMMUNOGLOBULIN 6726
12297 1                   SEVERE COMBINED IMMUNODEFICIENCY//OMENN SYNDROME//PRIMARY IMMUNODEFICIENCY 916

Terms with highest relevance score


rank Term termType Chi square Shr. of publ. in
class containing
term		 Class's shr. of
term's tot. occurrences		 #P with
term in
class
1 SEVERE COMBINED IMMUNODEFICIENCY authKW 2044849 16% 43% 144
2 OMENN SYNDROME authKW 1547155 6% 81% 57
3 PRIMARY IMMUNODEFICIENCY authKW 431714 10% 14% 94
4 SEVERE COMBINED IMMUNODEFICIENCY SCID authKW 349987 2% 50% 21
5 T CELL LYMPHOPENIA authKW 331374 1% 76% 13
6 SCID authKW 313912 7% 15% 61
7 X SCID authKW 249990 2% 50% 15
8 SEVERE COMBINED IMMUNE DEFICIENCY authKW 245439 2% 41% 18
9 JEFFREY MODELL DIAGNOST PRIMARY IMMUNOD address 207691 1% 69% 9
10 RAG DEFICIENCY authKW 200004 1% 100% 6

Web of Science journal categories


Rank Term Chi square Shr. of publ. in
class containing
term		 Class's shr. of
term's tot. occurrences		 #P with
term in
class
1 Immunology 9319 48% 0% 442
2 Allergy 7806 14% 0% 126
3 Hematology 3887 20% 0% 186
4 Pediatrics 2098 17% 0% 157
5 Transplantation 1745 9% 0% 86
6 Medicine, Research & Experimental 185 6% 0% 59
7 Genetics & Heredity 140 7% 0% 60
8 Pathology 138 4% 0% 38
9 Medicine, General & Internal 137 7% 0% 67
10 Oncology 95 7% 0% 68

Address terms


Rank Term Chi square Shr. of publ. in
class containing
term		 Class's shr. of
term's tot. occurrences		 #P with
term in
class
1 JEFFREY MODELL DIAGNOST PRIMARY IMMUNOD 207691 1% 69% 9
2 PEDIAT ALLERGY IMMUNOL BLOOD MARROW TRANS 138890 1% 83% 5
3 ALLERGY IMMUNOL BLOOD MARROW TRANSPLANTAT 104165 1% 63% 5
4 CLIN IMMUNOL TRANSFUS MED MED 100002 0% 100% 3
5 PEDIAT IMMUNOL SERV 77770 1% 33% 7
6 IMMUNODEFICIENCY LEIPZIG IDCL 75000 0% 75% 3
7 PEDIAT CLINTEC 75000 0% 75% 3
8 HELIOS KLINIKUM KREFELD HOSP 66668 0% 100% 2
9 JEFFERY MODELL FDN JMF 66668 0% 100% 2
10 NEWBORN SCREENING TRANSLAT NETWORK 66668 0% 100% 2

Journals


Rank Term Chi square Shr. of publ. in
class containing
term		 Class's shr. of
term's tot. occurrences		 #P with
term in
class
1 JOURNAL OF CLINICAL IMMUNOLOGY 31765 5% 2% 49
2 JOURNAL OF ALLERGY AND CLINICAL IMMUNOLOGY 14107 7% 1% 67
3 BONE MARROW TRANSPLANTATION 7293 5% 1% 44
4 IMMUNOLOGY AND ALLERGY CLINICS OF NORTH AMERICA 7118 2% 1% 17
5 IMMUNOLOGIC RESEARCH 5597 2% 1% 17
6 CLINICAL IMMUNOLOGY 5472 2% 1% 21
7 CLINICAL IMMUNOLOGY AND IMMUNOPATHOLOGY 5210 3% 1% 23
8 CURRENT OPINION IN ALLERGY AND CLINICAL IMMUNOLOGY 4596 1% 1% 12
9 BLOOD 3088 6% 0% 57
10 PEDIATRIC TRANSPLANTATION 2829 2% 1% 14

Author Key Words


Rank Term Chi square Shr. of publ. in
class containing
term		 Class's shr. of
term's tot. occurrences		 #P with
term in
class		 LCSH search Wikipedia search
1 SEVERE COMBINED IMMUNODEFICIENCY 2044849 16% 43% 144 Search SEVERE+COMBINED+IMMUNODEFICIENCY Search SEVERE+COMBINED+IMMUNODEFICIENCY
2 OMENN SYNDROME 1547155 6% 81% 57 Search OMENN+SYNDROME Search OMENN+SYNDROME
3 PRIMARY IMMUNODEFICIENCY 431714 10% 14% 94 Search PRIMARY+IMMUNODEFICIENCY Search PRIMARY+IMMUNODEFICIENCY
4 SEVERE COMBINED IMMUNODEFICIENCY SCID 349987 2% 50% 21 Search SEVERE+COMBINED+IMMUNODEFICIENCY+SCID Search SEVERE+COMBINED+IMMUNODEFICIENCY+SCID
5 T CELL LYMPHOPENIA 331374 1% 76% 13 Search T+CELL+LYMPHOPENIA Search T+CELL+LYMPHOPENIA
6 SCID 313912 7% 15% 61 Search SCID Search SCID
7 X SCID 249990 2% 50% 15 Search X+SCID Search X+SCID
8 SEVERE COMBINED IMMUNE DEFICIENCY 245439 2% 41% 18 Search SEVERE+COMBINED+IMMUNE+DEFICIENCY Search SEVERE+COMBINED+IMMUNE+DEFICIENCY
9 RAG DEFICIENCY 200004 1% 100% 6 Search RAG+DEFICIENCY Search RAG+DEFICIENCY
10 T CELL RECEPTOR EXCISION CIRCLES 164084 2% 31% 16 Search T+CELL+RECEPTOR+EXCISION+CIRCLES Search T+CELL+RECEPTOR+EXCISION+CIRCLES

Core articles
The table includes core articles in the class. The following variables is taken into account for the relevance score of an article in a cluster c:
(1) Number of references referring to publications in the class.
(2) Share of total number of active references referring to publications in the class.
(3) Age of the article. New articles get higher score than old articles.
(4) Citation rate, normalized to year.


Rank Reference # ref.
in cl.		 Shr. of ref. in
cl.		 Citations
1 KTUAN, A , PUCK, JM , (2015) HISTORY AND CURRENT STATUS OF NEWBORN SCREENING FOR SEVERE COMBINED IMMUNODEFICIENCY.SEMINARS IN PERINATOLOGY. VOL. 39. ISSUE 3. P. 194 -205 52 64% 0
2 PAI, SY , LOGAN, BR , GRIFFITH, LM , BUCKLEY, RH , PARROTT, RE , DVORAK, CC , KAPOOR, N , HANSON, IC , FILIPOVICH, AH , JYONOUCHI, S , ET AL (2014) TRANSPLANTATION OUTCOMES FOR SEVERE COMBINED IMMUNODEFICIENCY, 2000-2009.NEW ENGLAND JOURNAL OF MEDICINE. VOL. 371. ISSUE 5. P. 434 -446 26 84% 53
3 BUCKLEY, RH , (2011) TRANSPLANTATION OF HEMATOPOIETIC STEM CELLS IN HUMAN SEVERE COMBINED IMMUNODEFICIENCY: LONGTERM OUTCOMES.IMMUNOLOGIC RESEARCH. VOL. 49. ISSUE 1-3. P. 25 -43 40 69% 55
4 GASPAR, HB , HAMMARSTROM, L , MAHLAOUI, N , BORTE, M , BORTE, S , (2014) THE CASE FOR MANDATORY NEWBORN SCREENING FOR SEVERE COMBINED IMMUNODEFICIENCY (SCID).JOURNAL OF CLINICAL IMMUNOLOGY. VOL. 34. ISSUE 4. P. 393-397 31 79% 19
5 NOTARANGELO, LD , KIM, MS , WALTER, JE , LEE, YN , (2016) HUMAN RAG MUTATIONS: BIOCHEMISTRY AND CLINICAL IMPLICATIONS.NATURE REVIEWS IMMUNOLOGY. VOL. 16. ISSUE 4. P. 234 -246 42 43% 6
6 HADDAD, E , LEROY, S , BUCKLEY, RH , (2013) B-CELL RECONSTITUTION FOR SCID: SHOULD A CONDITIONING REGIMEN BE USED IN SCID TREATMENT?.JOURNAL OF ALLERGY AND CLINICAL IMMUNOLOGY. VOL. 131. ISSUE 4. P. 994-1000 25 89% 27
7 VAN DER SPEK, J , GROENWOLD, RHH , VAN DER BURG, M , VAN MONTFRANS, JM , (2015) TREC BASED NEWBORN SCREENING FOR SEVERE COMBINED IMMUNODEFICIENCY DISEASE: A SYSTEMATIC REVIEW.JOURNAL OF CLINICAL IMMUNOLOGY. VOL. 35. ISSUE 4. P. 416 -430 27 79% 8
8 CUVELIER, GDE , SCHULTZ, KR , DAVIS, J , HIRSCHFELD, AF , JUNKER, AK , TAN, R , TURVEY, SE , (2009) OPTIMIZING OUTCOMES OF HEMATOPOIETIC STEM CELL TRANSPLANTATION FOR SEVERE COMBINED IMMUNODEFICIENCY.CLINICAL IMMUNOLOGY. VOL. 131. ISSUE 2. P. 179-188 32 74% 10
9 FISCHER, A , NOTARANGELO, LD , NEVEN, B , CAVAZZANA, M , PUCK, JM , (2015) SEVERE COMBINED IMMUNODEFICIENCIES AND RELATED DISORDERS.NATURE REVIEWS DISEASE PRIMERS. VOL. 1. ISSUE . P. - 54 38% 1
10 DVORAK, CC , COWAN, MJ , LOGAN, BR , NOTARANGELO, LD , GRIFFITH, LM , PUCK, JM , KOHN, DB , SHEARER, WT , O'REILLY, RJ , FLEISHER, TA , ET AL (2013) THE NATURAL HISTORY OF CHILDREN WITH SEVERE COMBINED IMMUNODEFICIENCY: BASELINE FEATURES OF THE FIRST FIFTY PATIENTS OF THE PRIMARY IMMUNE DEFICIENCY TREATMENT CONSORTIUM PROSPECTIVE STUDY 6901.JOURNAL OF CLINICAL IMMUNOLOGY. VOL. 33. ISSUE 7. P. 1156-1164 24 80% 15

Classes with closest relation at Level 1


Rank Class id link
1 3006 COMMON VARIABLE IMMUNODEFICIENCY//IGA DEFICIENCY//CVID
2 11252 WISKOTT ALDRICH SYNDROME//X LINKED THROMBOCYTOPENIA//WISKOTT ALDRICH SYNDROME PROTEIN
3 15463 STEM CELL TRANSPLANTAT PROGRAMME//BONE MARROW TRANSPLANTATION//CD6 ANTIBODY
4 20465 HYPER IGE SYNDROME//JOBS SYNDROME//HYPERIMMUNOGLOBULIN E SYNDROME
5 13676 TOFACITINIB//JAK3//JANUS KINASE
6 5370 ADENOSINE DEAMINASE//PURINE NUCLEOSIDE PHOSPHORYLASE DEFICIENCY//CECR1
7 2246 LENTIVIRAL VECTOR//EXPT HEMATOL//RETROVIRAL VECTOR
8 13755 HUMAN GENET INFECT DIS//MENDELIAN SUSCEPTIBILITY TO MYCOBACTERIAL DISEASE//PEDIAT IMMUNOL HEMATOL UNIT
9 16216 IN UTERO TRANSPLANTATION//FETAL GENE THERAPY//CHILDRENS SURG SCI
10 10888 IMMUNE RECONSTITUTION//TREC//LYMPHOCYTE RECOVERY

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