Class information for:
Level 1: HYPERTONICITY//NFAT5//ORGANIC OSMOLYTES

Basic class information
Class id #P Avg. number of
references		 Database coverage
of references
12936 871 39.9 83%


Bar chart of Publication_year

Last years might be incomplete

Hierarchy of classes
The table includes all classes above and classes immediately below the current class.


Cluster id Level Cluster label #P
0 4 BIOCHEMISTRY & MOLECULAR BIOLOGY//CELL BIOLOGY//ONCOLOGY 4064930
222 3       MYOTONIC DYSTROPHY//ALDOSTERONE//PHYSIOLOGY 49798
1894 2             CYSTINURIA//REGULATORY VOLUME DECREASE//CELL VOLUME REGULATION 5956
12936 1                   HYPERTONICITY//NFAT5//ORGANIC OSMOLYTES 871

Terms with highest relevance score


rank Term termType Chi square Shr. of publ. in
class containing
term		 Class's shr. of
term's tot. occurrences		 #P with
term in
class
1 HYPERTONICITY authKW 884886 9% 32% 78
2 NFAT5 authKW 858860 4% 70% 35
3 ORGANIC OSMOLYTES authKW 813769 6% 44% 53
4 TONEBP authKW 709878 3% 75% 27
5 GLYCEROPHOSPHORYLCHOLINE authKW 396387 2% 54% 21
6 NA MYO INOSITOL COTRANSPORTER authKW 292133 1% 83% 10
7 KIDNEY ELE OLYTE METAB address 285241 6% 17% 49
8 SODIUM MYO INOSITOL COTRANSPORTER authKW 283955 1% 90% 9
9 OSMOLYTES authKW 259754 8% 10% 71
10 TONICITY RESPONSIVE ENHANCER BINDING PROTEIN authKW 258139 1% 82% 9

Web of Science journal categories


Rank Term Chi square Shr. of publ. in
class containing
term		 Class's shr. of
term's tot. occurrences		 #P with
term in
class
1 Physiology 11015 39% 0% 337
2 Urology & Nephrology 4603 22% 0% 188
3 Biochemistry & Molecular Biology 892 29% 0% 255
4 Cell Biology 847 17% 0% 152
5 Biophysics 218 7% 0% 59
6 Zoology 73 4% 0% 34
7 Medicine, Research & Experimental 67 4% 0% 39
8 Ophthalmology 65 3% 0% 26
9 Neurosciences 42 7% 0% 59
10 Reproductive Biology 7 1% 0% 8

Address terms


Rank Term Chi square Shr. of publ. in
class containing
term		 Class's shr. of
term's tot. occurrences		 #P with
term in
class
1 KIDNEY ELE OLYTE METAB 285241 6% 17% 49
2 ARIZONA HLTH SCI MED SECT RENAL DIS 70113 0% 100% 2
3 PATHOLRENAL PATHOL 70113 0% 100% 2
4 RENAL CELLULAR MOL BIOL SECT 70113 0% 100% 2
5 SEZ PATOL MOL IMMUNOL 50472 1% 24% 6
6 BIOL SCI 4004 35056 0% 100% 1
7 CELLULAR INTEGRAT 35056 0% 100% 1
8 CIENCIAS QUIMICASY FARMACEUT 35056 0% 100% 1
9 CIUDAD AUTONOMA 35056 0% 100% 1
10 CLIN PHARMCOL PHARMACOGENOM 35056 0% 100% 1

Journals


Rank Term Chi square Shr. of publ. in
class containing
term		 Class's shr. of
term's tot. occurrences		 #P with
term in
class
1 AMERICAN JOURNAL OF PHYSIOLOGY-RENAL PHYSIOLOGY 37726 10% 1% 84
2 INTERNATIONAL CONGRESS SERIES 35050 0% 25% 4
3 AMERICAN JOURNAL OF PHYSIOLOGY-CELL PHYSIOLOGY 8575 5% 1% 42
4 PFLUGERS ARCHIV-EUROPEAN JOURNAL OF PHYSIOLOGY 6105 4% 0% 38
5 AMERICAN JOURNAL OF PHYSIOLOGY 5226 7% 0% 61
6 KIDNEY INTERNATIONAL 4219 5% 0% 42
7 RENAL PHYSIOLOGY AND BIOCHEMISTRY 2543 1% 1% 6
8 JOURNAL OF THE AMERICAN SOCIETY OF NEPHROLOGY 1538 2% 0% 18
9 JAPANESE JOURNAL OF NEPHROLOGY 897 0% 3% 1
10 FRONTIERS IN PHYSIOLOGY 867 1% 0% 8

Author Key Words


Rank Term Chi square Shr. of publ. in
class containing
term		 Class's shr. of
term's tot. occurrences		 #P with
term in
class		 LCSH search Wikipedia search
1 HYPERTONICITY 884886 9% 32% 78 Search HYPERTONICITY Search HYPERTONICITY
2 NFAT5 858860 4% 70% 35 Search NFAT5 Search NFAT5
3 ORGANIC OSMOLYTES 813769 6% 44% 53 Search ORGANIC+OSMOLYTES Search ORGANIC+OSMOLYTES
4 TONEBP 709878 3% 75% 27 Search TONEBP Search TONEBP
5 GLYCEROPHOSPHORYLCHOLINE 396387 2% 54% 21 Search GLYCEROPHOSPHORYLCHOLINE Search GLYCEROPHOSPHORYLCHOLINE
6 NA MYO INOSITOL COTRANSPORTER 292133 1% 83% 10 Search NA+MYO+INOSITOL+COTRANSPORTER Search NA+MYO+INOSITOL+COTRANSPORTER
7 SODIUM MYO INOSITOL COTRANSPORTER 283955 1% 90% 9 Search SODIUM+MYO+INOSITOL+COTRANSPORTER Search SODIUM+MYO+INOSITOL+COTRANSPORTER
8 OSMOLYTES 259754 8% 10% 71 Search OSMOLYTES Search OSMOLYTES
9 TONICITY RESPONSIVE ENHANCER BINDING PROTEIN 258139 1% 82% 9 Search TONICITY+RESPONSIVE+ENHANCER+BINDING+PROTEIN Search TONICITY+RESPONSIVE+ENHANCER+BINDING+PROTEIN
10 HYPERTONIC STRESS 250377 2% 36% 20 Search HYPERTONIC+STRESS Search HYPERTONIC+STRESS

Core articles
The table includes core articles in the class. The following variables is taken into account for the relevance score of an article in a cluster c:
(1) Number of references referring to publications in the class.
(2) Share of total number of active references referring to publications in the class.
(3) Age of the article. New articles get higher score than old articles.
(4) Citation rate, normalized to year.


Rank Reference # ref. in
cl.		 Shr. of ref. in
cl.		 Citations
1 BURG, MB , FERRARIS, JD , DMITRIEVA, NI , (2007) CELLULAR RESPONSE TO HYPEROSMOTIC STRESSES.PHYSIOLOGICAL REVIEWS. VOL. 87. ISSUE 4. P. 1441-1474 153 47% 280
2 BECK, FX , NEUHOFER, W , (2006) CELL VOLUME REGULATION IN THE RENAL PAPILLA.MECHANISMS AND SIGNIFICANCE OF CELL VOLUME REGULATION. VOL. 152. ISSUE . P. 181-197 92 77% 7
3 NEUHOFER, W , BECK, FX , (2005) RESPONSE OF RENAL MEDULLARY CELLS TO OSMOTIC STRESS.CELLULAR STRESS RESPONSES IN RENAL DISEASES. VOL. 148. ISSUE . P. 21 -34 78 86% 20
4 NEUHOFER, W , BECK, FX , (2005) CELL SURVIVAL IN THE HOSTILE ENVIRONMENT OF THE RENAL MEDULLA.ANNUAL REVIEW OF PHYSIOLOGY. VOL. 67. ISSUE . P. 531 -555 102 59% 70
5 GRUNEWALDT, RW , KINNE, RKH , (1999) OSMOREGULATION IN THE MAMMALIAN KIDNEY: THE ROLE OF ORGANIC OSMOLYTES.JOURNAL OF EXPERIMENTAL ZOOLOGY. VOL. 283. ISSUE 7. P. 708-724 102 73% 15
6 BECK, FX , BURGER-KENTISCHER, A , MULLER, E , (1998) CELLULAR RESPONSE TO OSMOTIC STRESS IN THE RENAL MEDULLA.PFLUGERS ARCHIV-EUROPEAN JOURNAL OF PHYSIOLOGY. VOL. 436. ISSUE 6. P. 814-827 99 69% 70
7 BECK, FX , GUDER, WG , SCHMOLKE, M , (1998) CELLULAR OSMOREGULATION IN KIDNEY MEDULLA.CELL VOLUME REGULATION. VOL. 123. ISSUE . P. 169 -184 74 72% 6
8 BISSONNETTE, P , LAHJOUJI, K , COADY, MJ , LAPOINTE, JY , (2008) EFFECTS OF HYPEROSMOLARITY ON THE NA+-MYO-INOSITOL COTRANSPORTER SMIT2 STABLY TRANSFECTED IN THE MADIN-DARBY CANINE KIDNEY CELL LINE.AMERICAN JOURNAL OF PHYSIOLOGY-CELL PHYSIOLOGY. VOL. 295. ISSUE 3. P. C791-C799 43 84% 10
9 JEON, US , KIM, JA , SHEEN, MR , KWON, HM , (2006) HOW TONICITY REGULATES GENES: STORY OF TONEBP TRANSCRIPTIONAL ACTIVATOR.ACTA PHYSIOLOGICA. VOL. 187. ISSUE 1-2. P. 241-247 40 83% 68
10 KEMPSON, SA , ZHOU, Y , DANBOLT, NC , (2014) THE BETAINE/GABA TRANSPORTER AND BETAINE: ROLES IN BRAIN, KIDNEY, AND LIVER.FRONTIERS IN PHYSIOLOGY. VOL. 5. ISSUE . P. - 70 38% 7

Classes with closest relation at Level 1


Rank Class id link
1 20634 CELL VOLUME//INTRACELLULAR WATER SPACE//ANISOTONICITY
2 34012 JR GRP 2//SODIUM RESERVOIRS//NA STORAGE
3 3052 REGULATORY VOLUME DECREASE//VOLUME REGULATION//CELL VOLUME REGULATION
4 20818 INOSITOL MONOPHOSPHATASE//MYO INOSITOL MONOPHOSPHATASE//INOSITOL
5 2952 ALDOSE REDUCTASE//ALDOSE REDUCTASE INHIBITOR//AKR1B10
6 9378 OSMOLYTES//PREFERENTIAL INTERACTIONS//PREFERENTIAL HYDRATION
7 34013 GLYCEROPHOSPHOINOSITOL//GLYCEROPHOSPHODIESTER PHOSPHODIESTERASE//GDE DOMAIN
8 12192 SYSTEM A//SYSTEM N//ASC SYSTEM
9 24173 PHOSPHOLEMMAN//FXYD PROTEINS//FXYD
10 12114 URINE CONCENTRATING MECHANISM//UREA TRANSPORT//UREA TRANSPORTER

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