Class information for:
Level 1: GLUCOLIPOTOXICITY//LIPOTOXICITY//BETA CELL BIOCHEM

Basic class information
Class id #P Avg. number of
references		 Database coverage
of references
13751 815 47.6 89%


Bar chart of Publication_year

Last years might be incomplete

Hierarchy of classes
The table includes all classes above and classes immediately below the current class.


Cluster id Level Cluster label #P
0 4 BIOCHEMISTRY & MOLECULAR BIOLOGY//CELL BIOLOGY//ONCOLOGY 4064930
297 3       DIABETES//ISLET TRANSPLANTATION//BETA CELL 41297
457 2             BETA CELL//INSULIN SECRETION//PANCREATIC ISLETS 16005
13751 1                   GLUCOLIPOTOXICITY//LIPOTOXICITY//BETA CELL BIOCHEM 815

Terms with highest relevance score


rank Term termType Chi square Shr. of publ. in
class containing
term		 Class's shr. of
term's tot. occurrences		 #P with
term in
class
1 GLUCOLIPOTOXICITY authKW 496558 3% 49% 27
2 LIPOTOXICITY authKW 451718 10% 15% 81
3 BETA CELL BIOCHEM address 397776 2% 56% 19
4 PALMITATE authKW 282325 7% 13% 57
5 INSULIN SECRETION authKW 175659 15% 4% 124
6 PANCREATIC BETA CELL authKW 150646 8% 6% 68
7 ARF GAP1 authKW 112396 0% 100% 3
8 LOOSE LIPID PACKING authKW 112396 0% 100% 3
9 VESICULAR BUDDING authKW 112396 0% 100% 3
10 BETA CELL authKW 106958 10% 4% 79

Web of Science journal categories


Rank Term Chi square Shr. of publ. in
class containing
term		 Class's shr. of
term's tot. occurrences		 #P with
term in
class
1 Endocrinology & Metabolism 16158 54% 0% 439
2 Biochemistry & Molecular Biology 406 22% 0% 180
3 Cell Biology 404 13% 0% 107
4 Physiology 319 8% 0% 63
5 Biophysics 144 6% 0% 48
6 Medicine, Research & Experimental 124 6% 0% 47
7 Nutrition & Dietetics 93 3% 0% 28
8 Pharmacology & Pharmacy 21 6% 0% 47
9 Psychology, Biological 8 0% 0% 4
10 Integrative & Complementary Medicine 7 0% 0% 4

Address terms


Rank Term Chi square Shr. of publ. in
class containing
term		 Class's shr. of
term's tot. occurrences		 #P with
term in
class
1 BETA CELL BIOCHEM 397776 2% 56% 19
2 LEEGILYA CANC DIABET 84295 0% 75% 3
3 SERV B4237 74931 0% 100% 2
4 MONTREAL DIABET 74439 2% 11% 18
5 ENDOCRINE PHARMACOL GRP 49952 0% 67% 2
6 SIGNORELLI DIABET 49952 0% 67% 2
7 TRANSPLANTAT ENGN 49952 0% 67% 2
8 MOL NUTR UNIT 48096 2% 7% 19
9 AMBULANZ NATURHEILVERFAHREN 37465 0% 100% 1
10 ATHERSCLEROSE 37465 0% 100% 1

Journals


Rank Term Chi square Shr. of publ. in
class containing
term		 Class's shr. of
term's tot. occurrences		 #P with
term in
class
1 DIABETES 33163 13% 1% 103
2 ISLETS 10447 1% 3% 9
3 DIABETOLOGIA 7553 5% 0% 41
4 AMERICAN JOURNAL OF PHYSIOLOGY-ENDOCRINOLOGY AND METABOLISM 5156 4% 0% 30
5 DIABETES OBESITY & METABOLISM 3805 2% 1% 15
6 METABOLISM-CLINICAL AND EXPERIMENTAL 3283 3% 0% 28
7 ENDOCRINOLOGY 1807 4% 0% 35
8 PEZCOLLER FOUNDATION SYMPOSIA 1174 1% 0% 8
9 CURRENT DIABETES REPORTS 1146 1% 1% 5
10 JOURNAL OF DIABETES RESEARCH 1026 1% 1% 5

Author Key Words


Rank Term Chi square Shr. of publ. in
class containing
term		 Class's shr. of
term's tot. occurrences		 #P with
term in
class		 LCSH search Wikipedia search
1 GLUCOLIPOTOXICITY 496558 3% 49% 27 Search GLUCOLIPOTOXICITY Search GLUCOLIPOTOXICITY
2 LIPOTOXICITY 451718 10% 15% 81 Search LIPOTOXICITY Search LIPOTOXICITY
3 PALMITATE 282325 7% 13% 57 Search PALMITATE Search PALMITATE
4 INSULIN SECRETION 175659 15% 4% 124 Search INSULIN+SECRETION Search INSULIN+SECRETION
5 PANCREATIC BETA CELL 150646 8% 6% 68 Search PANCREATIC+BETA+CELL Search PANCREATIC+BETA+CELL
6 ARF GAP1 112396 0% 100% 3 Search ARF+GAP1 Search ARF+GAP1
7 LOOSE LIPID PACKING 112396 0% 100% 3 Search LOOSE+LIPID+PACKING Search LOOSE+LIPID+PACKING
8 VESICULAR BUDDING 112396 0% 100% 3 Search VESICULAR+BUDDING Search VESICULAR+BUDDING
9 BETA CELL 106958 10% 4% 79 Search BETA+CELL Search BETA+CELL
10 GLUCOTOXICITY 88947 2% 13% 19 Search GLUCOTOXICITY Search GLUCOTOXICITY

Core articles
The table includes core articles in the class. The following variables is taken into account for the relevance score of an article in a cluster c:
(1) Number of references referring to publications in the class.
(2) Share of total number of active references referring to publications in the class.
(3) Age of the article. New articles get higher score than old articles.
(4) Citation rate, normalized to year.


Rank Reference # ref.
in cl.		 Shr. of ref. in
cl.		 Citations
1 POITOUT, V , ROBERTSON, RP , (2008) GLUCOLIPOTOXICITY: FUEL EXCESS AND BETA-CELL DYSFUNCTION.ENDOCRINE REVIEWS. VOL. 29. ISSUE 3. P. 351-366 67 35% 434
2 POITOUT, V , AMYOT, J , SEMACHE, M , ZARROUKI, B , HAGMAN, D , FONTES, G , (2010) GLUCOLIPOTOXICITY OF THE PANCREATIC BETA CELL.BIOCHIMICA ET BIOPHYSICA ACTA-MOLECULAR AND CELL BIOLOGY OF LIPIDS. VOL. 1801. ISSUE 3. P. 289 -298 64 47% 105
3 NEWSHOLME, P , KEANE, D , WELTERS, HJ , MORGAN, NG , (2007) LIFE AND DEATH DECISIONS OF THE PANCREATIC BETA-CELL: THE ROLE OF FATTY ACIDS.CLINICAL SCIENCE. VOL. 112. ISSUE 1-2. P. 27-42 71 49% 59
4 VAN RAALTE, DH , VAN DER ZIJL, NJ , DIAMANT, M , (2010) PANCREATIC STEATOSIS IN HUMANS: CAUSE OR MARKER OF LIPOTOXICITY?.CURRENT OPINION IN CLINICAL NUTRITION AND METABOLIC CARE. VOL. 13. ISSUE 4. P. 478-485 40 63% 31
5 GIACCA, A , XIAO, CT , OPRESCU, AI , CARPENTIER, AC , LEWIS, GF , (2011) LIPID-INDUCED PANCREATIC BETA-CELL DYSFUNCTION: FOCUS ON IN VIVO STUDIES.AMERICAN JOURNAL OF PHYSIOLOGY-ENDOCRINOLOGY AND METABOLISM. VOL. 300. ISSUE 2. P. E255-E262 44 49% 64
6 GOH, TT , MASON, TM , GUPTA, N , SO, A , LAM, TKT , LAM, L , LEWIS, GF , MARI, A , GIACCA, A , (2007) LIPID-INDUCED BETA-CELL DYSFUNCTION IN VIVO IN MODELS OF PROGRESSIVE BETA-CELL FAILURE.AMERICAN JOURNAL OF PHYSIOLOGY-ENDOCRINOLOGY AND METABOLISM. VOL. 292. ISSUE 2. P. E549-E560 34 74% 32
7 FONTES, G , ZARROUKI, B , HAGMAN, DK , LATOUR, MG , SEMACHE, M , ROSKENS, V , MOORE, PC , PRENTKI, M , RHODES, CJ , JETTON, TL , ET AL (2010) GLUCOLIPOTOXICITY AGE-DEPENDENTLY IMPAIRS BETA CELL FUNCTION IN RATS DESPITE A MARKED INCREASE IN BETA CELL MASS.DIABETOLOGIA. VOL. 53. ISSUE 11. P. 2369 -2379 30 60% 38
8 OPRESCU, AI , GIACCA, A , (2007) LIPID-INDUCED BETA-CELL DYSFUNCTION AND OXIDATIVE STRESS.FUTURE LIPIDOLOGY. VOL. 2. ISSUE 4. P. 455 -463 45 48% 1
9 GRILL, V , QVIGSTAD, E , (2000) FATTY ACIDS AND INSULIN SECRETION.BRITISH JOURNAL OF NUTRITION. VOL. 83. ISSUE . P. S79 -S84 26 90% 31
10 CHOI, SE , JUNG, IR , LEE, YJ , LEE, SJ , LEE, JH , KIM, Y , JUN, HS , LEE, KW , PARK, CB , KANG, Y , (2011) STIMULATION OF LIPOGENESIS AS WELL AS FATTY ACID OXIDATION PROTECTS AGAINST PALMITATE-INDUCED INS-1 BETA-CELL DEATH.ENDOCRINOLOGY. VOL. 152. ISSUE 3. P. 816 -827 27 61% 20

Classes with closest relation at Level 1


Rank Class id link
1 8615 BETA CELL MASS//BETA CELL PROLIFERATION//BETA CELL
2 15285 GPR40//GPR120//GPR119
3 4912 D GLUCOSE METABOLISM//CHILDRENS DIABET//PANCREATIC ISLETS
4 22680 GK RAT//INSULIN GLUCOSE CLAMP//PHOSPHORYLATIVE SYSTEM
5 7605 PANDER//FAM3B//BIOCHEM IMMUNE SYST
6 22797 ACIPIMOX//BETA PYRIDYLCARBINOL//4 BROMOCROTONIC ACID
7 28679 GERIATR MED NEPHROL B6//AUTOPHAGY//ADENOVIRAL BCL XL
8 11202 INSULIN SECRETION//TIME DEPENDENT SUPPRESSION//MOL MED L6 01BENDOCRINE DIABET UNIT
9 4447 INTRAMYOCELLULAR LIPIDS//IMCL//INTRAMUSCULAR TRIGLYCERIDES
10 33859 GLUCOSE AND GLUTAMINE//ABT INVAS METASTASIERUNG//ACYL COA DEACYLASES

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