Class information for:
Level 1: K 2P CHANNELS//TREK 1//TWO PORE DOMAIN POTASSIUM CHANNEL

Basic class information
Class id #P Avg. number of
references		 Database coverage
of references
14468 768 47.5 92%


Bar chart of Publication_year

Last years might be incomplete

Hierarchy of classes
The table includes all classes above and classes immediately below the current class.


Cluster id Level Cluster label #P
8 4 CARDIAC & CARDIOVASCULAR SYSTEM//PERIPHERAL VASCULAR DISEASES//CARDIOL 1276458
11 3       ATRIAL FIBRILLATION//CARDIAC & CARDIOVASCULAR SYSTEM//CATHETER ABLATION 130936
691 2             POTASSIUM CHANNELS//BK CHANNEL//RETIGABINE 13105
14468 1                   K 2P CHANNELS//TREK 1//TWO PORE DOMAIN POTASSIUM CHANNEL 768

Terms with highest relevance score


rank Term termType Chi square Shr. of publ. in
class containing
term		 Class's shr. of
term's tot. occurrences		 #P with
term in
class
1 K 2P CHANNELS authKW 2458281 9% 90% 69
2 TREK 1 authKW 1832121 8% 79% 58
3 TWO PORE DOMAIN POTASSIUM CHANNEL authKW 944550 4% 85% 28
4 KCNK authKW 536727 2% 75% 18
5 TRESK authKW 526208 2% 88% 15
6 2P DOMAIN K CHANNELS authKW 516856 2% 100% 13
7 TWO PORE DOMAIN K CHANNEL authKW 440397 2% 92% 12
8 TREK 2 authKW 419941 2% 81% 13
9 TASK 1 authKW 391453 2% 62% 16
10 TASK 3 authKW 357818 2% 75% 12

Web of Science journal categories


Rank Term Chi square Shr. of publ. in
class containing
term		 Class's shr. of
term's tot. occurrences		 #P with
term in
class
1 Physiology 3230 23% 0% 175
2 Neurosciences 2154 32% 0% 245
3 Biochemistry & Molecular Biology 625 27% 0% 205
4 Cell Biology 543 15% 0% 117
5 Pharmacology & Pharmacy 313 14% 0% 108
6 Biophysics 174 7% 0% 50
7 Anesthesiology 98 2% 0% 19
8 Cardiac & Cardiovascular System 43 4% 0% 33
9 Medicine, Research & Experimental 32 4% 0% 28
10 Peripheral Vascular Diseases 25 2% 0% 19

Address terms


Rank Term Chi square Shr. of publ. in
class containing
term		 Class's shr. of
term's tot. occurrences		 #P with
term in
class
1 PHARMACOL MOL CELLULAIRE 297891 11% 9% 88
2 PAUL HAMEL 130112 1% 55% 6
3 PHYSIOL NEUROPATHOPHYSIOL 1 114589 1% 41% 7
4 MED NEURAL DYSFUNCT 110129 2% 21% 13
5 UMR 6097 96285 3% 9% 26
6 GENET HERZERKRANKUNGEN IFGH 89454 0% 75% 3
7 EX ICST 84806 1% 27% 8
8 ADCP 79516 0% 100% 2
9 PEDIATSECT DEV BIOL BIOPHYS 79516 0% 100% 2
10 UNIV CLIN ANESTHESIA INTENS CARE MED 79516 0% 100% 2

Journals


Rank Term Chi square Shr. of publ. in
class containing
term		 Class's shr. of
term's tot. occurrences		 #P with
term in
class
1 PFLUGERS ARCHIV-EUROPEAN JOURNAL OF PHYSIOLOGY 9311 6% 1% 44
2 CHANNELS 3711 1% 1% 7
3 JOURNAL OF PHYSIOLOGY-LONDON 3429 5% 0% 40
4 KOREAN JOURNAL OF PHYSIOLOGY & PHARMACOLOGY 1007 1% 1% 4
5 EMBO JOURNAL 899 3% 0% 20
6 MOLECULAR AND CELLULAR NEUROSCIENCE 899 1% 0% 8
7 MOLECULAR PHARMACOLOGY 893 2% 0% 15
8 AMERICAN JOURNAL OF PHYSIOLOGY-CELL PHYSIOLOGY 778 2% 0% 12
9 JOURNAL OF BIOLOGICAL CHEMISTRY 719 7% 0% 55
10 CURRENT TOPICS IN MEMBRANES 669 0% 1% 3

Author Key Words


Rank Term Chi square Shr. of publ. in
class containing
term		 Class's shr. of
term's tot. occurrences		 #P with
term in
class		 LCSH search Wikipedia search
1 K 2P CHANNELS 2458281 9% 90% 69 Search K+2P+CHANNELS Search K+2P+CHANNELS
2 TREK 1 1832121 8% 79% 58 Search TREK+1 Search TREK+1
3 TWO PORE DOMAIN POTASSIUM CHANNEL 944550 4% 85% 28 Search TWO+PORE+DOMAIN+POTASSIUM+CHANNEL Search TWO+PORE+DOMAIN+POTASSIUM+CHANNEL
4 KCNK 536727 2% 75% 18 Search KCNK Search KCNK
5 TRESK 526208 2% 88% 15 Search TRESK Search TRESK
6 2P DOMAIN K CHANNELS 516856 2% 100% 13 Search 2P+DOMAIN+K+CHANNELS Search 2P+DOMAIN+K+CHANNELS
7 TWO PORE DOMAIN K CHANNEL 440397 2% 92% 12 Search TWO+PORE+DOMAIN+K+CHANNEL Search TWO+PORE+DOMAIN+K+CHANNEL
8 TREK 2 419941 2% 81% 13 Search TREK+2 Search TREK+2
9 TASK 1 391453 2% 62% 16 Search TASK+1 Search TASK+1
10 TASK 3 357818 2% 75% 12 Search TASK+3 Search TASK+3

Core articles
The table includes core articles in the class. The following variables is taken into account for the relevance score of an article in a cluster c:
(1) Number of references referring to publications in the class.
(2) Share of total number of active references referring to publications in the class.
(3) Age of the article. New articles get higher score than old articles.
(4) Citation rate, normalized to year.


Rank Reference # ref. in
cl.		 Shr. of ref. in
cl.		 Citations
1 ENYEDI, P , CZIRJAK, G , (2010) MOLECULAR BACKGROUND OF LEAK K+ CURRENTS: TWO-PORE DOMAIN POTASSIUM CHANNELS.PHYSIOLOGICAL REVIEWS. VOL. 90. ISSUE 2. P. 559 -605 211 62% 275
2 FELICIANGELI, S , CHATELAIN, FC , BICHET, D , LESAGE, F , (2015) THE FAMILY OF K-2P CHANNELS: SALIENT STRUCTURAL AND FUNCTIONAL PROPERTIES.JOURNAL OF PHYSIOLOGY-LONDON. VOL. 593. ISSUE 12. P. 2587 -2603 159 85% 11
3 RENIGUNTA, V , SCHLICHTHORL, G , DAUT, J , (2015) MUCH MORE THAN A LEAK: STRUCTURE AND FUNCTION OF K-2P-CHANNELS.PFLUGERS ARCHIV-EUROPEAN JOURNAL OF PHYSIOLOGY. VOL. 467. ISSUE 5. P. 867 -894 176 71% 8
4 LOTSHAW, DP , (2007) BIOPHYSICAL, PHARMACOLOGICAL, FUNCTIONAL CHARACTERISTICS OF CLONED AND NATIVE MAMMALIAN TWO-PORE DOMAIN K+ CHANNELS.CELL BIOCHEMISTRY AND BIOPHYSICS. VOL. 47. ISSUE 2. P. 209-256 167 83% 85
5 MATHIE, A , VEALE, EL , (2015) TWO-PORE DOMAIN POTASSIUM CHANNELS: POTENTIAL THERAPEUTIC TARGETS FOR THE TREATMENT OF PAIN.PFLUGERS ARCHIV-EUROPEAN JOURNAL OF PHYSIOLOGY. VOL. 467. ISSUE 5. P. 931 -943 88 85% 10
6 NOEL, J , SANDOZ, G , LESAGE, F , (2011) MOLECULAR REGULATIONS GOVERNING TREK AND TRAAK CHANNEL FUNCTIONS.CHANNELS. VOL. 5. ISSUE 5. P. 400 -407 77 88% 39
7 KIM, D , (2005) PHYSIOLOGY AND PHARMACOLOGY OF TWO-PORE DOMAIN POTASSIUM CHANNELS.CURRENT PHARMACEUTICAL DESIGN. VOL. 11. ISSUE 21. P. 2717-2736 106 72% 87
8 LESAGE, F , BARHANIN, J , (2011) MOLECULAR PHYSIOLOGY OF PH-SENSITIVE BACKGROUND K-2P CHANNELS.PHYSIOLOGY. VOL. 26. ISSUE 6. P. 424-437 85 79% 26
9 VIVIER, D , BENNIS, K , LESAGE, F , DUCKI, S , (2016) PERSPECTIVES ON THE TWO-PORE DOMAIN POTASSIUM CHANNEL TREK-1 (TWIK-RELATED K+ CHANNEL 1). A NOVEL THERAPEUTIC TARGET?.JOURNAL OF MEDICINAL CHEMISTRY. VOL. 59. ISSUE 11. P. 5149 -5157 51 96% 3
10 DEDMAN, A , SHARIF-NAEINI, R , FOLGERING, JHA , DUPRAT, F , PATEL, A , HONORE, E , (2009) THE MECHANO-GATED K-2P CHANNEL TREK-1.EUROPEAN BIOPHYSICS JOURNAL WITH BIOPHYSICS LETTERS. VOL. 38. ISSUE 3. P. 293 -303 63 86% 49

Classes with closest relation at Level 1


Rank Class id link
1 14321 MECHANOSENSITIVE CHANNEL//MSCL//PIEZO2
2 37510 BVES//STAHLMAN CARDIOVASC S//POPDC
3 13321 NEUROSCI SOLUT CANC GRP//EAG1//ETHER A GO GO
4 27426 RILUZOLE//PK 26124//1 METHYL 4 PHENYLPYRIDIUM
5 5440 GIRK//ANDERSEN TAWIL SYNDROME//INWARD RECTIFIER
6 2165 CAROTID BODY//GLOMUS CELLS//SYST BIOL SENSING O2
7 11907 GLOMERULOSA CELLS//ALDOSTERONE SECRETION//ADRENAL GLOMERULOSA
8 2318 KCSA//JOURNAL OF GENERAL PHYSIOLOGY//MOL NEUROBIOL BIOPHYS
9 7179 DENDROTOXIN//EPISODIC ATAXIA TYPE 1//KCNA1
10 3493 ANESTHETIC MECHANISMS//HALOTHANE//GENERAL ANESTHETICS

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