Class information for:
Level 1: CANAVAN DISEASE//N ACETYLASPARTYLGLUTAMATE//ASPARTOACYLASE

Basic class information
Class id #P Avg. number of
references		 Database coverage
of references
15744 695 38.2 76%


Bar chart of Publication_year

Last years might be incomplete

Hierarchy of classes
The table includes all classes above and classes immediately below the current class.


Cluster id Level Cluster label #P
0 4 BIOCHEMISTRY & MOLECULAR BIOLOGY//CELL BIOLOGY//ONCOLOGY 4064930
385 3       MICROGLIA//MAGNETIC RESONANCE SPECTROSCOPY//LITHIUM 31368
2761 2             CANAVAN DISEASE//N ACETYLASPARTYLGLUTAMATE//N ACETYLASPARTATE 3180
15744 1                   CANAVAN DISEASE//N ACETYLASPARTYLGLUTAMATE//ASPARTOACYLASE 695

Terms with highest relevance score


rank Term termType Chi square Shr. of publ. in
class containing
term		 Class's shr. of
term's tot. occurrences		 #P with
term in
class
1 CANAVAN DISEASE authKW 3882168 16% 82% 108
2 N ACETYLASPARTYLGLUTAMATE authKW 2506060 11% 77% 74
3 ASPARTOACYLASE authKW 2130475 8% 85% 57
4 NAAG authKW 1533898 6% 78% 45
5 N ACETYLASPARTIC ACID authKW 689573 3% 83% 19
6 N ACETYLASPARTATE authKW 569539 13% 14% 93
7 N ACETYLASPARTYLGLUTAMATE NAAG authKW 421766 2% 80% 12
8 GLUTAMATE CARBOXYPEPTIDASE II authKW 380977 3% 38% 23
9 MOLECULAR WATER PUMPS authKW 355867 1% 90% 9
10 N ACETYL L ASPARTATE authKW 331185 2% 54% 14

Web of Science journal categories


Rank Term Chi square Shr. of publ. in
class containing
term		 Class's shr. of
term's tot. occurrences		 #P with
term in
class
1 Neurosciences 5263 51% 0% 351
2 Biochemistry & Molecular Biology 649 28% 0% 196
3 Clinical Neurology 578 14% 0% 96
4 Medicine, Research & Experimental 451 11% 0% 73
5 Genetics & Heredity 232 9% 0% 62
6 Pediatrics 142 6% 0% 41
7 Pharmacology & Pharmacy 116 10% 0% 70
8 Endocrinology & Metabolism 102 6% 0% 41
9 Biochemical Research Methods 22 3% 0% 20
10 Psychiatry 16 3% 0% 20

Address terms


Rank Term Chi square Shr. of publ. in
class containing
term		 Class's shr. of
term's tot. occurrences		 #P with
term in
class
1 PHARMACEUT THER Y NEUROPHARMACOL 100410 1% 29% 8
2 ANAT PHYSIOL GENET 99473 5% 7% 32
3 NSF BIOPHON SCI TECHNOL 87869 0% 100% 2
4 PEDIAT HUMAN BIOL CHEM GENET 58578 0% 67% 2
5 HUMAN DEV CONSUMER SCI 56484 0% 43% 3
6 NEUROTRANSLAT DRUG DISCOVERY PROGRAM 54068 1% 31% 4
7 BIOSCI FRE 3005CNRS BIOCHIM BIOL NUTRSERV 43934 0% 100% 1
8 BRAZILIAN NEUROSCI NEUROTECHNOL 43934 0% 100% 1
9 CHAIR NERVOUSE DIS REGENERAT MED 43934 0% 100% 1
10 CIENCIAS SECC GENET EVOLUT 43934 0% 100% 1

Journals


Rank Term Chi square Shr. of publ. in
class containing
term		 Class's shr. of
term's tot. occurrences		 #P with
term in
class
1 JOURNAL OF NEUROCHEMISTRY 9158 9% 0% 66
2 JOURNAL OF INHERITED METABOLIC DISEASE 6531 4% 1% 26
3 NEUROPEDIATRICS 1739 1% 0% 9
4 BRAIN RESEARCH 1435 6% 0% 40
5 METABOLIC BRAIN DISEASE 1104 1% 0% 6
6 JOURNAL OF MOLECULAR NEUROSCIENCE 1022 1% 0% 8
7 NEUROCHEMICAL RESEARCH 999 2% 0% 13
8 ADVANCES IN EXPERIMENTAL MEDICINE AND BIOLOGY 929 3% 0% 19
9 NEUROCHEMISTRY INTERNATIONAL 653 1% 0% 9
10 NMR IN BIOMEDICINE 480 1% 0% 5

Author Key Words


Rank Term Chi square Shr. of publ. in
class containing
term		 Class's shr. of
term's tot. occurrences		 #P with
term in
class		 LCSH search Wikipedia search
1 CANAVAN DISEASE 3882168 16% 82% 108 Search CANAVAN+DISEASE Search CANAVAN+DISEASE
2 N ACETYLASPARTYLGLUTAMATE 2506060 11% 77% 74 Search N+ACETYLASPARTYLGLUTAMATE Search N+ACETYLASPARTYLGLUTAMATE
3 ASPARTOACYLASE 2130475 8% 85% 57 Search ASPARTOACYLASE Search ASPARTOACYLASE
4 NAAG 1533898 6% 78% 45 Search NAAG Search NAAG
5 N ACETYLASPARTIC ACID 689573 3% 83% 19 Search N+ACETYLASPARTIC+ACID Search N+ACETYLASPARTIC+ACID
6 N ACETYLASPARTATE 569539 13% 14% 93 Search N+ACETYLASPARTATE Search N+ACETYLASPARTATE
7 N ACETYLASPARTYLGLUTAMATE NAAG 421766 2% 80% 12 Search N+ACETYLASPARTYLGLUTAMATE+NAAG Search N+ACETYLASPARTYLGLUTAMATE+NAAG
8 GLUTAMATE CARBOXYPEPTIDASE II 380977 3% 38% 23 Search GLUTAMATE+CARBOXYPEPTIDASE+II Search GLUTAMATE+CARBOXYPEPTIDASE+II
9 MOLECULAR WATER PUMPS 355867 1% 90% 9 Search MOLECULAR+WATER+PUMPS Search MOLECULAR+WATER+PUMPS
10 N ACETYL L ASPARTATE 331185 2% 54% 14 Search N+ACETYL+L+ASPARTATE Search N+ACETYL+L+ASPARTATE

Core articles
The table includes core articles in the class. The following variables is taken into account for the relevance score of an article in a cluster c:
(1) Number of references referring to publications in the class.
(2) Share of total number of active references referring to publications in the class.
(3) Age of the article. New articles get higher score than old articles.
(4) Citation rate, normalized to year.


Rank Reference # ref. in
cl.		 Shr. of ref. in
cl.		 Citations
1 ROSCOE, RB , ELLIOTT, C , ZARROS, A , BAILLIE, GS , (2016) NON-GENETIC THERAPEUTIC APPROACHES TO CANAVAN DISEASE.JOURNAL OF THE NEUROLOGICAL SCIENCES. VOL. 366. ISSUE . P. 116 -124 63 88% 2
2 JURDAKOVA, H , GOROVA, R , ADDOVA, G , BEHULOVA, D , OSTROVSKY, I , (2017) THE STATE OF TREATMENT APPROACH AND DIAGNOSTICS IN CANAVAN DISEASE WITH FOCUS ON THE DETERMINATION OF N-ACETYLASPARIC ACID.CHEMICAL PAPERS. VOL. 71. ISSUE 1. P. 29 -40 77 79% 0
3 NEALE, JH , OLSZEWSKI, RT , ZUO, DY , JANCZURA, KJ , PROFACI, CP , LAVIN, KM , MADORE, JC , BZDEGA, T , (2011) ADVANCES IN UNDERSTANDING THE PEPTIDE NEUROTRANSMITTER NAAG AND APPEARANCE OF A NEW MEMBER OF THE NAAG NEUROPEPTIDE FAMILY.JOURNAL OF NEUROCHEMISTRY. VOL. 118. ISSUE 4. P. 490 -498 71 79% 29
4 MOFFETT, JR , ROSS, B , ARUN, P , MADHAVARAO, CN , NAMBOODIRI, AMA , (2007) N-ACETYLASPARTATE IN THE CNS: FROM NEURODIAGNOSTICS TO NEUROBIOLOGY.PROGRESS IN NEUROBIOLOGY. VOL. 81. ISSUE 2. P. 89 -131 109 33% 475
5 LEONE, P , SHERA, D , MCPHEE, SWJ , FRANCIS, JS , KOLODNY, EH , BILANIUK, LT , WANG, DJ , ASSADI, M , GOLDFARB, O , GOLDMAN, HW , ET AL (2012) LONG-TERM FOLLOW-UP AFTER GENE THERAPY FOR CANAVAN DISEASE.SCIENCE TRANSLATIONAL MEDICINE. VOL. 4. ISSUE 165. P. - 49 83% 43
6 NEALE, JH , BZDEGA, T , WROBLEWSKA, B , (2000) N-ACETYLASPARTYLGLUTAMATE: THE MOST ABUNDANT PEPTIDE NEUROTRANSMITTER IN THE MAMMALIAN CENTRAL NERVOUS SYSTEM.JOURNAL OF NEUROCHEMISTRY. VOL. 75. ISSUE 2. P. 443-452 70 73% 189
7 HOSHINO, H , KUBOTA, M , (2014) CANAVAN DISEASE: CLINICAL FEATURES AND RECENT ADVANCES IN RESEARCH.PEDIATRICS INTERNATIONAL. VOL. 56. ISSUE 4. P. 477 -483 39 91% 13
8 ZAYED, H , (2015) CANAVAN DISEASE: AN ARAB SCENARIO.GENE. VOL. 560. ISSUE 1. P. 9 -14 38 86% 3
9 BASLOW, MH , GUILFOYLE, DN , (2013) CANAVAN DISEASE, A RARE EARLY-ONSET HUMAN SPONGIFORM LEUKODYSTROPHY: INSIGHTS INTO ITS GENESIS AND POSSIBLE CLINICAL INTERVENTIONS.BIOCHIMIE. VOL. 95. ISSUE 4. P. 946-956 41 71% 14
10 LODDER-GADACZEK, J , BECKER, I , GIESELMANN, V , WANG-ECKHARDT, L , ECKHARDT, M , (2011) N-ACETYLASPARTYLGLUTAMATE SYNTHETASE II SYNTHESIZES N-ACETYLASPARTYLGLUTAMYLGLUTAMATE.JOURNAL OF BIOLOGICAL CHEMISTRY. VOL. 286. ISSUE 19. P. 16693-16706 34 89% 9

Classes with closest relation at Level 1


Rank Class id link
1 31341 ATTRACTIN//ZITTER RAT//SPONTANEOUSLY EPILEPTIC RAT SER
2 6169 PSMA//PROSTATE SPECIFIC MEMBRANE ANTIGEN//C 11 CHOLINE
3 13294 N ACETYLASPARTATE//MOL DYNAM MENTAL DISORDERS//MAGNETIC RESONANCE SPECTROSCOPY
4 1379 MAGNETIC RESONANCE IN MEDICINE//MAGNETIC RESONANCE SPECTROSCOPY//SPECTROSCOPIC IMAGING
5 12781 ALEXANDER DISEASE//LEUKODYSTROPHY//ROSENTHAL FIBERS
6 22614 AMINOACYLASE//L AMINOACYLASE//D AMINOACYLASE
7 5639 HOMOCYSTEATE//2 AMINO 4 PHOSPHONOBUTANOIC ACID//BETA P CHLOROPHENYLGLUTAMATE
8 287 METABOTROPIC GLUTAMATE RECEPTOR//MGLUR5//MPEP
9 25197 GPR91//SUCCINATE//SLC13A5
10 18428 PARALYSIS//MEMBRANE SEALING//CRAYFISH MEDIAL GIANT AXON

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