Class information for: |
Basic class information |
| Class id | #P | Avg. number of references |
Database coverage of references |
|---|---|---|---|
| 16240 | 665 | 38.7 | 64% |
Hierarchy of classes |
The table includes all classes above and classes immediately below the current class. |
| Cluster id | Level | Cluster label | #P |
|---|---|---|---|
| 0 | 4 | BIOCHEMISTRY & MOLECULAR BIOLOGY//CELL BIOLOGY//ONCOLOGY | 4064930 |
| 468 | 3 | GLUCOSINOLATES//BILIRUBIN//HEME OXYGENASE | 24157 |
| 1296 | 2 | HEME OXYGENASE//PORPHYRIA//HEME OXYGENASE 1 | 8624 |
| 16240 | 1 | X LINKED SIDEROBLASTIC ANEMIA//ALAS2//5 AMINOLEVULINATE SYNTHASE | 665 |
Terms with highest relevance score |
| rank | Term | termType | Chi square | Shr. of publ. in class containing term |
Class's shr. of term's tot. occurrences |
#P with term in class |
|---|---|---|---|---|---|---|
| 1 | X LINKED SIDEROBLASTIC ANEMIA | authKW | 642831 | 2% | 100% | 14 |
| 2 | ALAS2 | authKW | 559737 | 2% | 76% | 16 |
| 3 | 5 AMINOLEVULINATE SYNTHASE | authKW | 524743 | 3% | 57% | 20 |
| 4 | SIDEROBLASTIC ANEMIA | authKW | 462838 | 4% | 40% | 25 |
| 5 | CONGENITAL SIDEROBLASTIC ANEMIA | authKW | 321416 | 1% | 100% | 7 |
| 6 | PORFIRINAS | address | 249987 | 1% | 78% | 7 |
| 7 | FLVCR1 | authKW | 206621 | 1% | 75% | 6 |
| 8 | AMINOLEVULINATE SYNTHASE | authKW | 204532 | 1% | 64% | 7 |
| 9 | DELTA AMINOLEVULINATE SYNTHASE | authKW | 148758 | 1% | 36% | 9 |
| 10 | DIABETIC RAT HEPATOCYTES | authKW | 137750 | 0% | 100% | 3 |
Web of Science journal categories |
| Rank | Term | Chi square | Shr. of publ. in class containing term |
Class's shr. of term's tot. occurrences |
#P with term in class |
|---|---|---|---|---|---|
| 1 | Hematology | 3864 | 24% | 0% | 157 |
| 2 | Biochemistry & Molecular Biology | 1935 | 46% | 0% | 303 |
| 3 | Biophysics | 685 | 12% | 0% | 83 |
| 4 | Medicine, Research & Experimental | 247 | 8% | 0% | 55 |
| 5 | Cell Biology | 197 | 11% | 0% | 71 |
| 6 | Genetics & Heredity | 161 | 8% | 0% | 52 |
| 7 | Pediatrics | 10 | 2% | 0% | 16 |
| 8 | Geriatrics & Gerontology | 9 | 1% | 0% | 6 |
| 9 | Medicine, General & Internal | 8 | 3% | 0% | 23 |
| 10 | Medical Laboratory Technology | 6 | 1% | 0% | 5 |
Address terms |
| Rank | Term | Chi square | Shr. of publ. in class containing term |
Class's shr. of term's tot. occurrences |
#P with term in class |
|---|---|---|---|---|---|
| 1 | PORFIRINAS | 249987 | 1% | 78% | 7 |
| 2 | BIOCHEM HEMATOL | 47859 | 1% | 15% | 7 |
| 3 | ANIM SCI 2413 | 45917 | 0% | 100% | 1 |
| 4 | BIOCHEM PEPTIDSYNTH | 45917 | 0% | 100% | 1 |
| 5 | BIOINFORMAT SHARED OURCES | 45917 | 0% | 100% | 1 |
| 6 | BIOL MOL REGULAC EXP GEN | 45917 | 0% | 100% | 1 |
| 7 | CHILDRENS HOSP BOSTONHEMAT ONCOL | 45917 | 0% | 100% | 1 |
| 8 | CLIN ANESTHESIOL SURG ANAT PATHOL DERMATOL H | 45917 | 0% | 100% | 1 |
| 9 | DIATOM FUNCT GENOMUMR 7238 | 45917 | 0% | 100% | 1 |
| 10 | INSERMU773 GENET MOL | 45917 | 0% | 100% | 1 |
Journals |
| Rank | Term | Chi square | Shr. of publ. in class containing term |
Class's shr. of term's tot. occurrences |
#P with term in class |
|---|---|---|---|---|---|
| 1 | BAILLIERES CLINICAL HAEMATOLOGY-INTERNATIONAL PRACTICE AND RESEARCH | 4172 | 0% | 9% | 1 |
| 2 | EXPERIMENTAL HEMATOLOGY | 2583 | 3% | 0% | 18 |
| 3 | INTERNATIONAL JOURNAL OF CELL CLONING | 1693 | 1% | 1% | 4 |
| 4 | ENZYME | 1513 | 1% | 1% | 5 |
| 5 | AMERICAN JOURNAL OF HEMATOLOGY | 1494 | 2% | 0% | 14 |
| 6 | SCANDINAVIAN JOURNAL OF HAEMATOLOGY | 1471 | 1% | 1% | 6 |
| 7 | BLOOD CELLS MOLECULES AND DISEASES | 1256 | 1% | 0% | 7 |
| 8 | ARCHIVES OF BIOCHEMISTRY AND BIOPHYSICS | 1161 | 3% | 0% | 21 |
| 9 | BRITISH JOURNAL OF HAEMATOLOGY | 1077 | 3% | 0% | 18 |
| 10 | INTERNATIONAL JOURNAL OF BIOCHEMISTRY | 957 | 1% | 0% | 8 |
Author Key Words |
Core articles |
The table includes core articles in the class. The following variables is taken into account for the relevance score of an article in a cluster c: (1) Number of references referring to publications in the class. (2) Share of total number of active references referring to publications in the class. (3) Age of the article. New articles get higher score than old articles. (4) Citation rate, normalized to year. |
| Rank | Reference | # ref. in cl. |
Shr. of ref. in cl. |
Citations |
|---|---|---|---|---|
| 1 | FRATZ, EJ , CLAYTON, J , HUNTER, GA , DUCAMP, S , BREYDO, L , UVERSKY, VN , DEYBACH, JC , GOUYA, L , PUY, H , FERREIRA, GC , (2015) HUMAN ERYTHROID 5-AMINOLEVULINATE SYNTHASE MUTATIONS ASSOCIATED WITH X-LINKED PROTOPORPHYRIA DISRUPT THE CONFORMATIONAL EQUILIBRIUM AND ENHANCE PRODUCT RELEASE.BIOCHEMISTRY. VOL. 54. ISSUE 36. P. 5617 -5631 | 40 | 75% | 1 |
| 2 | KADIRVEL, S , FURUYAMA, K , HARIGAE, H , KANEKO, K , TAMAI, Y , ISHIDA, Y , SHIBAHARA, S , (2012) THE CARBOXYL-TERMINAL REGION OF ERYTHROID-SPECIFIC 5-AMINOLEVULINATE SYNTHASE ACTS AS AN INTRINSIC MODIFIER FOR ITS CATALYTIC ACTIVITY AND PROTEIN STABILITY.EXPERIMENTAL HEMATOLOGY. VOL. 40. ISSUE 6. P. 477-486 | 36 | 86% | 6 |
| 3 | DUCAMP, S , KANNENGIESSER, C , TOUATI, M , GARCON, L , GUERCI-BRESLER, A , GUICHARD, JF , VERMYLEN, C , DOCHIR, J , POIREL, HA , FOUYSSAC, F , ET AL (2011) SIDEROBLASTIC ANEMIA: MOLECULAR ANALYSIS OF THE ALAS2 GENE IN A SERIES OF 29 PROBANDS AND FUNCTIONAL STUDIES OF 10 MISSENSE MUTATIONS.HUMAN MUTATION. VOL. 32. ISSUE 6. P. 590 -597 | 30 | 75% | 21 |
| 4 | FURUYAMA, K , HARIGAE, H , HELLER, T , HAMEL, BCJ , MINDER, EI , SHIMIZU, T , KURIBARA, T , BLIJLEVENS, N , SHIBAHARA, S , SASSA, S , (2006) ARG452 SUBSTITUTION OF THE ERYTHROID-SPECIFIC 5-AMINOLAEVULINATE SYNTHASE, A HOT SPOT MUTATION IN X-LINKED SIDEROBLASTIC ANAEMIA, DOES NOT ITSELF AFFECT ENZYME ACTIVITY.EUROPEAN JOURNAL OF HAEMATOLOGY. VOL. 76. ISSUE 1. P. 33 -41 | 27 | 93% | 11 |
| 5 | STOJANOVSKI, BM , FERREIRA, GC , (2015) MURINE ERYTHROID 5-AMINOLEVULINATE SYNTHASE: ADENOSYL-BINDING SITE LYS221 MODULATES SUBSTRATE BINDING AND CATALYSIS.FEBS OPEN BIO. VOL. 5. ISSUE . P. 824 -831 | 21 | 88% | 0 |
| 6 | BISHOP, DF , TCHAIKOVSKII, V , HOFFBRAND, AV , FRASER, ME , MARGOLIS, S , (2012) X-LINKED SIDEROBLASTIC ANEMIA DUE TO CARBOXYL-TERMINAL ALAS2 MUTATIONS THAT CAUSE LOSS OF BINDING TO THE BETA-SUBUNIT OF SUCCINYL-COA SYNTHETASE (SUCLA2).JOURNAL OF BIOLOGICAL CHEMISTRY. VOL. 287. ISSUE 34. P. 28943-28955 | 24 | 75% | 13 |
| 7 | FLEMING, MD , (2002) THE GENETICS OF INHERITED SIDEROBLASTIC ANEMIAS.SEMINARS IN HEMATOLOGY. VOL. 39. ISSUE 4. P. 270-281 | 44 | 51% | 46 |
| 8 | FERREIRA, GC , GONG, J , (1995) 5-AMINOLEVULINATE SYNTHASE AND THE FIRST STEP OF HEME-BIOSYNTHESIS.JOURNAL OF BIOENERGETICS AND BIOMEMBRANES. VOL. 27. ISSUE 2. P. 151-159 | 42 | 66% | 51 |
| 9 | COX, TC , SADLON, TJ , SCHWARZ, QP , MATTHEWS, CS , WISE, PD , COX, LL , BOTTOMLEY, SS , MAY, BK , (2004) THE MAJOR SPLICE VARIANT OF HUMAN 5-AMINOLEVULINATE SYNTHASE-2 CONTRIBUTES SIGNIFICANTLY TO ERYTHROID HEME BIOSYNTHESIS.INTERNATIONAL JOURNAL OF BIOCHEMISTRY & CELL BIOLOGY. VOL. 36. ISSUE 2. P. 281-295 | 27 | 77% | 9 |
| 10 | MAY, A , BISHOP, DF , (1998) THE MOLECULAR BIOLOGY AND PYRIDOXINE RESPONSIVENESS OF X-LINKED SIDEROBLASTIC ANAEMIA.HAEMATOLOGICA. VOL. 83. ISSUE 1. P. 56-70 | 36 | 63% | 48 |
Classes with closest relation at Level 1 |