Class information for:
Level 1: TRPV1//CAPSAICIN//RESINIFERATOXIN

Basic class information
Class id #P Avg. number of
references		 Database coverage
of references
1728 2515 43.8 82%


Bar chart of Publication_year

Last years might be incomplete

Hierarchy of classes
The table includes all classes above and classes immediately below the current class.


Cluster id Level Cluster label #P
11 4 NEUROSCIENCES//CLINICAL NEUROLOGY//NEUROL 1112395
497 3       CANNABINOID//ANANDAMIDE//ENDOCANNABINOIDS 22707
1435 2             TRPV1//TRPA1//CAPSAICIN 7869
1728 1                   TRPV1//CAPSAICIN//RESINIFERATOXIN 2515

Terms with highest relevance score


rank Term termType Chi square Shr. of publ. in
class containing
term		 Class's shr. of
term's tot. occurrences		 #P with
term in
class
1 TRPV1 authKW 1856440 16% 39% 395
2 CAPSAICIN authKW 1342710 25% 18% 631
3 RESINIFERATOXIN authKW 909779 5% 56% 133
4 CAPSAZEPINE authKW 779341 4% 61% 106
5 VANILLOID RECEPTOR authKW 634234 5% 42% 125
6 TRPV1 ANTAGONIST authKW 547072 2% 87% 52
7 VANILLOID authKW 543313 3% 51% 88
8 VR1 authKW 449504 2% 63% 59
9 VANILLOID RECEPTOR 1 authKW 368911 2% 62% 49
10 CAPSAICIN RECEPTOR authKW 241924 1% 59% 34

Web of Science journal categories


Rank Term Chi square Shr. of publ. in
class containing
term		 Class's shr. of
term's tot. occurrences		 #P with
term in
class
1 Neurosciences 11212 39% 0% 992
2 Pharmacology & Pharmacy 4788 27% 0% 677
3 Anesthesiology 1936 6% 0% 140
4 Chemistry, Medicinal 1657 8% 0% 208
5 Physiology 1326 9% 0% 221
6 Clinical Neurology 227 6% 0% 144
7 Biochemistry & Molecular Biology 148 11% 0% 282
8 Chemistry, Organic 87 4% 0% 111
9 Behavioral Sciences 75 2% 0% 43
10 Medicine, Research & Experimental 71 3% 0% 81

Address terms


Rank Term Chi square Shr. of publ. in
class containing
term		 Class's shr. of
term's tot. occurrences		 #P with
term in
class
1 SENSORY GRP 64739 0% 67% 8
2 LEADING MOL MODELING DRUG DESIGN 61448 0% 56% 9
3 NANOMED MOL INTERVENT 54071 0% 64% 7
4 GRUNENTHAL INNOVAT 51743 0% 47% 9
5 NEURONAL GENE EXP S UNIT 49564 0% 58% 7
6 CORE CELL SIGNALING DRUG DISCOVERY 45693 0% 47% 8
7 CELLULAR CARCINOGENESIS TUMOR PROMOT 43793 1% 11% 34
8 ENDOCANNABINOID GRP 42087 2% 8% 41
9 PRECLIN COMPOUND PROFILING 36418 0% 100% 3
10 MOL MECHANISMS TUMOR PROMOT SECT 25285 0% 42% 5

Journals


Rank Term Chi square Shr. of publ. in
class containing
term		 Class's shr. of
term's tot. occurrences		 #P with
term in
class
1 MOLECULAR PAIN 11843 1% 3% 29
2 PAIN 9582 3% 1% 79
3 NEUROSCIENCE LETTERS 5947 5% 0% 125
4 NAUNYN-SCHMIEDEBERGS ARCHIVES OF PHARMACOLOGY 5341 2% 1% 52
5 ACTA PHYSIOLOGICA HUNGARICA 4757 1% 2% 22
6 EUROPEAN JOURNAL OF PHARMACOLOGY 4355 4% 0% 102
7 NEUROSCIENCE 3879 3% 0% 85
8 BRITISH JOURNAL OF PHARMACOLOGY 3442 3% 0% 72
9 BRAIN RESEARCH 2221 4% 0% 96
10 BIOORGANIC & MEDICINAL CHEMISTRY LETTERS 2121 3% 0% 68

Author Key Words


Rank Term Chi square Shr. of publ. in
class containing
term		 Class's shr. of
term's tot. occurrences		 #P with
term in
class		 LCSH search Wikipedia search
1 TRPV1 1856440 16% 39% 395 Search TRPV1 Search TRPV1
2 CAPSAICIN 1342710 25% 18% 631 Search CAPSAICIN Search CAPSAICIN
3 RESINIFERATOXIN 909779 5% 56% 133 Search RESINIFERATOXIN Search RESINIFERATOXIN
4 CAPSAZEPINE 779341 4% 61% 106 Search CAPSAZEPINE Search CAPSAZEPINE
5 VANILLOID RECEPTOR 634234 5% 42% 125 Search VANILLOID+RECEPTOR Search VANILLOID+RECEPTOR
6 TRPV1 ANTAGONIST 547072 2% 87% 52 Search TRPV1+ANTAGONIST Search TRPV1+ANTAGONIST
7 VANILLOID 543313 3% 51% 88 Search VANILLOID Search VANILLOID
8 VR1 449504 2% 63% 59 Search VR1 Search VR1
9 VANILLOID RECEPTOR 1 368911 2% 62% 49 Search VANILLOID+RECEPTOR+1 Search VANILLOID+RECEPTOR+1
10 CAPSAICIN RECEPTOR 241924 1% 59% 34 Search CAPSAICIN+RECEPTOR Search CAPSAICIN+RECEPTOR

Core articles
The table includes core articles in the class. The following variables is taken into account for the relevance score of an article in a cluster c:
(1) Number of references referring to publications in the class.
(2) Share of total number of active references referring to publications in the class.
(3) Age of the article. New articles get higher score than old articles.
(4) Citation rate, normalized to year.


Rank Reference # ref. in
cl.		 Shr. of ref. in
cl.		 Citations
1 HOLZER, P , (1991) CAPSAICIN - CELLULAR TARGETS, MECHANISMS OF ACTION, AND SELECTIVITY FOR THIN SENSORY NEURONS.PHARMACOLOGICAL REVIEWS. VOL. 43. ISSUE 2. P. 143-201 227 49% 1415
2 HOLZER, P , (2008) THE PHARMACOLOGICAL CHALLENGE TO TAME THE TRANSIENT RECEPTOR POTENTIAL VANILLOID-1 (TRPV1) NOCISENSOR.BRITISH JOURNAL OF PHARMACOLOGY. VOL. 155. ISSUE 8. P. 1145 -1162 163 75% 84
3 SZALLASI, A , BLUMBERG, PM , (1999) VANILLOID (CAPSAICIN) RECEPTORS AND MECHANISMS.PHARMACOLOGICAL REVIEWS. VOL. 51. ISSUE 2. P. 159 -211 188 43% 1216
4 PREMKUMAR, LS , SIKAND, P , (2008) TRPV1: A TARGET FOR NEXT GENERATION ANALGESICS.CURRENT NEUROPHARMACOLOGY. VOL. 6. ISSUE 2. P. 151-163 138 72% 34
5 CUI, M , GOSU, V , BASITH, S , HONG, S , CHOI, S , (2016) POLYMODAL TRANSIENT RECEPTOR POTENTIAL VANILLOID TYPE 1 NOCISENSOR: STRUCTURE, MODULATORS, AND THERAPEUTIC APPLICATIONS.ION CHANNELS AS THERAPEUTIC TARGETS, PT B. VOL. 104. ISSUE . P. 81 -125 120 64% 2
6 VALENZANO, KJ , SUN, Q , (2004) CURRENT PERSPECTIVES ON THE THERAPEUTIC UTILITY OF VR1 ANTAGONISTS.CURRENT MEDICINAL CHEMISTRY. VOL. 11. ISSUE 24. P. 3185-3202 128 78% 33
7 BISHNOI, M , PREMKUMAR, LS , (2011) POSSIBLE CONSEQUENCES OF BLOCKING TRANSIENT RECEPTOR POTENTIAL VANILLOID 1.CURRENT PHARMACEUTICAL BIOTECHNOLOGY. VOL. 12. ISSUE 1. P. 102-114 142 59% 3
8 PREMKUMAR, LS , BISHNOI, M , (2011) DISEASE-RELATED CHANGES IN TRPV1 EXPRESSION AND ITS IMPLICATIONS FOR DRUG DEVELOPMENT.CURRENT TOPICS IN MEDICINAL CHEMISTRY. VOL. 11. ISSUE 17. P. 2192 -2209 154 52% 12
9 PALAZZO, E , LUONGO, L , DE NOVELLIS, V , ROSSI, F , MARABESE, I , MAIONE, S , (2012) TRANSIENT RECEPTOR POTENTIAL VANILLOID TYPE 1 AND PAIN DEVELOPMENT.CURRENT OPINION IN PHARMACOLOGY. VOL. 12. ISSUE 1. P. 9 -17 93 74% 28
10 SZALLASI, A , CORTRIGHT, DN , BLUM, CA , EID, SR , (2007) THE VANILLOID RECEPTOR TRPV1: 10 YEARS FROM CHANNEL CLONING TO ANTAGONIST PROOF-OF-CONCEPT.NATURE REVIEWS DRUG DISCOVERY. VOL. 6. ISSUE 5. P. 357 -372 93 55% 404

Classes with closest relation at Level 1


Rank Class id link
1 3008 TRPA1//TRPM8//TRPV4
2 4718 CAPSAICINOIDS//CAPSAICIN//CAPSINOIDS
3 13758 SECONDARY HYPERALGESIA//THERMAL GRILL ILLUSION//HYPERALGESIA
4 14003 SYMPATHETICALLY MAINTAINED PAIN//NIH PAIN//POLYMODAL RECEPTOR
5 21256 TANEZUMAB//FULRANUMAB//NERVE GROWTH FACTOR
6 27199 CYCLO SOMATOSTATIN//DEXTRAN OEDEMA//SST2A RECEPTOR
7 12382 ACID SENSING ION CHANNEL//ASIC3//APETX2
8 3163 CALCITONIN GENE RELATED PEPTIDE//CALCITONIN GENE RELATED PEPTIDE CGRP//CGRP
9 11896 FLUORIDE RESISTANT ACID PHOSPHATASE//PROJECTION FIELD//AB_2314660
10 2715 DORSAL HORN//SPINAL CORD GRP//SUBSTANTIA GELATINOSA

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