Class information for:
Level 1: OLTIPRAZ//1 2 DITHIOLE 3 THIONES//DITHIOLETHIONES

Basic class information
Class id #P Avg. number of
references		 Database coverage
of references
19296 512 29.4 56%


Bar chart of Publication_year

Last years might be incomplete

Hierarchy of classes
The table includes all classes above and classes immediately below the current class.


Cluster id Level Cluster label #P
5 4 CHEMISTRY, ORGANIC//CHEMISTRY, INORGANIC & NUCLEAR//CHEMISTRY, MULTIDISCIPLINARY 1745167
558 3       EBSELEN//DIPHENYL DISELENIDE//CIENCIAS NAT EXATAS 17618
1723 2             SECT HETEROORGAN CPDS//THIOCARBONYL YLIDES//LAWESSONS REAGENT 6620
19296 1                   OLTIPRAZ//1 2 DITHIOLE 3 THIONES//DITHIOLETHIONES 512

Terms with highest relevance score


rank Term termType Chi square Shr. of publ. in
class containing
term		 Class's shr. of
term's tot. occurrences		 #P with
term in
class
1 OLTIPRAZ authKW 1149891 7% 52% 37
2 1 2 DITHIOLE 3 THIONES authKW 717633 4% 63% 19
3 DITHIOLETHIONES authKW 603822 4% 56% 18
4 METAL CYCLOPENTADIENIDES authKW 178915 1% 100% 3
5 UP EA 2231 address 159033 1% 67% 4
6 CANCER PREVENTION EFFICACY authKW 134185 1% 75% 3
7 INVOLUCRIN EXPRESSION authKW 134185 1% 75% 3
8 1 2 DITHIOLE 3 ONES authKW 119277 0% 100% 2
9 3 7 DITHIATRICYCLO44002 8DECA 4 9 DIENE authKW 119277 0% 100% 2
10 3 IMINO 1 2 DITHIOLE authKW 119277 0% 100% 2

Web of Science journal categories


Rank Term Chi square Shr. of publ. in
class containing
term		 Class's shr. of
term's tot. occurrences		 #P with
term in
class
1 Chemistry, Organic 1139 22% 0% 114
2 Pharmacology & Pharmacy 658 23% 0% 116
3 Chemistry, Medicinal 386 9% 0% 45
4 Tropical Medicine 350 4% 0% 21
5 Toxicology 307 8% 0% 41
6 Oncology 224 13% 0% 65
7 Chemistry, Multidisciplinary 202 15% 0% 79
8 Chemistry, Inorganic & Nuclear 66 5% 0% 26
9 Crystallography 43 3% 0% 16
10 Public, Environmental & Occupational Health 41 5% 0% 26

Address terms


Rank Term Chi square Shr. of publ. in
class containing
term		 Class's shr. of
term's tot. occurrences		 #P with
term in
class
1 UP EA 2231 159033 1% 67% 4
2 CJ PHARMACEUT 119277 0% 100% 2
3 UP 2231 119277 0% 100% 2
4 INTERDISCIPLINARY PROGRAM CLIN PHARMACOL 76674 1% 43% 3
5 BIOCHIM NUTR EAD 948 59638 0% 100% 1
6 CHEMOPREVENT INVEST BRANCH 59638 0% 100% 1
7 CIENCIAS QIM 59638 0% 100% 1
8 DRUG METAB INFLAMMATORY DIS 59638 0% 100% 1
9 DRUG TARGETING CHINA EDUC MINIST 59638 0% 100% 1
10 ELECT ORGANOMET 59638 0% 100% 1

Journals


Rank Term Chi square Shr. of publ. in
class containing
term		 Class's shr. of
term's tot. occurrences		 #P with
term in
class
1 CARCINOGENESIS 3721 5% 0% 27
2 TROPENMEDIZIN UND PARASITOLOGIE 1807 1% 1% 3
3 PHOSPHORUS SULFUR AND SILICON AND THE RELATED ELEMENTS 1675 3% 0% 17
4 BIOCHEMICAL PHARMACOLOGY 1534 4% 0% 22
5 ARCHIV DER PHARMAZIE 1371 2% 0% 10
6 JOURNAL OF IMMUNOPHARMACOLOGY 1177 0% 1% 2
7 BULLETIN DE LA SOCIETE CHIMIQUE DE FRANCE PARTIE II-CHIMIE MOLECULAIRE ORGANIQUE ET BIOLOGIQUE 746 0% 1% 2
8 CHEMICAL RESEARCH IN TOXICOLOGY 721 2% 0% 8
9 JOURNAL OF THE CHEMICAL SOCIETY-PERKIN TRANSACTIONS 2 713 2% 0% 10
10 ADVANCES IN HETEROCYCLIC CHEMISTRY 650 0% 1% 2

Author Key Words


Rank Term Chi square Shr. of publ. in
class containing
term		 Class's shr. of
term's tot. occurrences		 #P with
term in
class		 LCSH search Wikipedia search
1 OLTIPRAZ 1149891 7% 52% 37 Search OLTIPRAZ Search OLTIPRAZ
2 1 2 DITHIOLE 3 THIONES 717633 4% 63% 19 Search 1+2+DITHIOLE+3+THIONES Search 1+2+DITHIOLE+3+THIONES
3 DITHIOLETHIONES 603822 4% 56% 18 Search DITHIOLETHIONES Search DITHIOLETHIONES
4 METAL CYCLOPENTADIENIDES 178915 1% 100% 3 Search METAL+CYCLOPENTADIENIDES Search METAL+CYCLOPENTADIENIDES
5 CANCER PREVENTION EFFICACY 134185 1% 75% 3 Search CANCER+PREVENTION+EFFICACY Search CANCER+PREVENTION+EFFICACY
6 INVOLUCRIN EXPRESSION 134185 1% 75% 3 Search INVOLUCRIN+EXPRESSION Search INVOLUCRIN+EXPRESSION
7 1 2 DITHIOLE 3 ONES 119277 0% 100% 2 Search 1+2+DITHIOLE+3+ONES Search 1+2+DITHIOLE+3+ONES
8 3 7 DITHIATRICYCLO44002 8DECA 4 9 DIENE 119277 0% 100% 2 Search 3+7+DITHIATRICYCLO44002+8DECA+4+9+DIENE Search 3+7+DITHIATRICYCLO44002+8DECA+4+9+DIENE
9 3 IMINO 1 2 DITHIOLE 119277 0% 100% 2 Search 3+IMINO+1+2+DITHIOLE Search 3+IMINO+1+2+DITHIOLE
10 4 HYDROXY ANETHOLE TRITHIONE 119277 0% 100% 2 Search 4+HYDROXY+ANETHOLE+TRITHIONE Search 4+HYDROXY+ANETHOLE+TRITHIONE

Core articles
The table includes core articles in the class. The following variables is taken into account for the relevance score of an article in a cluster c:
(1) Number of references referring to publications in the class.
(2) Share of total number of active references referring to publications in the class.
(3) Age of the article. New articles get higher score than old articles.
(4) Citation rate, normalized to year.


Rank Reference # ref.
in cl.		 Shr. of ref. in
cl.		 Citations
1 FISCHER, G , (2013) RECENT PROGRESS IN 1,2-DITHIOLE-3-THIONE CHEMISTRY.ADVANCES IN HETEROCYCLIC CHEMISTRY, VOL 109. VOL. 109. ISSUE . P. 1-90 98 57% 5
2 ZHANG, YS , MUNDAY, R , (2008) DITHIOLETHIONES FOR CANCER CHEMOPREVENTION: WHERE DO WE STAND?.MOLECULAR CANCER THERAPEUTICS. VOL. 7. ISSUE 11. P. 3470-3479 54 59% 48
3 CLAPPER, ML , (1998) CHEMOPREVENTIVE ACTIVITY OF OLTIPRAZ.PHARMACOLOGY & THERAPEUTICS. VOL. 78. ISSUE 1. P. 17-27 36 72% 69
4 BROOKS, SC , BROOKS, JS , LEE, WH , LEE, MG , KIM, SG , (2009) THERAPEUTIC POTENTIAL OF DITHIOLETHIONES FOR HEPATIC DISEASES.PHARMACOLOGY & THERAPEUTICS. VOL. 124. ISSUE 1. P. 31-43 41 30% 16
5 HADJADJ, M , DADAMOUSSA, B , ABASQ, ML , SAIDI, M , BURGOT, JL , DARCHEN, A , (2010) RADICAL SCAVENGER PROPERTIES OF SOME 1,2-DITHIOL COMPOUNDS AGAINST ELECTROPOLYMERIZATION OF ANILINE.ASIAN JOURNAL OF CHEMISTRY. VOL. 22. ISSUE 1. P. 501-511 22 55% 1
6 VELAYUTHAM, M , VILLAMENA, FA , FISHBEIN, JC , ZWEIER, JL , (2005) CANCER CHEMOPREVENTIVE OLTIPRAZ GENERATES SUPEROXIDE ANION RADICAL.ARCHIVES OF BIOCHEMISTRY AND BIOPHYSICS. VOL. 435. ISSUE 1. P. 83-88 23 52% 17
7 KENSLER, TW , GROOPMAN, JD , SUTTER, TR , CURPHEY, TJ , ROEBUCK, BD , (1999) DEVELOPMENT OF CANCER CHEMOPREVENTIVE AGENTS: OLTIPRAZ AS A PARADIGM.CHEMICAL RESEARCH IN TOXICOLOGY. VOL. 12. ISSUE 2. P. 113 -126 33 38% 112
8 BENSON, AB , OLOPADE, OI , RATAIN, MJ , RADEMAKER, A , MOBARHAN, S , STUCKY-MARSHALL, L , FRENCH, S , DOLAN, ME , (2000) CHRONIC DAILY LOW DOSE OF 4-METHYL-5-(2-PYRAZINYL)-1,2-DITHIOLE-3-THIONE (OLTIPRAZ) IN PATIENTS WITH PREVIOUSLY RESECTED COLON POLYPS AND FIRST-DEGREE FEMALE RELATIVES OF BREAST CANCER PATIENTS.CLINICAL CANCER RESEARCH. VOL. 6. ISSUE 10. P. 3870 -3877 20 69% 12
9 VELAYUTHAM, M , VILLAMENA, FA , NAVAMAL, M , FISHBEIN, JC , ZWEIER, JL , (2005) GLUTATHIONE-MEDIATED FORMATION OF OXYGEN FREE RADICALS BY THE MAJOR METABOLITE OF OLTIPRAZ.CHEMICAL RESEARCH IN TOXICOLOGY. VOL. 18. ISSUE 6. P. 970-975 22 52% 18
10 PETZER, JP , NAVAMAL, M , JOHNSON, JK , KWAK, MK , KENSLER, TW , FISHBEIN, JC , (2003) PHASE 2 ENZYME INDUCTION BY THE MAJOR METABOLITE OF OLTIPRAZ.CHEMICAL RESEARCH IN TOXICOLOGY. VOL. 16. ISSUE 11. P. 1463-1469 20 59% 18

Classes with closest relation at Level 1


Rank Class id link
1 8144 AFLATOXIN B 1//AFLATOXIN//AFLATOXIN ALBUMIN ADDUCTS
2 17643 ASAN FDN//AGROPHARMA//DA 125
3 14978 LEINAMYCIN//TRITHIOLE//VIC DISULFOXIDE
4 1613 NRF2//KEAP1//ANTIOXIDANT RESPONSE ELEMENT
5 29591 FISCHER TYPE CARBENE COMPLEXES//1 2 DITHIOLO4 3 BTHIOPYRAN//1 2 DITHIOLO4 3 C1 2 DITHIOLE
6 36808 TAERIM CENT//PARA CHLORO META XYLENOL PCMX//4 CHLORO 3 5 DIMETHYLPHENOL PCMX
7 30124 1 2 DITHIIN//1 1 3 3 TETRAMETHYLLEUCOISOINDIGO//1 2 ACETYLENEDITHIOL
8 8735 PRAZIQUANTEL//SCHISTOSOMA MANSONI//OXAMNIQUINE
9 35529 CHRONIC SEPTICEMIC SALMONELLOSIS//INNERE MED FMH//INTERNAL MED INFECT DIS RUE HAUTE 322
10 30459 PLANT PROTECTING COMPOUNDS//THIAZOL 2 THIONE//1 3 DITHIANC

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