Class information for:
Level 1: LYSOSOMAL ACID LIPASE//CHOLESTERYL ESTER STORAGE DISEASE//WOLMAN DISEASE

Basic class information
Class id #P Avg. number of
references		 Database coverage
of references
19487 503 27.7 49%


Bar chart of Publication_year

Last years might be incomplete

Hierarchy of classes
The table includes all classes above and classes immediately below the current class.


Cluster id Level Cluster label #P
5 4 CHEMISTRY, ORGANIC//CHEMISTRY, INORGANIC & NUCLEAR//CHEMISTRY, MULTIDISCIPLINARY 1745167
239 3       LIPASE//JOURNAL OF MOLECULAR CATALYSIS B-ENZYMATIC//BIOCATALYSIS 47598
2176 2             LIPASE//UPR 9025//COLIPASE 4953
19487 1                   LYSOSOMAL ACID LIPASE//CHOLESTERYL ESTER STORAGE DISEASE//WOLMAN DISEASE 503

Terms with highest relevance score


rank Term termType Chi square Shr. of publ. in
class containing
term		 Class's shr. of
term's tot. occurrences		 #P with
term in
class
1 LYSOSOMAL ACID LIPASE authKW 2352584 9% 82% 47
2 CHOLESTERYL ESTER STORAGE DISEASE authKW 2065668 7% 97% 35
3 WOLMAN DISEASE authKW 1992231 8% 86% 38
4 CHOLESTEROL ESTER STORAGE DISEASE authKW 667759 2% 100% 11
5 LYSOSOMAL ACID LIPASE DEFICIENCY authKW 667759 2% 100% 11
6 ACID LIPASE authKW 303517 2% 50% 10
7 CHOLESTERYL ESTER STORAGE DISEASE CESD authKW 242822 1% 100% 4
8 LAL DEFICIENCY authKW 242822 1% 100% 4
9 LYSOSOMAL ACID LIPASE LAL DEFICIENCY authKW 182116 1% 100% 3
10 WOLMAN authKW 182116 1% 100% 3

Web of Science journal categories


Rank Term Chi square Shr. of publ. in
class containing
term		 Class's shr. of
term's tot. occurrences		 #P with
term in
class
1 Biochemistry & Molecular Biology 709 33% 0% 168
2 Medicine, Research & Experimental 486 13% 0% 63
3 Genetics & Heredity 403 13% 0% 65
4 Biophysics 283 10% 0% 48
5 Nutrition & Dietetics 259 7% 0% 33
6 Medical Laboratory Technology 229 4% 0% 19
7 Gastroenterology & Hepatology 213 7% 0% 35
8 Pathology 207 6% 0% 32
9 Pediatrics 186 8% 0% 38
10 Endocrinology & Metabolism 129 7% 0% 37

Address terms


Rank Term Chi square Shr. of publ. in
class containing
term		 Class's shr. of
term's tot. occurrences		 #P with
term in
class
1 ARTERIOSCLEROSIS SPECIALIZED 121411 0% 100% 2
2 IU SIMON CANC 94835 2% 16% 10
3 MED HLTH SCI NUTR 80939 0% 67% 2
4 ABT AUXOL 60705 0% 100% 1
5 BASIC MED SCI MOL LIFE SCI 60705 0% 100% 1
6 CARDIOL EOS 60705 0% 100% 1
7 CORE CLIN PATHOL 60705 0% 100% 1
8 EDINBURGH SICK CHILDRENS NHS TRUST 60705 0% 100% 1
9 ENDOCRINOL METAB JPK 60705 0% 100% 1
10 ENFANTS MALADES IMAGINE 60705 0% 100% 1

Journals


Rank Term Chi square Shr. of publ. in
class containing
term		 Class's shr. of
term's tot. occurrences		 #P with
term in
class
1 JOURNAL OF INHERITED METABOLIC DISEASE 3412 3% 0% 16
2 BIOMEDICINE EXPRESS 2126 0% 2% 2
3 ENZYME 2003 1% 1% 5
4 LIPIDS 2001 3% 0% 14
5 BIOCHIMICA ET BIOPHYSICA ACTA 2000 6% 0% 31
6 JOURNAL OF LIPID RESEARCH 1804 3% 0% 16
7 MOLECULAR GENETICS AND METABOLISM 1562 2% 0% 9
8 BIOCHEMICAL MEDICINE 1063 1% 1% 3
9 NUTRITION AND METABOLISM 1063 0% 2% 1
10 VOPROSY MEDITSINSKOI KHIMII 939 1% 0% 6

Author Key Words


Rank Term Chi square Shr. of publ. in
class containing
term		 Class's shr. of
term's tot. occurrences		 #P with
term in
class		 LCSH search Wikipedia search
1 LYSOSOMAL ACID LIPASE 2352584 9% 82% 47 Search LYSOSOMAL+ACID+LIPASE Search LYSOSOMAL+ACID+LIPASE
2 CHOLESTERYL ESTER STORAGE DISEASE 2065668 7% 97% 35 Search CHOLESTERYL+ESTER+STORAGE+DISEASE Search CHOLESTERYL+ESTER+STORAGE+DISEASE
3 WOLMAN DISEASE 1992231 8% 86% 38 Search WOLMAN+DISEASE Search WOLMAN+DISEASE
4 CHOLESTEROL ESTER STORAGE DISEASE 667759 2% 100% 11 Search CHOLESTEROL+ESTER+STORAGE+DISEASE Search CHOLESTEROL+ESTER+STORAGE+DISEASE
5 LYSOSOMAL ACID LIPASE DEFICIENCY 667759 2% 100% 11 Search LYSOSOMAL+ACID+LIPASE+DEFICIENCY Search LYSOSOMAL+ACID+LIPASE+DEFICIENCY
6 ACID LIPASE 303517 2% 50% 10 Search ACID+LIPASE Search ACID+LIPASE
7 CHOLESTERYL ESTER STORAGE DISEASE CESD 242822 1% 100% 4 Search CHOLESTERYL+ESTER+STORAGE+DISEASE+CESD Search CHOLESTERYL+ESTER+STORAGE+DISEASE+CESD
8 LAL DEFICIENCY 242822 1% 100% 4 Search LAL+DEFICIENCY Search LAL+DEFICIENCY
9 LYSOSOMAL ACID LIPASE LAL DEFICIENCY 182116 1% 100% 3 Search LYSOSOMAL+ACID+LIPASE+LAL+DEFICIENCY Search LYSOSOMAL+ACID+LIPASE+LAL+DEFICIENCY
10 WOLMAN 182116 1% 100% 3 Search WOLMAN Search WOLMAN

Core articles
The table includes core articles in the class. The following variables is taken into account for the relevance score of an article in a cluster c:
(1) Number of references referring to publications in the class.
(2) Share of total number of active references referring to publications in the class.
(3) Age of the article. New articles get higher score than old articles.
(4) Citation rate, normalized to year.


Rank Reference # ref.
in cl.		 Shr. of ref. in
cl.		 Citations
1 BERNSTEIN, DL , HULKOVA, H , BIALER, MG , DESNICK, RJ , (2013) CHOLESTERYL ESTER STORAGE DISEASE: REVIEW OF THE FINDINGS IN 135 REPORTED PATIENTS WITH AN UNDERDIAGNOSED DISEASE.JOURNAL OF HEPATOLOGY. VOL. 58. ISSUE 6. P. 1230-1243 80 90% 46
2 REYNOLDS, T , (2013) CHOLESTERYL ESTER STORAGE DISEASE: A RARE AND POSSIBLY TREATABLE CAUSE OF PREMATURE VASCULAR DISEASE AND CIRRHOSIS.JOURNAL OF CLINICAL PATHOLOGY. VOL. 66. ISSUE 11. P. 918-923 63 93% 7
3 REINER, Z , GUARDAMAGNA, O , NAIR, D , SORAN, H , HOVINGH, K , BERTOLINI, S , JONES, S , CORIC, M , CALANDRA, S , HAMILTON, J , ET AL (2014) LYSOSOMAL ACID LIPASE DEFICIENCY - AN UNDER-RECOGNIZED CAUSE OF DYSLIPIDAEMIA AND LIVER DYSFUNCTION.ATHEROSCLEROSIS. VOL. 235. ISSUE 1. P. 21 -30 42 66% 32
4 PORTO, AF , (2014) LYSOSOMAL ACID LIPASE DEFICIENCY: DIAGNOSIS AND TREATMENT OF WOLMAN AND CHOLESTERYL ESTER STORAGE DISEASES.PEDIATRIC ENDOCRINOLOGY REVIEWS PER. VOL. 12. ISSUE . P. 125 -132 33 89% 5
5 CHATRATH, H , KEILIN, S , ATTAR, BM , (2009) CHOLESTEROL ESTER STORAGE DISEASE (CESD) DIAGNOSED IN AN ASYMPTOMATIC ADULT.DIGESTIVE DISEASES AND SCIENCES. VOL. 54. ISSUE 1. P. 168 -173 28 100% 6
6 FASANO, T , PISCIOTTA, L , BOCCHI, L , GUARDAMAGNA, O , ASSANDRO, P , RABACCHI, C , ZANONI, P , FILOCAMO, M , BERTOLINI, S , CALANDRA, S , (2012) LYSOSOMAL LIPASE DEFICIENCY: MOLECULAR CHARACTERIZATION OF ELEVEN PATIENTS WITH WOLMAN OR CHOLESTERYL ESTER STORAGE DISEASE.MOLECULAR GENETICS AND METABOLISM. VOL. 105. ISSUE 3. P. 450 -456 23 96% 8
7 SCOTT, SA , LIU, B , NAZARENKO, I , MARTIS, S , KOZLITINA, J , YANG, Y , RAMIREZ, C , KASAI, Y , HYATT, T , PETER, I , ET AL (2013) FREQUENCY OF THE CHOLESTERYL ESTER STORAGE DISEASE COMMON LIPA E8SJM MUTATION (C.894G > A) IN VARIOUS RACIAL AND ETHNIC GROUPS.HEPATOLOGY. VOL. 58. ISSUE 3. P. 958-965 27 75% 14
8 KURANOBU, N , MURAKAMI, J , OKAMOTO, K , NISHIMURA, R , MURAYAMA, K , TAKAMURA, A , UMEDA, T , ETO, Y , KANZAKI, S , (2016) CHOLESTEROL ESTER STORAGE DISEASE WITH A NOVEL LIPA MUTATION (L264P) THAT PRESENTED MASSIVE HEPATOMEGALY: A CASE REPORT.HEPATOLOGY RESEARCH. VOL. 46. ISSUE 5. P. 477 -482 20 95% 0
9 PATON, DM , (2016) SEBELIPASE ALFA: ENZYMATIC REPLACEMENT TREATMENT FOR LYSOSOMAL ACID LIPASE DEFICIENCY.DRUGS OF TODAY. VOL. 52. ISSUE 5. P. 287 -293 17 100% 1
10 RAJAMOHAN, F , REYES, AR , RUANGSIRILUK, W , HOTH, LR , HAN, S , CASPERS, N , TU, MH , WARD, J , KURUMBAIL, RG , (2015) EXPRESSION AND FUNCTIONAL CHARACTERIZATION OF HUMAN LYSOSOMAL ACID LIPASE GENE (LIPA) MUTATION RESPONSIBLE FOR CHOLESTERYL ESTER STORAGE DISEASE (CESD) PHENOTYPE.PROTEIN EXPRESSION AND PURIFICATION. VOL. 110. ISSUE . P. 22 -29 22 81% 0

Classes with closest relation at Level 1


Rank Class id link
1 10312 ARTERIOSCLEROSIS//PATOCYTOSIS//SPECIALIZED ATHEROSCLEROSIS
2 19790 BILE SALT DEPENDENT LIPASE//CARBAMATE INHIBITORS//BILE SALT STIMULATED LIPASE
3 36274 FATTY LIVER HEMORRHAGIC SYNDROME//ANIM DIS DISGNOST//FATTY LIVER DISORDER
4 6069 NIEMANN PICK DISEASE TYPE C//NIEMANN PICK TYPE C//NIEMANN PICK DISEASE
5 10937 COLIPASE//UPR 9025//ENTEROSTATIN
6 12318 ACAT INHIBITOR//ACYL COA CHOLESTEROL ACYLTRANSFERASE//ACAT
7 30893 LIPID ABSORPTION//ABSORPTION LYMPH AND BLOOD//ACYLGLYCEROL ACYLTRANSFERASE
8 23088 SPIROPLASMA FLORICOLA//ALBUMIN FRACTION V//ATPASE NA MG2
9 29415 LYSOSOMAL EXOGLYCOSIDASES//GEN SURG ENDOCRINOL 1//N ACETYL BETA HEXOSAMINIDASE
10 23934 MEROCYANINE 540//MEROCYANINE 540 MC540//MERODANTOIN

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