Class information for:
Level 1: EXCITATION CONTRACTION COUPLING//CATECHOLAMINERGIC POLYMORPHIC VENTRICULAR TACHYCARDIA//T TUBULES

Basic class information
Class id #P Avg. number of
references		 Database coverage
of references
2008 2389 44.6 88%


Bar chart of Publication_year

Last years might be incomplete

Hierarchy of classes
The table includes all classes above and classes immediately below the current class.


Cluster id Level Cluster label #P
8 4 CARDIAC & CARDIOVASCULAR SYSTEM//PERIPHERAL VASCULAR DISEASES//CARDIOL 1276458
11 3       ATRIAL FIBRILLATION//CARDIAC & CARDIOVASCULAR SYSTEM//CATHETER ABLATION 130936
1393 2             RYANODINE RECEPTOR//EXCITATION CONTRACTION COUPLING//SARCOPLASMIC RETICULUM 8118
2008 1                   EXCITATION CONTRACTION COUPLING//CATECHOLAMINERGIC POLYMORPHIC VENTRICULAR TACHYCARDIA//T TUBULES 2389

Terms with highest relevance score


rank Term termType Chi square Shr. of publ. in
class containing
term		 Class's shr. of
term's tot. occurrences		 #P with
term in
class
1 EXCITATION CONTRACTION COUPLING authKW 621422 11% 19% 258
2 CATECHOLAMINERGIC POLYMORPHIC VENTRICULAR TACHYCARDIA authKW 552911 3% 58% 75
3 T TUBULES authKW 542505 3% 54% 79
4 RYANODINE RECEPTOR authKW 518617 11% 15% 265
5 SARCOPLASMIC RETICULUM authKW 450794 12% 12% 283
6 UNIT CARDIAC PHYSIOL address 323450 2% 56% 45
7 CA2 SPARKS authKW 318455 2% 46% 54
8 CPVT authKW 263786 1% 61% 34
9 CA2 WAVES authKW 176284 2% 32% 43
10 JTV 519 authKW 169141 1% 88% 15

Web of Science journal categories


Rank Term Chi square Shr. of publ. in
class containing
term		 Class's shr. of
term's tot. occurrences		 #P with term
in class
1 Cardiac & Cardiovascular System 27253 42% 0% 1004
2 Physiology 16101 29% 0% 682
3 Peripheral Vascular Diseases 8847 18% 0% 437
4 Biophysics 2513 13% 0% 301
5 Cell Biology 2221 17% 0% 409
6 Hematology 1861 9% 0% 220
7 Neurosciences 328 9% 0% 224
8 Biochemistry & Molecular Biology 121 11% 0% 258
9 Pharmacology & Pharmacy 38 5% 0% 124
10 Medicine, Research & Experimental 37 3% 0% 65

Address terms


Rank Term Chi square Shr. of publ. in
class containing
term		 Class's shr. of
term's tot. occurrences		 #P with
term in
class
1 UNIT CARDIAC PHYSIOL 323450 2% 56% 45
2 MOL BIOPHYS PHYSIOL 71609 2% 12% 45
3 CLYDE HELEN WU MOL CARDIOL 65332 1% 34% 15
4 ABT KARDIOL PNEUMOL HERZZENTRUM 40894 0% 80% 4
5 CARDIOVASC BIOINFORMAT MODELING 39923 0% 31% 10
6 DAVIS HEART LUNG 505 38340 0% 100% 3
7 CLIN CARDIOL PULMONOL 35384 0% 46% 6
8 DEUT ZENTRUM HERZKREISLAUFFOR 34077 0% 67% 4
9 MOL PHYSIOL BIOPHYS MED CARDIOL 34077 0% 67% 4
10 PHYSIOL CELL BIOL MED 29208 0% 57% 4

Journals


Rank Term Chi square Shr. of publ. in
class containing
term		 Class's shr. of
term's tot. occurrences		 #P with
term in
class
1 CIRCULATION RESEARCH 51110 8% 2% 201
2 JOURNAL OF MOLECULAR AND CELLULAR CARDIOLOGY 44820 6% 2% 151
3 CARDIOVASCULAR RESEARCH 28818 6% 2% 133
4 JOURNAL OF PHYSIOLOGY-LONDON 26687 8% 1% 196
5 BIOPHYSICAL JOURNAL 19028 7% 1% 171
6 CELL CALCIUM 18236 3% 2% 64
7 AMERICAN JOURNAL OF PHYSIOLOGY-HEART AND CIRCULATORY PHYSIOLOGY 12334 5% 1% 110
8 HEART RHYTHM 6919 2% 1% 40
9 JOURNAL OF GENERAL PHYSIOLOGY 6116 2% 1% 40
10 PROGRESS IN BIOPHYSICS & MOLECULAR BIOLOGY 4797 1% 2% 21

Author Key Words


Rank Term Chi square Shr. of publ. in
class containing
term		 Class's shr. of
term's tot. occurrences		 #P with
term in
class		 LCSH search Wikipedia search
1 EXCITATION CONTRACTION COUPLING 621422 11% 19% 258 Search EXCITATION+CONTRACTION+COUPLING Search EXCITATION+CONTRACTION+COUPLING
2 CATECHOLAMINERGIC POLYMORPHIC VENTRICULAR TACHYCARDIA 552911 3% 58% 75 Search CATECHOLAMINERGIC+POLYMORPHIC+VENTRICULAR+TACHYCARDIA Search CATECHOLAMINERGIC+POLYMORPHIC+VENTRICULAR+TACHYCARDIA
3 T TUBULES 542505 3% 54% 79 Search T+TUBULES Search T+TUBULES
4 RYANODINE RECEPTOR 518617 11% 15% 265 Search RYANODINE+RECEPTOR Search RYANODINE+RECEPTOR
5 SARCOPLASMIC RETICULUM 450794 12% 12% 283 Search SARCOPLASMIC+RETICULUM Search SARCOPLASMIC+RETICULUM
6 CA2 SPARKS 318455 2% 46% 54 Search CA2+SPARKS Search CA2+SPARKS
7 CPVT 263786 1% 61% 34 Search CPVT Search CPVT
8 CA2 WAVES 176284 2% 32% 43 Search CA2+WAVES Search CA2+WAVES
9 JTV 519 169141 1% 88% 15 Search JTV+519 Search JTV+519
10 JUNCTOPHILIN 2 143983 1% 87% 13 Search JUNCTOPHILIN+2 Search JUNCTOPHILIN+2

Core articles
The table includes core articles in the class. The following variables is taken into account for the relevance score of an article in a cluster c:
(1) Number of references referring to publications in the class.
(2) Share of total number of active references referring to publications in the class.
(3) Age of the article. New articles get higher score than old articles.
(4) Citation rate, normalized to year.


Rank Reference # ref. in
cl.		 Shr. of ref. in
cl.		 Citations
1 BERS, DM , (2014) CARDIAC SARCOPLASMIC RETICULUM CALCIUM LEAK: BASIS AND ROLES IN CARDIAC DYSFUNCTION.ANNUAL REVIEW OF PHYSIOLOGY, VOL 76. VOL. 76. ISSUE . P. 107 -127 101 81% 46
2 PRIORI, SG , CHEN, SRW , (2011) INHERITED DYSFUNCTION OF SARCOPLASMIC RETICULUM CA2+ HANDLING AND ARRHYTHMOGENESIS.CIRCULATION RESEARCH. VOL. 108. ISSUE 7. P. 871 -883 76 79% 124
3 BLAYNEY, LM , LAI, FA , (2009) RYANODINE RECEPTOR-MEDIATED ARRHYTHMIAS AND SUDDEN CARDIAC DEATH.PHARMACOLOGY & THERAPEUTICS. VOL. 123. ISSUE 2. P. 151-177 176 43% 43
4 CHENG, HP , LEDERER, WJ , (2008) CALCIUM SPARKS.PHYSIOLOGICAL REVIEWS. VOL. 88. ISSUE 4. P. 1491 -1545 151 38% 246
5 SOBIE, EA , LEDERER, WJ , (2012) DYNAMIC LOCAL CHANGES IN SARCOPLASMIC RETICULUM CALCIUM: PHYSIOLOGICAL AND PATHOPHYSIOLOGICAL ROLES.JOURNAL OF MOLECULAR AND CELLULAR CARDIOLOGY. VOL. 52. ISSUE 2. P. 304 -311 79 84% 24
6 CANNELL, MB , KONG, CHT , (2012) LOCAL CONTROL IN CARDIAC E-C COUPLING.JOURNAL OF MOLECULAR AND CELLULAR CARDIOLOGY. VOL. 52. ISSUE 2. P. 298 -303 82 78% 22
7 WALKER, MA , WILLIAMS, GSB , KOHL, T , LEHNART, SE , JAFRI, MS , GREENSTEIN, JL , LEDERER, WJ , WINSLOW, RL , (2014) SUPERRESOLUTION MODELING OF CALCIUM RELEASE IN THE HEART.BIOPHYSICAL JOURNAL. VOL. 107. ISSUE 12. P. 3009 -3020 74 84% 6
8 POLAKOVA, E , SOBIE, EA , (2013) ALTERATIONS IN T-TUBULE AND DYAD STRUCTURE IN HEART DISEASE: CHALLENGES AND OPPORTUNITIES FOR COMPUTATIONAL ANALYSES.CARDIOVASCULAR RESEARCH. VOL. 98. ISSUE 2. P. 233-239 70 91% 5
9 SALAZAR-CANTU, A , PEREZ-TREVINO, P , MONTALVO-PARRA, D , BALDERAS-VILLALOBOS, J , GOMEZ-VIQUEZ, NL , GARCIA, N , ALTAMIRANO, J , (2016) ROLE OF SERCA AND THE SARCOPLASMIC RETICULUM CALCIUM CONTENT ON CALCIUM WAVES PROPAGATION IN RAT VENTRICULAR MYOCYTES.ARCHIVES OF BIOCHEMISTRY AND BIOPHYSICS. VOL. 604. ISSUE . P. 11 -19 67 84% 1
10 CURRIE, S , ELLIOTT, EB , SMITH, GL , LOUGHREY, CM , (2011) TWO CANDIDATES AT THE HEART OF DYSFUNCTION: THE RYANODINE RECEPTOR AND CALCIUM/CALMODULIN PROTEIN KINASE II AS POTENTIAL TARGETS FOR THERAPEUTIC INTERVENTION-AN IN VIVO PERSPECTIVE.PHARMACOLOGY & THERAPEUTICS. VOL. 131. ISSUE 2. P. 204 -220 94 66% 19

Classes with closest relation at Level 1


Rank Class id link
1 2601 RYANODINE RECEPTOR//CALSEQUESTRIN//SARCOPLASMIC RETICULUM
2 3746 PHOSPHOLAMBAN//SARCOPLASMIC RETICULUM//PHARMACOL CELL BIOPHYS
3 7174 R 56865//DELAYED AFTERDEPOLARIZATION//DIASTOLIC DEPOLARIZATION
4 5537 NA CA2 EXCHANGER//NCX//SODIUM CALCIUM EXCHANGER
5 18583 RANOLAZINE//LATE SODIUM CURRENT//LATE I NA
6 34550 CPU 86017//CPU0213//ARGIREIN
7 6529 T WAVE ALTERNANS//ALTERNANS//MICROVOLT T WAVE ALTERNANS
8 7026 TRANSIENT OUTWARD CURRENT//KV43//KCHIP
9 5929 CALCIUM SIGNALS//TIMOTHY SYNDROME//CAV12
10 6296 EXCITATION CONTRACTION COUPLING//JOURNAL OF GENERAL PHYSIOLOGY//MAMMALIAN SKELETAL MUSCLE

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