Class information for:
Level 1: BIOORGAN MED CHEM//OPTICALLY ACTIVE ANTIFUNGAL AZOLE//CYP51

Basic class information
Class id #P Avg. number of
references		 Database coverage
of references
20089 477 33.5 71%


Bar chart of Publication_year

Last years might be incomplete

Hierarchy of classes
The table includes all classes above and classes immediately below the current class.


Cluster id Level Cluster label #P
7 4 INFECTIOUS DISEASES//MICROBIOLOGY//VIROLOGY 1353914
156 3       MYCOSES//MYCOLOGY//CANDIDA ALBICANS 62026
1247 2             ONYCHOMYCOSIS//DERMATOPHYTES//DERMATOPHYTOSIS 8986
20089 1                   BIOORGAN MED CHEM//OPTICALLY ACTIVE ANTIFUNGAL AZOLE//CYP51 477

Terms with highest relevance score


rank Term termType Chi square Shr. of publ. in
class containing
term		 Class's shr. of
term's tot. occurrences		 #P with
term in
class
1 BIOORGAN MED CHEM address 698927 10% 23% 48
2 OPTICALLY ACTIVE ANTIFUNGAL AZOLE authKW 576130 2% 100% 9
3 CYP51 authKW 373816 6% 20% 29
4 1 2 3 TRISUBSTITUTED 2 BUTANOL authKW 320072 1% 100% 5
5 CS 758 authKW 256058 1% 100% 4
6 CYP51 INHIBITORS authKW 256058 1% 100% 4
7 AZOLE ANTIFUNGALS authKW 202346 3% 23% 14
8 ER 30346 authKW 192043 1% 100% 3
9 LANOSTEROL 14 ALPHA DEMETHYLASE CYP51 authKW 192043 1% 100% 3
10 MED CHEM S HIROMACHI SHINAGAWA KU address 192043 1% 100% 3

Web of Science journal categories


Rank Term Chi square Shr. of publ. in
class containing
term		 Class's shr. of
term's tot. occurrences		 #P with
term in
class
1 Chemistry, Medicinal 12217 47% 0% 225
2 Chemistry, Organic 1310 25% 0% 117
3 Pharmacology & Pharmacy 536 21% 0% 102
4 Chemistry, Multidisciplinary 530 23% 0% 112
5 Crystallography 212 6% 0% 30
6 Mycology 35 1% 0% 6
7 Biochemistry & Molecular Biology 20 10% 0% 49
8 Infectious Diseases 16 3% 0% 12
9 Microbiology 5 3% 0% 14
10 Computer Science, Interdisciplinary Applications 4 1% 0% 7

Address terms


Rank Term Chi square Shr. of publ. in
class containing
term		 Class's shr. of
term's tot. occurrences		 #P with
term in
class
1 BIOORGAN MED CHEM 698927 10% 23% 48
2 MED CHEM S HIROMACHI SHINAGAWA KU 192043 1% 100% 3
3 PHARM TEAM 144031 1% 75% 3
4 COMPUTAT BIO BIOINFORMAT 128029 0% 100% 2
5 YANGJI RD 128029 0% 100% 2
6 OVERSEAS EDUC 109730 1% 29% 6
7 PL CHEM CHONGQING MUNICIPAL 108138 3% 12% 14
8 QINGHAI AGR FO TRY 96019 1% 50% 3
9 MED CHEM S 2 82533 1% 18% 7
10 MIL MED CHEM 82301 1% 43% 3

Journals


Rank Term Chi square Shr. of publ. in
class containing
term		 Class's shr. of
term's tot. occurrences		 #P with
term in
class
1 EUROPEAN JOURNAL OF MEDICINAL CHEMISTRY 12702 9% 0% 43
2 BIOORGANIC & MEDICINAL CHEMISTRY LETTERS 5118 9% 0% 45
3 MEDCHEMCOMM 4729 2% 1% 10
4 ARCHIV DER PHARMAZIE 3328 3% 0% 15
5 CHEMICAL & PHARMACEUTICAL BULLETIN 2678 6% 0% 27
6 CHEMICAL BIOLOGY & DRUG DESIGN 2469 2% 0% 8
7 FARMACO 1781 1% 0% 7
8 CHINESE CHEMICAL LETTERS 1716 3% 0% 15
9 MEDICINAL CHEMISTRY RESEARCH 1619 2% 0% 9
10 JOURNAL OF MEDICINAL CHEMISTRY 941 4% 0% 18

Author Key Words


Rank Term Chi square Shr. of publ. in
class containing
term		 Class's shr. of
term's tot. occurrences		 #P with
term in
class		 LCSH search Wikipedia search
1 OPTICALLY ACTIVE ANTIFUNGAL AZOLE 576130 2% 100% 9 Search OPTICALLY+ACTIVE+ANTIFUNGAL+AZOLE Search OPTICALLY+ACTIVE+ANTIFUNGAL+AZOLE
2 CYP51 373816 6% 20% 29 Search CYP51 Search CYP51
3 1 2 3 TRISUBSTITUTED 2 BUTANOL 320072 1% 100% 5 Search 1+2+3+TRISUBSTITUTED+2+BUTANOL Search 1+2+3+TRISUBSTITUTED+2+BUTANOL
4 CS 758 256058 1% 100% 4 Search CS+758 Search CS+758
5 CYP51 INHIBITORS 256058 1% 100% 4 Search CYP51+INHIBITORS Search CYP51+INHIBITORS
6 AZOLE ANTIFUNGALS 202346 3% 23% 14 Search AZOLE+ANTIFUNGALS Search AZOLE+ANTIFUNGALS
7 ER 30346 192043 1% 100% 3 Search ER+30346 Search ER+30346
8 LANOSTEROL 14 ALPHA DEMETHYLASE CYP51 192043 1% 100% 3 Search LANOSTEROL+14+ALPHA+DEMETHYLASE+CYP51 Search LANOSTEROL+14+ALPHA+DEMETHYLASE+CYP51
9 TAK 456 192043 1% 100% 3 Search TAK+456 Search TAK+456
10 IODICONAZOLE 170702 1% 67% 4 Search IODICONAZOLE Search IODICONAZOLE

Core articles
The table includes core articles in the class. The following variables is taken into account for the relevance score of an article in a cluster c:
(1) Number of references referring to publications in the class.
(2) Share of total number of active references referring to publications in the class.
(3) Age of the article. New articles get higher score than old articles.
(4) Citation rate, normalized to year.


Rank Reference # ref.
in cl.		 Shr. of ref. in
cl.		 Citations
1 WU, SC , ZHANG, YQ , HE, XM , CHE, XY , WANG, SZ , LIU, Y , JIANG, Y , LIU, N , DONG, GQ , YAO, JZ , ET AL (2014) FROM ANTIDIABETIC TO ANTIFUNGAL: DISCOVERY OF HIGHLY POTENT TRIAZOLE-THIAZOLIDINEDIONE HYBRIDS AS NOVEL ANTIFUNGAL AGENTS.CHEMMEDCHEM. VOL. 9. ISSUE 12. P. 2639 -2646 29 78% 1
2 JIANG, ZG , GU, JL , WANG, C , WANG, SZ , LIU, N , JIANG, Y , DONG, GQ , WANG, Y , LIU, Y , YAO, JZ , ET AL (2014) DESIGN, SYNTHESIS AND ANTIFUNGAL ACTIVITY OF NOVEL TRIAZOLE DERIVATIVES CONTAINING SUBSTITUTED 1,2,3-TRIAZOLE-PIPERDINE SIDE CHAINS.EUROPEAN JOURNAL OF MEDICINAL CHEMISTRY. VOL. 82. ISSUE . P. 490 -497 22 79% 15
3 ZHANG, L , ADDLA, D , PONMANI, J , WANG, A , XIE, D , WANG, YN , ZHANG, SL , GENG, RX , CAI, GX , LI, S , ET AL (2016) DISCOVERY OF MEMBRANE ACTIVE BENZIMIDAZOLE QUINOLONES-BASED TOPOISOMERASE INHIBITORS AS POTENTIAL DNA-BINDING ANTIMICROBIAL AGENTS.EUROPEAN JOURNAL OF MEDICINAL CHEMISTRY. VOL. 111. ISSUE . P. 160 -182 32 44% 2
4 PENG, LP , NAGARAJAN, S , RASHEED, S , ZHOU, CH , (2015) SYNTHESIS AND BIOLOGICAL EVALUATION OF A NEW CLASS OF QUINAZOLINONE AZOLES AS POTENTIAL ANTIMICROBIAL AGENTS AND THEIR INTERACTIONS WITH CALF THYMUS DNA AND HUMAN SERUM ALBUMIN.MEDCHEMCOMM. VOL. 6. ISSUE 1. P. 222 -229 29 45% 9
5 FANG, XJ , JEYAKKUMAR, P , AVULA, SR , ZHOU, Q , ZHOU, CH , (2016) DESIGN, SYNTHESIS AND BIOLOGICAL EVALUATION OF 5-FLUOROURACIL-DERIVED BENZIMIDAZOLES AS NOVEL TYPE OF POTENTIAL ANTIMICROBIAL AGENTS.BIOORGANIC & MEDICINAL CHEMISTRY LETTERS. VOL. 26. ISSUE 11. P. 2584 -2588 21 58% 2
6 BEHROUZ, S , RAD, MNS , ROSTAMI, S , BEHROUZ, M , ZAREHNEZHAD, E , ZAREHNEZHAD, A , (2014) DESIGN, SYNTHESIS, AND BIOLOGICAL ACTIVITIES OF NOVEL AZOLE-BONDED BETA-HYDROXYPROPYL OXIME O-ETHERS.MOLECULAR DIVERSITY. VOL. 18. ISSUE 4. P. 797 -808 22 63% 1
7 SHENG, CQ , CHE, XY , WANG, WY , WANG, SZ , CAO, YB , YAO, JZ , MIAO, ZY , ZHANG, WN , (2011) STRUCTURE-BASED DESIGN, SYNTHESIS, AND ANTIFUNGAL ACTIVITY OF NEW TRIAZOLE DERIVATIVES.CHEMICAL BIOLOGY & DRUG DESIGN. VOL. 78. ISSUE 2. P. 309 -313 18 78% 8
8 GONG, HH , BAATHULAA, K , LV, JS , CAI, GX , ZHOU, CH , (2016) SYNTHESIS AND BIOLOGICAL EVALUATION OF SCHIFF BASE-LINKED IMIDAZOLYL NAPHTHALIMIDES AS NOVEL POTENTIAL ANTI-MRSA AGENTS.MEDCHEMCOMM. VOL. 7. ISSUE 5. P. 924 -931 25 51% 0
9 PENG, XM , KUMAR, KV , DAMU, GL , ZHOU, CH , (2016) COUMARIN-DERIVED AZOLYL ETHANOLS: SYNTHESIS, ANTIMICROBIAL EVALUATION AND PRELIMINARY ACTION MECHANISM.SCIENCE CHINA-CHEMISTRY. VOL. 59. ISSUE 7. P. 878 -894 24 47% 0
10 ZHANG, HZ , LIN, JM , RASHEED, S , ZHOU, CH , (2014) DESIGN, SYNTHESIS, AND BIOLOGICAL EVALUATION OF NOVEL BENZIMIDAZOLE DERIVATIVES AND THEIR INTERACTION WITH CALF THYMUS DNA AND SYNERGISTIC EFFECTS WITH CLINICAL DRUGS.SCIENCE CHINA-CHEMISTRY. VOL. 57. ISSUE 6. P. 807-822 20 51% 13

Classes with closest relation at Level 1


Rank Class id link
1 36486 SORDARIN//SORDARICIN//ZOFIMARIN
2 30246 FARM IST MICROBIOL//FENTICONAZOLE NITRATE//FENTICONAZOLE
3 32316 N ADAMANTAN 2 YLIDENEBENZOHYDRAZIDE//1 ADAMANTYL DERIVATIVES//TRIPLE HYDROGEN BOND
4 6968 STEROL METHYLTRANSFERASE//STEROL C24 METHYLTRANSFERASE//ERGOSTEROL BIOSYNTHESIS
5 8371 CDR1//PDR5//PLEIOTROPIC DRUG RESISTANCE
6 5768 MICAFUNGIN//CASPOFUNGIN//ECHINOCANDINS
7 9484 FLUCONAZOLE//MICRODILUTION TEST//SUSCEPTIBILITY TESTING
8 3418 1 2 4 TRIAZOLE//TRIAZOLOTHIADIAZOLES//TRIAZOLOTHIADIAZINES
9 8574 VORICONAZOLE//POSACONAZOLE//HYDROXYITRACONAZOLE
10 17333 2 4 5 TRISUBSTITUTED IMIDAZOLES//1 2 4 5 TETRASUBSTITUTED IMIDAZOLES//TETRASUBSTITUTED IMIDAZOLES

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