Class information for:
Level 1: BACLOFEN//CGP44532//OPERANT ORAL ALCOHOL SELF ADMINISTRATION

Basic class information
Class id #P Avg. number of
references		 Database coverage
of references
22777 369 44.4 81%


Bar chart of Publication_year

Last years might be incomplete

Hierarchy of classes
The table includes all classes above and classes immediately below the current class.


Cluster id Level Cluster label #P
11 4 NEUROSCIENCES//CLINICAL NEUROLOGY//NEUROL 1112395
76 3       NEUROSCIENCES//DOPAMINE//SEROTONIN 81359
75 2             NUCLEUS ACCUMBENS//DOPAMINE//COCAINE 27976
22777 1                   BACLOFEN//CGP44532//OPERANT ORAL ALCOHOL SELF ADMINISTRATION 369

Terms with highest relevance score


rank Term termType Chi square Shr. of publ. in
class containing
term		 Class's shr. of
term's tot. occurrences		 #P with
term in
class
1 BACLOFEN authKW 970453 34% 9% 127
2 CGP44532 authKW 297898 2% 60% 6
3 OPERANT ORAL ALCOHOL SELF ADMINISTRATION authKW 264801 1% 80% 4
4 POSTSYNAPTIC DOPAMINE RECEPTOR SUPERSENSITIVITY authKW 264801 1% 80% 4
5 GABAB RECEPTOR authKW 214461 13% 6% 47
6 GAMMA VINYL GABA VIGABATRIN authKW 186188 1% 75% 3
7 POSITIVE ALLOSTERIC MODULATOR OF THE GABAB RECEPTOR GS39783 authKW 186188 1% 75% 3
8 ALCOHOL REINFORCING PROPERTIES authKW 165502 1% 100% 2
9 HIGH DOSE BACLOFEN authKW 165502 1% 100% 2
10 IN VIVO BRAIN DIALYSIS authKW 165502 1% 100% 2

Web of Science journal categories


Rank Term Chi square Shr. of publ. in
class containing
term		 Class's shr. of
term's tot. occurrences		 #P with
term in
class
1 Substance Abuse 6733 20% 0% 74
2 Pharmacology & Pharmacy 2424 47% 0% 175
3 Neurosciences 2211 45% 0% 167
4 Psychiatry 1854 26% 0% 96
5 Behavioral Sciences 719 10% 0% 38
6 Toxicology 37 4% 0% 14
7 Clinical Neurology 28 5% 0% 20
8 Psychology, Clinical 15 2% 0% 7
9 Psychology, Biological 13 1% 0% 3
10 Medicine, General & Internal 5 4% 0% 13

Address terms


Rank Term Chi square Shr. of publ. in
class containing
term		 Class's shr. of
term's tot. occurrences		 #P with
term in
class
1 CAMTEA 82751 0% 100% 1
2 CEDRE BLEU 82751 0% 100% 1
3 CERTA LALBATROSU 669 82751 0% 100% 1
4 CH DUNKERQUE 82751 0% 100% 1
5 CHIYODA KU DENT 82751 0% 100% 1
6 CHRU LE PAN 82751 0% 100% 1
7 COMITE COORDINAT TOXICOVIGILANCE 82751 0% 100% 1
8 CS A JEU PAUME 82751 0% 100% 1
9 DISPOSITIF CAMTEA 82751 0% 100% 1
10 EA SPHERE METHODS PATIENT OUTCOMES HLTH 82751 0% 100% 1

Journals


Rank Term Chi square Shr. of publ. in
class containing
term		 Class's shr. of
term's tot. occurrences		 #P with
term in
class
1 SYNAPSE 9092 5% 1% 19
2 ALCOHOL AND ALCOHOLISM 6455 4% 1% 15
3 PSYCHOPHARMACOLOGY 5746 8% 0% 29
4 DRUG AND ALCOHOL DEPENDENCE 5487 5% 0% 20
5 ALCOHOL 2569 2% 0% 9
6 PHARMACOLOGY BIOCHEMISTRY AND BEHAVIOR 2387 5% 0% 19
7 ALCOHOLISM-CLINICAL AND EXPERIMENTAL RESEARCH 2324 4% 0% 15
8 BEHAVIOURAL PHARMACOLOGY 2079 2% 0% 7
9 ADDICTION BIOLOGY 1731 1% 0% 5
10 NEUROPSYCHOPHARMACOLOGY 1309 2% 0% 9

Author Key Words


Rank Term Chi square Shr. of publ. in
class containing
term		 Class's shr. of
term's tot. occurrences		 #P with
term in
class		 LCSH search Wikipedia search
1 BACLOFEN 970453 34% 9% 127 Search BACLOFEN Search BACLOFEN
2 CGP44532 297898 2% 60% 6 Search CGP44532 Search CGP44532
3 OPERANT ORAL ALCOHOL SELF ADMINISTRATION 264801 1% 80% 4 Search OPERANT+ORAL+ALCOHOL+SELF+ADMINISTRATION Search OPERANT+ORAL+ALCOHOL+SELF+ADMINISTRATION
4 POSTSYNAPTIC DOPAMINE RECEPTOR SUPERSENSITIVITY 264801 1% 80% 4 Search POSTSYNAPTIC+DOPAMINE+RECEPTOR+SUPERSENSITIVITY Search POSTSYNAPTIC+DOPAMINE+RECEPTOR+SUPERSENSITIVITY
5 GABAB RECEPTOR 214461 13% 6% 47 Search GABAB+RECEPTOR Search GABAB+RECEPTOR
6 GAMMA VINYL GABA VIGABATRIN 186188 1% 75% 3 Search GAMMA+VINYL+GABA+VIGABATRIN Search GAMMA+VINYL+GABA+VIGABATRIN
7 POSITIVE ALLOSTERIC MODULATOR OF THE GABAB RECEPTOR GS39783 186188 1% 75% 3 Search POSITIVE+ALLOSTERIC+MODULATOR+OF+THE+GABAB+RECEPTOR+GS39783 Search POSITIVE+ALLOSTERIC+MODULATOR+OF+THE+GABAB+RECEPTOR+GS39783
8 ALCOHOL REINFORCING PROPERTIES 165502 1% 100% 2 Search ALCOHOL+REINFORCING+PROPERTIES Search ALCOHOL+REINFORCING+PROPERTIES
9 HIGH DOSE BACLOFEN 165502 1% 100% 2 Search HIGH+DOSE+BACLOFEN Search HIGH+DOSE+BACLOFEN
10 IN VIVO BRAIN DIALYSIS 165502 1% 100% 2 Search IN+VIVO+BRAIN+DIALYSIS Search IN+VIVO+BRAIN+DIALYSIS

Core articles
The table includes core articles in the class. The following variables is taken into account for the relevance score of an article in a cluster c:
(1) Number of references referring to publications in the class.
(2) Share of total number of active references referring to publications in the class.
(3) Age of the article. New articles get higher score than old articles.
(4) Citation rate, normalized to year.


Rank Reference # ref.
in cl.		 Shr. of ref. in
cl.		 Citations
1 AGABIO, R , PRETI, A , GESSA, GL , (2013) EFFICACY AND TOLERABILITY OF BACLOFEN IN SUBSTANCE USE DISORDERS: A SYSTEMATIC REVIEW.EUROPEAN ADDICTION RESEARCH. VOL. 19. ISSUE 6. P. 325 -345 75 51% 11
2 LORRAI, I , MACCIONI, P , GESSA, GL , COLOMBO, G , (2016) R(+)-BACLOFEN, BUT NOT S(-)-BACLOFEN, ALTERS ALCOHOL SELF-ADMINISTRATION IN ALCOHOL-PREFERRING RATS.FRONTIERS IN PSYCHIATRY. VOL. 7. ISSUE . P. - 35 81% 0
3 AGABIO, R , COLOMBO, G , (2014) GABA(B) RECEPTOR LIGANDS FOR THE TREATMENT OF ALCOHOL USE DISORDER: PRECLINICAL AND CLINICAL EVIDENCE.FRONTIERS IN NEUROSCIENCE. VOL. 8. ISSUE . P. - 48 51% 12
4 HALBOUT, B , QUARTA, D , VALERIO, E , HEIDBREDER, CA , HUTCHESON, DM , (2011) THE GABA-B POSITIVE MODULATOR GS39783 DECREASES PSYCHOSTIMULANT CONDITIONED-REINFORCEMENT AND CONDITIONED-REWARD.ADDICTION BIOLOGY. VOL. 16. ISSUE 3. P. 416-427 36 77% 13
5 MACCIONI, P , ZARU, A , LOI, B , LOBINA, C , CARAI, MAM , GESSA, GL , CAPRA, A , MUGNAINI, C , PASQUINI, S , CORELLI, F , ET AL (2012) COMPARISON OF THE EFFECT OF THE GABAB RECEPTOR AGONIST, BACLOFEN, AND THE POSITIVE ALLOSTERIC MODULATOR OF THE GABAB RECEPTOR, GS39783, ON ALCOHOL SELF-ADMINISTRATION IN 3 DIFFERENT LINES OF ALCOHOL-PREFERRING RATS.ALCOHOLISM-CLINICAL AND EXPERIMENTAL RESEARCH. VOL. 36. ISSUE 10. P. 1748-1766 47 55% 11
6 FATTORE, L , SPANO, MS , COSSU, G , SCHERMA, M , FRATTA, W , FADDA, P , (2009) BACLOFEN PREVENTS DRUG-INDUCED REINSTATEMENT OF EXTINGUISHED NICOTINE-SEEKING BEHAVIOUR AND NICOTINE PLACE PREFERENCE IN RODENTS.EUROPEAN NEUROPSYCHOPHARMACOLOGY. VOL. 19. ISSUE 7. P. 487-498 48 52% 30
7 MACCIONI, P , FANTINI, N , FROESTL, W , CARAI, MAM , GESSA, GL , COLOMBO, G , (2008) SPECIFIC REDUCTION OF ALCOHOL'S MOTIVATIONAL PROPERTIES BY THE POSITIVE ALLOSTERIC MODULATOR OF THE GABA(B) RECEPTOR, GS39783 - COMPARISON WITH THE EFFECT OF THE GABA(B) RECEPTOR DIRECT AGONIST, BACLOFEN.ALCOHOLISM-CLINICAL AND EXPERIMENTAL RESEARCH. VOL. 32. ISSUE 9. P. 1558 -1564 33 73% 23
8 FILIP, M , FRANKOWSKA, M , (2008) GABA(B) RECEPTORS IN DRUG ADDICTION.PHARMACOLOGICAL REPORTS. VOL. 60. ISSUE 6. P. 755 -770 61 39% 29
9 PHILLIPS, TJ , REED, C , (2014) TARGETING GABA(B) RECEPTORS FOR ANTI-ABUSE DRUG DISCOVERY.EXPERT OPINION ON DRUG DISCOVERY. VOL. 9. ISSUE 11. P. 1307 -1317 43 47% 7
10 ROLLAND, B , AUFFRET, M , FRANCHITTO, N , (2016) SAFETY REPORTS ON THE OFF-LABEL USE OF BACLOFEN FOR ALCOHOL-DEPENDENCE: RECOMMENDATIONS TO IMPROVE CAUSALITY ASSESSMENT.EXPERT OPINION ON DRUG SAFETY. VOL. 15. ISSUE 6. P. 747 -751 24 75% 1

Classes with closest relation at Level 1


Rank Class id link
1 5603 GABAB RECEPTOR//BACLOFEN//GABAB
2 7322 ACAMPROSATE//NALTREXONE//NALMEFENE
3 22769 CONDITIONED PLACE PREFERENCE//DIETHYLPROPION//DOPAMINE RECEPTOR SUPERSENSITIVITY
4 9247 INTRATHECAL BACLOFEN//SPASTICITY//BACLOFEN
5 10149 REINSTATEMENT//BEHAV NEUROSCI BRANCH//SELF ADMINISTRATION
6 10720 VENTRAL TEGMENTAL AREA//NEURONAL NETWORKS SECT//SUBSTANTIA NIGRA
7 15080 VIGABATRIN//GAMMA VINYL GABA//VISUAL FIELD CONSTRICTION
8 1021 BEHAVIORAL SENSITIZATION//COCAINE//SENSITIZATION
9 2140 ALCOHOL//ALCOHOL PREFERRING RATS//ALCOHOL PREFERENCE
10 6765 KAPPA OPIOID RECEPTOR//BIOL ADDICT DIS//DYNORPHIN

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