Class information for:
Level 1: BEPRIDIL//CAS 117241 46 0//REVUE DE MEDECINE

Basic class information
Class id #P Avg. number of
references		 Database coverage
of references
22882 365 25.9 58%


Bar chart of Publication_year

Last years might be incomplete

Hierarchy of classes
The table includes all classes above and classes immediately below the current class.


Cluster id Level Cluster label #P
8 4 CARDIAC & CARDIOVASCULAR SYSTEM//PERIPHERAL VASCULAR DISEASES//CARDIOL 1276458
11 3       ATRIAL FIBRILLATION//CARDIAC & CARDIOVASCULAR SYSTEM//CATHETER ABLATION 130936
822 2             CALCIUM ANTAGONISTS//CALCIUM CHANNEL BLOCKERS//NIFEDIPINE 11902
22882 1                   BEPRIDIL//CAS 117241 46 0//REVUE DE MEDECINE 365

Terms with highest relevance score


rank Term termType Chi square Shr. of publ. in
class containing
term		 Class's shr. of
term's tot. occurrences		 #P with
term in
class
1 BEPRIDIL authKW 2014705 14% 47% 51
2 CAS 117241 46 0 authKW 250973 1% 100% 3
3 REVUE DE MEDECINE journal 167867 5% 12% 17
4 3 4 ALLYL 1 PIPERAZINYL 2 2 DIMETHYLPROPYL METHYL 1 4 DIHYDRO 2 6 DIMETHYL 4 3 NITROPHENYL 3 5 PYRIDINEDICARB authKW 167316 1% 100% 2
5 MUSCARINIC ACETYLCHOLINE RECEPTOR OPERATED POTASSIUM CURRENT authKW 167316 1% 100% 2
6 NKY 722 PHARMACOLOGY authKW 167316 1% 100% 2
7 NKY 722 authKW 150582 1% 60% 3
8 3 4 ALLYL 1 PIPERAZINYL 2 2 DIMETHYLPROPYLMETHYL 1 4 DIHYDRO 2 6 DIMETHYL 4 3 NITROPHENYL 3 5 PYRIDINEDICARBO authKW 83658 0% 100% 1
9 ANTI ELECTRICAL REMODELLING authKW 83658 0% 100% 1
10 ANTIARRHYTHMIC DRUGS INVIVO authKW 83658 0% 100% 1

Web of Science journal categories


Rank Term Chi square Shr. of publ. in
class containing
term		 Class's shr. of
term's tot. occurrences		 #P with
term in
class
1 Cardiac & Cardiovascular System 4142 42% 0% 153
2 Pharmacology & Pharmacy 2989 53% 0% 192
3 Peripheral Vascular Diseases 191 7% 0% 27
4 Chemistry, Medicinal 55 4% 0% 16
5 Medicine, General & Internal 46 7% 0% 25
6 Toxicology 11 2% 0% 9
7 Chemistry, Multidisciplinary 2 5% 0% 18
8 Physiology 1 2% 0% 6
9 Medicine, Research & Experimental 0 2% 0% 6
10 Engineering, Biomedical 0 1% 0% 3

Address terms


Rank Term Chi square Shr. of publ. in
class containing
term		 Class's shr. of
term's tot. occurrences		 #P with
term in
class
1 BIOPHYS 27 BD J MOULIN 83658 0% 100% 1
2 INTELLIGENT CLIN INNOVAT 83658 0% 100% 1
3 NIHON UNIV MEDCHIYODA KU 83658 0% 100% 1
4 PRECLIN DEV 1 83658 0% 100% 1
5 CARDIOLBUNKYO KU 27885 0% 33% 1
6 PHARMACOL CHINESE MATERIA MED 13941 0% 17% 1
7 REGENERAT MED THER EUT GENET MED RE 13941 0% 17% 1
8 CARDIOANGIOL 11632 1% 3% 4
9 SURG ANESTHESIOL CRIT CARE MED 9294 0% 11% 1
10 MED DENS PHARMACEUT SCI 7603 0% 9% 1

Journals


Rank Term Chi square Shr. of publ. in
class containing
term		 Class's shr. of
term's tot. occurrences		 #P with
term in
class
1 REVUE DE MEDECINE 167867 5% 12% 17
2 AMERICAN JOURNAL OF CARDIOLOGY 6084 12% 0% 44
3 ARCHIVES INTERNATIONALES DE PHARMACODYNAMIE ET DE THERAPIE 5321 3% 1% 12
4 JOURNAL OF CARDIOVASCULAR PHARMACOLOGY 5125 7% 0% 26
5 CIRCULATION JOURNAL 4641 4% 0% 16
6 ANNALES DE CARDIOLOGIE ET D ANGEIOLOGIE 3669 2% 1% 8
7 EUROPEAN JOURNAL OF PHARMACOLOGY 2147 7% 0% 27
8 THERAPIE 2096 2% 0% 8
9 LYON MEDICAL 1222 1% 1% 2
10 ARCHIVES DES MALADIES DU COEUR ET DES VAISSEAUX 1060 2% 0% 9

Author Key Words


Rank Term Chi square Shr. of publ. in
class containing
term		 Class's shr. of
term's tot. occurrences		 #P with
term in
class		 LCSH search Wikipedia search
1 BEPRIDIL 2014705 14% 47% 51 Search BEPRIDIL Search BEPRIDIL
2 CAS 117241 46 0 250973 1% 100% 3 Search CAS+117241+46+0 Search CAS+117241+46+0
3 3 4 ALLYL 1 PIPERAZINYL 2 2 DIMETHYLPROPYL METHYL 1 4 DIHYDRO 2 6 DIMETHYL 4 3 NITROPHENYL 3 5 PYRIDINEDICARB 167316 1% 100% 2 Search 3+4+ALLYL+1+PIPERAZINYL+2+2+DIMETHYLPROPYL+METHYL+1+4+DIHYDRO+2+6+DIMETHYL+4+3+NITROPHENYL+3+5+PYRIDINEDICARB Search 3+4+ALLYL+1+PIPERAZINYL+2+2+DIMETHYLPROPYL+METHYL+1+4+DIHYDRO+2+6+DIMETHYL+4+3+NITROPHENYL+3+5+PYRIDINEDICARB
4 MUSCARINIC ACETYLCHOLINE RECEPTOR OPERATED POTASSIUM CURRENT 167316 1% 100% 2 Search MUSCARINIC+ACETYLCHOLINE+RECEPTOR+OPERATED+POTASSIUM+CURRENT Search MUSCARINIC+ACETYLCHOLINE+RECEPTOR+OPERATED+POTASSIUM+CURRENT
5 NKY 722 PHARMACOLOGY 167316 1% 100% 2 Search NKY+722+PHARMACOLOGY Search NKY+722+PHARMACOLOGY
6 NKY 722 150582 1% 60% 3 Search NKY+722 Search NKY+722
7 3 4 ALLYL 1 PIPERAZINYL 2 2 DIMETHYLPROPYLMETHYL 1 4 DIHYDRO 2 6 DIMETHYL 4 3 NITROPHENYL 3 5 PYRIDINEDICARBO 83658 0% 100% 1 Search 3+4+ALLYL+1+PIPERAZINYL+2+2+DIMETHYLPROPYLMETHYL+1+4+DIHYDRO+2+6+DIMETHYL+4+3+NITROPHENYL+3+5+PYRIDINEDICARBO Search 3+4+ALLYL+1+PIPERAZINYL+2+2+DIMETHYLPROPYLMETHYL+1+4+DIHYDRO+2+6+DIMETHYL+4+3+NITROPHENYL+3+5+PYRIDINEDICARBO
8 ANTI ELECTRICAL REMODELLING 83658 0% 100% 1 Search ANTI+ELECTRICAL+REMODELLING Search ANTI+ELECTRICAL+REMODELLING
9 ANTIARRHYTHMIC DRUGS INVIVO 83658 0% 100% 1 Search ANTIARRHYTHMIC+DRUGS+INVIVO Search ANTIARRHYTHMIC+DRUGS+INVIVO
10 ARTERIAL INJURY PROTECTION 83658 0% 100% 1 Search ARTERIAL+INJURY+PROTECTION Search ARTERIAL+INJURY+PROTECTION

Core articles
The table includes core articles in the class. The following variables is taken into account for the relevance score of an article in a cluster c:
(1) Number of references referring to publications in the class.
(2) Share of total number of active references referring to publications in the class.
(3) Age of the article. New articles get higher score than old articles.
(4) Citation rate, normalized to year.


Rank Reference # ref.
in cl.		 Shr. of ref. in
cl.		 Citations
1 HOLLINGSHEAD, LM , FAULDS, D , FITTON, A , (1992) BEPRIDIL - A REVIEW OF ITS PHARMACOLOGICAL PROPERTIES AND THERAPEUTIC USE IN STABLE ANGINA-PECTORIS.DRUGS. VOL. 44. ISSUE 5. P. 835-857 89 85% 35
2 GILL, A , FLAIM, SF , DAMIANO, BP , SIT, SP , BRANNAN, MD , (1992) PHARMACOLOGY OF BEPRIDIL.AMERICAN JOURNAL OF CARDIOLOGY. VOL. 69. ISSUE 11. P. D11-D16 28 90% 38
3 ISHIZAKA, T , TAKAHARA, A , IWASAKI, H , MITSUMORI, Y , KISE, H , NAKAMURA, Y , SUGIYAMA, A , (2008) COMPARISON OF ELECTROPHARMACOLOGICAL EFFECTS OF BEPRIDIL AND SOTALOL IN HALOTHANE-ANESTHETIZED DOGS.CIRCULATION JOURNAL. VOL. 72. ISSUE 6. P. 1003 -1011 23 52% 6
4 SINGH, BN , (1992) SAFETY PROFILE OF BEPRIDIL DETERMINED FROM CLINICAL-TRIALS IN CHRONIC STABLE ANGINA IN THE UNITED-STATES.AMERICAN JOURNAL OF CARDIOLOGY. VOL. 69. ISSUE 11. P. D68-D74 21 95% 20
5 KANG, L , ZHENG, MQ , MORISHIMA, M , WANG, Y , KAKU, T , ONO, K , (2009) BEPRIDIL UP-REGULATES CARDIAC NA+ CHANNELS AS A LONG-TERM EFFECT BY BLUNTING PROTEASOME SIGNALS THROUGH INHIBITION OF CALMODULIN ACTIVITY.BRITISH JOURNAL OF PHARMACOLOGY. VOL. 157. ISSUE 3. P. 404 -414 21 53% 15
6 AOYAMA, Y , NIWANO, S , NIWANO, H , SATOH, A , KISHIHARA, J , ISHIKAWA, S , MURAKAMI, M , FUKUMOTO, K , UENO, K , IZUMI, T , (2011) REPETITIVE EVALUATION OF FIBRILLATION CYCLE LENGTH PREDICTS THE EFFICACY OF BEPRIDIL FOR INTERRUPTION OF LONG-LASTING PERSISTENT ATRIAL FIBRILLATION.INTERNATIONAL HEART JOURNAL. VOL. 52. ISSUE 6. P. 353-358 16 67% 3
7 ZELLER, FP , SPINLER, SA , (1987) BEPRIDIL - A NEW LONG-ACTING CALCIUM-CHANNEL BLOCKING-AGENT.DRUG INTELLIGENCE & CLINICAL PHARMACY. VOL. 21. ISSUE 6. P. 487-492 27 90% 4
8 SUZUKI, S , KURATA, Y , LI, PL , NOTSU, T , HASEGAWA, A , IKEDA, N , KATO, M , MIAKE, J , SAKATA, S , SHIOTA, G , ET AL (2012) STABILIZATION OF KV1.5 CHANNEL PROTEIN BY BEPRIDIL THROUGH ITS ACTION AS A CHEMICAL CHAPERONE.EUROPEAN JOURNAL OF PHARMACOLOGY. VOL. 696. ISSUE 1-3. P. 28 -34 18 55% 2
9 SHIGA, T , HASHIGUCHI, M , NAGANUMA, M , SUZUKI, A , HAGIWARA, N , (2013) CONTRIBUTING FACTORS TO THE APPARENT CLEARANCE OF BEPRIDIL IN PATIENTS WITH PAROXYSMAL OR PERSISTENT ATRIAL FIBRILLATION: ANALYSIS USING POPULATION PHARMACOKINETICS.THERAPEUTIC DRUG MONITORING. VOL. 35. ISSUE 3. P. 367 -373 13 72% 0
10 FLAIM, SF , CUMMINGS, DM , (1986) BEPRIDIL HYDROCHLORIDE - A REVIEW OF ITS PHARMACOLOGICAL PROPERTIES.CURRENT THERAPEUTIC RESEARCH-CLINICAL AND EXPERIMENTAL. VOL. 39. ISSUE 4. P. 568-597 34 71% 7

Classes with closest relation at Level 1


Rank Class id link
1 4227 NISOLDIPINE//GALLOPAMIL//ELGODIPINE
2 36861 FISIOL CELLUARE//INDENOLOL//K COMPETITION
3 26073 ZATEBRADINE//ALINIDINE//YM758
4 35384 CD 832//PRANIDIPINE//KT 362
5 15182 ANIPAMIL//KINGS CARDIOVASC BIOL MED//ISCHEMIA AND RE PERFUSION
6 31516 SALVICINE//DIPFLUZINE//DIPFLUZINE HYDROCHLORIDE
7 4492 DIHYDROPYRIDINE//SR 33557//BAY K 8644
8 30417 3 CHLORO 1 5H DIBENZB FAZEPINE 5 YL PROPAN 1 ONE//DIBROMIDE RADICAL ANION//DITHIOCYANATE RADICAL ANION
9 33416 SODIUM ACTIVATED POTASSIUM CHANNELS//NA ACTIVATED K CHANNELS//CHANNEL PROTEIN INTERACTIONS
10 21841 DILTIAZEM//DESACETYLDILTIAZEM//DEACETYLDILTIAZEM

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