Class information for:
Level 1: RETT SYNDROME//MECP2//CDKL5

Basic class information
Class id #P Avg. number of
references		 Database coverage
of references
2548 2211 40.0 83%


Bar chart of Publication_year

Last years might be incomplete

Hierarchy of classes
The table includes all classes above and classes immediately below the current class.


Cluster id Level Cluster label #P
0 4 BIOCHEMISTRY & MOLECULAR BIOLOGY//CELL BIOLOGY//ONCOLOGY 4064930
196 3       GENETICS & HEREDITY//FRAGILE X SYNDROME//AMERICAN JOURNAL OF MEDICAL GENETICS 53756
1566 2             FRAGILE X SYNDROME//RETT SYNDROME//FRAGILE X 7353
2548 1                   RETT SYNDROME//MECP2//CDKL5 2211

Terms with highest relevance score


rank Term termType Chi square Shr. of publ. in
class containing
term		 Class's shr. of
term's tot. occurrences		 #P with
term in
class
1 RETT SYNDROME authKW 9399828 38% 82% 830
2 MECP2 authKW 3323133 16% 69% 350
3 CDKL5 authKW 639138 2% 86% 54
4 MECP2 GENE authKW 538546 2% 100% 39
5 MECP2 MUTATION authKW 372839 1% 100% 27
6 METHYL CPG BINDING PROTEIN 2 authKW 362172 2% 66% 40
7 WESTERN SYDNEY GENET PROGRAM address 340342 3% 39% 63
8 BRAIN & DEVELOPMENT journal 210339 11% 6% 235
9 RETT address 194185 1% 94% 15
10 PRESERVED SPEECH VARIANT authKW 179515 1% 100% 13

Web of Science journal categories


Rank Term Chi square Shr. of publ. in
class containing
term		 Class's shr. of
term's tot. occurrences		 #P with
term in
class
1 Clinical Neurology 11891 32% 0% 717
2 Genetics & Heredity 6936 24% 0% 531
3 Pediatrics 5866 18% 0% 406
4 Neurosciences 2452 21% 0% 468
5 Education, Special 1106 2% 0% 52
6 Rehabilitation 918 5% 0% 102
7 Psychology, Developmental 633 3% 0% 72
8 Biochemistry & Molecular Biology 322 14% 0% 320
9 Psychiatry 306 5% 0% 118
10 Cell Biology 112 6% 0% 128

Address terms


Rank Term Chi square Shr. of publ. in
class containing
term		 Class's shr. of
term's tot. occurrences		 #P with
term in
class
1 WESTERN SYDNEY GENET PROGRAM 340342 3% 39% 63
2 RETT SYNDROME 196389 1% 89% 16
3 RETT 194185 1% 94% 15
4 GENET EPIGENET CONTROL GENE EXP S 139238 0% 92% 11
5 TUSCANY RETT 96662 0% 100% 7
6 CIVITAN INT 87778 2% 17% 38
7 BLUE BIRD CIRCLE RETT 82853 0% 100% 6
8 P PATHOPHYSIOL REHABIL UNIT 75178 0% 78% 7
9 SAN RAFFAELE RETT 75178 0% 78% 7
10 SAN RAFFAELE RETT UNIT 75178 0% 78% 7

Journals


Rank Term Chi square Shr. of publ. in
class containing
term		 Class's shr. of
term's tot. occurrences		 #P with
term in
class
1 BRAIN & DEVELOPMENT 210339 11% 6% 235
2 JOURNAL OF CHILD NEUROLOGY 30720 5% 2% 104
3 NEUROPEDIATRICS 13109 2% 2% 44
4 PEDIATRIC NEUROLOGY 8088 2% 1% 50
5 EUROPEAN CHILD & ADOLESCENT PSYCHIATRY 7139 1% 2% 28
6 AMERICAN JOURNAL OF MEDICAL GENETICS 6989 3% 1% 67
7 EUROPEAN JOURNAL OF HUMAN GENETICS 6609 2% 1% 42
8 JOURNAL OF NEURODEVELOPMENTAL DISORDERS 6356 0% 4% 11
9 AMERICAN JOURNAL OF MEDICAL GENETICS PART A 5443 2% 1% 48
10 HUMAN MOLECULAR GENETICS 5180 3% 1% 61

Author Key Words


Rank Term Chi square Shr. of publ. in
class containing
term		 Class's shr. of
term's tot. occurrences		 #P with
term in
class		 LCSH search Wikipedia search
1 RETT SYNDROME 9399828 38% 82% 830 Search RETT+SYNDROME Search RETT+SYNDROME
2 MECP2 3323133 16% 69% 350 Search MECP2 Search MECP2
3 CDKL5 639138 2% 86% 54 Search CDKL5 Search CDKL5
4 MECP2 GENE 538546 2% 100% 39 Search MECP2+GENE Search MECP2+GENE
5 MECP2 MUTATION 372839 1% 100% 27 Search MECP2+MUTATION Search MECP2+MUTATION
6 METHYL CPG BINDING PROTEIN 2 362172 2% 66% 40 Search METHYL+CPG+BINDING+PROTEIN+2 Search METHYL+CPG+BINDING+PROTEIN+2
7 RETT 184618 1% 70% 19 Search RETT Search RETT
8 PRESERVED SPEECH VARIANT 179515 1% 100% 13 Search PRESERVED+SPEECH+VARIANT Search PRESERVED+SPEECH+VARIANT
9 FOXG1 176901 1% 41% 31 Search FOXG1 Search FOXG1
10 METHYL CPG BINDING PROTEIN 2 MECP2 150357 1% 78% 14 Search METHYL+CPG+BINDING+PROTEIN+2+MECP2 Search METHYL+CPG+BINDING+PROTEIN+2+MECP2

Core articles
The table includes core articles in the class. The following variables is taken into account for the relevance score of an article in a cluster c:
(1) Number of references referring to publications in the class.
(2) Share of total number of active references referring to publications in the class.
(3) Age of the article. New articles get higher score than old articles.
(4) Citation rate, normalized to year.


Rank Reference # ref. in
cl.		 Shr. of ref. in
cl.		 Citations
1 LIYANAGE, VRB , RASTEGAR, M , (2014) RETT SYNDROME AND MECP2.NEUROMOLECULAR MEDICINE. VOL. 16. ISSUE 2. P. 231-264 216 80% 14
2 LEONARD, H , COBB, S , DOWNS, J , (2017) CLINICAL AND BIOLOGICAL PROGRESS OVER 50 YEARS IN RETT SYNDROME.NATURE REVIEWS NEUROLOGY. VOL. 13. ISSUE 1. P. 37 -51 193 95% 0
3 CHAHROUR, M , ZOGHBI, HY , (2007) THE STORY OF RETT SYNDROME: FROM CLINIC TO NEUROBIOLOGY.NEURON. VOL. 56. ISSUE 3. P. 422-437 112 93% 531
4 LOMBARDI, LM , BAKER, SA , ZOGHBI, HY , (2015) MECP2 DISORDERS: FROM THE CLINIC TO MICE AND BACK.JOURNAL OF CLINICAL INVESTIGATION. VOL. 125. ISSUE 8. P. 2914 -2923 114 84% 24
5 LYST, MJ , BIRD, A , (2015) RETT SYNDROME: A COMPLEX DISORDER WITH SIMPLE ROOTS.NATURE REVIEWS GENETICS. VOL. 16. ISSUE 5. P. 261 -274 109 78% 29
6 GUY, J , CHEVAL, H , SELFRIDGE, J , BIRD, A , (2011) THE ROLE OF MECP2 IN THE BRAIN.ANNUAL REVIEW OF CELL AND DEVELOPMENTAL BIOLOGY, VOL 27. VOL. 27. ISSUE . P. 631-652 104 82% 176
7 KATZ, DM , BERGER-SWEENEY, JE , EUBANKS, JH , JUSTICE, MJ , NEUL, JL , POZZO-MILLER, L , BLUE, ME , CHRISTIAN, D , CRAWLEY, JN , GIUSTETTO, M , ET AL (2012) PRECLINICAL RESEARCH IN RETT SYNDROME: SETTING THE FOUNDATION FOR TRANSLATIONAL SUCCESS.DISEASE MODELS & MECHANISMS. VOL. 5. ISSUE 6. P. 733-745 112 85% 43
8 CALFA, G , PERCY, AK , POZZO-MILLER, L , (2011) EXPERIMENTAL MODELS OF RETT SYNDROME BASED ON MECP2 DYSFUNCTION.EXPERIMENTAL BIOLOGY AND MEDICINE. VOL. 236. ISSUE 1. P. 3 -19 121 74% 49
9 KATZ, DM , BIRD, A , COENRAADS, M , GRAY, SJ , MENON, DU , PHILPOT, BD , TARQUINIO, DC , (2016) RETT SYNDROME: CROSSING THE THRESHOLD TO CLINICAL TRANSLATION.TRENDS IN NEUROSCIENCES. VOL. 39. ISSUE 2. P. 100 -113 80 74% 8
10 DELLA SALA, G , PIZZORUSSO, T , (2014) SYNAPTIC PLASTICITY AND SIGNALING IN RETT SYNDROME.DEVELOPMENTAL NEUROBIOLOGY. VOL. 74. ISSUE 2. P. 178-196 115 71% 12

Classes with closest relation at Level 1


Rank Class id link
1 17131 MTA1//CHD5//METASTASIS ASSOCIATED GENE 1
2 8667 X LINKED MENTAL RETARDATION//XLMR//PQBP1
3 6500 EPIGENETICS//DNA METHYLATION//HISTONE ACETYLATION
4 5364 AUTISM//BROAD AUTISM PHENOTYPE//MOLECULAR AUTISM
5 34368 BRITISH PAEDIAT SURVEILLANCE UNIT//COPPER SULFATE POISONING//BLUISH VOMITING
6 15664 NEUROLIGIN//NEUREXIN//NRXN1
7 2365 PRADER WILLI SYNDROME//ANGELMAN SYNDROME//UBE3A
8 7812 AUTISM//SHAIK AL AMODI AUTISM CHAIR//NIEHS CHILDRENS ENVIRONM HLTH
9 22078 ICF SYNDROME//EXCELLENCE MOL GENET CANC HUMAN DIS//COBRALINE 1
10 6924 SUBTELOMERIC REARRANGEMENTS//ARRAY CGH//MBD5

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