Class information for:
Level 1: MENKES DISEASE//ATP7A//COPPER TRANSPORT

Basic class information
Class id #P Avg. number of
references		 Database coverage
of references
2857 2129 44.9 81%


Bar chart of Publication_year

Last years might be incomplete

Hierarchy of classes
The table includes all classes above and classes immediately below the current class.


Cluster id Level Cluster label #P
4 4 ENVIRONMENTAL SCIENCES//GEOSCIENCES, MULTIDISCIPLINARY//METEOROLOGY & ATMOSPHERIC SCIENCES 1766162
184 3       METALLOTHIONEIN//WILSONS DISEASE//CADMIUM 56156
1113 2             WILSONS DISEASE//METALLOTHIONEIN//ATP7B 9713
2857 1                   MENKES DISEASE//ATP7A//COPPER TRANSPORT 2129

Terms with highest relevance score


rank Term termType Chi square Shr. of publ. in
class containing
term		 Class's shr. of
term's tot. occurrences		 #P with
term in
class
1 MENKES DISEASE authKW 2029883 8% 82% 172
2 ATP7A authKW 1179725 5% 81% 101
3 COPPER TRANSPORT authKW 671994 4% 56% 83
4 ATP7B authKW 504086 4% 38% 93
5 COPPER HOMEOSTASIS authKW 455527 3% 51% 62
6 CTR1 authKW 309024 2% 53% 41
7 COPPER CHAPERONE authKW 278850 2% 59% 33
8 METALLOCHAPERONE authKW 271740 2% 56% 34
9 COPPER TRANSPORTER authKW 261450 1% 65% 28
10 OCCIPITAL HORN SYNDROME authKW 260738 1% 91% 20

Web of Science journal categories


Rank Term Chi square Shr. of publ. in
class containing
term		 Class's shr. of
term's tot. occurrences		 #P with
term in
class
1 Biochemistry & Molecular Biology 6591 47% 0% 997
2 Genetics & Heredity 1014 10% 0% 220
3 Biophysics 705 8% 0% 162
4 Cell Biology 392 9% 0% 190
5 Microbiology 348 7% 0% 144
6 Chemistry, Inorganic & Nuclear 246 5% 0% 104
7 Pediatrics 167 4% 0% 87
8 Nutrition & Dietetics 110 3% 0% 54
9 Endocrinology & Metabolism 108 4% 0% 86
10 Medicine, Research & Experimental 87 4% 0% 77

Address terms


Rank Term Chi square Shr. of publ. in
class containing
term		 Class's shr. of
term's tot. occurrences		 #P with
term in
class
1 UNIT HUMAN COPPER METAB 151470 1% 81% 13
2 UNIT PEDIAT GENET 115399 1% 62% 13
3 SECT TRANSLAT NEUROSCI 83433 0% 73% 8
4 MED 0058 32259 0% 38% 6
5 BIOL MOL CELULAR ROSARIO MICROBIOL 28682 0% 100% 2
6 CARDIOVASC LUNG VASC BIOL 28682 0% 100% 2
7 CEADRDCBMC 28682 0% 100% 2
8 MURDOCH BIRTH DEFECTS 26016 0% 26% 7
9 BIOINFORMAT EXP GENICA 25086 0% 25% 7
10 HLTH DIETET 23458 0% 27% 6

Journals


Rank Term Chi square Shr. of publ. in
class containing
term		 Class's shr. of
term's tot. occurrences		 #P with
term in
class
1 METALLOMICS 45527 3% 6% 57
2 BIOMETALS 19006 2% 3% 48
3 JOURNAL OF BIOLOGICAL INORGANIC CHEMISTRY 7709 2% 2% 33
4 JOURNAL OF TRACE ELEMENTS IN EXPERIMENTAL MEDICINE 3182 0% 3% 8
5 JOURNAL OF BIOLOGICAL CHEMISTRY 2976 9% 0% 184
6 JOURNAL OF INHERITED METABOLIC DISEASE 2801 1% 1% 30
7 JOURNAL OF INORGANIC BIOCHEMISTRY 2245 1% 1% 30
8 BRAIN & DEVELOPMENT 2236 1% 1% 24
9 JOURNAL OF TRACE ELEMENTS IN MEDICINE AND BIOLOGY 2102 1% 1% 13
10 BIOCHEMISTRY 1172 3% 0% 69

Author Key Words


Rank Term Chi square Shr. of publ. in
class containing
term		 Class's shr. of
term's tot. occurrences		 #P with
term in
class		 LCSH search Wikipedia search
1 MENKES DISEASE 2029883 8% 82% 172 Search MENKES+DISEASE Search MENKES+DISEASE
2 ATP7A 1179725 5% 81% 101 Search ATP7A Search ATP7A
3 COPPER TRANSPORT 671994 4% 56% 83 Search COPPER+TRANSPORT Search COPPER+TRANSPORT
4 ATP7B 504086 4% 38% 93 Search ATP7B Search ATP7B
5 COPPER HOMEOSTASIS 455527 3% 51% 62 Search COPPER+HOMEOSTASIS Search COPPER+HOMEOSTASIS
6 CTR1 309024 2% 53% 41 Search CTR1 Search CTR1
7 COPPER CHAPERONE 278850 2% 59% 33 Search COPPER+CHAPERONE Search COPPER+CHAPERONE
8 METALLOCHAPERONE 271740 2% 56% 34 Search METALLOCHAPERONE Search METALLOCHAPERONE
9 COPPER TRANSPORTER 261450 1% 65% 28 Search COPPER+TRANSPORTER Search COPPER+TRANSPORTER
10 OCCIPITAL HORN SYNDROME 260738 1% 91% 20 Search OCCIPITAL+HORN+SYNDROME Search OCCIPITAL+HORN+SYNDROME

Core articles
The table includes core articles in the class. The following variables is taken into account for the relevance score of an article in a cluster c:
(1) Number of references referring to publications in the class.
(2) Share of total number of active references referring to publications in the class.
(3) Age of the article. New articles get higher score than old articles.
(4) Citation rate, normalized to year.


Rank Reference # ref. in
cl.		 Shr. of ref. in
cl.		 Citations
1 LUTSENKO, S , BARNES, NL , BARTEE, MY , DMITRIEV, OY , (2007) FUNCTION AND REGULATION OF HUMAN COPPER-TRANSPORTING ATPASES.PHYSIOLOGICAL REVIEWS. VOL. 87. ISSUE 3. P. 1011-1046 194 67% 275
2 BOAL, AK , ROSENZWEIG, AC , (2009) STRUCTURAL BIOLOGY OF COPPER TRAFFICKING.CHEMICAL REVIEWS. VOL. 109. ISSUE 10. P. 4760 -4779 136 79% 152
3 TUMER, Z , (2013) AN OVERVIEW AND UPDATE OF ATP7A MUTATIONS LEADING TO MENKES DISEASE AND OCCIPITAL HORN SYNDROME.HUMAN MUTATION. VOL. 34. ISSUE 3. P. 417-429 114 97% 18
4 DE BIE, P , MULLER, P , WIJMENGA, C , KLOMP, LWJ , (2007) MOLECULAR PATHOGENESIS OF WILSON AND MENKES DISEASE: CORRELATION OF MUTATIONS WITH MOLECULAR DEFECTS AND DISEASE PHENOTYPES.JOURNAL OF MEDICAL GENETICS. VOL. 44. ISSUE 11. P. 673 -688 146 64% 132
5 TELIANIDIS, J , HUNG, YH , MATERIA, S , LA FONTAINE, S , (2013) ROLE OF THE P-TYPE ATPASES, ATP7A AND ATP7B IN BRAIN COPPER HOMEOSTASIS.FRONTIERS IN AGING NEUROSCIENCE. VOL. 5. ISSUE . P. - 131 67% 23
6 LA FONTAINE, S , MERCER, JFB , (2007) TRAFFICKING OF THE COPPER-ATPASES, ATP7A AND ATP7B: ROLE IN COPPER HOMEOSTASIS.ARCHIVES OF BIOCHEMISTRY AND BIOPHYSICS. VOL. 463. ISSUE 2. P. 149-167 124 72% 152
7 KALER, SG , (2011) ATP7A-RELATED COPPER TRANSPORT DISEASES-EMERGING CONCEPTS AND FUTURE TRENDS.NATURE REVIEWS NEUROLOGY. VOL. 7. ISSUE 1. P. 15 -29 96 71% 130
8 LENARTOWICZ, M , KRZEPTOWSKI, W , LIPINSKI, P , GRZMIL, P , STARZYNSKI, R , PIERZCHALA, O , MOLLER, LB , (2015) MOTTLED MICE AND NON-MAMMALIAN MODELS OF MENKES DISEASE.FRONTIERS IN MOLECULAR NEUROSCIENCE. VOL. 8. ISSUE . P. - 111 76% 1
9 VAN DEN BERGHE, PVE , KLOMP, L , (2010) POSTTRANSLATIONAL REGULATION OF COPPER TRANSPORTERS.JOURNAL OF BIOLOGICAL INORGANIC CHEMISTRY. VOL. 15. ISSUE 1. P. 37 -46 104 85% 26
10 ROSENZWEIG, AC , ARGUELLO, JM , (2012) TOWARD A MOLECULAR UNDERSTANDING OF METAL TRANSPORT BY P-1B-TYPE ATPASES.METAL TRANSPORTERS. VOL. 69. ISSUE . P. 113-136 93 87% 13

Classes with closest relation at Level 1


Rank Class id link
1 4943 WILSONS DISEASE//ATP7B//HEPATOLENTICULAR DEGENERATION
2 18017 LEC RAT//LONG EVANS CINNAMON RAT//INDIAN CHILDHOOD CIRRHOSIS
3 15827 AFT1//FET3//SIDEROPHORE
4 13191 HEAVY METAL RESISTANCE//CUPRIAVIDUS METALLIDURANS CH34//METAL RESISTANCE
5 25841 TETRATHIOMOLYBDATE//CLIOQUINOL//UNITA RIC CATANIA
6 21819 BEDLINGTON TERRIER//MURR1//COMMD1
7 7449 COPPER DEFICIENCY//COPPER DEFICIENT//COPPER STATUS
8 12765 CERULOPLASMIN//ACERULOPLASMINEMIA//FERROXIDASE
9 7584 FERRIC UPTAKE REGULATOR//FUR//NIKR
10 8955 MITOCHONDRIAL TRANSLATION//MITOCHONDRIAL RIBOSOMAL PROTEIN//SCO PROTEIN

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