Class information for:
Level 1: INNER BLOOD RETINAL BARRIER//PROTON COUPLED ORGANIC CATION ANTIPORTER//RETINAL CAPILLARY ENDOTHELIAL CELLS

Basic class information
Class id #P Avg. number of
references		 Database coverage
of references
30937 161 32.4 70%


Bar chart of Publication_year

Last years might be incomplete

Hierarchy of classes
The table includes all classes above and classes immediately below the current class.


Cluster id Level Cluster label #P
0 4 BIOCHEMISTRY & MOLECULAR BIOLOGY//CELL BIOLOGY//ONCOLOGY 4064930
230 3       P GLYCOPROTEIN//FMO3//TRIMETHYLAMINURIA 49374
1155 2             PEPT1//ORGANIC CATION TRANSPORTER//OATP1B1 9490
30937 1                   INNER BLOOD RETINAL BARRIER//PROTON COUPLED ORGANIC CATION ANTIPORTER//RETINAL CAPILLARY ENDOTHELIAL CELLS 161

Terms with highest relevance score


rank Term termType Chi square Shr. of publ. in
class containing
term		 Class's shr. of
term's tot. occurrences		 #P with
term in
class
1 INNER BLOOD RETINAL BARRIER authKW 2445267 12% 68% 19
2 PROTON COUPLED ORGANIC CATION ANTIPORTER authKW 758646 2% 100% 4
3 RETINAL CAPILLARY ENDOTHELIAL CELLS authKW 682777 4% 60% 6
4 DRUG DISPOSIT PHARMACOKINET address 667927 6% 39% 9
5 CLONIDINE DERIVED DRUGS authKW 379323 1% 100% 2
6 LIPOPHILIC BASIC DRUGS authKW 379323 1% 100% 2
7 INFLUX TRANSPORT authKW 252881 1% 67% 2
8 TR IBRB2 CELLS authKW 252881 1% 67% 2
9 BLOOD RETINAL BARRIER authKW 247141 12% 7% 19
10 AMINO ACID TRANSPORTER B 0 B authKW 189662 1% 100% 1

Web of Science journal categories


Rank Term Chi square Shr. of publ. in
class containing
term		 Class's shr. of
term's tot. occurrences		 #P with
term in
class
1 Pharmacology & Pharmacy 1571 57% 0% 92
2 Ophthalmology 507 16% 0% 25
3 Chemistry, Medicinal 159 10% 0% 16
4 Neurosciences 62 14% 0% 22
5 Chemistry, Multidisciplinary 58 15% 0% 24
6 Medicine, Research & Experimental 38 7% 0% 11
7 Physiology 21 5% 0% 8
8 Hematology 15 4% 0% 6
9 Biochemistry & Molecular Biology 14 12% 0% 20
10 Peripheral Vascular Diseases 5 2% 0% 4

Address terms


Rank Term Chi square Shr. of publ. in
class containing
term		 Class's shr. of
term's tot. occurrences		 #P with
term in
class
1 DRUG DISPOSIT PHARMACOKINET 667927 6% 39% 9
2 CNRS UMR 7157 PHARM 189662 1% 100% 1
3 CNRSINSERMU705UMR 7157 PHARM PHARMACO 189662 1% 100% 1
4 CREMO CHUL 189662 1% 100% 1
5 DRUG DISPOSIT PHAMRACOKINET 189662 1% 100% 1
6 IMIVERL CNRS 9218UMR 1023 189662 1% 100% 1
7 RECH BIOPHARMACEUT 189662 1% 100% 1
8 VARIABILITE REPONSE PSYCHOTROPES 170691 2% 30% 3
9 MOL BIOPHARM GENET 132419 6% 8% 9
10 MED PHARMACEUT SCI 99397 24% 1% 39

Journals


Rank Term Chi square Shr. of publ. in
class containing
term		 Class's shr. of
term's tot. occurrences		 #P with
term in
class
1 DRUG METABOLISM AND PHARMACOKINETICS 9458 4% 1% 6
2 JOURNAL OF PHARMACEUTICAL SCIENCES 2854 8% 0% 13
3 BIOLOGICAL & PHARMACEUTICAL BULLETIN 1780 6% 0% 9
4 PHARMACEUTICAL RESEARCH 1510 5% 0% 8
5 MOLECULAR PHARMACEUTICS 1500 3% 0% 5
6 EXPERIMENTAL EYE RESEARCH 1413 4% 0% 7
7 PHARMACEUTISCH WEEKBLAD-SCIENTIFIC EDITION 1329 1% 0% 2
8 JOURNAL OF PHARMACY AND PHARMACOLOGY 1154 4% 0% 7
9 MICROVASCULAR RESEARCH 1139 2% 0% 4
10 JOURNAL OF CEREBRAL BLOOD FLOW AND METABOLISM 883 3% 0% 5

Author Key Words


Rank Term Chi square Shr. of publ. in
class containing
term		 Class's shr. of
term's tot. occurrences		 #P with
term in
class		 LCSH search Wikipedia search
1 INNER BLOOD RETINAL BARRIER 2445267 12% 68% 19 Search INNER+BLOOD+RETINAL+BARRIER Search INNER+BLOOD+RETINAL+BARRIER
2 PROTON COUPLED ORGANIC CATION ANTIPORTER 758646 2% 100% 4 Search PROTON+COUPLED+ORGANIC+CATION+ANTIPORTER Search PROTON+COUPLED+ORGANIC+CATION+ANTIPORTER
3 RETINAL CAPILLARY ENDOTHELIAL CELLS 682777 4% 60% 6 Search RETINAL+CAPILLARY+ENDOTHELIAL+CELLS Search RETINAL+CAPILLARY+ENDOTHELIAL+CELLS
4 CLONIDINE DERIVED DRUGS 379323 1% 100% 2 Search CLONIDINE+DERIVED+DRUGS Search CLONIDINE+DERIVED+DRUGS
5 LIPOPHILIC BASIC DRUGS 379323 1% 100% 2 Search LIPOPHILIC+BASIC+DRUGS Search LIPOPHILIC+BASIC+DRUGS
6 INFLUX TRANSPORT 252881 1% 67% 2 Search INFLUX+TRANSPORT Search INFLUX+TRANSPORT
7 TR IBRB2 CELLS 252881 1% 67% 2 Search TR+IBRB2+CELLS Search TR+IBRB2+CELLS
8 BLOOD RETINAL BARRIER 247141 12% 7% 19 Search BLOOD+RETINAL+BARRIER Search BLOOD+RETINAL+BARRIER
9 AMINO ACID TRANSPORTER B 0 B 189662 1% 100% 1 Search AMINO+ACID+TRANSPORTER+B+0+B Search AMINO+ACID+TRANSPORTER+B+0+B
10 BLOOD TO RETINA TRANSPORT 189662 1% 100% 1 Search BLOOD+TO+RETINA+TRANSPORT Search BLOOD+TO+RETINA+TRANSPORT

Core articles
The table includes core articles in the class. The following variables is taken into account for the relevance score of an article in a cluster c:
(1) Number of references referring to publications in the class.
(2) Share of total number of active references referring to publications in the class.
(3) Age of the article. New articles get higher score than old articles.
(4) Citation rate, normalized to year.


Rank Reference # ref.
in cl.		 Shr. of ref. in
cl.		 Citations
1 KUBO, Y , TSUCHIYAMA, A , SHIMIZU, Y , AKANUMA, S , HOSOYA, K , (2014) INVOLVEMENT OF CARRIER-MEDIATED TRANSPORT IN THE RETINAL UPTAKE OF CLONIDINE AT THE INNER BLOOD-RETINAL BARRIER.MOLECULAR PHARMACEUTICS. VOL. 11. ISSUE 10. P. 3747 -3753 23 66% 1
2 KUBO, Y , (2015) CARRIER-MEDIATED TRANSPORT OF CATIONIC DRUGS ACROSS THE BLOOD-TISSUE BARRIER.YAKUGAKU ZASSHI-JOURNAL OF THE PHARMACEUTICAL SOCIETY OF JAPAN. VOL. 135. ISSUE 10. P. 1135 -1140 17 77% 0
3 KUBO, Y , KUSAGAWA, Y , TACHIKAWA, M , AKANUMA, S , HOSOYA, K , (2013) INVOLVEMENT OF A NOVEL ORGANIC CATION TRANSPORTER IN VERAPAMIL TRANSPORT ACROSS THE INNER BLOOD-RETINAL BARRIER.PHARMACEUTICAL RESEARCH. VOL. 30. ISSUE 3. P. 847-856 25 48% 7
4 KUBO, Y , SHIMIZU, Y , KUSAGAWA, Y , AKANUMA, SI , HOSOYA, KI , (2013) PROPRANOLOL TRANSPORT ACROSS THE INNER BLOOD-RETINAL BARRIER: POTENTIAL INVOLVEMENT OF A NOVEL ORGANIC CATION TRANSPORTER.JOURNAL OF PHARMACEUTICAL SCIENCES. VOL. 102. ISSUE 9. P. 3332-3342 24 49% 9
5 HOSOYA, K , TOMI, M , TACHIKAWA, M , (2011) STRATEGIES FOR THERAPY OF RETINAL DISEASES USING SYSTEMIC DRUG DELIVERY: RELEVANCE OF TRANSPORTERS AT THE BLOOD--RETINAL BARRIER.EXPERT OPINION ON DRUG DELIVERY. VOL. 8. ISSUE 12. P. 1571 -1587 34 30% 10
6 HOSOYA, K , TACHIKAWA, M , (2013) THE INNER BLOOD-RETINAL BARRIER MOLECULAR STRUCTURE AND TRANSPORT BIOLOGY.BIOLOGY AND REGULATION OF BLOOD-TISSUE BARRIERS. VOL. 763. ISSUE . P. 85 -104 31 31% 4
7 KUBO, Y , FUKUI, E , AKANUMA, SI , TACHIKAWA, M , HOSOYA, KI , (2012) APPLICATION OF MEMBRANE PERMEABILITY EVALUATED IN IN VITRO ANALYSES TO ESTIMATE BLOOD-RETINAL BARRIER PERMEABILITY.JOURNAL OF PHARMACEUTICAL SCIENCES. VOL. 101. ISSUE 7. P. 2596-2605 21 46% 1
8 KUBO, Y , OBATA, A , AKANUMA, S , HOSOYA, K , (2015) IMPACT OF CATIONIC AMINO ACID TRANSPORTER 1 ON BLOOD-RETINAL BARRIER TRANSPORT OF L-ORNITHINE.INVESTIGATIVE OPHTHALMOLOGY & VISUAL SCIENCE. VOL. 56. ISSUE 10. P. 5925 -5932 15 44% 1
9 HOSOYA, K , YAMAMOTO, A , AKANUMA, S , TACHIKAWA, M , (2010) LIPOPHILICITY AND TRANSPORTER INFLUENCE ON BLOOD-RETINAL BARRIER PERMEABILITY: A COMPARISON WITH BLOOD-BRAIN BARRIER PERMEABILITY.PHARMACEUTICAL RESEARCH. VOL. 27. ISSUE 12. P. 2715-2724 18 40% 9
10 KUBO, Y , TOMISE, A , TSUCHIYAMA, A , AKANUMA, S , HOSOYA, K , (2014) INVOLVEMENT OF THE CARRIER-MEDIATED PROCESS IN THE RETINA-TO-BLOOD TRANSPORT OF SPERMINE AT THE INNER BLOOD-RETINAL BARRIER.EXPERIMENTAL EYE RESEARCH. VOL. 124. ISSUE . P. 17 -23 20 33% 0

Classes with closest relation at Level 1


Rank Class id link
1 20325 LOGBB//BLOOD BRAIN PARTITIONING//PAMPA BBB
2 3077 ORGANIC CATION TRANSPORTER//ORGANIC ANION TRANSPORTER//ORGANIC CATION TRANSPORT
3 26883 NORTILIDINE//TILIDINE//DIPHENHYDRAMINE
4 30687 KANGEN KARYU//DAN GUA FANG//ALDOSE REDUCTASE INHIBITOR ONO 2235
5 33869 TEMPERATURE SENSITIVE SIMIAN VIRUS 40 LARGE T ANTIGEN//GASTRIC MUCIN SECRETION//TEMPERATURE SENSITIVE SV40 LARGE T ANTIGEN
6 16403 HEMICHOLINIUM 3//AF64A//CHOLINE TRANSPORT
7 4989 BLOOD BRAIN BARRIER//BBB//TIGHT JUNCTION
8 15135 BLOOD AQUEOUS BARRIER//AQUEOUS FLARE//VITREOUS FLUOROPHOTOMETRY
9 26970 MIZORIBINE//ORAL MIZORIBINE PULSE THERAPY//LS180 CELL
10 7391 MORPHINE 6 GLUCURONIDE//OXYCODONE//MORPHINE 3 GLUCURONIDE

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