Class information for:
Level 1: SIGMA RECEPTOR//SIGMA1 RECEPTOR//SIGMA 1 RECEPTOR

Basic class information

Class id #P Avg. number of
references
Database coverage
of references
3540 1962 41.6 81%



Bar chart of Publication_year

Last years might be incomplete

Hierarchy of classes

The table includes all classes above and classes immediately below the current class.



Cluster id Level Cluster label #P
11 4 NEUROSCIENCES//CLINICAL NEUROLOGY//NEUROL 1112395
100 3       NEUROSCIENCES//METABOTROPIC GLUTAMATE RECEPTOR//HIPPOCAMPUS 73970
488 2             SIGMA RECEPTOR//NMDA RECEPTOR//PHENCYCLIDINE 15502
3540 1                   SIGMA RECEPTOR//SIGMA1 RECEPTOR//SIGMA 1 RECEPTOR 1962

Terms with highest relevance score



rank Term termType Chi square Shr. of publ. in
class containing
term
Class's shr. of
term's tot. occurrences
#P with
term in
class
1 SIGMA RECEPTOR authKW 4823073 21% 75% 411
2 SIGMA1 RECEPTOR authKW 1638615 6% 90% 117
3 SIGMA 1 RECEPTOR authKW 1593865 6% 81% 126
4 SIGMA LIGANDS authKW 752340 3% 82% 59
5 PENTAZOCINE authKW 500109 4% 43% 75
6 SIGMA BINDING SITES authKW 488787 2% 90% 35
7 SA4503 authKW 435725 1% 100% 28
8 SIGMA 2 RECEPTOR authKW 430670 2% 86% 32
9 PHARMAZEUT MED CHEM address 405108 5% 29% 91
10 SIGMA RECEPTOR LIGANDS authKW 324192 1% 83% 25

Web of Science journal categories



Rank Term Chi square Shr. of publ. in
class containing
term
Class's shr. of
term's tot. occurrences
#P with
term in
class
1 Pharmacology & Pharmacy 10009 42% 0% 827
2 Chemistry, Medicinal 6725 18% 0% 349
3 Neurosciences 3640 27% 0% 520
4 Chemistry, Organic 401 8% 0% 158
5 Psychiatry 301 6% 0% 109
6 Behavioral Sciences 168 3% 0% 50
7 Radiology, Nuclear Medicine & Medical Imaging 108 4% 0% 82
8 Biochemistry & Molecular Biology 105 11% 0% 215
9 Medicine, Research & Experimental 64 3% 0% 66
10 Clinical Neurology 56 4% 0% 78

Address terms



Rank Term Chi square Shr. of publ. in
class containing
term
Class's shr. of
term's tot. occurrences
#P with
term in
class
1 PHARMAZEUT MED CHEM 405108 5% 29% 91
2 CELLULAR PATHOBIOL SECT 235187 1% 66% 23
3 BEHAV NEUROPHARMACOL GRP 234338 1% 94% 16
4 CELLULAR PATHOBIOL UNIT 132601 1% 61% 14
5 UNIT RECEPTOR BIOCHEM PHARMACOL 129677 1% 83% 10
6 DRUG DISCOVERY PRECLIN DEV 106086 1% 45% 15
7 PHARMAZEUT MED CHEM WESTFAL 93370 0% 100% 6
8 MU REACTOR 90029 0% 64% 9
9 POSITRON MED 70702 2% 13% 36
10 UNIT MOSE DEA 60548 1% 32% 12

Journals



Rank Term Chi square Shr. of publ. in
class containing
term
Class's shr. of
term's tot. occurrences
#P with
term in
class
1 EUROPEAN JOURNAL OF PHARMACOLOGY 23878 11% 1% 208
2 JOURNAL OF MEDICINAL CHEMISTRY 10317 6% 1% 120
3 JOURNAL OF PHARMACOLOGY AND EXPERIMENTAL THERAPEUTICS 9316 6% 1% 113
4 SYNAPSE 7157 2% 1% 39
5 NUCLEAR MEDICINE AND BIOLOGY 7051 2% 1% 41
6 BIOORGANIC & MEDICINAL CHEMISTRY 3543 3% 0% 55
7 NEUROPHARMACOLOGY 3007 2% 0% 43
8 ANNALS OF GENERAL PSYCHIATRY 2886 0% 3% 7
9 POLISH JOURNAL OF PHARMACOLOGY 2836 1% 2% 11
10 EUROPEAN JOURNAL OF MEDICINAL CHEMISTRY 2229 2% 0% 37

Author Key Words



Rank Term Chi square Shr. of publ. in
class containing
term
Class's shr. of
term's tot. occurrences
#P with
term in
class
LCSH search Wikipedia search
1 SIGMA RECEPTOR 4823073 21% 75% 411 Search SIGMA+RECEPTOR Search SIGMA+RECEPTOR
2 SIGMA1 RECEPTOR 1638615 6% 90% 117 Search SIGMA1+RECEPTOR Search SIGMA1+RECEPTOR
3 SIGMA 1 RECEPTOR 1593865 6% 81% 126 Search SIGMA+1+RECEPTOR Search SIGMA+1+RECEPTOR
4 SIGMA LIGANDS 752340 3% 82% 59 Search SIGMA+LIGANDS Search SIGMA+LIGANDS
5 PENTAZOCINE 500109 4% 43% 75 Search PENTAZOCINE Search PENTAZOCINE
6 SIGMA BINDING SITES 488787 2% 90% 35 Search SIGMA+BINDING+SITES Search SIGMA+BINDING+SITES
7 SA4503 435725 1% 100% 28 Search SA4503 Search SA4503
8 SIGMA 2 RECEPTOR 430670 2% 86% 32 Search SIGMA+2+RECEPTOR Search SIGMA+2+RECEPTOR
9 SIGMA RECEPTOR LIGANDS 324192 1% 83% 25 Search SIGMA+RECEPTOR+LIGANDS Search SIGMA+RECEPTOR+LIGANDS
10 C 11SA4503 280885 1% 95% 19 Search C+11SA4503 Search C+11SA4503

Core articles

The table includes core articles in the class. The following variables is taken into account for the relevance score of an article in a cluster c:
(1) Number of references referring to publications in the class.
(2) Share of total number of active references referring to publications in the class.
(3) Age of the article. New articles get higher score than old articles.
(4) Citation rate, normalized to year.



Rank Reference # ref. in
cl.
Shr. of ref. in
cl.
Citations
1 LEHMKUHL, K , JIA, H , WUNSCH, B , BRUST, P , DEUTHER-CONRAD, W , (2014) MOLECULAR IMAGING OF ALPHA(1) RECEPTORS IN VIVO: CURRENT STATUS AND PERSPECTIVES.CURRENT MEDICINAL CHEMISTRY. VOL. 21. ISSUE 1. P. 35 -69 228 84% 14
2 ROUSSEAUX, CG , GREENE, SF , (2016) SIGMA RECEPTORS [SIGMA RS]: BIOLOGY IN NORMAL AND DISEASED STATES.JOURNAL OF RECEPTORS AND SIGNAL TRANSDUCTION. VOL. 36. ISSUE 4. P. 327 -388 423 43% 1
3 MAURICE, T , SU, TP , (2009) THE PHARMACOLOGY OF SIGMA-1 RECEPTORS.PHARMACOLOGY & THERAPEUTICS. VOL. 124. ISSUE 2. P. 195 -206 146 90% 289
4 BANISTER, SD , KASSIOU, M , (2012) THE THERAPEUTIC POTENTIAL OF SIGMA (SIGMA) RECEPTORS FOR THE TREATMENT OF CENTRAL NERVOUS SYSTEM DISEASES: EVALUATION OF THE EVIDENCE.CURRENT PHARMACEUTICAL DESIGN. VOL. 18. ISSUE 7. P. 884 -901 206 85% 19
5 COBOS, EJ , ENTRENA, JM , NIETO, FR , CENDAN, CM , DEL POZO, E , (2008) PHARMACOLOGY AND THERAPEUTIC POTENTIAL OF SIGMA(1) RECEPTOR LIGANDS.CURRENT NEUROPHARMACOLOGY. VOL. 6. ISSUE 4. P. 344 -366 169 80% 163
6 VAN WAARDE, A , RYBCZYNSKA, AA , RAMAKRISHNAN, NK , ISHIWATA, K , ELSINGA, PH , DIERCKX, RAJO , (2010) SIGMA RECEPTORS IN ONCOLOGY: THERAPEUTIC AND DIAGNOSTIC APPLICATIONS OF SIGMA LIGANDS.CURRENT PHARMACEUTICAL DESIGN. VOL. 16. ISSUE 31. P. 3519-3537 159 92% 49
7 GUITART, X , CODONY, X , MONROY, X , (2004) SIGMA RECEPTORS: BIOLOGY AND THERAPEUTIC POTENTIAL.PSYCHOPHARMACOLOGY. VOL. 174. ISSUE 3. P. 301 -319 170 90% 159
8 CHU, UB , RUOHO, AE , (2016) BIOCHEMICAL PHARMACOLOGY OF THE SIGMA-1 RECEPTOR.MOLECULAR PHARMACOLOGY. VOL. 89. ISSUE 1. P. 142 -153 92 84% 9
9 HUANG, YS , LU, HL , ZHANG, LJ , WU, ZW , (2014) SIGMA-2 RECEPTOR LIGANDS AND THEIR PERSPECTIVES IN CANCER DIAGNOSIS AND THERAPY.MEDICINAL RESEARCH REVIEWS. VOL. 34. ISSUE 3. P. 532 -566 122 88% 20
10 SU, TP , SU, TC , TSAI, SY , NAKAMURA, Y , (2016) THE SIGMA-1 RECEPTOR AS A PLURIPOTENT MODULATOR IN LIVING SYSTEMS.TRENDS IN PHARMACOLOGICAL SCIENCES. VOL. 37. ISSUE 4. P. 262 -278 103 82% 6

Classes with closest relation at Level 1



Rank Class id link
1 6946 PHENCYCLIDINE//METAPHIT//BTCP
2 17688 DEXTROMETHORPHAN//COUGH AND COLD MEDICATIONS//DIMEMORFAN
3 31267 HERBICIDINS//2 3 DIHYDRO 1 4 DIOXIN//2 AMINOBENZOBTHIOPHENE 3 CARBOXYLATES
4 30338 IMIDAZO4 5 GQUINOLINES//PYRIDO2 3 GQUINOXALINES//TRIAZOLO4 5 GQUINOLINES
5 22490 PGRMC1//MEMBRANE PROGESTIN RECEPTOR//PAQR3
6 35143 BENZENESELENINIC ACID//N N N TRIPHENYLGUANIDINE//2 PYRIDINESELENINATE
7 20544 MELANOMA IMAGING//IMAGERIE MOL THER IE VECTORISEE//ALPHA MELANOCYTE STIMULATING HORMONE HYBRID PEPTIDE
8 6033 ARCAINE//POLYAMINES//SPERMINE
9 1599 NEUROSTEROIDS//ALLOPREGNANOLONE//NEUROACTIVE STEROIDS
10 30065 POLYANTIGENIC IMMUNOMODULATOR//V HA RAS ONCOGENE//RETROVIROL EPIGENET

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