Class information for:
Level 1: AIRE//APECED//AUTOIMMUNE REGULATOR

Basic class information
Class id #P Avg. number of
references		 Database coverage
of references
5236 1652 41.5 84%


Bar chart of Publication_year

Last years might be incomplete

Hierarchy of classes
The table includes all classes above and classes immediately below the current class.


Cluster id Level Cluster label #P
0 4 BIOCHEMISTRY & MOLECULAR BIOLOGY//CELL BIOLOGY//ONCOLOGY 4064930
284 3       POLYCYSTIC OVARY SYNDROME//ENDOCRINOLOGY & METABOLISM//CORTISOL 42633
2373 2             ADRENAL INSUFFICIENCY//AIRE//APECED 4304
5236 1                   AIRE//APECED//AUTOIMMUNE REGULATOR 1652

Terms with highest relevance score


rank Term termType Chi square Shr. of publ. in
class containing
term		 Class's shr. of
term's tot. occurrences		 #P with
term in
class
1 AIRE authKW 1454287 7% 68% 116
2 APECED authKW 1330691 5% 86% 84
3 AUTOIMMUNE REGULATOR authKW 449555 2% 81% 30
4 FOXN1 authKW 419293 2% 69% 33
5 CHRONIC MUCOCUTANEOUS CANDIDIASIS authKW 337932 2% 57% 32
6 AIRE GENE authKW 299407 1% 90% 18
7 CENTRAL TOLERANCE authKW 272664 2% 51% 29
8 PROMISCUOUS GENE EXPRESSION authKW 272185 1% 82% 18
9 AUTOIMMUNE POLYENDOCRINOPATHY CANDIDIASIS ECTODERMAL DYSTROPHY authKW 259903 1% 94% 15
10 APS1 authKW 241498 1% 93% 14

Web of Science journal categories


Rank Term Chi square Shr. of publ. in
class containing
term		 Class's shr. of
term's tot. occurrences		 #P with
term in
class
1 Immunology 13223 43% 0% 711
2 Endocrinology & Metabolism 2660 16% 0% 270
3 Developmental Biology 390 3% 0% 57
4 Medicine, General & Internal 359 8% 0% 139
5 Cell Biology 249 8% 0% 137
6 Pediatrics 225 5% 0% 83
7 Medicine, Research & Experimental 199 5% 0% 87
8 Genetics & Heredity 183 6% 0% 96
9 Dermatology 123 3% 0% 43
10 Cell & Tissue Engineering 79 1% 0% 12

Address terms


Rank Term Chi square Shr. of publ. in
class containing
term		 Class's shr. of
term's tot. occurrences		 #P with
term in
class
1 DEV IMMUNOL 86445 3% 9% 55
2 GEN MOL PATHOL 76076 2% 15% 27
3 FIRS S 56172 1% 20% 15
4 PAEDIAT IMMUNOL GENET OPERAT UNIT 55446 0% 100% 3
5 MOL IMMUNOGENET GRP 55428 1% 25% 12
6 OSPED MICROCITEM 47519 0% 43% 6
7 INTERNAL MED ENDOCRINE METAB SCI 46573 1% 23% 11
8 BIOCHEM MED BIOTECHNOL CEINGE 36964 0% 100% 2
9 DISCIPLINES GENET MOL BIOL DMEF 36964 0% 100% 2
10 IST SEMEIOT MED CHAIR ENDOCRINOL 36964 0% 100% 2

Journals


Rank Term Chi square Shr. of publ. in
class containing
term		 Class's shr. of
term's tot. occurrences		 #P with
term in
class
1 JOURNAL OF CLINICAL ENDOCRINOLOGY & METABOLISM 6077 5% 0% 89
2 NATURE IMMUNOLOGY 4395 1% 1% 23
3 EUROPEAN JOURNAL OF IMMUNOLOGY 4030 3% 0% 54
4 JOURNAL OF AUTOIMMUNITY 3895 1% 1% 23
5 JOURNAL OF IMMUNOLOGY 3681 6% 0% 105
6 IMMUNITY 3330 2% 1% 25
7 FRONTIERS IN IMMUNOLOGY 2772 1% 1% 21
8 NATURE REVIEWS IMMUNOLOGY 2478 1% 1% 12
9 JOURNAL OF PEDIATRIC ENDOCRINOLOGY & METABOLISM 1838 1% 1% 19
10 JOURNAL OF EXPERIMENTAL MEDICINE 1793 2% 0% 35

Author Key Words


Rank Term Chi square Shr. of publ. in
class containing
term		 Class's shr. of
term's tot. occurrences		 #P with
term in
class		 LCSH search Wikipedia search
1 AIRE 1454287 7% 68% 116 Search AIRE Search AIRE
2 APECED 1330691 5% 86% 84 Search APECED Search APECED
3 AUTOIMMUNE REGULATOR 449555 2% 81% 30 Search AUTOIMMUNE+REGULATOR Search AUTOIMMUNE+REGULATOR
4 FOXN1 419293 2% 69% 33 Search FOXN1 Search FOXN1
5 CHRONIC MUCOCUTANEOUS CANDIDIASIS 337932 2% 57% 32 Search CHRONIC+MUCOCUTANEOUS+CANDIDIASIS Search CHRONIC+MUCOCUTANEOUS+CANDIDIASIS
6 AIRE GENE 299407 1% 90% 18 Search AIRE+GENE Search AIRE+GENE
7 CENTRAL TOLERANCE 272664 2% 51% 29 Search CENTRAL+TOLERANCE Search CENTRAL+TOLERANCE
8 PROMISCUOUS GENE EXPRESSION 272185 1% 82% 18 Search PROMISCUOUS+GENE+EXPRESSION Search PROMISCUOUS+GENE+EXPRESSION
9 AUTOIMMUNE POLYENDOCRINOPATHY CANDIDIASIS ECTODERMAL DYSTROPHY 259903 1% 94% 15 Search AUTOIMMUNE+POLYENDOCRINOPATHY+CANDIDIASIS+ECTODERMAL+DYSTROPHY Search AUTOIMMUNE+POLYENDOCRINOPATHY+CANDIDIASIS+ECTODERMAL+DYSTROPHY
10 APS1 241498 1% 93% 14 Search APS1 Search APS1

Core articles
The table includes core articles in the class. The following variables is taken into account for the relevance score of an article in a cluster c:
(1) Number of references referring to publications in the class.
(2) Share of total number of active references referring to publications in the class.
(3) Age of the article. New articles get higher score than old articles.
(4) Citation rate, normalized to year.


Rank Reference # ref. in
cl.		 Shr. of ref. in
cl.		 Citations
1 KISAND, K , PETERSON, P , (2015) AUTOIMMUNE POLYENDOCRINOPATHY CANDIDIASIS ECTODERMAL DYSTROPHY.JOURNAL OF CLINICAL IMMUNOLOGY. VOL. 35. ISSUE 5. P. 463 -478 126 89% 5
2 MATHIS, D , BENOIST, C , (2009) AIRE.ANNUAL REVIEW OF IMMUNOLOGY. VOL. 27. ISSUE . P. 287-312 102 71% 300
3 ANDERSON, MS , SU, MA , (2016) AIRE EXPANDS: NEW ROLES IN IMMUNE TOLERANCE AND BEYOND.NATURE REVIEWS IMMUNOLOGY. VOL. 16. ISSUE 4. P. 247 -258 79 87% 5
4 ABRAMSON, J , HUSEBYE, ES , (2016) AUTOIMMUNE REGULATOR AND SELF-TOLERANCE - MOLECULAR AND CLINICAL ASPECTS.IMMUNOLOGICAL REVIEWS. VOL. 271. ISSUE 1. P. 127 -140 83 82% 5
5 NITTA, T , SUZUKI, H , (2016) THYMIC STROMAL CELL SUBSETS FOR T CELL DEVELOPMENT.CELLULAR AND MOLECULAR LIFE SCIENCES. VOL. 73. ISSUE 5. P. 1021 -1037 136 62% 0
6 KISAND, K , PETERSON, P , (2011) AUTOIMMUNE POLYENDOCRINOPATHY CANDIDIASIS ECTODERMAL DYSTROPHY: KNOWN AND NOVEL ASPECTS OF THE SYNDROME.YEAR IN HUMAN AND MEDICAL GENETICS: INBORN ERRORS OF IMMUNITY II. VOL. 1246. ISSUE . P. 77 -91 104 83% 23
7 PETERSON, P , ORG, T , REBANE, A , (2008) TRANSCRIPTIONAL REGULATION BY AIRE: MOLECULAR MECHANISMS OF CENTRAL TOLERANCE.NATURE REVIEWS IMMUNOLOGY. VOL. 8. ISSUE 12. P. 948-957 104 79% 92
8 ARSTILA, TP , JARVE, H , (2013) HUMAN APECED; A SICK THYMUS SYNDROME?.FRONTIERS IN IMMUNOLOGY. VOL. 4. ISSUE . P. - 84 94% 12
9 PERNIOLA, R , MUSCO, G , (2014) THE BIOPHYSICAL AND BIOCHEMICAL PROPERTIES OF THE AUTOIMMUNE REGULATOR (AIRE) PROTEIN.BIOCHIMICA ET BIOPHYSICA ACTA-MOLECULAR BASIS OF DISEASE. VOL. 1842. ISSUE 2. P. 326 -337 96 77% 8
10 DE MARTINO, L , CAPALBO, D , IMPRODA, N , D'ELIA, F , DI MASE, R , D'ASSANTE, R , D'ACUNZO, I , PIGNATA, C , SALERNO, M , (2013) APECD: A PARADIGM OF COMPLEX INTERACTIONS BETWEEN GENETIC BACKGROUND AND SUSCEPTIBILITY FACTORS.FRONTIERS IN IMMUNOLOGY. VOL. 4. ISSUE . P. - 91 83% 12

Classes with closest relation at Level 1


Rank Class id link
1 24235 ANTI TG//FDN SALVATORE MAUGERI ENDOCRINE DISRUPTORS//IST RICOVERO CURA CARATTERE SCIIST SUPER PREVE
2 10888 IMMUNE RECONSTITUTION//TREC//LYMPHOCYTE RECOVERY
3 9379 PAX5//EBF//LINEAGE COMMITMENT
4 11660 ADRENAL INSUFFICIENCY//ADDISONS DISEASE//ADRENAL CRISIS
5 4314 T CELL DEVELOPMENT//THYMIC SELECTION//PRE T CELL RECEPTOR
6 23941 HDR SYNDROME//HYPOPARATHYROIDISM//KENNY CAFFEY SYNDROME
7 10084 PREMATURE OVARIAN FAILURE//PRIMARY OVARIAN INSUFFICIENCY//PREMATURE MENOPAUSE
8 3928 THYMUS//THYMIC NURSE CELLS//THYMIC MICROENVIRONMENT
9 11080 LYMPHOCYTIC HYPOPHYSITIS//SHEEHANS SYNDROME//HYPOPHYSITIS
10 21656 AUTOIMMUNE GASTRITIS//PARIETAL CELL ANTIBODIES//ANTIGASTRIC AUTOANTIBODIES

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