Class information for:
Level 1: ATENOLOL//4 HYDROXYPROPRANOLOL//METOPROLOL

Basic class information
Class id #P Avg. number of
references		 Database coverage
of references
7286 1385 23.6 55%


Bar chart of Publication_year

Last years might be incomplete

Hierarchy of classes
The table includes all classes above and classes immediately below the current class.


Cluster id Level Cluster label #P
8 4 CARDIAC & CARDIOVASCULAR SYSTEM//PERIPHERAL VASCULAR DISEASES//CARDIOL 1276458
522 3       MAGNESIUM-BULLETIN//MAGNESIUM RESEARCH//MAGNESIUM 20526
878 2             NEBIVOLOL//CARVEDILOL//BETA BLOCKERS 11463
7286 1                   ATENOLOL//4 HYDROXYPROPRANOLOL//METOPROLOL 1385

Terms with highest relevance score


rank Term termType Chi square Shr. of publ. in
class containing
term		 Class's shr. of
term's tot. occurrences		 #P with
term in
class
1 ATENOLOL authKW 237158 7% 11% 97
2 4 HYDROXYPROPRANOLOL authKW 128261 1% 73% 8
3 METOPROLOL authKW 114620 5% 8% 64
4 ALPHA HYDROXYMETOPROLOL authKW 98198 1% 64% 7
5 PROPRANOLOL authKW 90050 7% 4% 95
6 OXPRENOLOL authKW 78441 1% 32% 11
7 LABETALOL HYDROCHLORIDE authKW 68889 0% 63% 5
8 CDNBD authKW 66137 0% 100% 3
9 EDUC NATIONALITIES address 66137 0% 100% 3
10 PROPRANOLOL DETERMINATION authKW 66137 0% 100% 3

Web of Science journal categories


Rank Term Chi square Shr. of publ. in
class containing
term		 Class's shr. of
term's tot. occurrences		 #P with
term in
class
1 Chemistry, Analytical 15669 45% 0% 630
2 Pharmacology & Pharmacy 9582 49% 0% 673
3 Biochemical Research Methods 2236 14% 0% 195
4 Chemistry, Medicinal 1556 11% 0% 146
5 Chemistry, Multidisciplinary 275 12% 0% 166
6 Spectroscopy 90 3% 0% 40
7 Toxicology 72 3% 0% 41
8 Electrochemistry 19 2% 0% 23
9 Medical Laboratory Technology 18 1% 0% 12
10 Chemistry, Organic 11 3% 0% 43

Address terms


Rank Term Chi square Shr. of publ. in
class containing
term		 Class's shr. of
term's tot. occurrences		 #P with
term in
class
1 EDUC NATIONALITIES 66137 0% 100% 3
2 CLIN PHARM PHARMACOTHER Y UNITHLTH 44091 0% 100% 2
3 ADV VRM DIPLOMA MED TECHNOL 22046 0% 100% 1
4 ANAIYT DEV 22046 0% 100% 1
5 ANALYT CHEM LIFE SCIMINIST EDUC CHINA 22046 0% 100% 1
6 BIOL FARMACIA 22046 0% 100% 1
7 BIOMETABOL ANAL 22046 0% 100% 1
8 CHEM THEORY DRUGS TOXICOL 22046 0% 100% 1
9 CLIN PHARMACOL SECTCLIN HOSP 22046 0% 100% 1
10 COFIQUI 22046 0% 100% 1

Journals


Rank Term Chi square Shr. of publ. in
class containing
term		 Class's shr. of
term's tot. occurrences		 #P with
term in
class
1 JOURNAL OF CHROMATOGRAPHY-BIOMEDICAL APPLICATIONS 16581 4% 1% 52
2 JOURNAL OF CHROMATOGRAPHY 15248 8% 1% 113
3 JOURNAL OF PHARMACEUTICAL AND BIOMEDICAL ANALYSIS 9246 5% 1% 68
4 CLINICAL PHARMACOLOGY & THERAPEUTICS 7952 3% 1% 46
5 CHIRALITY 6903 2% 1% 31
6 BIOMEDICAL CHROMATOGRAPHY 5598 2% 1% 30
7 BRITISH JOURNAL OF CLINICAL PHARMACOLOGY 4737 3% 1% 42
8 DRUG METABOLISM AND DISPOSITION 4412 3% 1% 39
9 JOURNAL OF CHROMATOGRAPHY B-ANALYTICAL TECHNOLOGIES IN THE BIOMEDICAL AND LIFE SCIENCES 3030 3% 0% 41
10 BIOPHARMACEUTICS & DRUG DISPOSITION 2903 1% 1% 16

Author Key Words


Rank Term Chi square Shr. of publ. in
class containing
term		 Class's shr. of
term's tot. occurrences		 #P with
term in
class		 LCSH search Wikipedia search
1 ATENOLOL 237158 7% 11% 97 Search ATENOLOL Search ATENOLOL
2 4 HYDROXYPROPRANOLOL 128261 1% 73% 8 Search 4+HYDROXYPROPRANOLOL Search 4+HYDROXYPROPRANOLOL
3 METOPROLOL 114620 5% 8% 64 Search METOPROLOL Search METOPROLOL
4 ALPHA HYDROXYMETOPROLOL 98198 1% 64% 7 Search ALPHA+HYDROXYMETOPROLOL Search ALPHA+HYDROXYMETOPROLOL
5 PROPRANOLOL 90050 7% 4% 95 Search PROPRANOLOL Search PROPRANOLOL
6 OXPRENOLOL 78441 1% 32% 11 Search OXPRENOLOL Search OXPRENOLOL
7 LABETALOL HYDROCHLORIDE 68889 0% 63% 5 Search LABETALOL+HYDROCHLORIDE Search LABETALOL+HYDROCHLORIDE
8 CDNBD 66137 0% 100% 3 Search CDNBD Search CDNBD
9 PROPRANOLOL DETERMINATION 66137 0% 100% 3 Search PROPRANOLOL+DETERMINATION Search PROPRANOLOL+DETERMINATION
10 ACEBUTOLOL HYDROCHLORIDE 55109 0% 50% 5 Search ACEBUTOLOL+HYDROCHLORIDE Search ACEBUTOLOL+HYDROCHLORIDE

Core articles
The table includes core articles in the class. The following variables is taken into account for the relevance score of an article in a cluster c:
(1) Number of references referring to publications in the class.
(2) Share of total number of active references referring to publications in the class.
(3) Age of the article. New articles get higher score than old articles.
(4) Citation rate, normalized to year.


Rank Reference # ref.
in cl.		 Shr. of ref. in
cl.		 Citations
1 EL-DIDAMONY, AM , SHEHATA, AM , (2014) SPECTROPHOTOMETRIC DETERMINATION OF BETA-ADRENERGIC ANTAGONISTS DRUGS VIA ION-PAIR COMPLEX FORMATION USING MO AND EBT.OPTICS AND SPECTROSCOPY. VOL. 117. ISSUE 3. P. 492 -499 29 67% 2
2 DAVIES, CL , (1990) CHROMATOGRAPHY OF BETA-ADRENERGIC BLOCKING-AGENTS.JOURNAL OF CHROMATOGRAPHY-BIOMEDICAL APPLICATIONS. VOL. 531. ISSUE . P. 131-180 95 43% 42
3 EL-DIDAMONY, AM , ERFAN, EAH , (2011) SPECTROPHOTOMETRIC DETERMINATION OF BETA-BLOCKER DRUGS BY OXIDATION WITH BROMATE-BROMIDE MIXTURE AND ITS ANALYTICAL APPLICATION TO PHARMACEUTICAL PREPARATIONS.SPECTROSCOPY-BIOMEDICAL APPLICATIONS. VOL. 25. ISSUE 6. P. 303 -315 27 73% 2
4 SOLTES, L , (1989) HIGH-PERFORMANCE LIQUID-CHROMATOGRAPHIC DETERMINATION OF BETA-ADRENOCEPTOR BLOCKING-AGENTS IN BODY-FLUIDS.BIOMEDICAL CHROMATOGRAPHY. VOL. 3. ISSUE 4. P. 139-152 69 61% 6
5 MEHVAR, R , BROCKS, DR , (2001) STEREOSPECIFIC PHARMACOKINETICS AND PHARMACODYNAMICS OF BETA-ADRENERGIC BLOCKERS IN HUMANS.JOURNAL OF PHARMACY AND PHARMACEUTICAL SCIENCES. VOL. 4. ISSUE 2. P. 185-200 37 56% 149
6 CERQUEIRA, PM , CESARINO, EJ , BERTUCCI, C , BONATO, PS , LANCHOTE, VL , (2003) STEREOSELECTIVE METABOLISM OF METOPROLOL: ENANTIOSELECTIVITY OF ALPHA-HYDROXYMETOPROLOL IN PLASMA AND URINE.CHIRALITY. VOL. 15. ISSUE 6. P. 542-549 27 77% 14
7 EGGINGER, G , LINDNER, W , VANDENBOSCH, C , MASSART, DL , (1993) ENANTIOSELECTIVE BIOANALYSIS OF BETA-BLOCKING-AGENTS - FOCUS ON ATENOLOL, BETAXOLOL, CARVEDILOL, METOPROLOL, PINDOLOL, PROPRANOLOL AND SOTALOL.BIOMEDICAL CHROMATOGRAPHY. VOL. 7. ISSUE 6. P. 277-295 55 50% 35
8 PRASHANTH, KN , BASAVAIAH, K , (2012) SENSITIVE SPECTROPHOTOMETRIC DETERMINATION OF ATENOLOL IN PHARMACEUTICAL FORMULATIONS USING BROMATE-BROMIDE MIXTURE AS AN ECO-FRIENDLY BROMINATING AGENT.JOURNAL OF ANALYTICAL METHODS IN CHEMISTRY. VOL. . ISSUE . P. - 24 65% 1
9 DYAS, AM , (1992) THE CHIRAL CHROMATOGRAPHIC-SEPARATION OF BETA-ADRENOCEPTOR BLOCKING-DRUGS.JOURNAL OF PHARMACEUTICAL AND BIOMEDICAL ANALYSIS. VOL. 10. ISSUE 6. P. 383-404 58 49% 19
10 PARTANI, P , MODHAVE, Y , GURULE, S , KHUROO, A , MONIF, T , (2009) SIMULTANEOUS DETERMINATION OF PROPRANOLOL AND 4-HYDROXY PROPRANOLOL IN HUMAN PLASMA BY SOLID PHASE EXTRACTION AND LIQUID CHROMATOGRAPHY/ELECTROSPRAY TANDEM MASS SPECTROMETRY.JOURNAL OF PHARMACEUTICAL AND BIOMEDICAL ANALYSIS. VOL. 50. ISSUE 5. P. 966-976 18 86% 26

Classes with closest relation at Level 1


Rank Class id link
1 23518 POLYVINYLACETATE POVIDONE EXCIPIENT//RECEPTOR OCCUPANCY THEORY//CAS 318 98 9
2 18811 BISOPROLOL//BISOPROLOL EFFICACY//INTRAVESICAL BCG INSTILLATION
3 37680 BRIMONIDINE TARTRATE//4 HYDROXY 5 METHOXYNAPHTHALENE 1 YL ACETATE//ACID BASE DISSOCIATION CONSTANT
4 13765 CHIRAL LIGAND EXCHANGE CHROMATOGRAPHY//LIGAND EXCHANGE CHROMATOGRAPHY//CHIRAL DERIVATIZING REAGENTS
5 7760 HYDROCHLOROTHIAZIDE//AMLODIPINE BESYLATE//LOSARTAN POTASSIUM
6 18202 CANRENONE//TRIAMTERENE//7 ALPHA THIOMETHYLSPIROLACTONE
7 18416 NORVERAPAMIL//VERAPAMIL//CLIN PHARMACOL GERIATR MED
8 19737 SEMI MICROCOLUMN LIQUID CHROMATOGRAPHY//RESTRICTED ACCESS MEDIA//MIXED FUNCTIONAL PHASE
9 12676 AMOSULALOL//DILEVALOL//AARHUS CTY HOSP MED 1
10 30907 ABS SANTA COLOMA GRAMENET 6//ACID BASE EXCRETION//BETA2 ANDRENERGIC RECEPTOR GENE

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