Class information for:
Level 1: HUMAN PLACENTAL MICROSOMES//19 OXYGENATION//SUICIDE SUBSTRATE

Basic class information
Class id #P Avg. number of
references		 Database coverage
of references
8508 1246 25.6 37%


Bar chart of Publication_year

Last years might be incomplete

Hierarchy of classes
The table includes all classes above and classes immediately below the current class.


Cluster id Level Cluster label #P
3 4 PLANT SCIENCES//AGRONOMY//FOOD SCIENCE & TECHNOLOGY 1882812
553 3       BRASSINOSTEROIDS//NA K ATPASE//OUABAIN 17999
1738 2             BRASSINOSTEROIDS//24 EPIBRASSINOLIDE//BRASSINOLIDE 6531
8508 1                   HUMAN PLACENTAL MICROSOMES//19 OXYGENATION//SUICIDE SUBSTRATE 1246

Terms with highest relevance score


rank Term termType Chi square Shr. of publ. in
class containing
term		 Class's shr. of
term's tot. occurrences		 #P with
term in
class
1 HUMAN PLACENTAL MICROSOMES authKW 252782 1% 74% 14
2 19 OXYGENATION authKW 196041 1% 100% 8
3 SUICIDE SUBSTRATE authKW 158070 2% 32% 20
4 WESTPHALEN REARRANGEMENT authKW 122525 0% 100% 5
5 16 ALPHA HYDROXYANDROSTENEDIONE authKW 98020 0% 100% 4
6 ESTUDOS FARMACEUT address 91905 2% 17% 22
7 PHARMACEUT CHEM GRP address 85761 1% 50% 7
8 COLLECTION OF CZECHOSLOVAK CHEMICAL COMMUNICATIONS journal 79848 12% 2% 154
9 BIOCHEMICAL AROMATIZATION authKW 73515 0% 100% 3
10 FOSSIL BIOMARKERS authKW 73515 0% 100% 3

Web of Science journal categories


Rank Term Chi square Shr. of publ. in
class containing
term		 Class's shr. of
term's tot. occurrences		 #P with
term in
class
1 Chemistry, Organic 5280 30% 0% 374
2 Chemistry, Multidisciplinary 3468 35% 0% 437
3 Endocrinology & Metabolism 2445 18% 0% 223
4 Chemistry, Medicinal 768 8% 0% 100
5 Biochemistry & Molecular Biology 745 24% 0% 295
6 Crystallography 159 4% 0% 46
7 Pharmacology & Pharmacy 38 6% 0% 75
8 Spectroscopy 0 1% 0% 11
9 Biophysics -0 1% 0% 14
10 Integrative & Complementary Medicine -0 0% 0% 1

Address terms


Rank Term Chi square Shr. of publ. in
class containing
term		 Class's shr. of
term's tot. occurrences		 #P with
term in
class
1 ESTUDOS FARMACEUT 91905 2% 17% 22
2 PHARMACEUT CHEM GRP 85761 1% 50% 7
3 CHEM PHYS ENVIRONM SCI 40571 3% 4% 39
4 QUIM FARMACEUT 40127 3% 5% 33
5 CEF PHARM 32672 0% 67% 2
6 BRANCH TORY 2 24505 0% 100% 1
7 BROMATOL PHARMACOGNOSY ANALYT SCI GRP 24505 0% 100% 1
8 CHEM PHYS ENVIROMN SCI 24505 0% 100% 1
9 CHEM YODOGAWA KU 24505 0% 100% 1
10 EP 9 BIOCHIM BIOL MOL 24505 0% 100% 1

Journals


Rank Term Chi square Shr. of publ. in
class containing
term		 Class's shr. of
term's tot. occurrences		 #P with
term in
class
1 COLLECTION OF CZECHOSLOVAK CHEMICAL COMMUNICATIONS 79848 12% 2% 154
2 STEROIDS 69626 9% 3% 111
3 JOURNAL OF THE CHEMICAL SOCIETY-PERKIN TRANSACTIONS 1 22517 8% 1% 102
4 JOURNAL OF STEROID BIOCHEMISTRY AND MOLECULAR BIOLOGY 19596 7% 1% 85
5 JOURNAL OF CHEMICAL RESEARCH 10959 4% 1% 51
6 NATURAL PRODUCT REPORTS 7634 2% 1% 21
7 JOURNAL OF CHEMICAL RESEARCH-S 4989 2% 1% 25
8 INDIAN JOURNAL OF CHEMISTRY SECTION B-ORGANIC CHEMISTRY INCLUDING MEDICINAL CHEMISTRY 2499 3% 0% 32
9 JOURNAL FUR PRAKTISCHE CHEMIE 1329 1% 1% 8
10 KHIMIYA PRIRODNYKH SOEDINENII 1160 1% 0% 13

Author Key Words


Rank Term Chi square Shr. of publ. in
class containing
term		 Class's shr. of
term's tot. occurrences		 #P with
term in
class		 LCSH search Wikipedia search
1 HUMAN PLACENTAL MICROSOMES 252782 1% 74% 14 Search HUMAN+PLACENTAL+MICROSOMES Search HUMAN+PLACENTAL+MICROSOMES
2 19 OXYGENATION 196041 1% 100% 8 Search 19+OXYGENATION Search 19+OXYGENATION
3 SUICIDE SUBSTRATE 158070 2% 32% 20 Search SUICIDE+SUBSTRATE Search SUICIDE+SUBSTRATE
4 WESTPHALEN REARRANGEMENT 122525 0% 100% 5 Search WESTPHALEN+REARRANGEMENT Search WESTPHALEN+REARRANGEMENT
5 16 ALPHA HYDROXYANDROSTENEDIONE 98020 0% 100% 4 Search 16+ALPHA+HYDROXYANDROSTENEDIONE Search 16+ALPHA+HYDROXYANDROSTENEDIONE
6 BIOCHEMICAL AROMATIZATION 73515 0% 100% 3 Search BIOCHEMICAL+AROMATIZATION Search BIOCHEMICAL+AROMATIZATION
7 FOSSIL BIOMARKERS 73515 0% 100% 3 Search FOSSIL+BIOMARKERS Search FOSSIL+BIOMARKERS
8 HUMAN PLACENTAL AROMATASE 73515 0% 100% 3 Search HUMAN+PLACENTAL+AROMATASE Search HUMAN+PLACENTAL+AROMATASE
9 DELTA5 STEROIDS 73509 0% 50% 6 Search DELTA5+STEROIDS Search DELTA5+STEROIDS
10 TIME DEPENDENT INACTIVATION 73509 0% 50% 6 Search TIME+DEPENDENT+INACTIVATION Search TIME+DEPENDENT+INACTIVATION

Core articles
The table includes core articles in the class. The following variables is taken into account for the relevance score of an article in a cluster c:
(1) Number of references referring to publications in the class.
(2) Share of total number of active references referring to publications in the class.
(3) Age of the article. New articles get higher score than old articles.
(4) Citation rate, normalized to year.


Rank Reference # ref.
in cl.		 Shr. of ref. in
cl.		 Citations
1 YADAV, MR , BARMADE, MA , TAMBOLI, RS , MURUMKAR, PR , (2015) DEVELOPING STEROIDAL AROMATASE INHIBITORS-AN EFFECTIVE ARMAMENT TO WIN THE BATTLE AGAINST BREAST CANCER.EUROPEAN JOURNAL OF MEDICINAL CHEMISTRY. VOL. 105. ISSUE . P. 1 -38 85 41% 8
2 LEVINA, IS , (1998) SUBSTITUTED ANDROSTANES AS AROMATASE INHIBITORS.USPEKHI KHIMII. VOL. 67. ISSUE 11. P. 1068-1093 60 67% 3
3 STEPHAN, E , (2006) SYNTHESIS OF MODIFIED STEROIDS IN THE ANDROSTANE AND ANDROSTENE SERIES.ORGANIC PREPARATIONS AND PROCEDURES INTERNATIONAL. VOL. 38. ISSUE 3. P. 217-305 70 33% 6
4 NUMAZAWA, M , NAGAOKA, M , HANDA, W , OGAWA, Y , MATSUOKA, S , (2007) STUDIES DIRECTED TOWARDS A MECHANISTIC EVALUATION OF INACTIVATION OF AROMATASE BY THE SUICIDE SUBSTRATES ANDROSTA-1,4-DIENE-3,17-DIONES AND ITS 6-ENE DERIVATIVES - AROMATASE INACTIVATION BY THE 19-SUBSTITUTED DERIVATIVES AND THEIR ENZYMIC AROMATIZATION.JOURNAL OF STEROID BIOCHEMISTRY AND MOLECULAR BIOLOGY. VOL. 107. ISSUE 3-5. P. 211-219 25 89% 7
5 NUMAZAWA, M , WATARI, Y , KOMATSU, S , YAMASHITA, K , NAGAOKA, M , (2008) AROMATIZATION OF ANDROSTENEDIONE AND 16 ALPHA-HYDROXYANDROSTENEDIONE IN HUMAN PLACENTAL MICROSOMES - KINETIC ANALYSIS OF INHIBITION BY THE 19-OXYGENATED AND 3-DEOXY ANALOGS.STEROIDS. VOL. 73. ISSUE 12. P. 1262 -1269 21 95% 3
6 NUMAZAWA, M , (1998) DEVELOPMENT OF AROMATASE INHIBITORS AND ANALYSIS OF THEIR INHIBITORY ACTIVITIES.YAKUGAKU ZASSHI-JOURNAL OF THE PHARMACEUTICAL SOCIETY OF JAPAN. VOL. 118. ISSUE 12. P. 539 -553 29 94% 0
7 NAGAOKA, M , WATARI, Y , YAJIMA, H , TSUKIOKA, K , MUROI, Y , YAMADA, K , NUMAZAWA, M , (2003) STRUCTURE-ACTIVITY RELATIONSHIPS OF 3-DEOXY ANDROGENS AS AROMATASE INHIBITORS. SYNTHESIS AND BIOCHEMICAL STUDIES OF 4-SUBSTITUTED 4-ENE AND 5-ENE STEROIDS.STEROIDS. VOL. 68. ISSUE 6. P. 533 -542 23 96% 15
8 COLE, PA , ROBINSON, CH , (1990) MECHANISM AND INHIBITION OF CYTOCHROME-P-450 AROMATASE.JOURNAL OF MEDICINAL CHEMISTRY. VOL. 33. ISSUE 11. P. 2933-2942 45 62% 204
9 TAKAHASHI, M , YAMASHITA, K , NUMAZAWA, M , (2010) PROBING THE BINDING POCKET OF THE ACTIVE SITE OF AROMATASE WITH 2-PHENYLALIPHATIC ANDROSTA-1,4-DIENE-3,17-DIONE STEROIDS.STEROIDS. VOL. 75. ISSUE 4-5. P. 330 -337 19 90% 8
10 TAKAHASHI, M , HANDA, W , UMETA, H , ISHIKAWA, S , YAMASHITA, K , NUMAZAWA, M , (2009) AROMATASE INACTIVATION BY 2-SUBSTITUTED DERIVATIVES OF THE SUICIDE SUBSTRATE ANDROSTA-1,4-DIENE-3,17-DIONE.JOURNAL OF STEROID BIOCHEMISTRY AND MOLECULAR BIOLOGY. VOL. 116. ISSUE 3-5. P. 191 -199 22 81% 2

Classes with closest relation at Level 1


Rank Class id link
1 24051 PENTACYCLIC STEROIDS//IMIDE REDUCTION//13 16 DIAZASTEROIDS
2 22853 14 ALPHA 15 ALPHA METHYLENE ESTRADIOL//SIMMONS SMITH ADDITION//SPIRO STEROIDS
3 17767 PENTARANES//GRP CHEM STEROIDS OXYLIPINES//PROGESTERONE ANALOGS
4 13518 STEROIDS//STEROIDAL OXIMES//HETEROSTEROIDS
5 20736 ERYTHROPHLEUM FORDII//CASSAINE DITERPENOID AMIDES//PERHYDROINDENES
6 30711 HOLARRHENA PUBESCENS//SCHEFFLERA VENULOSA//SINGLE CRYSTAL X RAY DIFFRACTOMETER
7 5097 AROMATASE INHIBITORS//ANASTROZOLE//EXEMESTANE
8 25262 CEPHALOSTATIN//RITTERAZINE//CEPHALOSTATIN 1
9 24189 ANTEDRUG//ANTIINFLAMMATORY//TIPREDANE
10 10772 AROMATASE//JOURNAL OF STEROID BIOCHEMISTRY AND MOLECULAR BIOLOGY//METAB CANC

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