Class information for:
Level 1: TRICYCLIC ANTIDEPRESSANTS//NORTRIPTYLINE//DOXEPIN

Basic class information
Class id #P Avg. number of
references		 Database coverage
of references
8529 1244 26.2 47%


Bar chart of Publication_year

Last years might be incomplete

Hierarchy of classes
The table includes all classes above and classes immediately below the current class.


Cluster id Level Cluster label #P
1 4 ECONOMICS//EDUCATION & EDUCATIONAL RESEARCH//PSYCHOL 3876184
154 3       PSYCHIATRY//ALEXITHYMIA//PSYCHIAT 62481
207 2             PSYCHIATRY//ANTIDEPRESSANTS//DEPRESSION 21074
8529 1                   TRICYCLIC ANTIDEPRESSANTS//NORTRIPTYLINE//DOXEPIN 1244

Terms with highest relevance score


rank Term termType Chi square Shr. of publ. in
class containing
term		 Class's shr. of
term's tot. occurrences		 #P with
term in
class
1 TRICYCLIC ANTIDEPRESSANTS authKW 146394 5% 9% 67
2 NORTRIPTYLINE authKW 137648 3% 15% 37
3 DOXEPIN authKW 129805 2% 23% 23
4 DESMETHYLMIANSERIN authKW 102267 0% 83% 5
5 AMITRIPTYLINE authKW 80511 4% 6% 51
6 DOTHIEPIN HYDROCHLORIDE authKW 78541 0% 80% 4
7 HYDROXYDESIPRAMINE authKW 73633 0% 100% 3
8 TRIMIPRAMINE authKW 67980 1% 21% 13
9 AMITRIPTYLINE HCL authKW 65449 0% 67% 4
10 10 HYDROXYNORTRIPTYLINE authKW 55224 0% 75% 3

Web of Science journal categories


Rank Term Chi square Shr. of publ. in
class containing
term		 Class's shr. of
term's tot. occurrences		 #P with
term in
class
1 Pharmacology & Pharmacy 7114 44% 0% 553
2 Psychiatry 6972 27% 0% 341
3 Chemistry, Analytical 4975 28% 0% 345
4 Medical Laboratory Technology 4261 10% 0% 123
5 Toxicology 1319 10% 0% 129
6 Biochemical Research Methods 605 8% 0% 102
7 Psychology, Clinical 137 3% 0% 35
8 Neurosciences 121 8% 0% 104
9 Chemistry, Medicinal 96 3% 0% 42
10 Psychology 61 2% 0% 25

Address terms


Rank Term Chi square Shr. of publ. in
class containing
term		 Class's shr. of
term's tot. occurrences		 #P with
term in
class
1 ANAL FOODSTUFFS DRUGS WATER TOX 24544 0% 100% 1
2 ANALYT CHEM BROMATOL TOXICOL 24544 0% 100% 1
3 BIOL PSYCHIAT BASIC PSYCHIAT 24544 0% 100% 1
4 CLIN PHARMACOL PROPEDEUT INTERNAL DIS 24544 0% 100% 1
5 FARM FARM PASEO DESAN VICENTE SN 24544 0% 100% 1
6 FARMVOS CLIN PHARMACOL DRUG DEV 24544 0% 100% 1
7 GPO BOX 2476V 24544 0% 100% 1
8 GRP MAT ELE OQUIM METDOS ELE OANAL 24544 0% 100% 1
9 GRP MAT ELE OQUIM METODOS ELE OANAL 24544 0% 100% 1
10 HKRANKENHAUS PSYCHIATPSYCHOTHER IE GGMBH 24544 0% 100% 1

Journals


Rank Term Chi square Shr. of publ. in
class containing
term		 Class's shr. of
term's tot. occurrences		 #P with
term in
class
1 THERAPEUTIC DRUG MONITORING 28573 5% 2% 66
2 JOURNAL OF CLINICAL PSYCHOPHARMACOLOGY 19145 4% 2% 46
3 JOURNAL OF CHROMATOGRAPHY-BIOMEDICAL APPLICATIONS 6971 3% 1% 32
4 PHARMACOPSYCHIATRY 6443 2% 1% 23
5 COMMUNICATIONS IN PSYCHOPHARMACOLOGY 5943 0% 6% 4
6 JOURNAL OF ANALYTICAL TOXICOLOGY 5333 2% 1% 27
7 CLINICAL PHARMACOKINETICS 5012 2% 1% 22
8 JOURNAL OF CLINICAL PSYCHIATRY 4195 3% 0% 35
9 PSYCHOPHARMAKOTHERAPIE 3983 1% 2% 9
10 CLINICAL PHARMACOLOGY & THERAPEUTICS 3749 2% 1% 30

Author Key Words


Rank Term Chi square Shr. of publ. in
class containing
term		 Class's shr. of
term's tot. occurrences		 #P with
term in
class		 LCSH search Wikipedia search
1 TRICYCLIC ANTIDEPRESSANTS 146394 5% 9% 67 Search TRICYCLIC+ANTIDEPRESSANTS Search TRICYCLIC+ANTIDEPRESSANTS
2 NORTRIPTYLINE 137648 3% 15% 37 Search NORTRIPTYLINE Search NORTRIPTYLINE
3 DOXEPIN 129805 2% 23% 23 Search DOXEPIN Search DOXEPIN
4 DESMETHYLMIANSERIN 102267 0% 83% 5 Search DESMETHYLMIANSERIN Search DESMETHYLMIANSERIN
5 AMITRIPTYLINE 80511 4% 6% 51 Search AMITRIPTYLINE Search AMITRIPTYLINE
6 DOTHIEPIN HYDROCHLORIDE 78541 0% 80% 4 Search DOTHIEPIN+HYDROCHLORIDE Search DOTHIEPIN+HYDROCHLORIDE
7 HYDROXYDESIPRAMINE 73633 0% 100% 3 Search HYDROXYDESIPRAMINE Search HYDROXYDESIPRAMINE
8 TRIMIPRAMINE 67980 1% 21% 13 Search TRIMIPRAMINE Search TRIMIPRAMINE
9 AMITRIPTYLINE HCL 65449 0% 67% 4 Search AMITRIPTYLINE+HCL Search AMITRIPTYLINE+HCL
10 10 HYDROXYNORTRIPTYLINE 55224 0% 75% 3 Search 10+HYDROXYNORTRIPTYLINE Search 10+HYDROXYNORTRIPTYLINE

Core articles
The table includes core articles in the class. The following variables is taken into account for the relevance score of an article in a cluster c:
(1) Number of references referring to publications in the class.
(2) Share of total number of active references referring to publications in the class.
(3) Age of the article. New articles get higher score than old articles.
(4) Citation rate, normalized to year.


Rank Reference # ref.
in cl.		 Shr. of ref. in
cl.		 Citations
1 UDDIN, MN , SAMANIDOU, VF , PAPADOYANNIS, IN , (2011) BIO-SAMPLE PREPARATION AND ANALYTICAL METHODS FOR THE DETERMINATION OF TRICYCLIC ANTIDEPRESSANTS.BIOANALYSIS. VOL. 3. ISSUE 1. P. 97 -118 62 47% 6
2 GUPTA, RN , (1992) DRUG LEVEL MONITORING - ANTIDEPRESSANTS.JOURNAL OF CHROMATOGRAPHY-BIOMEDICAL APPLICATIONS. VOL. 576. ISSUE 2. P. 183-211 60 67% 35
3 ULRICH, S , LAUTER, J , (2002) COMPREHENSIVE SURVEY OF THE RELATIONSHIP BETWEEN SERUM CONCENTRATION AND THERAPEUTIC EFFECT OF AMITRIPTYLINE IN DEPRESSION.CLINICAL PHARMACOKINETICS. VOL. 41. ISSUE 11. P. 853-876 35 76% 27
4 FURLANUT, M , BENETELLO, P , SPINA, E , (1993) PHARMACOKINETIC OPTIMIZATION OF TRICYCLIC ANTIDEPRESSANT THERAPY.CLINICAL PHARMACOKINETICS. VOL. 24. ISSUE 4. P. 301-318 66 51% 24
5 SAMANIDOU, VF , NIKA, MK , PAPADOYANNIS, IN , (2008) HPLC AS A TOOL IN MEDICINAL CHEMISTRY FOR THE MONITORING OF TRICYCLIC ANTIDEPRESSANTS IN BIOFLUIDS.MINI-REVIEWS IN MEDICINAL CHEMISTRY. VOL. 8. ISSUE 3. P. 256-275 32 64% 4
6 THONGNOPNUA, P , KARNJANAVES, K , (2008) THE RAPID SIMULTANEOUS TRICYCLIC ANTIDEPRESSANT DETERMINATION BY PLASMA DEPROTEINIZATION AND LIQUID CHROMATOGRAPHY.ASIAN BIOMEDICINE. VOL. 2. ISSUE 4. P. 305 -318 26 79% 1
7 RUDORFER, MV , POTTER, WZ , (1999) METABOLISM OF TRICYCLIC ANTIDEPRESSANTS.CELLULAR AND MOLECULAR NEUROBIOLOGY. VOL. 19. ISSUE 3. P. 373-409 61 41% 35
8 NORMAN, TR , MAGUIRE, KP , (1985) ANALYSIS OF TRICYCLIC ANTIDEPRESSANT DRUGS IN PLASMA AND SERUM BY CHROMATOGRAPHIC TECHNIQUES.JOURNAL OF CHROMATOGRAPHY. VOL. 340. ISSUE MAY. P. 173-197 55 86% 35
9 ORSULAK, PJ , (1989) THERAPEUTIC MONITORING OF ANTIDEPRESSANT DRUGS - GUIDELINES UPDATED.THERAPEUTIC DRUG MONITORING. VOL. 11. ISSUE 5. P. 497-507 51 71% 37
10 DEEPAKUMARI, HN , PRASHANTH, MK , KUMAR, BCV , REVANASIDDAPPA, HD , (2015) HIGHLY SENSITIVE AND VALIDATED SPECTROPHOTOMETRIC TECHNIQUE FOR THE ASSAY OF SOME ANTIDEPRESSANT DRUGS.JOURNAL OF APPLIED SPECTROSCOPY. VOL. 81. ISSUE 6. P. 1004 -1011 18 86% 2

Classes with closest relation at Level 1


Rank Class id link
1 10622 CYCLIC ANTIDEPRESSANT//AMITRIPTYLINE POISONING//TRICYCLIC ANTIDEPRESSANTS
2 12254 NORFLUOXETINE//CITALOPRAM//FLUOXETINE
3 19698 TRAZODONE//NEFAZODONE//ETOPERIDONE
4 13979 PHENOTHIAZINE DRUGS//PROMETHAZINE HYDROCHLORIDE//PROMETHAZINE
5 1626 CYP2D6//DEBRISOQUINE//CYP2D6 POLYMORPHISM
6 29476 AMINEPTINE HCL//DECREASED POSITIVE MOOD SYMPTOMS//DOG MAN
7 23948 MIRTAZAPINE//ORG 3770//MIRTAZAPINE ORG 3770
8 28445 COMPANY SPONSORED POST AUTHORIZATION STUDIES//POST AUTHORIZATION STUDIES//DRUG UTILIZATION OBSERVATION STUDY
9 13903 SYSTEMATIC TOXICOLOGICAL ANALYSIS//GENERAL UNKNOWN SCREENING//TANDEM MASS SPECTRAL LIBRARY
10 7609 9 HYDROXYRISPERIDONE//NORCLOZAPINE//CLOZAPINE

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