Class information for:
Level 1: LEBERS HEREDITARY OPTIC NEUROPATHY//LHON//LEBER HEREDITARY OPTIC NEUROPATHY

Basic class information
Class id #P Avg. number of
references		 Database coverage
of references
9055 1191 35.5 79%


Bar chart of Publication_year

Last years might be incomplete

Hierarchy of classes
The table includes all classes above and classes immediately below the current class.


Cluster id Level Cluster label #P
0 4 BIOCHEMISTRY & MOLECULAR BIOLOGY//CELL BIOLOGY//ONCOLOGY 4064930
271 3       MITOCHONDRIA//MITOCHONDRIAL GENOME//MITOCHONDRIAL DNA PART A 43930
381 2             MITOCHONDRIA//MELAS//MITOCHONDRIAL DISEASE 17103
9055 1                   LEBERS HEREDITARY OPTIC NEUROPATHY//LHON//LEBER HEREDITARY OPTIC NEUROPATHY 1191

Terms with highest relevance score


rank Term termType Chi square Shr. of publ. in
class containing
term		 Class's shr. of
term's tot. occurrences		 #P with
term in
class
1 LEBERS HEREDITARY OPTIC NEUROPATHY authKW 3716769 14% 86% 169
2 LHON authKW 2342972 9% 84% 109
3 LEBER HEREDITARY OPTIC NEUROPATHY authKW 1684177 7% 83% 79
4 DOMINANT OPTIC ATROPHY authKW 598893 2% 81% 29
5 AUTOSOMAL DOMINANT OPTIC ATROPHY authKW 534092 2% 83% 25
6 OPA1 authKW 462078 4% 35% 52
7 ADOA authKW 288838 1% 87% 13
8 MITOCHONDRIAL DNA MUTATION authKW 278774 4% 25% 43
9 LEBER authKW 205087 1% 67% 12
10 OPTIC NEUROPATHY authKW 190102 6% 11% 67

Web of Science journal categories


Rank Term Chi square Shr. of publ. in
class containing
term		 Class's shr. of
term's tot. occurrences		 #P with
term in
class
1 Ophthalmology 26624 40% 0% 479
2 Clinical Neurology 4468 27% 0% 326
3 Genetics & Heredity 2748 21% 0% 248
4 Neurosciences 604 15% 0% 182
5 Biochemistry & Molecular Biology 116 13% 0% 153
6 Biophysics 101 4% 0% 53
7 Medicine, Research & Experimental 72 4% 0% 49
8 Cell Biology 28 5% 0% 56
9 Pediatrics 9 2% 0% 24
10 Neuroimaging 6 0% 0% 5

Address terms


Rank Term Chi square Shr. of publ. in
class containing
term		 Class's shr. of
term's tot. occurrences		 #P with
term in
class
1 SIRIRAJ NEUROGENET NETWORK 106818 0% 83% 5
2 U694 81220 1% 21% 15
3 ATTARDI MITOCHONDRIAL BIOMED 70485 1% 25% 11
4 CARDIFF EYE UNIT 62552 1% 20% 12
5 CARDIFF NEUROSCI 51274 0% 100% 2
6 GIUSEPPE ATTARDI MITOCHONDRIAL BIOMED 51274 0% 100% 2
7 INSERM E0018 51274 0% 100% 2
8 NEUROFTALMOL 51274 0% 100% 2
9 NEUROL CLIN NEUROL NEUROGENET SECT 51274 0% 100% 2
10 OPHTHALMOL NEUROL NEUROL SURG 51274 0% 100% 2

Journals


Rank Term Chi square Shr. of publ. in
class containing
term		 Class's shr. of
term's tot. occurrences		 #P with
term in
class
1 JOURNAL OF NEURO-OPHTHALMOLOGY 26592 3% 3% 35
2 CLINICAL NEUROSCIENCE 17807 1% 6% 11
3 NEURO-OPHTHALMOLOGY 15611 2% 2% 28
4 OPHTHALMIC PAEDIATRICS AND GENETICS 11377 1% 3% 13
5 MITOCHONDRION 7786 2% 2% 18
6 OPHTHALMIC GENETICS 6160 1% 2% 12
7 MOLECULAR VISION 6074 2% 1% 28
8 JOURNAL OF CLINICAL NEURO-OPHTHALMOLOGY 4486 1% 2% 10
9 INVESTIGATIVE OPHTHALMOLOGY & VISUAL SCIENCE 3520 4% 0% 52
10 JAPANESE JOURNAL OF OPHTHALMOLOGY 3413 2% 1% 19

Author Key Words


Rank Term Chi square Shr. of publ. in
class containing
term		 Class's shr. of
term's tot. occurrences		 #P with
term in
class		 LCSH search Wikipedia search
1 LEBERS HEREDITARY OPTIC NEUROPATHY 3716769 14% 86% 169 Search LEBERS+HEREDITARY+OPTIC+NEUROPATHY Search LEBERS+HEREDITARY+OPTIC+NEUROPATHY
2 LHON 2342972 9% 84% 109 Search LHON Search LHON
3 LEBER HEREDITARY OPTIC NEUROPATHY 1684177 7% 83% 79 Search LEBER+HEREDITARY+OPTIC+NEUROPATHY Search LEBER+HEREDITARY+OPTIC+NEUROPATHY
4 DOMINANT OPTIC ATROPHY 598893 2% 81% 29 Search DOMINANT+OPTIC+ATROPHY Search DOMINANT+OPTIC+ATROPHY
5 AUTOSOMAL DOMINANT OPTIC ATROPHY 534092 2% 83% 25 Search AUTOSOMAL+DOMINANT+OPTIC+ATROPHY Search AUTOSOMAL+DOMINANT+OPTIC+ATROPHY
6 OPA1 462078 4% 35% 52 Search OPA1 Search OPA1
7 ADOA 288838 1% 87% 13 Search ADOA Search ADOA
8 MITOCHONDRIAL DNA MUTATION 278774 4% 25% 43 Search MITOCHONDRIAL+DNA+MUTATION Search MITOCHONDRIAL+DNA+MUTATION
9 LEBER 205087 1% 67% 12 Search LEBER Search LEBER
10 OPTIC NEUROPATHY 190102 6% 11% 67 Search OPTIC+NEUROPATHY Search OPTIC+NEUROPATHY

Core articles
The table includes core articles in the class. The following variables is taken into account for the relevance score of an article in a cluster c:
(1) Number of references referring to publications in the class.
(2) Share of total number of active references referring to publications in the class.
(3) Age of the article. New articles get higher score than old articles.
(4) Citation rate, normalized to year.


Rank Reference # ref. in
cl.		 Shr. of ref. in
cl.		 Citations
1 YU-WAI-MAN, P , GRIFFITHS, PG , HUDSON, G , CHINNERY, PF , (2009) INHERITED MITOCHONDRIAL OPTIC NEUROPATHIES.JOURNAL OF MEDICAL GENETICS. VOL. 46. ISSUE 3. P. 145 -158 169 79% 130
2 YU-WAI-MAN, P , GRIFFITHS, PG , CHINNERY, PF , (2011) MITOCHONDRIAL OPTIC NEUROPATHIES - DISEASE MECHANISMS AND THERAPEUTIC STRATEGIES.PROGRESS IN RETINAL AND EYE RESEARCH. VOL. 30. ISSUE 2. P. 81 -114 215 51% 130
3 YEN, MY , WANG, AG , WEI, YH , (2006) LEBER'S HEREDITARY OPTIC NEUROPATHY: A MULTIFACTORIAL DISEASE.PROGRESS IN RETINAL AND EYE RESEARCH. VOL. 25. ISSUE 4. P. 381-396 108 87% 73
4 MAN, PYW , TURNBULL, DM , CHINNERY, PF , (2002) LEBER HEREDITARY OPTIC NEUROPATHY.JOURNAL OF MEDICAL GENETICS. VOL. 39. ISSUE 3. P. 162-169 100 91% 172
5 KOILKONDA, RD , GUY, J , (2011) LEBER'S HEREDITARY OPTIC NEUROPATHY-GENE THERAPY: FROM BENCHTOP TO BEDSIDE.JOURNAL OF OPHTHALMOLOGY. VOL. . ISSUE . P. - 98 75% 15
6 RASOOL, N , LESSELL, S , CESTARI, DM , (2016) LEBER HEREDITARY OPTIC NEUROPATHY: BRINGING THE LAB TO THE CLINIC.SEMINARS IN OPHTHALMOLOGY. VOL. 31. ISSUE 1-2. P. 107 -116 69 84% 2
7 GALLENMULLER, C , KLOPSTOCK, T , (2014) LEBER'S HEREDITARY OPTIC NEUROPATHY - PHENOTYPE, GENETICS, THERAPEUTIC OPTIONS.KLINISCHE MONATSBLATTER FUR AUGENHEILKUNDE. VOL. 231. ISSUE 3. P. 216 -221 74 94% 1
8 CARELLI, V , ROSS-CISNEROS, FN , SADUN, AA , (2004) MITOCHONDRIAL DYSFUNCTION AS A CAUSE OF OPTIC NEUROPATHIES.PROGRESS IN RETINAL AND EYE RESEARCH. VOL. 23. ISSUE 1. P. 53-89 123 45% 338
9 MARESCA, A , CAPORALI, L , STROBBE, D , ZANNA, C , MALAVOLTA, D , LA MORGIA, C , VALENTINO, ML , CARELLI, V , (2014) GENETIC BASIS OF MITOCHONDRIAL OPTIC NEUROPATHIES.CURRENT MOLECULAR MEDICINE. VOL. 14. ISSUE 8. P. 985 -992 72 76% 1
10 YU-WAI-MAN, P , (2015) THERAPEUTIC APPROACHES TO INHERITED OPTIC NEUROPATHIES.SEMINARS IN NEUROLOGY. VOL. 35. ISSUE 5. P. 578 -586 64 75% 2

Classes with closest relation at Level 1


Rank Class id link
1 31726 ETHAMBUTOL//TOXIC OPTIC NEUROPATHY//ETHAMBUTOL OPTIC NEUROPATHY
2 21506 MITOCHONDRIAL HAPLOGROUPS//MITOCHONDRIAL DNA POLYMORPHISM//PERSONALIZED PREVENTIVE MEDICINE
3 77 MELAS//MITOCHONDRIAL DISEASE//MITOCHONDRIAL ENCEPHALOMYOPATHY
4 29169 ECUAC DIFERENCIALES//CRISIS ECONOMICA//DETERMINANTES DE SALUD
5 24942 3 HYDROXY 3 METHYLGLUTARIC ACIDURIA//3 METHYLGLUTACONIC ACIDURIA//3 METHYLGLUTARIC ACID
6 3029 MITOCHONDRIAL DYNAMICS//DRP1//MITOCHONDRIAL FISSION
7 20771 WOLFRAM SYNDROME//WFS1//DIDMOAD
8 4798 COMPLEX I//NADH UBIQUINONE OXIDOREDUCTASE//NIJMEGEN MITOCHONDRIAL DISORDERS
9 8565 OPTIC NEURITIS//MULTIPLE SCLEROSIS//RETINAL NERVE FIBER LAYER
10 24707 AUDITORY NEUROPATHY//AUDITORY NEUROPATHY SPECTRUM DISORDER//AUDITORY DYS SYNCHRONY

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