Class information for:
Level 1: MIBEFRADIL//T TYPE CALCIUM CHANNEL//T TYPE CA2 CHANNEL

Basic class information
Class id #P Avg. number of
references		 Database coverage
of references
9931 1106 44.3 89%


Bar chart of Publication_year

Last years might be incomplete

Hierarchy of classes
The table includes all classes above and classes immediately below the current class.


Cluster id Level Cluster label #P
8 4 CARDIAC & CARDIOVASCULAR SYSTEM//PERIPHERAL VASCULAR DISEASES//CARDIOL 1276458
11 3       ATRIAL FIBRILLATION//CARDIAC & CARDIOVASCULAR SYSTEM//CATHETER ABLATION 130936
2204 2             MIBEFRADIL//T TYPE CALCIUM CHANNEL//CALCIUM CHANNELS 4862
9931 1                   MIBEFRADIL//T TYPE CALCIUM CHANNEL//T TYPE CA2 CHANNEL 1106

Terms with highest relevance score


rank Term termType Chi square Shr. of publ. in
class containing
term		 Class's shr. of
term's tot. occurrences		 #P with
term in
class
1 MIBEFRADIL authKW 2651298 13% 65% 147
2 T TYPE CALCIUM CHANNEL authKW 2331248 14% 56% 151
3 T TYPE CA2 CHANNEL authKW 959334 6% 50% 69
4 T TYPE authKW 575178 4% 53% 39
5 CAV32 authKW 491891 3% 64% 28
6 T TYPE CHANNEL authKW 441700 2% 67% 24
7 T TYPE CALCIUM CHANNEL BLOCKERS authKW 419917 2% 89% 17
8 LOW VOLTAGE ACTIVATED authKW 357780 2% 72% 18
9 EFONIDIPINE authKW 324516 2% 51% 23
10 3 4 DIHYDROQUINAZOLINE authKW 265025 1% 80% 12

Web of Science journal categories


Rank Term Chi square Shr. of publ. in
class containing
term		 Class's shr. of
term's tot. occurrences		 #P with
term in
class
1 Physiology 3006 19% 0% 205
2 Pharmacology & Pharmacy 2047 27% 0% 294
3 Neurosciences 1454 23% 0% 252
4 Cardiac & Cardiovascular System 1108 13% 0% 149
5 Peripheral Vascular Diseases 867 9% 0% 98
6 Chemistry, Medicinal 438 7% 0% 73
7 Cell Biology 235 9% 0% 104
8 Biochemistry & Molecular Biology 76 12% 0% 129
9 Biophysics 59 4% 0% 42
10 Hematology 41 3% 0% 30

Address terms


Rank Term Chi square Shr. of publ. in
class containing
term		 Class's shr. of
term's tot. occurrences		 #P with
term in
class
1 DEP S CIRCADIAN DISORDERS 84539 1% 44% 7
2 S EXCELLENCE ION CHANNEL SCI THER EUT 84539 1% 44% 7
3 CNRSUMR 5203 66250 1% 40% 6
4 INTERDISCIPLINARY PROGRAM BIOTECHNOL 66250 1% 40% 6
5 CNRSUMR 5203IGF PHYSIOL 55214 0% 100% 2
6 DRUG DISCOVERY CHEM BIOL PHARMACOL 55214 0% 100% 2
7 FEDERATIF RECH 3 49691 0% 60% 3
8 QA RA PHARMACOVIGILANCE 40151 0% 36% 4
9 NEURONAL SIGNALING 35492 0% 43% 3
10 U661 35131 2% 6% 20

Journals


Rank Term Chi square Shr. of publ. in
class containing
term		 Class's shr. of
term's tot. occurrences		 #P with
term in
class
1 PFLUGERS ARCHIV-EUROPEAN JOURNAL OF PHYSIOLOGY 10839 5% 1% 57
2 CHANNELS 7578 1% 2% 12
3 CELL CALCIUM 6003 2% 1% 25
4 MOLECULAR PAIN 2588 1% 1% 9
5 JOURNAL OF CARDIOVASCULAR PHARMACOLOGY 2068 3% 0% 29
6 JOURNAL OF PHYSIOLOGY-LONDON 1902 3% 0% 36
7 MOLECULAR PHARMACOLOGY 1730 2% 0% 25
8 JOURNAL OF PHARMACOLOGICAL SCIENCES 1416 1% 0% 11
9 CIRCULATION RESEARCH 1411 2% 0% 23
10 CARDIOVASCULAR DRUGS AND THERAPY 1408 1% 1% 10

Author Key Words


Rank Term Chi square Shr. of publ. in
class containing
term		 Class's shr. of
term's tot. occurrences		 #P with
term in
class		 LCSH search Wikipedia search
1 MIBEFRADIL 2651298 13% 65% 147 Search MIBEFRADIL Search MIBEFRADIL
2 T TYPE CALCIUM CHANNEL 2331248 14% 56% 151 Search T+TYPE+CALCIUM+CHANNEL Search T+TYPE+CALCIUM+CHANNEL
3 T TYPE CA2 CHANNEL 959334 6% 50% 69 Search T+TYPE+CA2+CHANNEL Search T+TYPE+CA2+CHANNEL
4 T TYPE 575178 4% 53% 39 Search T+TYPE Search T+TYPE
5 CAV32 491891 3% 64% 28 Search CAV32 Search CAV32
6 T TYPE CHANNEL 441700 2% 67% 24 Search T+TYPE+CHANNEL Search T+TYPE+CHANNEL
7 T TYPE CALCIUM CHANNEL BLOCKERS 419917 2% 89% 17 Search T+TYPE+CALCIUM+CHANNEL+BLOCKERS Search T+TYPE+CALCIUM+CHANNEL+BLOCKERS
8 LOW VOLTAGE ACTIVATED 357780 2% 72% 18 Search LOW+VOLTAGE+ACTIVATED Search LOW+VOLTAGE+ACTIVATED
9 EFONIDIPINE 324516 2% 51% 23 Search EFONIDIPINE Search EFONIDIPINE
10 3 4 DIHYDROQUINAZOLINE 265025 1% 80% 12 Search 3+4+DIHYDROQUINAZOLINE Search 3+4+DIHYDROQUINAZOLINE

Core articles
The table includes core articles in the class. The following variables is taken into account for the relevance score of an article in a cluster c:
(1) Number of references referring to publications in the class.
(2) Share of total number of active references referring to publications in the class.
(3) Age of the article. New articles get higher score than old articles.
(4) Citation rate, normalized to year.


Rank Reference # ref. in
cl.		 Shr. of ref. in
cl.		 Citations
1 TODOROVIC, SM , JEVTOVIC-TODOROVIC, V , (2011) T-TYPE VOLTAGE-GATED CALCIUM CHANNELS AS TARGETS FOR THE DEVELOPMENT OF NOVEL PAIN THERAPIES.BRITISH JOURNAL OF PHARMACOLOGY. VOL. 163. ISSUE 3. P. 484 -495 81 71% 65
2 PEREZ-REYES, E , (2003) MOLECULAR PHYSIOLOGY OF LOW-VOLTAGE-ACTIVATED T-TYPE CALCIUM CHANNELS.PHYSIOLOGICAL REVIEWS. VOL. 83. ISSUE 1. P. 117-161 130 30% 891
3 BOURINET, E , FRANCOIS, A , LAFFRAY, S , (2016) T-TYPE CALCIUM CHANNELS IN NEUROPATHIC PAIN.PAIN. VOL. 157. ISSUE 2. P. S15 -S22 78 53% 4
4 HANSEN, PBL , (2015) FUNCTIONAL IMPORTANCE OF T-TYPE VOLTAGE-GATED CALCIUM CHANNELS IN THE CARDIOVASCULAR AND RENAL SYSTEM: NEWS FROM THE WORLD OF KNOCKOUT MICE.AMERICAN JOURNAL OF PHYSIOLOGY-REGULATORY INTEGRATIVE AND COMPARATIVE PHYSIOLOGY. VOL. 308. ISSUE 4. P. R227 -R237 71 65% 6
5 HUC, S , MONTEIL, A , BIDAUD, I , BARBARA, G , CHEMIN, J , LORY, P , (2009) REGULATION OF T-TYPE CALCIUM CHANNELS: SIGNALLING PATHWAYS AND FUNCTIONAL IMPLICATIONS.BIOCHIMICA ET BIOPHYSICA ACTA-MOLECULAR CELL RESEARCH. VOL. 1793. ISSUE 6. P. 947 -952 62 84% 26
6 ZHANG, Y , JIANG, XH , SNUTCH, TP , TAO, J , (2013) MODULATION OF LOW-VOLTAGE-ACTIVATED T-TYPE CA2+ CHANNELS.BIOCHIMICA ET BIOPHYSICA ACTA-BIOMEMBRANES. VOL. 1828. ISSUE 7. P. 1550-1559 78 58% 17
7 LI, M , HANSEN, JB , HUANG, L , KEYSER, BM , TAYLOR, JT , (2005) TOWARDS SELECTIVE ANTAGONISTS OF T-TYPE CALCIUM CHANNELS: DESIGN, CHARACTERIZATION AND POTENTIAL APPLICATIONS OF NNC 55-0396.CARDIOVASCULAR DRUG REVIEWS. VOL. 23. ISSUE 2. P. 173-196 82 69% 34
8 GIORDANETTO, F , KNERR, L , WALLBERG, A , (2011) T-TYPE CALCIUM CHANNELS INHIBITORS: A PATENT REVIEW.EXPERT OPINION ON THERAPEUTIC PATENTS. VOL. 21. ISSUE 1. P. 85 -101 45 90% 25
9 MCGIVERN, JG , (2006) PHARMACOLOGY AND DRUG DISCOVERY FOR T-TYPE CALCIUM CHANNELS.CNS & NEUROLOGICAL DISORDERS-DRUG TARGETS. VOL. 5. ISSUE 6. P. 587 -603 108 44% 27
10 ZHANG, Y , WANG, H , QIAN, ZY , FENG, B , ZHAO, XY , JIANG, XH , TAO, J , (2014) LOW-VOLTAGE-ACTIVATED T-TYPE CA2+ CHANNEL INHIBITORS AS NEW TOOLS IN THE TREATMENT OF GLIOBLASTOMA: THE ROLE OF ENDOSTATIN.PFLUGERS ARCHIV-EUROPEAN JOURNAL OF PHYSIOLOGY. VOL. 466. ISSUE 4. P. 811-818 52 72% 3

Classes with closest relation at Level 1


Rank Class id link
1 3095 OMEGA CONOTOXIN GVIA//OMEGA AGATOXIN IVA//OMEGA CONOTOXIN
2 5929 CALCIUM SIGNALS//TIMOTHY SYNDROME//CAV12
3 21976 CILNIDIPINE//BENIDIPINE//AZELNIDIPINE
4 13507 ABSENCE EPILEPSY//WAG RIJ RATS//SPIKE WAVE DISCHARGES
5 10372 SNAIL NEURONS//BURSTS OF POTENTIAL//CENTRAL NEURON
6 3788 THALAMIC RETICULAR NUCLEUS//LATERAL GENICULATE NUCLEUS//THALAMUS
7 4492 DIHYDROPYRIDINE//SR 33557//BAY K 8644
8 35384 CD 832//PRANIDIPINE//KT 362
9 11907 GLOMERULOSA CELLS//ALDOSTERONE SECRETION//ADRENAL GLOMERULOSA
10 21385 AMLODIPINE//NIFEDIPINE GITS//MODERN APPROACH TO THE TREATMENT OF HYPERTENSION MATH TRIAL

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