Class information for:
Level 1: EPIBATIDINE//ABT 594//A 85380

Basic class information
Class id #P Avg. number of
references		 Database coverage
of references
9955 1104 35.2 70%


Bar chart of Publication_year

Last years might be incomplete

Hierarchy of classes
The table includes all classes above and classes immediately below the current class.


Cluster id Level Cluster label #P
11 4 NEUROSCIENCES//CLINICAL NEUROLOGY//NEUROL 1112395
305 3       NICOTINIC ACETYLCHOLINE RECEPTOR//BENZODIAZEPINES//NICOTINIC RECEPTORS 40571
1265 2             NICOTINE//NICOTINIC RECEPTORS//NICOTINIC ACETYLCHOLINE RECEPTOR 8795
9955 1                   EPIBATIDINE//ABT 594//A 85380 1104

Terms with highest relevance score


rank Term termType Chi square Shr. of publ. in
class containing
term		 Class's shr. of
term's tot. occurrences		 #P with
term in
class
1 EPIBATIDINE authKW 939268 8% 39% 88
2 ABT 594 authKW 282849 1% 68% 15
3 A 85380 authKW 239329 1% 58% 15
4 EPIBATIDINE ANALOGUES authKW 224022 1% 90% 9
5 I 123 5 IA 85380 authKW 196672 1% 89% 8
6 7 AZABICYCLO221HEPTANE authKW 169399 1% 88% 7
7 IST NEUROSCI FARMACOL CELLULARE MOL address 160911 1% 73% 8
8 NICOTINIC ACETYLCHOLINE RECEPTOR authKW 153292 9% 6% 100
9 FLUBATINE authKW 138286 0% 100% 5
10 HOMOEPIBATIDINE authKW 138286 0% 100% 5

Web of Science journal categories


Rank Term Chi square Shr. of publ. in
class containing
term		 Class's shr. of
term's tot. occurrences		 #P with
term in
class
1 Chemistry, Organic 9523 42% 0% 464
2 Chemistry, Medicinal 8277 26% 0% 286
3 Pharmacology & Pharmacy 641 16% 0% 179
4 Radiology, Nuclear Medicine & Medical Imaging 312 8% 0% 85
5 Neurosciences 158 10% 0% 105
6 Chemistry, Multidisciplinary 157 11% 0% 118
7 Biochemical Research Methods 43 3% 0% 34
8 Chemistry, Inorganic & Nuclear 19 3% 0% 29
9 Chemistry, Analytical 14 3% 0% 35
10 Psychiatry 8 2% 0% 24

Address terms


Rank Term Chi square Shr. of publ. in
class containing
term		 Class's shr. of
term's tot. occurrences		 #P with
term in
class
1 IST NEUROSCI FARMACOL CELLULARE MOL 160911 1% 73% 8
2 R47W 104113 1% 47% 8
3 NEUROL UROL DIS 93462 1% 26% 13
4 NEUROL UROL DIS D47W 82972 0% 100% 3
5 47W 63213 0% 57% 4
6 PAUL ERRER VILLIGEN 62227 0% 75% 3
7 MULTIMODAL IMAGE PROC 55315 0% 100% 2
8 PHARMACEUT PROD 44619 2% 6% 25
9 4N5 41483 0% 50% 3
10 LRL QC 41483 0% 50% 3

Journals


Rank Term Chi square Shr. of publ. in
class containing
term		 Class's shr. of
term's tot. occurrences		 #P with
term in
class
1 NUCLEAR MEDICINE AND BIOLOGY 8649 3% 1% 34
2 BIOORGANIC & MEDICINAL CHEMISTRY LETTERS 5460 6% 0% 71
3 JOURNAL OF MEDICINAL CHEMISTRY 5209 6% 0% 64
4 SYNAPSE 4821 2% 1% 24
5 JOURNAL OF LABELLED COMPOUNDS & RADIOPHARMACEUTICALS 3549 2% 1% 24
6 TETRAHEDRON LETTERS 2510 8% 0% 83
7 JOURNAL OF ORGANIC CHEMISTRY 1933 6% 0% 61
8 DRUG DEVELOPMENT RESEARCH 1817 1% 0% 14
9 TETRAHEDRON 1587 4% 0% 47
10 HETEROCYCLES 1489 2% 0% 27

Author Key Words


Rank Term Chi square Shr. of publ. in
class containing
term		 Class's shr. of
term's tot. occurrences		 #P with
term in
class		 LCSH search Wikipedia search
1 EPIBATIDINE 939268 8% 39% 88 Search EPIBATIDINE Search EPIBATIDINE
2 ABT 594 282849 1% 68% 15 Search ABT+594 Search ABT+594
3 A 85380 239329 1% 58% 15 Search A+85380 Search A+85380
4 EPIBATIDINE ANALOGUES 224022 1% 90% 9 Search EPIBATIDINE+ANALOGUES Search EPIBATIDINE+ANALOGUES
5 I 123 5 IA 85380 196672 1% 89% 8 Search I+123+5+IA+85380 Search I+123+5+IA+85380
6 7 AZABICYCLO221HEPTANE 169399 1% 88% 7 Search 7+AZABICYCLO221HEPTANE Search 7+AZABICYCLO221HEPTANE
7 NICOTINIC ACETYLCHOLINE RECEPTOR 153292 9% 6% 100 Search NICOTINIC+ACETYLCHOLINE+RECEPTOR Search NICOTINIC+ACETYLCHOLINE+RECEPTOR
8 FLUBATINE 138286 0% 100% 5 Search FLUBATINE Search FLUBATINE
9 HOMOEPIBATIDINE 138286 0% 100% 5 Search HOMOEPIBATIDINE Search HOMOEPIBATIDINE
10 NIFENE 138286 0% 100% 5 Search NIFENE Search NIFENE

Core articles
The table includes core articles in the class. The following variables is taken into account for the relevance score of an article in a cluster c:
(1) Number of references referring to publications in the class.
(2) Share of total number of active references referring to publications in the class.
(3) Age of the article. New articles get higher score than old articles.
(4) Citation rate, normalized to year.


Rank Reference # ref. in
cl.		 Shr. of ref. in
cl.		 Citations
1 BUNNELLE, WH , DART, MJ , SCHRIMPF, MR , (2004) DESIGN OF LIGANDS FOR THE NICOTINIC ACETYLCHOLINE RECEPTORS: THE QUEST FOR SELECTIVITY.CURRENT TOPICS IN MEDICINAL CHEMISTRY. VOL. 4. ISSUE 3. P. 299-334 114 53% 83
2 DALY, JW , (2005) NICOTINIC AGONISTS, ANTAGONISTS, AND MODULATORS FROM NATURAL SOURCES.CELLULAR AND MOLECULAR NEUROBIOLOGY. VOL. 25. ISSUE 3-4. P. 513-552 102 48% 121
3 HORTI, AG , GAO, YJ , KUWABARA, H , DANNALS, RF , (2010) DEVELOPMENT OF RADIOLIGANDS WITH OPTIMIZED IMAGING PROPERTIES FOR QUANTIFICATION OF NICOTINIC ACETYLCHOLINE RECEPTORS BY POSITRON EMISSION TOMOGRAPHY.LIFE SCIENCES. VOL. 86. ISSUE 15-16. P. 575-584 55 86% 23
4 SABRI, O , BECKER, GA , MEYER, PM , HESSE, S , WILKE, S , GRAEF, S , PATT, M , LUTHARDT, J , WAGENKNECHT, G , HOEPPING, A , ET AL (2015) FIRST-IN-HUMAN PET QUANTIFICATION STUDY OF CEREBRAL ALPHA 4 BETA 2*NICOTINIC ACETYLCHOLINE RECEPTORS USING THE NOVEL SPECIFIC RADIOLIGAND (-)-[F-18]FLUBATINE.NEUROIMAGE. VOL. 118. ISSUE . P. 199 -208 37 76% 8
5 ROGER, G , SABA, W , VALETTE, H , HINNEN, F , COULON, C , OTTAVIANI, M , BOTTLAENDER, M , DOLLE, F , (2006) SYNTHESIS AND RADIOSYNTHESIS OF [F-18]FPHEP, A NOVEL ALPHA(4)BETA(2)-SELECTIVE, EPIBATIDINE-BASED ANTAGONIST FOR PET IMAGING OF NICOTINIC ACETYLCHOLINE RECEPTORS.BIOORGANIC & MEDICINAL CHEMISTRY. VOL. 14. ISSUE 11. P. 3848-3858 47 78% 14
6 WEI, ZL , XIAO, YX , GEORGE, C , KELLAR, KJ , KOZIKOWSKI, AP , (2003) FUNCTIONALIZATION OF THE ALICYCLIC SKELETON OF EPIBATIDINE: SYNTHESIS AND NICOTINIC ACETYLCHOLINE RECEPTOR BINDING AFFINITIES OF EPIBATIDINE ANALOGUES.ORGANIC & BIOMOLECULAR CHEMISTRY. VOL. 1. ISSUE 22. P. 3878 -3881 41 93% 12
7 CARROLL, FI , (2004) EPIBATIDINE STRUCTURE-ACTIVITY RELATIONSHIPS.BIOORGANIC & MEDICINAL CHEMISTRY LETTERS. VOL. 14. ISSUE 8. P. 1889-1896 35 97% 55
8 KROW, GR , CHEUNG, OH , HU, ZL , HUANG, QL , HUTCHINSON, J , LIU, NA , NGUYEN, KT , ULRICH, S , YUAN, J , XIAO, YS , ET AL (1999) NITROGEN BRIDGE HOMOEPIBATIDINES. SYN-6-AND SYN-5-(6-CHLORO-3-PYRIDYL)ISOQUINUCLIDINES..TETRAHEDRON. VOL. 55. ISSUE 25. P. 7747-7756 45 92% 22
9 HORTI, AG , KUWABARA, H , HOLT, DP , DANNALS, RF , WONG, DF , (2013) RECENT PET RADIOLIGANDS WITH OPTIMAL BRAIN KINETICS FOR IMAGING NICOTINIC ACETYLCHOLINE RECEPTORS.JOURNAL OF LABELLED COMPOUNDS & RADIOPHARMACEUTICALS. VOL. 56. ISSUE 3-4. P. 159 -166 35 73% 10
10 BREINING, SR , (2004) RECENT DEVELOPMENTS IN THE SYNTHESIS OF NICOTINIC ACETYLCHOLINE RECEPTOR LIGANDS.CURRENT TOPICS IN MEDICINAL CHEMISTRY. VOL. 4. ISSUE 6. P. 609-629 44 73% 35

Classes with closest relation at Level 1


Rank Class id link
1 33697 1 AZATRICYCLOHEPTANES//2 AZABICYCLOHEPTANES//METHANOPYRROLIDINE
2 111 NICOTINE//NICOTINIC RECEPTORS//MECAMYLAMINE
3 12662 CHRNA7//ALPHA 7//ALPHA 7 NICOTINIC RECEPTOR
4 15565 NEOSTIGMINE//CHOLINESTERASE INHIBITORS NEOSTIGMINE//CEREBROSPINAL FLUID COMPONENTS ACETYLCHOLINE NOREPINEPHRINE
5 21950 FP TZTP//IQNP//N C 11METHYL 3 PIPERIDYL BENZILATE
6 18137 ACYLNITROSO//HYDROXYAMINATION//BICYCLIC OLEFIN
7 26526 HEPTACYCLOTETRADECANE//ORBITALS PRECANONICAL//TRANSANNULAR INTERACTION
8 13772 PUMILIOTOXINS//INDOLIZIDINES//QUINOLIZIDINES
9 34592 BALANOL//3 AMINO 4 HYDROXYHEXAHYDROAZEPINE//OPHIOCORDIN
10 754 CYS LOOP RECEPTOR//NICOTINIC ACETYLCHOLINE RECEPTOR//RECEPTOR BIOL

Go to start page