Class information for:
Level 2: JOURNAL OF PHARMACOKINETICS AND BIOPHARMACEUTICS//JOURNAL OF PHARMACOKINETICS AND PHARMACODYNAMICS//NONMEM

Basic class information
Class id #P Avg. number of
references		 Database coverage
of references
1171 9352 28.8 55%


Bar chart of Publication_year

Last years might be incomplete

Hierarchy of classes
The table includes all classes above and classes immediately below the current class.


Cluster id Level Cluster label #P
0 4 BIOCHEMISTRY & MOLECULAR BIOLOGY//CELL BIOLOGY//ONCOLOGY 4064930
230 3       P GLYCOPROTEIN//FMO3//TRIMETHYLAMINURIA 49374
1171 2             JOURNAL OF PHARMACOKINETICS AND BIOPHARMACEUTICS//JOURNAL OF PHARMACOKINETICS AND PHARMACODYNAMICS//NONMEM 9352
5621 1                   JOURNAL OF PHARMACOKINETICS AND PHARMACODYNAMICS//NONMEM//NONLINEAR MIXED EFFECTS MODEL 1596
6428 1                   FAMOTIDINE//RANITIDINE//RANITIDINE HYDROCHLORIDE 1484
10401 1                   MEGX//MONOETHYLGLYCINEXYLIDIDE//LIVER FUNCTION 1067
10654 1                   INTERSPECIES SCALING//VOLUME OF DISTRIBUTION//STEADY STATE VOLUME OF DISTRIBUTION 1044
12791 1                   SECT PHARMACOKINET//BOF 4272//JOURNAL OF PHARMACOKINETICS AND BIOPHARMACEUTICS 880
14290 1                   JOURNAL OF PHARMACOKINETICS AND BIOPHARMACEUTICS//IVIVC//NONLINEAR COMPARTMENTAL MODEL 779
17643 1                   ASAN FDN//AGROPHARMA//DA 125 588
17720 1                   ANTIPYRINE//ZAKLAD CHEM FIZJOL//ZAKLAD CHEM FIZJOLOGICZNEJ 586
21681 1                   NEPHROLOGY CLINICAL PRACTICE GUIDELINES//SERUM MEDIATORS//BILATERAL URETER LIGATED RATS 409
22494 1                   CAS 76 75 5//THIOPENTAL//THIAZOLO3 2 A1 3DIAZEPINE 379
25772 1                   CLOMETHIAZOLE//CHLORMETHIAZOLE//AR R008055 272
29937 1                   CLONIC CONVULSION//1 ANILINO 8 NAPHTHALENESULFONATE ANS//APERIODIC ANALYSIS 177
35824 1                   INO 2628 CZ//EFFICIENCY OF ENTEROHEPATIC CIRCULATION//MNP001 91

Terms with highest relevance score


rank Term termType Chi square Shr. of publ. in
class containing
term		 Class's shr. of
term's tot. occurrences		 #P with term
in class
1 JOURNAL OF PHARMACOKINETICS AND BIOPHARMACEUTICS journal 506842 4% 46% 338
2 JOURNAL OF PHARMACOKINETICS AND PHARMACODYNAMICS journal 425522 3% 47% 277
3 NONMEM authKW 150968 2% 27% 171
4 PHARMACOLOGY & PHARMACY WoSSC 112465 63% 1% 5902
5 BIOPHARMACEUTICS & DRUG DISPOSITION journal 109038 3% 13% 254
6 NONLINEAR MIXED EFFECTS MODEL authKW 85573 1% 35% 76
7 PHARMACOKINETICS authKW 70185 9% 3% 796
8 PL PHARMACOKINET address 66296 1% 29% 69
9 INDIRECT RESPONSE MODELS authKW 64805 0% 83% 24
10 PHARMACOKINET DRUG THER Y address 59484 1% 32% 57

Web of Science journal categories


Rank Term Chi square Shr. of publ. in
class containing
term		 Class's shr. of
term's tot. occurrences		 #P with term
in class
1 Pharmacology & Pharmacy 112465 63% 1% 5902
2 Chemistry, Medicinal 4695 7% 0% 685
3 Gastroenterology & Hepatology 2522 6% 0% 536
4 Toxicology 2316 5% 0% 510
5 Chemistry, Multidisciplinary 1028 10% 0% 919
6 Medical Informatics 1004 1% 0% 133
7 Mathematical & Computational Biology 960 2% 0% 203
8 Anesthesiology 746 2% 0% 190
9 Statistics & Probability 744 3% 0% 254
10 Chemistry, Analytical 507 5% 0% 442

Address terms


Rank Term Chi square Shr. of publ. in
class containing
term		 Class's shr. of
term's tot. occurrences		 #P with
term in
class
1 PL PHARMACOKINET 66296 1% 29% 69
2 PHARMACOKINET DRUG THER Y 59484 1% 32% 57
3 ASAN FDN 56745 0% 87% 20
4 SECT PHARMACOKINET 44133 0% 44% 31
5 AGROPHARMA 40653 0% 69% 18
6 PHARMACEUT BIOSCI 39130 2% 8% 143
7 PHARMACOMETR 31675 0% 28% 35
8 GLOBAL PK PD PHARMACOMETR 28198 0% 79% 11
9 OFF CLIN PHARMACOL BIOPHARMACEUT 26441 0% 34% 24
10 MED DIAGNOST PATHOL 26430 0% 90% 9

Journals


Rank Term Chi square Shr. of publ. in
class containing
term		 Class's shr. of
term's tot. occurrences		 #P with
term in
class
1 JOURNAL OF PHARMACOKINETICS AND BIOPHARMACEUTICS 506842 4% 46% 338
2 JOURNAL OF PHARMACOKINETICS AND PHARMACODYNAMICS 425522 3% 47% 277
3 BIOPHARMACEUTICS & DRUG DISPOSITION 109038 3% 13% 254
4 JOURNAL OF PHARMACEUTICAL SCIENCES 47308 4% 4% 405
5 DRUG METABOLISM AND DISPOSITION 34936 3% 4% 285
6 CLINICAL PHARMACOKINETICS 34809 2% 7% 159
7 AAPS JOURNAL 26438 1% 8% 96
8 PHARMACEUTICAL RESEARCH 25769 3% 3% 253
9 JOURNAL OF CLINICAL PHARMACOLOGY 22333 2% 4% 194
10 CLINICAL PHARMACOLOGY & THERAPEUTICS 22120 2% 3% 200

Author Key Words


Rank Term Chi square Shr. of publ. in
class containing
term		 Class's shr. of
term's tot. occurrences		 #P with
term in
class		 LCSH search Wikipedia search
1 NONMEM 150968 2% 27% 171 Search NONMEM Search NONMEM
2 NONLINEAR MIXED EFFECTS MODEL 85573 1% 35% 76 Search NONLINEAR+MIXED+EFFECTS+MODEL Search NONLINEAR+MIXED+EFFECTS+MODEL
3 PHARMACOKINETICS 70185 9% 3% 796 Search PHARMACOKINETICS Search PHARMACOKINETICS
4 INDIRECT RESPONSE MODELS 64805 0% 83% 24 Search INDIRECT+RESPONSE+MODELS Search INDIRECT+RESPONSE+MODELS
5 PHARMACOMETRICS 57379 0% 40% 44 Search PHARMACOMETRICS Search PHARMACOMETRICS
6 INTERSPECIES SCALING 53864 0% 52% 32 Search INTERSPECIES+SCALING Search INTERSPECIES+SCALING
7 POPULATION PHARMACOKINETICS 52907 1% 12% 132 Search POPULATION+PHARMACOKINETICS Search POPULATION+PHARMACOKINETICS
8 MEGX 46408 0% 68% 21 Search MEGX Search MEGX
9 FAMOTIDINE 46300 1% 19% 76 Search FAMOTIDINE Search FAMOTIDINE
10 MONOETHYLGLYCINEXYLIDIDE 43227 0% 51% 26 Search MONOETHYLGLYCINEXYLIDIDE Search MONOETHYLGLYCINEXYLIDIDE

Core articles
The table includes core articles in the class. The following variables is taken into account for the relevance score of an article in a cluster c:
(1) Number of references referring to publications in the class.
(2) Share of total number of active references referring to publications in the class.
(3) Age of the article. New articles get higher score than old articles.
(4) Citation rate, normalized to year.


Rank Reference # ref. in
cl.		 Shr. of ref. in
cl.		 Citations
1 FAGERHOLM, U , (2007) PREDICTION OF HUMAN PHARMACOKINETICS - EVALUATION OF METHODS FOR PREDICTION OF HEPATIC METABOLIC CLEARANCE.JOURNAL OF PHARMACY AND PHARMACOLOGY. VOL. 59. ISSUE 6. P. 803 -828 156 61% 34
2 LAURITSEN, K , LAURSEN, LS , RASKMADSEN, J , (1990) CLINICAL PHARMACOKINETICS OF DRUGS USED IN THE TREATMENT OF GASTROINTESTINAL-DISEASES .2..CLINICAL PHARMACOKINETICS. VOL. 19. ISSUE 2. P. 94-125 265 53% 30
3 SOMOGYI, A , MUIRHEAD, M , (1987) PHARMACOKINETIC INTERACTIONS OF CIMETIDINE 1987.CLINICAL PHARMACOKINETICS. VOL. 12. ISSUE 5. P. 321-366 137 77% 184
4 LEE, JH , OH, JM , LEE, MG , (2008) EFFECTS OF WATER DEPRIVATION ON DRUG PHARMACOKINETICS: CORRELATION BETWEEN DRUG METABOLISM AND HEPATIC CYP ISOZYMES.ARCHIVES OF PHARMACAL RESEARCH. VOL. 31. ISSUE 8. P. 951-964 78 74% 3
5 JONES, HM , GARDNER, IB , WATSON, KJ , (2009) MODELLING AND PBPK SIMULATION IN DRUG DISCOVERY.AAPS JOURNAL. VOL. 11. ISSUE 1. P. 155-166 51 91% 54
6 FELDMAN, M , BURTON, ME , (1990) DRUG-THERAPY - HISTAMINE2-RECEPTOR ANTAGONISTS - STANDARD THERAPY FOR ACID-PEPTIC DISEASE .1..NEW ENGLAND JOURNAL OF MEDICINE. VOL. 323. ISSUE 24. P. 1672-1680 108 72% 181
7 SUN, DX , YU, LX , YANG, YS , ZHENG, N , ZOU, P , (2012) PREDICTION OF VOLUME OF DISTRIBUTION AT STEADY STATE IN HUMANS: COMPARISON OF DIFFERENT APPROACHES.EXPERT OPINION ON DRUG METABOLISM & TOXICOLOGY. VOL. 8. ISSUE 7. P. 855 -872 53 87% 5
8 ARMUZZI, A , CANDELLI, M , ZOCCO, MA , ANDREOLI, A , DE LORENZO, A , NISTA, EC , MIELE, L , CREMONINI, F , CAZZATO, IA , GRIECO, A , ET AL (2002) REVIEW ARTICLE: BREATH TESTING FOR HUMAN LIVER FUNCTION ASSESSMENT.ALIMENTARY PHARMACOLOGY & THERAPEUTICS. VOL. 16. ISSUE 12. P. 1977-1996 86 63% 73
9 LALANDE, L , CHARPIAT, B , LEBOUCHER, G , TOD, M , (2014) CONSEQUENCES OF RENAL FAILURE ON NON-RENAL CLEARANCE OF DRUGS.CLINICAL PHARMACOKINETICS. VOL. 53. ISSUE 6. P. 521 -532 58 66% 12
10 SHAFI, N , SIDDIQUI, FA , NASEEM, H , SHER, N , ZUBAIR, A , HUSSAIN, A , SIAL, AA , BAIG, MT , (2013) AN OVERVIEW OF ANALYTICAL DETERMINATION OF DILTIAZEM, CIMETIDINE, RANITIDINE, AND FAMOTIDINE BY UV SPECTROPHOTOMETRY AND HPLC TECHNIQUE.JOURNAL OF CHEMISTRY. VOL. . ISSUE . P. - 79 53% 1

Classes with closest relation at Level 2


Rank Class id link
1 1155 PEPT1//ORGANIC CATION TRANSPORTER//OATP1B1
2 1588 CAFFEINE//ENERGY DRINKS//COFFEE
3 415 CYTOCHROME P450//CYP2D6//PREGNANE X RECEPTOR
4 2418 HYDROCHLOROTHIAZIDE//CICLETANINE//TORASEMIDE
5 2479 BREAKTHROUGH PAIN//CANCER PAIN//FENTANYL
6 1613 ACETAMINOPHEN//DRUG INDUCED LIVER INJURY//HEPATOTOXICITY
7 3380 PREOPERATIVE FASTING//CRICOID PRESSURE//COMPLICATIONS ASPIRATION
8 451 JOURNAL OF ANTIMICROBIAL CHEMOTHERAPY//ANTIMICROBIAL AGENTS AND CHEMOTHERAPY//CHEMOTHERAPY-TOKYO
9 2482 HAPTOGLOBIN//ALPHA1 ACID GLYCOPROTEIN//ACUTE PHASE PROTEINS
10 3502 THALLIUM//THALLIUM POISONING//THALLIUM SPECIATION

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