Class information for:
Level 2: NICORANDIL//ISCHEMIC PRECONDITIONING//K ATP CHANNEL

Basic class information
Class id #P Avg. number of
references		 Database coverage
of references
1189 9282 41.3 84%


Bar chart of Publication_year

Last years might be incomplete

Hierarchy of classes
The table includes all classes above and classes immediately below the current class.


Cluster id Level Cluster label #P
8 4 CARDIAC & CARDIOVASCULAR SYSTEM//PERIPHERAL VASCULAR DISEASES//CARDIOL 1276458
11 3       ATRIAL FIBRILLATION//CARDIAC & CARDIOVASCULAR SYSTEM//CATHETER ABLATION 130936
1189 2             NICORANDIL//ISCHEMIC PRECONDITIONING//K ATP CHANNEL 9282
761 1                   ATP SENSITIVE K CHANNEL//K ATP CHANNEL//ATP SENSITIVE POTASSIUM CHANNEL 3098
1374 1                   ISCHEMIC PRECONDITIONING//PRECONDITIONING//ISCHAEMIC PRECONDITIONING 2692
5471 1                   POSTCONDITIONING//REMOTE ISCHEMIC PRECONDITIONING//ISCHEMIC POSTCONDITIONING 1619
11790 1                   INTRACELLULAR ION CHANNELS//DIAZOXIDE//5 HYDROXYDECANOATE 954
15756 1                   NICORANDIL//KRN2391//CAS 65141 46 0 693
27571 1                   PHARMACODYNAM THER EUT//PHARMACODYNAMIE THER EUT//SERV CHIM PHARMACEUT 226

Terms with highest relevance score


rank Term termType Chi square Shr. of publ. in
class containing
term		 Class's shr. of
term's tot. occurrences		 #P with
term in
class
1 NICORANDIL authKW 775442 4% 69% 340
2 ISCHEMIC PRECONDITIONING authKW 760896 6% 44% 523
3 K ATP CHANNEL authKW 724767 5% 48% 464
4 ATP SENSITIVE POTASSIUM CHANNEL authKW 568820 3% 59% 293
5 POSTCONDITIONING authKW 496686 3% 54% 279
6 PRECONDITIONING authKW 461271 8% 20% 703
7 ATP SENSITIVE K CHANNEL authKW 449417 3% 55% 250
8 POTASSIUM CHANNEL OPENERS authKW 406178 2% 66% 188
9 GLIBENCLAMIDE authKW 402233 4% 31% 398
10 DIAZOXIDE authKW 367351 2% 51% 219

Web of Science journal categories


Rank Term Chi square Shr. of publ. in
class containing
term		 Class's shr. of
term's tot. occurrences		 #P with term
in class
1 Cardiac & Cardiovascular System 81366 37% 1% 3436
2 Pharmacology & Pharmacy 16549 26% 0% 2427
3 Peripheral Vascular Diseases 15012 12% 0% 1148
4 Physiology 13536 14% 0% 1288
5 Cell Biology 2295 10% 0% 925
6 Respiratory System 695 3% 0% 266
7 Biophysics 668 4% 0% 390
8 Chemistry, Medicinal 629 3% 0% 299
9 Hematology 543 3% 0% 294
10 Medicine, Research & Experimental 483 4% 0% 363

Address terms


Rank Term Chi square Shr. of publ. in
class containing
term		 Class's shr. of
term's tot. occurrences		 #P with
term in
class
1 INTRACELLULAR ION CHANNELS 113033 1% 72% 48
2 HATTER CARDIOVASC 97073 1% 33% 90
3 HATTER CARDIOVASC STUDIES 48935 0% 41% 36
4 PHARMACODYNAM THER EUT 45240 0% 81% 17
5 HATTER 41592 0% 38% 33
6 MOL CARDIOBIOL 33845 0% 25% 41
7 PHYSIOL LYON NORD 27135 0% 52% 16
8 PHARMACODYNAMIE THER EUT 26839 0% 58% 14
9 HEART FDN 24285 0% 19% 38
10 CHIM PHARMACEUT 19784 0% 22% 28

Journals


Rank Term Chi square Shr. of publ. in
class containing
term		 Class's shr. of
term's tot. occurrences		 #P with
term in
class
1 BASIC RESEARCH IN CARDIOLOGY 62417 2% 8% 232
2 CARDIOVASCULAR RESEARCH 52028 4% 5% 353
3 AMERICAN JOURNAL OF PHYSIOLOGY-HEART AND CIRCULATORY PHYSIOLOGY 50351 5% 4% 438
4 JOURNAL OF MOLECULAR AND CELLULAR CARDIOLOGY 48643 3% 5% 311
5 JOURNAL OF CARDIOVASCULAR PHARMACOLOGY 26507 3% 3% 300
6 CARDIOVASCULAR DRUGS AND THERAPY 17841 1% 5% 103
7 BRITISH JOURNAL OF PHARMACOLOGY 16825 3% 2% 305
8 CIRCULATION RESEARCH 14882 2% 2% 216
9 JOURNAL OF CARDIOVASCULAR PHARMACOLOGY AND THERAPEUTICS 10781 0% 8% 44
10 EUROPEAN JOURNAL OF PHARMACOLOGY 8308 3% 1% 273

Author Key Words


Rank Term Chi square Shr. of publ. in
class containing
term		 Class's shr. of
term's tot. occurrences		 #P with
term in
class		 LCSH search Wikipedia search
1 NICORANDIL 775442 4% 69% 340 Search NICORANDIL Search NICORANDIL
2 ISCHEMIC PRECONDITIONING 760896 6% 44% 523 Search ISCHEMIC+PRECONDITIONING Search ISCHEMIC+PRECONDITIONING
3 K ATP CHANNEL 724767 5% 48% 464 Search K+ATP+CHANNEL Search K+ATP+CHANNEL
4 ATP SENSITIVE POTASSIUM CHANNEL 568820 3% 59% 293 Search ATP+SENSITIVE+POTASSIUM+CHANNEL Search ATP+SENSITIVE+POTASSIUM+CHANNEL
5 POSTCONDITIONING 496686 3% 54% 279 Search POSTCONDITIONING Search POSTCONDITIONING
6 PRECONDITIONING 461271 8% 20% 703 Search PRECONDITIONING Search PRECONDITIONING
7 ATP SENSITIVE K CHANNEL 449417 3% 55% 250 Search ATP+SENSITIVE+K+CHANNEL Search ATP+SENSITIVE+K+CHANNEL
8 POTASSIUM CHANNEL OPENERS 406178 2% 66% 188 Search POTASSIUM+CHANNEL+OPENERS Search POTASSIUM+CHANNEL+OPENERS
9 GLIBENCLAMIDE 402233 4% 31% 398 Search GLIBENCLAMIDE Search GLIBENCLAMIDE
10 DIAZOXIDE 367351 2% 51% 219 Search DIAZOXIDE Search DIAZOXIDE

Core articles
The table includes core articles in the class. The following variables is taken into account for the relevance score of an article in a cluster c:
(1) Number of references referring to publications in the class.
(2) Share of total number of active references referring to publications in the class.
(3) Age of the article. New articles get higher score than old articles.
(4) Citation rate, normalized to year.


Rank Reference # ref. in
cl.		 Shr. of ref. in
cl.		 Citations
1 FOSTER, MN , COETZEE, WA , (2016) K-ATP CHANNELS IN THE CARDIOVASCULAR SYSTEM.PHYSIOLOGICAL REVIEWS. VOL. 96. ISSUE 1. P. 177 -252 604 69% 4
2 HEUSCH, G , (2015) MOLECULAR BASIS OF CARDIOPROTECTION SIGNAL TRANSDUCTION IN ISCHEMIC PRE-, POST-, AND REMOTE CONDITIONING.CIRCULATION RESEARCH. VOL. 116. ISSUE 4. P. 674 -699 292 62% 98
3 FLAGG, TP , ENKVETCHAKUL, D , KOSTER, JC , NICHOLS, CG , (2010) MUSCLE K-ATP CHANNELS: RECENT INSIGHTS TO ENERGY SENSING AND MYOPROTECTION.PHYSIOLOGICAL REVIEWS. VOL. 90. ISSUE 3. P. 799 -829 341 77% 100
4 YELLON, DM , DOWNEY, JM , (2003) PRECONDITIONING THE MYOCARDIUM: FROM CELLULAR PHYSIOLOGY TO CLINICAL CARDIOLOGY.PHYSIOLOGICAL REVIEWS. VOL. 83. ISSUE 4. P. 1113 -1151 285 75% 602
5 FERDINANDY, P , HAUSENLOY, DJ , HEUSCH, G , BAXTER, GF , SCHULZ, R , (2014) INTERACTION OF RISK FACTORS, COMORBIDITIES, AND COMEDICATIONS WITH ISCHEMIA/REPERFUSION INJURY AND CARDIOPROTECTION BY PRECONDITIONING, POSTCONDITIONING, AND REMOTE CONDITIONING.PHARMACOLOGICAL REVIEWS. VOL. 66. ISSUE 4. P. 1142 -1174 243 64% 84
6 HEUSCH, G , BOTKER, HE , PRZYKLENK, K , REDINGTON, A , YELLON, D , (2015) REMOTE ISCHEMIC CONDITIONING.JOURNAL OF THE AMERICAN COLLEGE OF CARDIOLOGY. VOL. 65. ISSUE 2. P. 177 -195 153 81% 67
7 QUAYLE, JM , NELSON, MT , STANDEN, NB , (1997) ATP-SENSITIVE AND INWARDLY RECTIFYING POTASSIUM CHANNELS IN SMOOTH MUSCLE.PHYSIOLOGICAL REVIEWS. VOL. 77. ISSUE 4. P. 1165-1232 350 60% 497
8 HAUSENLOY, DJ , YELLON, DM , (2016) ISCHAEMIC CONDITIONING AND REPERFUSION INJURY.NATURE REVIEWS CARDIOLOGY. VOL. 13. ISSUE 4. P. 193 -209 133 86% 10
9 HAUSENLOY, DJ , (2013) CARDIOPROTECTION TECHNIQUES: PRECONDITIONING, POSTCONDITIONING AND REMOTE CON-DITIONING (BASIC SCIENCE).CURRENT PHARMACEUTICAL DESIGN. VOL. 19. ISSUE 25. P. 4544 -4563 198 85% 29
10 HEUSCH, G , RASSAF, T , (2016) TIME TO GIVE UP ON CARDIOPROTECTION?: A CRITICAL APPRAISAL OF CLINICAL STUDIES ON ISCHEMIC PRE-, POST-, AND REMOTE CONDITIONING*.CIRCULATION RESEARCH. VOL. 119. ISSUE 5. P. 676 -695 188 85% 2

Classes with closest relation at Level 2


Rank Class id link
1 377 JOURNAL OF MOLECULAR AND CELLULAR CARDIOLOGY//PHOSPHOLAMBAN//CARDIAC & CARDIOVASCULAR SYSTEM
2 2578 MODY//CONGENITAL HYPERINSULINISM//NEONATAL DIABETES
3 938 CARDIAC HYPERTROPHY//HYPERTROPHY//CARDIOTROPHIN 1
4 691 POTASSIUM CHANNELS//BK CHANNEL//RETIGABINE
5 1896 METFORMIN//ACARBOSE//REPAGLINIDE
6 1752 LESCH NYHAN SYNDROME//AMP DEAMINASE//LESCH NYHAN DISEASE
7 381 MITOCHONDRIA//MELAS//MITOCHONDRIAL DISEASE
8 2821 NITRATE TOLERANCE//NITROGLYCERIN//ORGANIC NITRATES
9 1243 NAUNYN-SCHMIEDEBERGS ARCHIVES OF PHARMACOLOGY//JOURNAL OF AUTONOMIC PHARMACOLOGY//BLOOD VESSELS
10 1804 ARTERIOGENESIS//COLLATERAL CIRCULATION//TRANSMYOCARDIAL LASER REVASCULARIZATION

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