Class information for:
Level 2: CD44//HYALURONAN//HYALURONIC ACID

Basic class information
Class id #P Avg. number of
references		 Database coverage
of references
1856 6076 40.4 78%


Bar chart of Publication_year

Last years might be incomplete

Hierarchy of classes
The table includes all classes above and classes immediately below the current class.


Cluster id Level Cluster label #P
0 4 BIOCHEMISTRY & MOLECULAR BIOLOGY//CELL BIOLOGY//ONCOLOGY 4064930
250 3       OSTEOARTHRITIS//OSTEOARTHRITIS AND CARTILAGE//CHONDROCYTE 46264
1856 2             CD44//HYALURONAN//HYALURONIC ACID 6076
1180 1                   HYALURONAN//HYALURONAN SYNTHASE//HYALURONIDASE 2800
2672 1                   CD44//CD44V6//CD44S 2177
13107 1                   STREPTOCOCCUS ZOOEPIDEMICUS//ROTATIONAL VISCOMETRY//HYALURONIC ACID 860
33379 1                   ALDEHYDODEXTRAN//ALGEBRAIC PROGRESSION//CARDIOL KAUNAS 125
34267 1                   HYALURONATE LYASE//HYALURONAN LYASE//ACTION PATHWAY 114

Terms with highest relevance score


rank Term termType Chi square Shr. of publ. in
class containing
term		 Class's shr. of
term's tot. occurrences		 #P with
term in
class
1 CD44 authKW 2153826 16% 45% 950
2 HYALURONAN authKW 1988095 16% 41% 963
3 HYALURONIC ACID authKW 491207 10% 17% 591
4 HYALURONIDASE authKW 476026 4% 36% 264
5 HYALURONAN SYNTHASE authKW 410776 2% 76% 107
6 CD44V6 authKW 408738 2% 65% 125
7 RHAMM authKW 307681 1% 88% 70
8 CD44S authKW 147606 1% 64% 46
9 CD44 ISOFORMS authKW 137003 0% 91% 30
10 CD44 VARIANTS authKW 131969 1% 77% 34

Web of Science journal categories


Rank Term Chi square Shr. of publ. in
class containing
term		 Class's shr. of
term's tot. occurrences		 #P with term
in class
1 Oncology 6463 18% 0% 1121
2 Biochemistry & Molecular Biology 3572 24% 0% 1429
3 Cell Biology 3400 14% 0% 839
4 Pathology 1846 6% 0% 339
5 Immunology 1023 8% 0% 488
6 Dermatology 627 3% 0% 180
7 Medicine, Research & Experimental 560 5% 0% 290
8 Biophysics 548 5% 0% 277
9 Polymer Science 451 4% 0% 272
10 Rheumatology 434 2% 0% 112

Address terms


Rank Term Chi square Shr. of publ. in
class containing
term		 Class's shr. of
term's tot. occurrences		 #P with
term in
class
1 TUMOR PROG S IMMUNE DEF 47133 0% 36% 26
2 ENDOCRINE UNIT 111N 37858 0% 54% 14
3 MATRIX BIOL PROGRAM 30754 0% 44% 14
4 HYALURONAN 29224 0% 73% 8
5 POLICLIN UNIVSECT MED CHEM 25118 0% 100% 5
6 OKLAHOMA MED GLYCOBIOL 24266 0% 17% 28
7 MOL SCI MED 24211 1% 15% 32
8 DIPARTIMENTO SCI CHIRURG MORFOL 21407 0% 47% 9
9 MOL BIOL CLIN 16074 0% 80% 4
10 DIFEMA MERCI 15071 0% 100% 3

Journals


Rank Term Chi square Shr. of publ. in
class containing
term		 Class's shr. of
term's tot. occurrences		 #P with
term in
class
1 MATRIX BIOLOGY 7832 1% 3% 46
2 GLYCOBIOLOGY 5065 1% 2% 54
3 CARBOHYDRATE POLYMERS 3702 2% 1% 93
4 JOURNAL OF BIOLOGICAL CHEMISTRY 2648 5% 0% 306
5 CELL ADHESION AND COMMUNICATION 2206 0% 4% 11
6 MATRIX 1974 0% 4% 10
7 JOURNAL OF CLINICAL PATHOLOGY-CLINICAL MOLECULAR PATHOLOGY EDITION 1866 0% 5% 7
8 CLINICAL & EXPERIMENTAL METASTASIS 1654 0% 1% 26
9 ADVANCES IN CANCER RESEARCH 1643 0% 2% 15
10 INTERNATIONAL JOURNAL OF CANCER 1535 1% 0% 82

Author Key Words


Rank Term Chi square Shr. of publ. in
class containing
term		 Class's shr. of
term's tot. occurrences		 #P with
term in
class		 LCSH search Wikipedia search
1 CD44 2153826 16% 45% 950 Search CD44 Search CD44
2 HYALURONAN 1988095 16% 41% 963 Search HYALURONAN Search HYALURONAN
3 HYALURONIC ACID 491207 10% 17% 591 Search HYALURONIC+ACID Search HYALURONIC+ACID
4 HYALURONIDASE 476026 4% 36% 264 Search HYALURONIDASE Search HYALURONIDASE
5 HYALURONAN SYNTHASE 410776 2% 76% 107 Search HYALURONAN+SYNTHASE Search HYALURONAN+SYNTHASE
6 CD44V6 408738 2% 65% 125 Search CD44V6 Search CD44V6
7 RHAMM 307681 1% 88% 70 Search RHAMM Search RHAMM
8 CD44S 147606 1% 64% 46 Search CD44S Search CD44S
9 CD44 ISOFORMS 137003 0% 91% 30 Search CD44+ISOFORMS Search CD44+ISOFORMS
10 CD44 VARIANTS 131969 1% 77% 34 Search CD44+VARIANTS Search CD44+VARIANTS

Core articles
The table includes core articles in the class. The following variables is taken into account for the relevance score of an article in a cluster c:
(1) Number of references referring to publications in the class.
(2) Share of total number of active references referring to publications in the class.
(3) Age of the article. New articles get higher score than old articles.
(4) Citation rate, normalized to year.


Rank Reference # ref. in
cl.		 Shr. of ref. in
cl.		 Citations
1 JIANG, DH , LIANG, JR , NOBLE, PW , (2011) HYALURONAN AS AN IMMUNE REGULATOR IN HUMAN DISEASES.PHYSIOLOGICAL REVIEWS. VOL. 91. ISSUE 1. P. 221 -264 292 58% 266
2 MISRA, S , HASCALL, VC , MARKWALD, RR , GHATAK, S , (2015) INTERACTIONS BETWEEN HYALURONAN AND ITS RECEPTORS (CD44, RHAMM) REGULATE THE ACTIVITIES OF INFLAMMATION AND CANCER.FRONTIERS IN IMMUNOLOGY. VOL. 6. ISSUE . P. - 265 70% 30
3 MONSLOW, J , GOVINDARAJU, P , PURE, E , (2015) HYALURONAN - A FUNCTIONAL AND STRUCTURAL SWEET SPOT IN THE TISSUE MICROENVIRONMENT.FRONTIERS IN IMMUNOLOGY. VOL. 6. ISSUE . P. - 211 78% 11
4 LIANG, JR , JIANG, DH , NOBLE, PW , (2016) HYALURONAN AS A THERAPEUTIC TARGET IN HUMAN DISEASES.ADVANCED DRUG DELIVERY REVIEWS. VOL. 97. ISSUE . P. 186 -203 204 65% 6
5 NAOR, D , SIONOV, RV , ISHSHALOM, D , (1997) CD44: STRUCTURE, FUNCTION, AND ASSOCIATION WITH THE MALIGNANT PROCESS.ADVANCES IN CANCER RESEARCH, VOL 71. VOL. 71. ISSUE . P. 241 -319 263 72% 479
6 NAOR, D , NEDVETZKI, S , GOLAN, I , MELNIK, L , FAITELSON, Y , (2002) CD44 IN CANCER.CRITICAL REVIEWS IN CLINICAL LABORATORY SCIENCES. VOL. 39. ISSUE 6. P. 527-579 223 83% 273
7 SCHMAUS, A , BAUER, J , SLEEMAN, JP , (2014) SUGARS IN THE MICROENVIRONMENT: THE STICKY PROBLEM OF HA TURNOVER IN TUMORS.CANCER AND METASTASIS REVIEWS. VOL. 33. ISSUE 4. P. 1059 -1079 199 85% 5
8 STERN, R , ASARI, AA , SUGAHARA, KN , (2006) HYALURONAN FRAGMENTS: AN INFORMATION-RICH SYSTEM.EUROPEAN JOURNAL OF CELL BIOLOGY. VOL. 85. ISSUE 8. P. 699 -715 126 82% 442
9 TOOLE, BP , (2004) HYALURONAN: FROM EXTRACELLULAR GLUE TO PERICELLULAR CUE.NATURE REVIEWS CANCER. VOL. 4. ISSUE 7. P. 528-539 122 71% 883
10 MARHABA, R , ZOLLER, M , (2004) CD44 IN CANCER PROGRESSION: ADHESION, MIGRATION AND GROWTH REGULATION.JOURNAL OF MOLECULAR HISTOLOGY. VOL. 35. ISSUE 3. P. 211-231 189 60% 240

Classes with closest relation at Level 2


Rank Class id link
1 794 PROTEOGLYCAN//HEPARANASE//HEPARAN SULFATE
2 3227 OSTEOPONTIN//OSTEOPONTIN OPN//OPN
3 3602 EZRIN//MOESIN//RADIXIN
4 1853 CANCER STEM CELLS//CD133//SIDE POPULATION
5 72 OSTEOARTHRITIS//OSTEOARTHRITIS AND CARTILAGE//CHONDROCYTE
6 821 SELECTINS//ADHESION MOLECULES//E SELECTIN
7 4114 PYRIMIDINOPHANES//PARKIA SPECIOSA//TEMUAN
8 1922 RHEUMATOID ARTHRITIS//RADIATION SYNOVECTOMY//RHEUMATOLOGY
9 2107 LYMPHANGIOGENESIS//VEGF C//PODOPLANIN
10 2123 GLYCOCALYX//MICROVASCULAR RESEARCH//ENDOTHELIAL GLYCOCALYX

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