Class information for:
Level 2: HIRSCHSPRUNGS DISEASE//HIRSCHSPRUNG DISEASE//AGANGLIONOSIS

Basic class information
Class id #P Avg. number of
references		 Database coverage
of references
2417 4148 35.1 74%


Bar chart of Publication_year

Last years might be incomplete

Hierarchy of classes
The table includes all classes above and classes immediately below the current class.


Cluster id Level Cluster label #P
6 4 GASTROENTEROLOGY & HEPATOLOGY//ONCOLOGY//SURGERY 1371034
337 3       IRRITABLE BOWEL SYNDROME//CONSTIPATION//ENTERIC NERVOUS SYSTEM 37464
2417 2             HIRSCHSPRUNGS DISEASE//HIRSCHSPRUNG DISEASE//AGANGLIONOSIS 4148
5796 1                   HIRSCHSPRUNGS DISEASE//INTESTINAL NEURONAL DYSPLASIA//HIRSCHSPRUNG DISEASE 1573
11097 1                   ENTERIC NERVOUS SYSTEM//HIRSCHSPRUNGS DISEASE//HIRSCHSPRUNG DISEASE 1007
13237 1                   ANIRIDIA//PAX6//PAX6 GENE 852
21001 1                   WAARDENBURG SYNDROME//PAX3//KLEIN WAARDENBURG SYNDROME 437
25537 1                   PAX8//PAX5//PAX2 279

Terms with highest relevance score


rank Term termType Chi square Shr. of publ. in
class containing
term		 Class's shr. of
term's tot. occurrences		 #P with
term in
class
1 HIRSCHSPRUNGS DISEASE authKW 3740861 17% 73% 692
2 HIRSCHSPRUNG DISEASE authKW 1271623 7% 62% 277
3 AGANGLIONOSIS authKW 690661 3% 78% 121
4 INTESTINAL NEURONAL DYSPLASIA authKW 682484 2% 92% 101
5 WAARDENBURG SYNDROME authKW 539161 2% 72% 102
6 ANIRIDIA authKW 415049 2% 59% 95
7 PAX6 authKW 413500 4% 32% 176
8 ENTERIC NERVOUS SYSTEM authKW 370452 7% 16% 308
9 HYPOGANGLIONOSIS authKW 325140 1% 82% 54
10 HIRSCHSPRUNG authKW 296996 1% 78% 52

Web of Science journal categories


Rank Term Chi square Shr. of publ. in
class containing
term		 Class's shr. of
term's tot. occurrences		 #P with term
in class
1 Pediatrics 29274 29% 0% 1213
2 Surgery 10856 28% 0% 1180
3 Developmental Biology 8784 10% 0% 396
4 Genetics & Heredity 4286 14% 0% 600
5 Gastroenterology & Hepatology 2126 8% 0% 314
6 Pathology 2108 7% 0% 290
7 Ophthalmology 1339 5% 0% 226
8 Anatomy & Morphology 1007 2% 0% 96
9 Cell Biology 551 8% 0% 329
10 Neurosciences 243 7% 0% 297

Address terms


Rank Term Chi square Shr. of publ. in
class containing
term		 Class's shr. of
term's tot. occurrences		 #P with
term in
class
1 PEDIAT SURG 90215 12% 3% 487
2 GENET REPROD FETAL MED 55650 0% 69% 11
3 NEURONAL DIFFERENTIAT REGENERAT 42874 0% 45% 13
4 PAEDIAT SURG 33390 3% 3% 136
5 PEDIAT NEUROGASTROENTEROL PROGRAM 29438 0% 100% 4
6 UNIDAD GEST CLIN CIRUGIA INFANTIL 29434 0% 67% 6
7 CONWAY BIOMED 26271 0% 36% 10
8 PEDIAT CONGENITAL MALFORMAT 23549 0% 80% 4
9 UNIDAD GEST CLIN GENET REPROD MED FETAL 23541 0% 40% 8
10 NEURAL DIFFERENTIAT REGENERAT 22995 0% 63% 5

Journals


Rank Term Chi square Shr. of publ. in
class containing
term		 Class's shr. of
term's tot. occurrences		 #P with
term in
class
1 JOURNAL OF PEDIATRIC SURGERY 132871 12% 4% 505
2 PEDIATRIC SURGERY INTERNATIONAL 83254 6% 5% 240
3 EUROPEAN JOURNAL OF PEDIATRIC SURGERY 32215 3% 4% 107
4 ZEITSCHRIFT FUR KINDERCHIRURGIE-SURGERY IN INFANCY AND CHILDHOOD 7989 1% 3% 35
5 NEUROGASTROENTEROLOGY AND MOTILITY 6769 1% 2% 49
6 SEMINARS IN PEDIATRIC SURGERY 6623 0% 5% 19
7 DEVELOPMENTAL BIOLOGY 4999 2% 1% 98
8 MOLECULAR VISION 4457 1% 1% 45
9 JOURNAL OF PEDIATRIC GASTROENTEROLOGY AND NUTRITION 3517 1% 1% 59
10 DEVELOPMENT 2732 2% 1% 70

Author Key Words


Rank Term Chi square Shr. of publ. in
class containing
term		 Class's shr. of
term's tot. occurrences		 #P with
term in
class		 LCSH search Wikipedia search
1 HIRSCHSPRUNGS DISEASE 3740861 17% 73% 692 Search HIRSCHSPRUNGS+DISEASE Search HIRSCHSPRUNGS+DISEASE
2 HIRSCHSPRUNG DISEASE 1271623 7% 62% 277 Search HIRSCHSPRUNG+DISEASE Search HIRSCHSPRUNG+DISEASE
3 AGANGLIONOSIS 690661 3% 78% 121 Search AGANGLIONOSIS Search AGANGLIONOSIS
4 INTESTINAL NEURONAL DYSPLASIA 682484 2% 92% 101 Search INTESTINAL+NEURONAL+DYSPLASIA Search INTESTINAL+NEURONAL+DYSPLASIA
5 WAARDENBURG SYNDROME 539161 2% 72% 102 Search WAARDENBURG+SYNDROME Search WAARDENBURG+SYNDROME
6 ANIRIDIA 415049 2% 59% 95 Search ANIRIDIA Search ANIRIDIA
7 PAX6 413500 4% 32% 176 Search PAX6 Search PAX6
8 ENTERIC NERVOUS SYSTEM 370452 7% 16% 308 Search ENTERIC+NERVOUS+SYSTEM Search ENTERIC+NERVOUS+SYSTEM
9 HYPOGANGLIONOSIS 325140 1% 82% 54 Search HYPOGANGLIONOSIS Search HYPOGANGLIONOSIS
10 HIRSCHSPRUNG 296996 1% 78% 52 Search HIRSCHSPRUNG Search HIRSCHSPRUNG

Core articles
The table includes core articles in the class. The following variables is taken into account for the relevance score of an article in a cluster c:
(1) Number of references referring to publications in the class.
(2) Share of total number of active references referring to publications in the class.
(3) Age of the article. New articles get higher score than old articles.
(4) Citation rate, normalized to year.


Rank Reference # ref. in
cl.		 Shr. of ref. in
cl.		 Citations
1 LAKE, JI , HEUCKEROTH, RO , (2013) ENTERIC NERVOUS SYSTEM DEVELOPMENT: MIGRATION, DIFFERENTIATION, AND DISEASE.AMERICAN JOURNAL OF PHYSIOLOGY-GASTROINTESTINAL AND LIVER PHYSIOLOGY. VOL. 305. ISSUE 1. P. G1-G24 154 70% 66
2 OBERMAYR, F , HOTTA, R , ENOMOTO, H , YOUNG, HM , (2013) DEVELOPMENT AND DEVELOPMENTAL DISORDERS OF THE ENTERIC NERVOUS SYSTEM.NATURE REVIEWS GASTROENTEROLOGY & HEPATOLOGY. VOL. 10. ISSUE 1. P. 43 -57 150 72% 50
3 PINGAULT, V , ENTE, D , DASTOT-LE MOAL, F , GOOSSENS, M , MARLIN, S , BONDURAND, N , (2010) REVIEW AND UPDATE OF MUTATIONS CAUSING WAARDENBURG SYNDROME.HUMAN MUTATION. VOL. 31. ISSUE 4. P. 391 -406 123 67% 143
4 BONDURAND, N , SOUTHARD-SMITH, EM , (2016) MOUSE MODELS OF HIRSCHSPRUNG DISEASE AND OTHER DEVELOPMENTAL DISORDERS OF THE ENTERIC NERVOUS SYSTEM: OLD AND NEW PLAYERS.DEVELOPMENTAL BIOLOGY. VOL. 417. ISSUE 2. P. 139 -157 127 69% 1
5 TJADEN, NEB , TRAINOR, PA , (2013) THE DEVELOPMENTAL ETIOLOGY AND PATHOGENESIS OF HIRSCHSPRUNG DISEASE.TRANSLATIONAL RESEARCH. VOL. 162. ISSUE 1. P. 1-15 109 71% 18
6 SASSELLI, V , PACHNIS, V , BURNS, AJ , (2012) THE ENTERIC NERVOUS SYSTEM.DEVELOPMENTAL BIOLOGY. VOL. 366. ISSUE 1. P. 64 -73 94 73% 63
7 BURNS, AJ , GOLDSTEIN, AM , NEWGREEN, DF , STAMP, L , SCHAFER, KH , METZGER, M , HOTTA, R , YOUNG, HM , ANDREWS, PW , THAPAR, N , ET AL (2016) WHITE PAPER ON GUIDELINES CONCERNING ENTERIC NERVOUS SYSTEM STEM CELL THERAPY FOR ENTERIC NEUROPATHIES.DEVELOPMENTAL BIOLOGY. VOL. 417. ISSUE 2. P. 229 -251 115 53% 4
8 SONG, J , FENG, Y , ACKE, FR , COUCKE, P , VLEMINCKX, K , DHOOGE, IJ , (2016) HEARING LOSS IN WAARDENBURG SYNDROME: A SYSTEMATIC REVIEW.CLINICAL GENETICS. VOL. 89. ISSUE 4. P. 416 -425 80 81% 2
9 HEANUE, TA , PACHNIS, V , (2007) ENTERIC NERVOUS SYSTEM DEVELOPMENT AND HIRSCHSPRUNG'S DISEASE: ADVANCES IN GENETIC AND STEM CELL STUDIES.NATURE REVIEWS NEUROSCIENCE. VOL. 8. ISSUE 6. P. 466-479 91 71% 224
10 GOLDSTEIN, AM , HOFSTRA, RMW , BURNS, AJ , (2013) BUILDING A BRAIN IN THE GUT: DEVELOPMENT OF THE ENTERIC NERVOUS SYSTEM.CLINICAL GENETICS. VOL. 83. ISSUE 4. P. 307-316 77 74% 40

Classes with closest relation at Level 2


Rank Class id link
1 349 DEVELOPMENTAL BIOLOGY//DEVELOPMENT//NEURAL CREST
2 111 IRRITABLE BOWEL SYNDROME//NEUROGASTROENTEROLOGY AND MOTILITY//FUNCTIONAL DYSPEPSIA
3 2382 WILMS TUMOR//WT1//NEPHROBLASTOMA
4 1379 FECAL INCONTINENCE//RECTAL PROLAPSE//HEMORRHOIDS
5 2848 CHARGE SYNDROME//CHOANAL ATRESIA//AICARDI SYNDROME
6 1583 TYROSINASE//MELANOGENESIS//PIGMENT CELL RESEARCH
7 2085 MECKELS DIVERTICULUM//MALROTATION//HYPERTROPHIC PYLORIC STENOSIS
8 1384 GDNF//GLIAL CELL LINE DERIVED NEUROTROPHIC FACTOR//NEURAL TRANSPLANTATION
9 2641 EPITHELIAL MESENCHYMAL TRANSITION//EMT//SNAIL
10 3833 CITED2//BRANCHIO OCULO FACIAL SYNDROME//AP 2 ALPHA

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