Class information for:
Level 2: CADASIL//NOTCH3//NOTCH

Basic class information
Class id #P Avg. number of
references		 Database coverage
of references
2542 3755 47.3 93%


Bar chart of Publication_year

Last years might be incomplete

Hierarchy of classes
The table includes all classes above and classes immediately below the current class.


Cluster id Level Cluster label #P
0 4 BIOCHEMISTRY & MOLECULAR BIOLOGY//CELL BIOLOGY//ONCOLOGY 4064930
27 3       DEVELOPMENTAL BIOLOGY//DEVELOPMENT//AGR2 109777
2542 2             CADASIL//NOTCH3//NOTCH 3755
3243 1                   NOTCH1//NOTCH//GAMMA SECRETASE INHIBITOR 2030
11708 1                   DLL4//VASC PATTERNING//DELTA LIKE LIGAND 4 960
14523 1                   CADASIL//NOTCH3//NOTCH3 GENE 765

Terms with highest relevance score


rank Term termType Chi square Shr. of publ. in
class containing
term		 Class's shr. of
term's tot. occurrences		 #P with
term in
class
1 CADASIL authKW 2755514 11% 85% 397
2 NOTCH3 authKW 1214880 5% 80% 187
3 NOTCH authKW 770487 14% 18% 539
4 NOTCH1 authKW 738425 7% 37% 246
5 NOTCH SIGNALING authKW 352355 5% 24% 180
6 GAMMA SECRETASE INHIBITOR authKW 308523 2% 43% 88
7 NOTCH3 GENE authKW 300812 1% 100% 37
8 DLL4 authKW 256735 1% 69% 46
9 JAGGED1 authKW 202567 2% 36% 69
10 NOTCH SIGNALING PATHWAY authKW 131360 1% 39% 41

Web of Science journal categories


Rank Term Chi square Shr. of publ. in
class containing
term		 Class's shr. of
term's tot. occurrences		 #P with
term in
class
1 Oncology 7910 25% 0% 938
2 Cell Biology 5321 21% 0% 773
3 Developmental Biology 5098 8% 0% 290
4 Hematology 3296 10% 0% 365
5 Clinical Neurology 2990 14% 0% 509
6 Peripheral Vascular Diseases 1481 7% 0% 245
7 Pathology 1073 5% 0% 204
8 Medicine, Research & Experimental 761 6% 0% 242
9 Immunology 753 9% 0% 322
10 Cell & Tissue Engineering 542 1% 0% 45

Address terms


Rank Term Chi square Shr. of publ. in
class containing
term		 Class's shr. of
term's tot. occurrences		 #P with
term in
class
1 VASC PATTERNING 126921 1% 71% 22
2 U740 90316 1% 56% 20
3 MED GENET DEV BIOL 67091 1% 26% 32
4 UMRS 1161 48780 0% 100% 6
5 TISSUE MORPHOGENESIS 37708 1% 22% 21
6 GENET PATHOGENESIS CEREBROVASC DIS 32520 0% 100% 4
7 ACCELERATED VASC 32512 0% 50% 8
8 E365 25403 0% 63% 5
9 D38 24390 0% 100% 3
10 STROKE DEMENTIA 22892 1% 10% 29

Journals


Rank Term Chi square Shr. of publ. in
class containing
term		 Class's shr. of
term's tot. occurrences		 #P with
term in
class
1 BLOOD 3006 3% 0% 116
2 NATO ADVANCED SCIENCE INSTITUTES SERIES, SERIES A, LIFE SCIENCES 2719 0% 3% 11
3 DEVELOPMENTAL CELL 2257 1% 1% 27
4 STROKE 2225 2% 0% 64
5 IMMUNITY 2082 1% 1% 30
6 DEVELOPMENT 1849 1% 0% 55
7 ONCOTARGET 1444 1% 0% 48
8 CANCER CELL 1332 0% 1% 16
9 CANCER RESEARCH 1332 2% 0% 84
10 CIRCULATION RESEARCH 1219 1% 0% 40

Author Key Words


Rank Term Chi square Shr. of publ. in
class containing
term		 Class's shr. of
term's tot. occurrences		 #P with
term in
class		 LCSH search Wikipedia search
1 CADASIL 2755514 11% 85% 397 Search CADASIL Search CADASIL
2 NOTCH3 1214880 5% 80% 187 Search NOTCH3 Search NOTCH3
3 NOTCH 770487 14% 18% 539 Search NOTCH Search NOTCH
4 NOTCH1 738425 7% 37% 246 Search NOTCH1 Search NOTCH1
5 NOTCH SIGNALING 352355 5% 24% 180 Search NOTCH+SIGNALING Search NOTCH+SIGNALING
6 GAMMA SECRETASE INHIBITOR 308523 2% 43% 88 Search GAMMA+SECRETASE+INHIBITOR Search GAMMA+SECRETASE+INHIBITOR
7 NOTCH3 GENE 300812 1% 100% 37 Search NOTCH3+GENE Search NOTCH3+GENE
8 DLL4 256735 1% 69% 46 Search DLL4 Search DLL4
9 JAGGED1 202567 2% 36% 69 Search JAGGED1 Search JAGGED1
10 NOTCH SIGNALING PATHWAY 131360 1% 39% 41 Search NOTCH+SIGNALING+PATHWAY Search NOTCH+SIGNALING+PATHWAY

Core articles
The table includes core articles in the class. The following variables is taken into account for the relevance score of an article in a cluster c:
(1) Number of references referring to publications in the class.
(2) Share of total number of active references referring to publications in the class.
(3) Age of the article. New articles get higher score than old articles.
(4) Citation rate, normalized to year.


Rank Reference # ref. in
cl.		 Shr. of ref. in
cl.		 Citations
1 CHABRIAT, H , JOUTEL, A , DICHGANS, M , TOURNIER-LASSERVE, E , BOUSSER, MG , (2009) CADASIL.LANCET NEUROLOGY. VOL. 8. ISSUE 7. P. 643-653 104 91% 237
2 LEONG, KG , KARSAN, A , (2006) RECENT INSIGHTS INTO THE ROLE OF NOTCH SIGNALING IN TUMORIGENESIS.BLOOD. VOL. 107. ISSUE 6. P. 2223-2233 109 78% 296
3 ANDRE, C , (2010) CADASIL PATHOGENESIS, CLINICAL AND RADIOLOGICAL FINDINGS AND TREATMENT.ARQUIVOS DE NEURO-PSIQUIATRIA. VOL. 68. ISSUE 2. P. 287-299 114 92% 18
4 TIKKA, S , BAUMANN, M , SIITONEN, M , PASANEN, P , POYHONEN, M , MYLLYKANGAS, L , VIITANEN, M , FUKUTAKE, T , COGNAT, E , JOUTEL, A , ET AL (2014) CADASIL AND CARASIL.BRAIN PATHOLOGY. VOL. 24. ISSUE 5. P. 525 -544 97 86% 13
5 GRIDLEY, T , (2010) NOTCH SIGNALING IN THE VASCULATURE.NOTCH SIGNALING. VOL. 92. ISSUE . P. 277-309 103 77% 98
6 NTZIACHRISTOS, P , LIM, JS , SAGE, J , AIFANTIS, I , (2014) FROM FLY WINGS TO TARGETED CANCER THERAPIES: A CENTENNIAL FOR NOTCH SIGNALING.CANCER CELL. VOL. 25. ISSUE 3. P. 318 -334 106 49% 83
7 YAMAMOTO, Y , CRAGGS, L , BAUMANN, M , KALIMO, H , KALARIA, RN , (2011) MOLECULAR GENETICS AND PATHOLOGY OF HEREDITARY SMALL VESSEL DISEASES OF THE BRAIN.NEUROPATHOLOGY AND APPLIED NEUROBIOLOGY. VOL. 37. ISSUE 1. P. 94-113 109 72% 35
8 RUTTEN, JW , HAAN, J , TERWINDT, GM , VAN DUINEN, SG , BOON, EMJ , OBERSTEIN, SAJL , (2014) INTERPRETATION OF NOTCH3 MUTATIONS IN THE DIAGNOSIS OF CADASIL.EXPERT REVIEW OF MOLECULAR DIAGNOSTICS. VOL. 14. ISSUE 5. P. 593-603 78 96% 11
9 ESPINOZA, I , MIELE, L , (2013) NOTCH INHIBITORS FOR CANCER TREATMENT.PHARMACOLOGY & THERAPEUTICS. VOL. 139. ISSUE 2. P. 95-110 121 48% 63
10 HERVE, D , CHABRIAT, H , (2010) CADASIL.JOURNAL OF GERIATRIC PSYCHIATRY AND NEUROLOGY. VOL. 23. ISSUE 4. P. 269-276 82 93% 28

Classes with closest relation at Level 2


Rank Class id link
1 3791 LIPOID PROTEINOSIS//JUVENILE HYALINE FIBROMATOSIS//HAJDU CHENEY SYNDROME
2 1853 CANCER STEM CELLS//CD133//SIDE POPULATION
3 253 DROSOPHILA//DEVELOPMENTAL BIOLOGY//DEVELOPMENT
4 3410 ZEBRAFISH//FACTOR VII ACTIVATING PROTEASE//FSAP
5 3175 ID 1//NRSF//ID1
6 2233 HEART DEVELOPMENT//NKX25//CARDIAC DEVELOPMENT
7 2641 EPITHELIAL MESENCHYMAL TRANSITION//EMT//SNAIL
8 2107 LYMPHANGIOGENESIS//VEGF C//PODOPLANIN
9 1216 PU1//ETS 1//GATA 1
10 1458 SEMAPHORIN//EPHRIN//AXON GUIDANCE

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