Class information for:
Level 2: HMGB1//HIGH MOBILITY GROUP BOX 1//HIGH MOBILITY GROUP BOX 1 PROTEIN

Basic class information
Class id #P Avg. number of
references		 Database coverage
of references
2989 2574 41.5 86%


Bar chart of Publication_year

Last years might be incomplete

Hierarchy of classes
The table includes all classes above and classes immediately below the current class.


Cluster id Level Cluster label #P
0 4 BIOCHEMISTRY & MOLECULAR BIOLOGY//CELL BIOLOGY//ONCOLOGY 4064930
648 3       ADVANCED GLYCATION END PRODUCTS//HMGB1//METHYLGLYOXAL 11882
2989 2             HMGB1//HIGH MOBILITY GROUP BOX 1//HIGH MOBILITY GROUP BOX 1 PROTEIN 2574
4116 1                   HMGB1//HIGH MOBILITY GROUP BOX 1//HIGH MOBILITY GROUP BOX 1 PROTEIN 1844
24837 1                   BERGENIN//BERGENIA//MALLOTUS PHILIPPINENSIS 299
26327 1                   CMRI//BARRIER INTEGRITY//ASIASARI RADIX 257
33828 1                   SALICORNIA HERBACEA//SATOUMI//SALICORNIA HERBACEA L 119
37530 1                   ACERIPHYLLUM ROSSII//ASTILBE CHINENSIS//3 OXOOLEAN 12 EN 27 OIC ACID 55

Terms with highest relevance score


rank Term termType Chi square Shr. of publ. in
class containing
term		 Class's shr. of
term's tot. occurrences		 #P with
term in
class
1 HMGB1 authKW 4004473 22% 59% 572
2 HIGH MOBILITY GROUP BOX 1 authKW 1636158 9% 57% 241
3 HIGH MOBILITY GROUP BOX 1 PROTEIN authKW 564065 3% 66% 72
4 BERGENIN authKW 530133 2% 72% 62
5 CMRI address 418215 3% 49% 72
6 HIGH MOBILITY GROUP BOX 1 HMGB1 authKW 258684 1% 64% 34
7 SALICORNIA HERBACEA authKW 258298 1% 78% 28
8 CHROMATIN DYNAM UNIT address 169434 1% 71% 20
9 HMGB1 PROTEIN authKW 161135 1% 54% 25
10 HIGH MOBILITY GROUP BOX PROTEIN 1 authKW 158493 1% 64% 21

Web of Science journal categories


Rank Term Chi square Shr. of publ. in
class containing
term		 Class's shr. of
term's tot. occurrences		 #P with
term in
class
1 Immunology 2694 17% 0% 435
2 Cell Biology 2023 16% 0% 410
3 Chemistry, Medicinal 1459 8% 0% 199
4 Medicine, Research & Experimental 1149 9% 0% 230
5 Integrative & Complementary Medicine 841 2% 0% 60
6 Pharmacology & Pharmacy 712 12% 0% 312
7 Biochemistry & Molecular Biology 639 17% 0% 443
8 Critical Care Medicine 517 3% 0% 80
9 Oncology 437 9% 0% 227
10 Hematology 430 5% 0% 122

Address terms


Rank Term Chi square Shr. of publ. in
class containing
term		 Class's shr. of
term's tot. occurrences		 #P with
term in
class
1 CMRI 418215 3% 49% 72
2 CHROMATIN DYNAM UNIT 169434 1% 71% 20
3 FATIMA 60039 0% 56% 9
4 ARTHRIT BONE BIOL 56507 0% 53% 9
5 PLUS KNU BIOMED CONVERGENCE PROGRAM BK21 56423 1% 18% 26
6 N SHORE UNIV HOSP 44075 1% 10% 38
7 HERBAL MED PHARMACOL 43728 1% 25% 15
8 PHARMCMRI 37954 0% 80% 4
9 STATE VIRAL HEPATITIS 37954 0% 80% 4
10 ANAT HISTOL 34477 3% 4% 78

Journals


Rank Term Chi square Shr. of publ. in
class containing
term		 Class's shr. of
term's tot. occurrences		 #P with
term in
class
1 MOLECULAR MEDICINE 10431 1% 2% 37
2 INFLAMMATION 3538 1% 1% 28
3 SHOCK 3227 1% 1% 33
4 MEDIATORS OF INFLAMMATION 2558 1% 1% 26
5 BMB REPORTS 2189 1% 1% 14
6 JOURNAL OF LEUKOCYTE BIOLOGY 1913 1% 0% 34
7 ARCHIVES OF PHARMACAL RESEARCH 1683 1% 1% 24
8 INTERNATIONAL IMMUNOPHARMACOLOGY 1539 1% 1% 24
9 ANTIOXIDANTS & REDOX SIGNALING 1082 1% 1% 17
10 MOLECULAR MEDICINE REPORTS 1080 1% 0% 24

Author Key Words


Rank Term Chi square Shr. of publ. in
class containing
term		 Class's shr. of
term's tot. occurrences		 #P with
term in
class		 LCSH search Wikipedia search
1 HMGB1 4004473 22% 59% 572 Search HMGB1 Search HMGB1
2 HIGH MOBILITY GROUP BOX 1 1636158 9% 57% 241 Search HIGH+MOBILITY+GROUP+BOX+1 Search HIGH+MOBILITY+GROUP+BOX+1
3 HIGH MOBILITY GROUP BOX 1 PROTEIN 564065 3% 66% 72 Search HIGH+MOBILITY+GROUP+BOX+1+PROTEIN Search HIGH+MOBILITY+GROUP+BOX+1+PROTEIN
4 BERGENIN 530133 2% 72% 62 Search BERGENIN Search BERGENIN
5 HIGH MOBILITY GROUP BOX 1 HMGB1 258684 1% 64% 34 Search HIGH+MOBILITY+GROUP+BOX+1+HMGB1 Search HIGH+MOBILITY+GROUP+BOX+1+HMGB1
6 SALICORNIA HERBACEA 258298 1% 78% 28 Search SALICORNIA+HERBACEA Search SALICORNIA+HERBACEA
7 HMGB1 PROTEIN 161135 1% 54% 25 Search HMGB1+PROTEIN Search HMGB1+PROTEIN
8 HIGH MOBILITY GROUP BOX PROTEIN 1 158493 1% 64% 21 Search HIGH+MOBILITY+GROUP+BOX+PROTEIN+1 Search HIGH+MOBILITY+GROUP+BOX+PROTEIN+1
9 RAGE 115547 3% 11% 89 Search RAGE Search RAGE
10 HIGH MOBILITY GROUP BOX CHROMOSOMAL PROTEIN 1 106745 0% 75% 12 Search HIGH+MOBILITY+GROUP+BOX+CHROMOSOMAL+PROTEIN+1 Search HIGH+MOBILITY+GROUP+BOX+CHROMOSOMAL+PROTEIN+1

Core articles
The table includes core articles in the class. The following variables is taken into account for the relevance score of an article in a cluster c:
(1) Number of references referring to publications in the class.
(2) Share of total number of active references referring to publications in the class.
(3) Age of the article. New articles get higher score than old articles.
(4) Citation rate, normalized to year.


Rank Reference # ref. in
cl.		 Shr. of ref. in
cl.		 Citations
1 KANG, R , CHEN, RC , ZHANG, QH , HOU, W , WU, S , CAO, LZ , HUANG, J , YU, Y , FAN, XG , YAN, ZW , ET AL (2014) HMGB1 IN HEALTH AND DISEASE.MOLECULAR ASPECTS OF MEDICINE. VOL. 40. ISSUE . P. 1 -116 718 43% 76
2 ANDERSSON, U , TRACEY, KJ , (2011) HMGB1 IS A THERAPEUTIC TARGET FOR STERILE INFLAMMATION AND INFECTION.ANNUAL REVIEW OF IMMUNOLOGY, VOL 29. VOL. 29. ISSUE . P. 139 -162 106 79% 417
3 TSUNG, A , TOHME, S , BILLIAR, TR , (2014) HIGH-MOBILITY GROUP BOX-1 IN STERILE INFLAMMATION.JOURNAL OF INTERNAL MEDICINE. VOL. 276. ISSUE 5. P. 425 -443 123 66% 49
4 YANG, S , XU, LXY , YANG, TS , WANG, F , (2014) HIGH-MOBILITY GROUP BOX-1 AND ITS ROLE IN ANGIOGENESIS.JOURNAL OF LEUKOCYTE BIOLOGY. VOL. 95. ISSUE 4. P. 563 -574 106 76% 21
5 CAI, JJ , WEN, J , BAUER, E , ZHONG, H , YUAN, H , CHEN, AF , (2015) THE ROLE OF HMGB1 IN CARDIOVASCULAR BIOLOGY: DANGER SIGNALS.ANTIOXIDANTS & REDOX SIGNALING. VOL. 23. ISSUE 17. P. 1351 -1369 124 63% 8
6 KLUNE, JR , DHUPAR, R , CARDINAL, J , BILLIAR, TR , TSUNG, A , (2008) HMGB1: ENDOGENOUS DANGER SIGNALING.MOLECULAR MEDICINE. VOL. 14. ISSUE 7-8. P. 476-484 83 69% 322
7 TANG, DL , KANG, R , ZEH, HJ , LOTZE, MT , (2011) HIGH-MOBILITY GROUP BOX 1, OXIDATIVE STRESS, AND DISEASE.ANTIOXIDANTS & REDOX SIGNALING. VOL. 14. ISSUE 7. P. 1315 -1335 120 47% 150
8 DE SOUZA, AWS , WESTRA, J , LIMBURG, PC , BIJL, M , KALLENBERG, CGM , (2012) HMGB1 IN VASCULAR DISEASES: ITS ROLE IN VASCULAR INFLAMMATION AND ATHEROSCLEROSIS.AUTOIMMUNITY REVIEWS. VOL. 11. ISSUE 12. P. 909-917 81 83% 47
9 HARRIS, HE , ANDERSSON, U , PISETSKY, DS , (2012) HMGB1: A MULTIFUNCTIONAL ALARMIN DRIVING AUTOIMMUNE AND INFLAMMATORY DISEASE.NATURE REVIEWS RHEUMATOLOGY. VOL. 8. ISSUE 4. P. 195 -202 62 78% 179
10 VENEREAU, E , DE LEO, F , MEZZAPELLE, R , CARECCIA, G , MUSCO, G , BIANCHI, ME , (2016) HMGB1 AS BIOMARKER AND DRUG TARGET.PHARMACOLOGICAL RESEARCH. VOL. 111. ISSUE . P. 534 -544 89 74% 1

Classes with closest relation at Level 2


Rank Class id link
1 1179 ADVANCED GLYCATION END PRODUCTS//METHYLGLYOXAL//GLYCATION
2 3046 PROGRAM TRANSLAT IMMUNOVIROL BIODEF//MAYO VACCINE GRP//SEPSIS
3 1094 NUCLEAR MATRIX//LINKER HISTONE//HISTONE H1
4 3315 GLYCYRRHIZIN//LICORICE//GLYCYRRHIZIC ACID
5 543 TOLL LIKE RECEPTORS//INNATE IMMUNITY//CPG ODN
6 2102 FAMILIAL MEDITERRANEAN FEVER//INFLAMMASOME//NLRP3
7 2683 NEUTROPHIL EXTRACELLULAR TRAPS//SEVERE CONGENITAL NEUTROPENIA//NETOSIS
8 2259 METABOTROPIC GLUTAMATE RECEPTOR//MGLUR5//MPEP
9 1128 AUTOPHAGY//BECLIN 1//LC3
10 2796 GALLIC ACID//COROSOLIC ACID//ELLAGITANNINS

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