Class information for:
Level 2: DIMEBON//REMOXIPRIDE//LATREPIRDINE

Basic class information
Class id #P Avg. number of
references		 Database coverage
of references
3387 1644 24.5 41%


Bar chart of Publication_year

Last years might be incomplete

Hierarchy of classes
The table includes all classes above and classes immediately below the current class.


Cluster id Level Cluster label #P
1 4 ECONOMICS//EDUCATION & EDUCATIONAL RESEARCH//PSYCHOL 3876184
110 3       PSYCHIATRY//SCHIZOPHRENIA//BIPOLAR DISORDER 71389
3387 2             DIMEBON//REMOXIPRIDE//LATREPIRDINE 1644
22258 1                   REMOXIPRIDE//AGONIST ANTAGONIST INTERACTION MODEL//1 2 DIAMINOCYCLOPROPANE 388
22710 1                   ACTIVITAS NERVOSA SUPERIOR//COLLECTION OF CZECHOSLOVAK CHEMICAL COMMUNICATIONS//11 4 CINNAMYL 1 PIPERAZINYL 6 11 DIHYDRODIBENZB EOXEPIN 371
24718 1                   MEBEVERINE//LEVOSULPIRIDE//MEBEVERINE HYDROCHLORIDE 303
28623 1                   DIMEBON//LATREPIRDINE//DIMEBOLIN 203
28884 1                   METOCLOPRAMIDE//BROMOPRIDE//METOCLOPRAMIDE HYDROCHLORIDE 197
29689 1                   6 11 DIHYDRODIBENZB EOXEPIN//DIBENZOSUBERONE//ANTI PASSIVE CUTANEOUS ANAPHYLAXIS ACTIVITY 182

Terms with highest relevance score


rank Term termType Chi square Shr. of publ. in
class containing
term		 Class's shr. of
term's tot. occurrences		 #P with
term in
class
1 DIMEBON authKW 405613 2% 70% 31
2 REMOXIPRIDE authKW 235884 2% 37% 34
3 LATREPIRDINE authKW 168835 1% 91% 10
4 ACTIVITAS NERVOSA SUPERIOR journal 157030 5% 9% 90
5 DIMEBOLIN authKW 118858 0% 80% 8
6 MEBEVERINE authKW 116266 1% 52% 12
7 LEVOSULPIRIDE authKW 116234 1% 48% 13
8 NEURONAL NMDA RECEPTORS authKW 92861 0% 100% 5
9 METOCLOPRAMIDE authKW 87001 3% 9% 55
10 MEBEVERINE HYDROCHLORIDE authKW 84408 1% 45% 10

Web of Science journal categories


Rank Term Chi square Shr. of publ. in
class containing
term		 Class's shr. of
term's tot. occurrences		 #P with
term in
class
1 Pharmacology & Pharmacy 4600 32% 0% 526
2 Chemistry, Medicinal 2654 12% 0% 205
3 Chemistry, Multidisciplinary 1729 23% 0% 377
4 Psychiatry 945 10% 0% 158
5 Chemistry, Analytical 725 10% 0% 170
6 Crystallography 679 6% 0% 100
7 Neurosciences 562 13% 0% 215
8 Clinical Neurology 407 8% 0% 137
9 Chemistry, Organic 289 8% 0% 125
10 Biochemical Research Methods 137 4% 0% 66

Address terms


Rank Term Chi square Shr. of publ. in
class containing
term		 Class's shr. of
term's tot. occurrences		 #P with
term in
class
1 SECT MOL ECOGENET 37140 0% 50% 4
2 PHARMACEUT S 1188 SHIMOTOGARI 33427 0% 60% 3
3 PHYS CHEM IND CATALYSIS 31829 0% 29% 6
4 MOL BIOL HIGH THROUGHPUT SCREENING 24761 0% 67% 2
5 MOL ECOGENET GRP 24761 0% 67% 2
6 MOL STEM CELL PHARMACOL 23875 0% 43% 3
7 ABT GALEN 18572 0% 100% 1
8 ANORGAN DIDAKT CHEM 18572 0% 100% 1
9 BERLIN CLIN TERATOL 18572 0% 100% 1
10 BIOANAL ANALYT PHARMACEUT RD 18572 0% 100% 1

Journals


Rank Term Chi square Shr. of publ. in
class containing
term		 Class's shr. of
term's tot. occurrences		 #P with
term in
class
1 ACTIVITAS NERVOSA SUPERIOR 157030 5% 9% 90
2 COLLECTION OF CZECHOSLOVAK CHEMICAL COMMUNICATIONS 61233 9% 2% 155
3 ACTA PSYCHIATRICA SCANDINAVICA 4617 2% 1% 39
4 SEMAINE DES HOPITAUX 2859 1% 1% 23
5 JOURNAL OF MEDICINAL CHEMISTRY 2633 3% 0% 56
6 ACTA PHARMACEUTICA NORDICA 2460 0% 3% 5
7 JOURNAL OF CRYSTALLOGRAPHIC AND SPECTROSCOPIC RESEARCH 2230 1% 1% 11
8 ARZNEIMITTEL-FORSCHUNG/DRUG RESEARCH 1493 1% 0% 19
9 ACTA CRYSTALLOGRAPHICA SECTION C-CRYSTAL STRUCTURE COMMUNICATIONS 1370 2% 0% 28
10 PSYCHOPHARMACOLOGY 1335 2% 0% 30

Author Key Words


Rank Term Chi square Shr. of publ. in
class containing
term		 Class's shr. of
term's tot. occurrences		 #P with
term in
class		 LCSH search Wikipedia search
1 DIMEBON 405613 2% 70% 31 Search DIMEBON Search DIMEBON
2 REMOXIPRIDE 235884 2% 37% 34 Search REMOXIPRIDE Search REMOXIPRIDE
3 LATREPIRDINE 168835 1% 91% 10 Search LATREPIRDINE Search LATREPIRDINE
4 DIMEBOLIN 118858 0% 80% 8 Search DIMEBOLIN Search DIMEBOLIN
5 MEBEVERINE 116266 1% 52% 12 Search MEBEVERINE Search MEBEVERINE
6 LEVOSULPIRIDE 116234 1% 48% 13 Search LEVOSULPIRIDE Search LEVOSULPIRIDE
7 NEURONAL NMDA RECEPTORS 92861 0% 100% 5 Search NEURONAL+NMDA+RECEPTORS Search NEURONAL+NMDA+RECEPTORS
8 METOCLOPRAMIDE 87001 3% 9% 55 Search METOCLOPRAMIDE Search METOCLOPRAMIDE
9 MEBEVERINE HYDROCHLORIDE 84408 1% 45% 10 Search MEBEVERINE+HYDROCHLORIDE Search MEBEVERINE+HYDROCHLORIDE
10 GAMMA CARBOLINES 83565 1% 50% 9 Search GAMMA+CARBOLINES Search GAMMA+CARBOLINES

Core articles
The table includes core articles in the class. The following variables is taken into account for the relevance score of an article in a cluster c:
(1) Number of references referring to publications in the class.
(2) Share of total number of active references referring to publications in the class.
(3) Age of the article. New articles get higher score than old articles.
(4) Citation rate, normalized to year.


Rank Reference # ref. in
cl.		 Shr. of ref. in
cl.		 Citations
1 PROTIVA, M , (1991) 50 YEARS IN CHEMICAL DRUG RESEARCH.COLLECTION OF CZECHOSLOVAK CHEMICAL COMMUNICATIONS. VOL. 56. ISSUE 11B. P. 2501-2771 232 77% 3
2 PROTIVA, M , (1996) THE PLACE OF DIBENZO[B,F]THIEPIN DERIVATIVES IN MEDICINAL CHEMISTRY: STRUCTURES AND ACTIVITIES.JOURNAL OF HETEROCYCLIC CHEMISTRY. VOL. 33. ISSUE 3. P. 497-521 110 73% 9
3 CANO-CUENCA, N , DEL POZO, JSG , JORDAN, J , (2015) LATREPIRDINE: A SYSTEMATIC REVIEW OF THE PRECLINICAL STUDIES.REVISTA DE NEUROLOGIA. VOL. 60. ISSUE 1. P. 35 -42 31 67% 0
4 NAGUIB, IA , ABDELKAWY, M , (2010) DEVELOPMENT AND VALIDATION OF STABILITY INDICATING HPLC AND HPTLC METHODS FOR DETERMINATION OF SULPIRIDE AND MEBEVERINE HYDROCHLORIDE IN COMBINATION.EUROPEAN JOURNAL OF MEDICINAL CHEMISTRY. VOL. 45. ISSUE 9. P. 3719-3725 34 62% 17
5 WADWORTH, AN , HEEL, RC , (1990) REMOXIPRIDE - A REVIEW OF ITS PHARMACODYNAMIC AND PHARMACOKINETIC PROPERTIES, AND THERAPEUTIC POTENTIAL IN SCHIZOPHRENIA.DRUGS. VOL. 40. ISSUE 6. P. 863-879 43 86% 48
6 DEVI, OZ , BASAVAIAH, K , VINAY, KB , REVANASIDDAPPA, HD , (2012) DETERMINATION OF METOCLOPRAMIDE HYDROCHLORIDE IN PHARMACEUTICALS AND SPIKED HUMAN URINE THROUGH DIAZOTIZATION REACTION.JOURNAL OF FOOD AND DRUG ANALYSIS. VOL. 20. ISSUE 2. P. 454-463 23 82% 2
7 PETERS, OM , SHELKOVNIKOVA, T , TARASOVA, T , SPRINGE, S , KUKHARSKY, MS , SMITH, GA , BROOKS, S , KOZIN, SA , KOTELEVTSEVE, Y , BACHURIN, SO , ET AL (2013) CHRONIC ADMINISTRATION OF DIMEBON DOES NOT AMELIORATE AMYLOID-BETA PATHOLOGY IN 5XFAD TRANSGENIC MICE.JOURNAL OF ALZHEIMERS DISEASE. VOL. 36. ISSUE 3. P. 589-596 20 87% 8
8 USTYUGOV, A , SHEVTSOVA, E , BACHURIN, S , (2015) NOVEL SITES OF NEUROPROTECTIVE ACTION OF DIMEBON (LATREPIRDINE).MOLECULAR NEUROBIOLOGY. VOL. 52. ISSUE 2. P. 970 -978 28 56% 1
9 WALASH, M , EL-DIN, MS , EL-ENANY, N , EID, M , SHALAN, S , (2010) FIRST DERIVATIVE SYNCHRONOUS FLUORESCENCE SPECTROSCOPY FOR THE SIMULTANEOUS DETERMINATION OF SULPIRIDE AND MEBEVERINE HYDROCHLORIDE IN THEIR COMBINED TABLETS AND APPLICATION TO REAL HUMAN PLASMA.JOURNAL OF FLUORESCENCE. VOL. 20. ISSUE 6. P. 1275-1285 25 68% 15
10 LOUDERBACK, KM , WILLS, TA , MUGLIA, LJ , WINDER, DG , (2013) KNOCKDOWN OF BNST GLUN2B-CONTAINING NMDA RECEPTORS MIMICS THE ACTIONS OF KETAMINE ON NOVELTY-INDUCED HYPOPHAGIA.TRANSLATIONAL PSYCHIATRY. VOL. 3. ISSUE . P. - 33 49% 4

Classes with closest relation at Level 2


Rank Class id link
1 2247 TARDIVE DYSKINESIA//AKATHISIA//VACUOUS CHEWING MOVEMENTS
2 3963 1 RUE VAUBENARD//ISOTELLUROCHROMENE//PHARM KANAGAWA MACHI
3 2035 ANTIEMETICS//EMESIS//VOMITING
4 1400 FLUORINE 18//C 11RACLOPRIDE//POSITRON EMISSION TOMOGRAPHY
5 75 NUCLEUS ACCUMBENS//DOPAMINE//COCAINE
6 617 ANTIPSYCHOTICS//CLOZAPINE//SCHIZOPHRENIA
7 2031 PARACETAMOL//MICROEXTRACTION IN PACKED SYRINGE//CHEMISTRY, ANALYTICAL
8 3951 NEFOPAM//ACRIVASTINE//METHAPYRILENE
9 3679 ADRENERGIC DRUG//FARMACO-EDIZIONE SCIENTIFICA//1 2 4TRIAZOLO1 5 AQUINOLINES
10 4156 ADDICT NIH HLTH HUMAN SERV//CITDHHS//DRUG DESIGN SYNTH SECT

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