Class information for:
Level 1: REDUCED FOLATE CARRIER//FOLYLPOLYGLUTAMATE SYNTHETASE//ANTIFOLATE

Basic class information
Bar chart of Publication_year

Last years might be incomplete

Hierarchy of classes
The table includes all classes above and classes immediately below the current class.


Cluster id Level Cluster label #P
0 4 ONCOLOGY//CELL BIOLOGY//BIOCHEMISTRY & MOLECULAR BIOLOGY 2934640
200 3       ONCOLOGY//PACLITAXEL//THYMIDYLATE SYNTHASE 52806
1389 2             PEMETREXED//NON SMALL CELL LUNG CANCER//ANTIFOLATE 8368
2087 1                   REDUCED FOLATE CARRIER//FOLYLPOLYGLUTAMATE SYNTHETASE//ANTIFOLATE 2396

Terms with highest relevance score


rank Category termType chi_square shrOfCwithTerm shrOfTermInClass termInClass
1 REDUCED FOLATE CARRIER authKW 697693 4% 63% 84
2 FOLYLPOLYGLUTAMATE SYNTHETASE authKW 488728 2% 77% 48
3 ANTIFOLATE authKW 479192 5% 33% 110
4 PCFT authKW 283444 1% 86% 25
5 TRIMETREXATE authKW 243036 1% 60% 31
6 PROTON COUPLED FOLATE TRANSPORTER authKW 227953 1% 67% 26
7 HEREDITARY FOLATE MALABSORPTION authKW 223586 1% 100% 17
8 FOLATE TRANSPORT authKW 216831 1% 63% 26
9 EXPT CLIN THER EUT PROGRAM address 210410 1% 57% 28
10 EDATREXATE authKW 181396 1% 69% 20

Web of Science journal categories


chi_square_rank Category chi_square shrOfCwithTerm shrOfTermInClass termInClass
1 Oncology 7454 30% 0% 718
2 Chemistry, Medicinal 3343 12% 0% 279
3 Pharmacology & Pharmacy 2354 20% 0% 482
4 Biochemistry & Molecular Biology 1707 25% 0% 604
5 Chemistry, Organic 385 7% 0% 175
6 Biophysics 343 5% 0% 129
7 Hematology 205 4% 0% 87
8 Nutrition & Dietetics 124 3% 0% 61
9 Biochemical Research Methods 103 3% 0% 76
10 Physiology 65 3% 0% 68

Address terms


chi_square_rank term chi_square shrOfCwithTerm shrOfTermInClass termInClass
1 EXPT CLIN THER EUT PROGRAM 210410 1% 57% 28
2 PROGRAM MOL PHARMACOL EXPT THER EUT 92460 1% 47% 15
3 FRED WYSZKOWSKI CANC 60849 1% 26% 18
4 GRACE CANC DRUG 41472 1% 13% 25
5 ALBERT E EIN COMPREHENS CANC 30043 1% 19% 12
6 CATTEDRA PATOL GEN 3 26304 0% 100% 2
7 GRACE CANC DRUG EXPTL THER EUT 26304 0% 100% 2
8 MOLEC EXPTL MED NX6 26304 0% 100% 2
9 MOLEC THER EUT 26304 0% 100% 2
10 TAKEDA RABICS 26304 0% 100% 2

Journals


chi_square_rank term chi_square shrOfCwithTerm shrOfTermInClass termInClass
1 JOURNAL OF MEDICINAL CHEMISTRY 17264 7% 1% 170
2 ADVANCES IN ENZYME REGULATION 16036 1% 5% 27
3 CANCER CHEMOTHERAPY AND PHARMACOLOGY 11409 3% 1% 81
4 BIOCHEMICAL PHARMACOLOGY 10537 5% 1% 123
5 CANCER RESEARCH 7152 6% 0% 148
6 INVESTIGATIONAL NEW DRUGS 5139 1% 1% 32
7 MOLECULAR PHARMACOLOGY 3538 2% 1% 52
8 CLINICAL CANCER RESEARCH 3107 3% 0% 61
9 PTERIDINES 2032 0% 2% 8
10 JOURNAL OF BIOLOGICAL CHEMISTRY 1907 7% 0% 157

Author Key Words


chi_square_rank term chi_square shrOfCwithTerm shrOfTermInClass termInClass LCSH search Wikipedia search
1 REDUCED FOLATE CARRIER 697693 4% 63% 84 Search REDUCED+FOLATE+CARRIER Search REDUCED+FOLATE+CARRIER
2 FOLYLPOLYGLUTAMATE SYNTHETASE 488728 2% 77% 48 Search FOLYLPOLYGLUTAMATE+SYNTHETASE Search FOLYLPOLYGLUTAMATE+SYNTHETASE
3 ANTIFOLATE 479192 5% 33% 110 Search ANTIFOLATE Search ANTIFOLATE
4 PCFT 283444 1% 86% 25 Search PCFT Search PCFT
5 TRIMETREXATE 243036 1% 60% 31 Search TRIMETREXATE Search TRIMETREXATE
6 PROTON COUPLED FOLATE TRANSPORTER 227953 1% 67% 26 Search PROTON+COUPLED+FOLATE+TRANSPORTER Search PROTON+COUPLED+FOLATE+TRANSPORTER
7 HEREDITARY FOLATE MALABSORPTION 223586 1% 100% 17 Search HEREDITARY+FOLATE+MALABSORPTION Search HEREDITARY+FOLATE+MALABSORPTION
8 FOLATE TRANSPORT 216831 1% 63% 26 Search FOLATE+TRANSPORT Search FOLATE+TRANSPORT
9 EDATREXATE 181396 1% 69% 20 Search EDATREXATE Search EDATREXATE
10 POLYGLUTAMATION 172763 1% 77% 17 Search POLYGLUTAMATION Search POLYGLUTAMATION

Core articles
The table includes core articles in the class. The following variables is taken into account for the relevance score of an article in a cluster c:
(1) Number of references referring to publications in the class.
(2) Share of total number of active references referring to publications in the class.
(3) Age of the article. New articles get higher score than old articles.
(4) Citation rate, normalized to year.

Classes with closest relation at Level 1


rank cluster_id2 link
1 24587 PEMETREXED//MULTITARGETED ANTIFOLATE//PEMETREXED DISODIUM
2 15949 HIGH DOSE METHOTREXATE//7 HYDROXYMETHOTREXATE//GLUCARPIDASE
3 9209 FOLATE RECEPTOR//FOLATE BINDING PROTEIN//FOLATE RECEPTOR ALPHA
4 18645 HPPK//DIHYDROFOLATE REDUCTASE//DIHYDROPTEROATE SYNTHASE
5 17615 THYMIDYLATE SYNTHASE//THYX//DEOXYTUBULOSINE
6 37378 CEREBRAL FOLATE DEFICIENCY//FOLATE RECEPTOR AUTOANTIBODY//FOLATE RECEPTOR ANTIBODY
7 14068 SERINE HYDROXYMETHYLTRANSFERASE//THREONINE ALDOLASE//SHMT
8 22019 PURINE BIOSYNTHESIS//PURK//AIR CARBOXYLASE
9 8193 FOLATE//FOOD FOLATE//FOLIC ACID
10 6087 METHOTREXATE//METHOTREXATE POLYGLUTAMATES//RHEUMATOID ARTHRITIS

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