Class information for:
Level 1: BACE1//BETA SECRETASE//BACE1 INHIBITOR

Basic class information
Bar chart of Publication_year

Last years might be incomplete

Hierarchy of classes
The table includes all classes above and classes immediately below the current class.


Cluster id Level Cluster label #P
5 4 NEUROSCIENCES//CLINICAL NEUROLOGY//PSYCHOLOGY, EXPERIMENTAL 1830502
56 3       ALZHEIMERS DISEASE//DEMENTIA//GERIATRICS & GERONTOLOGY 94559
16 2             ALZHEIMERS DISEASE//AMYLOID//AMYLOID BETA 37707
8922 1                   BACE1//BETA SECRETASE//BACE1 INHIBITOR 1234

Terms with highest relevance score


rank Category termType chi_square shrOfCwithTerm shrOfTermInClass termInClass
1 BACE1 authKW 3895288 23% 53% 287
2 BETA SECRETASE authKW 2881820 18% 52% 219
3 BACE1 INHIBITOR authKW 1308924 5% 83% 62
4 BACE authKW 1133263 7% 53% 84
5 PROT STUDIES PROGRAM address 485198 3% 50% 38
6 MEMAPSIN 2 authKW 459697 1% 100% 18
7 BACE2 authKW 445754 2% 73% 24
8 BETA SECRETASE INHIBITOR authKW 274677 2% 51% 21
9 SECRETASE authKW 232089 4% 18% 50
10 BETA SECRETASE BACE1 authKW 196447 1% 77% 10

Web of Science journal categories


chi_square_rank Category chi_square shrOfCwithTerm shrOfTermInClass termInClass
1 Chemistry, Medicinal 8987 26% 0% 315
2 Neurosciences 2763 29% 0% 355
3 Biochemistry & Molecular Biology 1708 33% 0% 407
4 Chemistry, Organic 922 14% 0% 168
5 Pharmacology & Pharmacy 166 9% 0% 115
6 Geriatrics & Gerontology 152 2% 0% 27
7 Cell Biology 146 8% 0% 94
8 Biophysics 112 5% 0% 56
9 Clinical Neurology 87 5% 0% 65
10 Biochemical Research Methods 45 3% 0% 37

Address terms


chi_square_rank term chi_square shrOfCwithTerm shrOfTermInClass termInClass
1 PROT STUDIES PROGRAM 485198 3% 50% 38
2 PEPTIDE SCI 71054 1% 35% 8
3 PROTEOM SCI 68101 0% 67% 4
4 GLYCO CHAIN FUNCT 63842 0% 50% 5
5 GRP QUIM BIOORGAN 57461 0% 75% 3
6 NEUROSCI WORLDWIDE MED CHEM 57461 0% 75% 3
7 MUNICH BIOCHEM 51077 0% 100% 2
8 OKLAHOMA MED FDN 46194 1% 10% 18
9 HALDEMAN MOL DIAGNOST THER EUT 45967 0% 60% 3
10 NEUROL GASTROINTESTINAL EXCELLENCE DRUG DIS 38101 1% 15% 10

Journals


chi_square_rank term chi_square shrOfCwithTerm shrOfTermInClass termInClass
1 BIOORGANIC & MEDICINAL CHEMISTRY LETTERS 14422 10% 0% 121
2 MOLECULAR NEURODEGENERATION 10480 1% 3% 16
3 CURRENT ALZHEIMER RESEARCH 5496 1% 1% 15
4 JOURNAL OF MEDICINAL CHEMISTRY 5020 5% 0% 66
5 JOURNAL OF ALZHEIMERS DISEASE 3432 2% 1% 26
6 NEURODEGENERATIVE DISEASES 2391 1% 1% 8
7 JOURNAL OF NEUROCHEMISTRY 1519 3% 0% 36
8 BIOORGANIC & MEDICINAL CHEMISTRY 1148 2% 0% 25
9 JOURNAL OF MOLECULAR NEUROSCIENCE 1075 1% 0% 11
10 JOURNAL OF BIOLOGICAL CHEMISTRY 960 6% 0% 80

Author Key Words


chi_square_rank term chi_square shrOfCwithTerm shrOfTermInClass termInClass LCSH search Wikipedia search
1 BACE1 3895288 23% 53% 287 Search BACE1 Search BACE1
2 BETA SECRETASE 2881820 18% 52% 219 Search BETA+SECRETASE Search BETA+SECRETASE
3 BACE1 INHIBITOR 1308924 5% 83% 62 Search BACE1+INHIBITOR Search BACE1+INHIBITOR
4 BACE 1133263 7% 53% 84 Search BACE Search BACE
5 MEMAPSIN 2 459697 1% 100% 18 Search MEMAPSIN+2 Search MEMAPSIN+2
6 BACE2 445754 2% 73% 24 Search BACE2 Search BACE2
7 BETA SECRETASE INHIBITOR 274677 2% 51% 21 Search BETA+SECRETASE+INHIBITOR Search BETA+SECRETASE+INHIBITOR
8 SECRETASE 232089 4% 18% 50 Search SECRETASE Search SECRETASE
9 BETA SECRETASE BACE1 196447 1% 77% 10 Search BETA+SECRETASE+BACE1 Search BETA+SECRETASE+BACE1
10 BACE INHIBITOR 188055 1% 82% 9 Search BACE+INHIBITOR Search BACE+INHIBITOR

Core articles
The table includes core articles in the class. The following variables is taken into account for the relevance score of an article in a cluster c:
(1) Number of references referring to publications in the class.
(2) Share of total number of active references referring to publications in the class.
(3) Age of the article. New articles get higher score than old articles.
(4) Citation rate, normalized to year.

Classes with closest relation at Level 1


rank cluster_id2 link
1 1152 PRESENILIN//GAMMA SECRETASE//PRESENILIN 1
2 10321 FE65//AMYLOID PRECURSOR PROTEIN//APP
3 8654 INTRANEURONAL A BETA//TG2576//ALZHEIMERS DISEASE
4 23684 GLUTAMINYL CYCLASE//FAMILIAL DANISH DEMENTIA//FAMILIAL BRITISH DEMENTIA
5 9874 BAPINEUZUMAB//SOLANEZUMAB//GANTENERUMAB
6 1712 AMYLOID PRECURSOR PROTEIN//BETA AMYLOID PRECURSOR PROTEIN//ALZHEIMERS DISEASE
7 20085 NEPRILYSIN//ENDOTHELIN CONVERTING ENZYME//ENDOTHELIN CONVERTING ENZYME 1
8 32168 HEPARIN DERIVED OLIGOSACCHARIDE//ACIDIC OLIGOSACCHARIDE SUGAR CHAIN//AOSC
9 2848 ACETYLCHOLINESTERASE//BUTYRYLCHOLINESTERASE//ACETYLCHOLINESTERASE INHIBITORS
10 30691 MEMORY AND LEARNING IMPAIRMENT//ALZHEIMER KOR KUTATOCSOPORT//KORELETTANI INT

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