Class information for:
Level 1: PCSK9//PROPROTEIN CONVERTASE SUBTILISIN KEXIN TYPE 9//ALIROCUMAB

Basic class information
Bar chart of Publication_year

Last years might be incomplete

Hierarchy of classes
The table includes all classes above and classes immediately below the current class.


Cluster id Level Cluster label #P
7 4 CARDIAC & CARDIOVASCULAR SYSTEM//PERIPHERAL VASCULAR DISEASES//CARDIOL 1572904
98 3       STATINS//JOURNAL OF LIPID RESEARCH//LIPOPROTEINS 77402
373 2             STATINS//EZETIMIBE//SIMVASTATIN 17683
9658 1                   PCSK9//PROPROTEIN CONVERTASE SUBTILISIN KEXIN TYPE 9//ALIROCUMAB 1165

Terms with highest relevance score


rank Category termType chi_square shrOfCwithTerm shrOfTermInClass termInClass
1 PCSK9 authKW 5734274 25% 73% 289
2 PROPROTEIN CONVERTASE SUBTILISIN KEXIN TYPE 9 authKW 2645014 10% 84% 117
3 ALIROCUMAB authKW 1512200 5% 89% 63
4 PCSK9 INHIBITORS authKW 891862 4% 70% 47
5 EVOLOCUMAB authKW 867594 4% 76% 42
6 PROPROTEIN CONVERTASE SUBTILISIN authKW 373111 2% 69% 20
7 PROPROTEIN CONVERTASE SUBTILISIN KEXIN 9 authKW 326548 1% 93% 13
8 BIOCHEM NEUROENDOCRINOL address 302144 5% 21% 54
9 PROPROTEIN CONVERTASE SUBTILISIN KEXIN TYPE 9 PCSK9 authKW 276653 1% 68% 15
10 LOW DENSITY LIPOPROTEIN CHOLESTEROL authKW 260516 8% 11% 89

Web of Science journal categories


chi_square_rank Category chi_square shrOfCwithTerm shrOfTermInClass termInClass
1 Cardiac & Cardiovascular System 7270 31% 0% 366
2 Peripheral Vascular Diseases 3685 17% 0% 197
3 Biochemistry & Molecular Biology 568 22% 0% 254
4 Endocrinology & Metabolism 459 9% 0% 102
5 Pharmacology & Pharmacy 458 14% 0% 161
6 Medicine, General & Internal 366 10% 0% 113
7 Medicine, Research & Experimental 173 6% 0% 67
8 Hematology 131 4% 0% 47
9 Nutrition & Dietetics 123 3% 0% 39
10 Medical Laboratory Technology 102 2% 0% 21

Address terms


chi_square_rank term chi_square shrOfCwithTerm shrOfTermInClass termInClass
1 BIOCHEM NEUROENDOCRINOL 302144 5% 21% 54
2 CARBOHYDRATE LIPID METAB UNIT 141309 1% 33% 16
3 DEV LAUNCH UNIT PCSK9 108206 0% 100% 4
4 DYSLIPIDEMIASTATE CARDIOVASC DIS 97368 1% 30% 12
5 IMPERIAL CARDIOVASC DIS PREVENT 96609 0% 71% 5
6 ENDOCRINOL METABCLIN 81154 0% 100% 3
7 CLIN MALAD LIPID 60864 0% 75% 3
8 LIPIDOL 58499 1% 14% 15
9 SOC ITALIANA STUDIO ATEROSCLEROSI 57278 1% 35% 6
10 UNIT CARDIAC CARDIOVASC GENET 55220 1% 29% 7

Journals


chi_square_rank term chi_square shrOfCwithTerm shrOfTermInClass termInClass
1 JOURNAL OF CLINICAL LIPIDOLOGY 42656 3% 5% 34
2 CURRENT OPINION IN LIPIDOLOGY 16574 2% 2% 29
3 ATHEROSCLEROSIS 10179 5% 1% 64
4 CURRENT ATHEROSCLEROSIS REPORTS 10049 1% 2% 16
5 CLINICAL LIPIDOLOGY 7062 1% 3% 10
6 JOURNAL OF LIPID RESEARCH 6554 4% 1% 46
7 LIPIDS IN HEALTH AND DISEASE 5254 2% 1% 18
8 AMERICAN JOURNAL OF CARDIOVASCULAR DRUGS 3901 1% 2% 8
9 ARTERIOSCLEROSIS THROMBOSIS AND VASCULAR BIOLOGY 3820 3% 0% 33
10 ATHEROSCLEROSIS SUPPLEMENTS 3429 1% 2% 6

Author Key Words


chi_square_rank term chi_square shrOfCwithTerm shrOfTermInClass termInClass LCSH search Wikipedia search
1 PCSK9 5734274 25% 73% 289 Search PCSK9 Search PCSK9
2 PROPROTEIN CONVERTASE SUBTILISIN KEXIN TYPE 9 2645014 10% 84% 117 Search PROPROTEIN+CONVERTASE+SUBTILISIN+KEXIN+TYPE+9 Search PROPROTEIN+CONVERTASE+SUBTILISIN+KEXIN+TYPE+9
3 ALIROCUMAB 1512200 5% 89% 63 Search ALIROCUMAB Search ALIROCUMAB
4 PCSK9 INHIBITORS 891862 4% 70% 47 Search PCSK9+INHIBITORS Search PCSK9+INHIBITORS
5 EVOLOCUMAB 867594 4% 76% 42 Search EVOLOCUMAB Search EVOLOCUMAB
6 PROPROTEIN CONVERTASE SUBTILISIN 373111 2% 69% 20 Search PROPROTEIN+CONVERTASE+SUBTILISIN Search PROPROTEIN+CONVERTASE+SUBTILISIN
7 PROPROTEIN CONVERTASE SUBTILISIN KEXIN 9 326548 1% 93% 13 Search PROPROTEIN+CONVERTASE+SUBTILISIN+KEXIN+9 Search PROPROTEIN+CONVERTASE+SUBTILISIN+KEXIN+9
8 PROPROTEIN CONVERTASE SUBTILISIN KEXIN TYPE 9 PCSK9 276653 1% 68% 15 Search PROPROTEIN+CONVERTASE+SUBTILISIN+KEXIN+TYPE+9+PCSK9 Search PROPROTEIN+CONVERTASE+SUBTILISIN+KEXIN+TYPE+9+PCSK9
9 LOW DENSITY LIPOPROTEIN CHOLESTEROL 260516 8% 11% 89 Search LOW+DENSITY+LIPOPROTEIN+CHOLESTEROL Search LOW+DENSITY+LIPOPROTEIN+CHOLESTEROL
10 AMG 145 243463 1% 100% 9 Search AMG+145 Search AMG+145

Core articles
The table includes core articles in the class. The following variables is taken into account for the relevance score of an article in a cluster c:
(1) Number of references referring to publications in the class.
(2) Share of total number of active references referring to publications in the class.
(3) Age of the article. New articles get higher score than old articles.
(4) Citation rate, normalized to year.

Classes with closest relation at Level 1


rank cluster_id2 link
1 3551 FAMILIAL HYPERCHOLESTEROLEMIA//FAMILIAL HYPERCHOLESTEROLAEMIA//MIPOMERSEN
2 18982 STATINS//HIGH INTENSITY STATINS//IR DEPENDENT IRS 1 PI3K AKT PATHWAY
3 13264 EZETIMIBE//NPC1L1//CHOLESTEROL ABSORPTION INHIBITOR
4 9363 STATINS//STATIN INTOLERANCE//MYOPATHY
5 6021 PRIMARY PREVENTION//CORONARY HEART DISEASE RISK FUNCTIONS//FRAMINGHAM
6 2990 HIGH DENSITY LIPOPROTEIN//HDL//APOLIPOPROTEIN A I
7 406 STATINS//LOW DENSITY LIPOPROTEIN CHOLESTEROL//ATORVASTATIN
8 9225 9P21//CHROMOSOME 9P21//CIRCULATION-CARDIOVASCULAR GENETICS
9 9966 NON HDL CHOLESTEROL//MIKE ROSENBLOOM CARDIOVASC//NON HIGH DENSITY LIPOPROTEIN CHOLESTEROL
10 9107 SREBP//SCAP//STEROL REGULATORY ELEMENT BINDING PROTEIN

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