Class information for:
Level 2: HISTONE DEACETYLASE INHIBITOR//HISTONE DEACETYLASE//HDAC INHIBITOR

Basic class information
Bar chart of Publication_year

Last years might be incomplete

Hierarchy of classes
The table includes all classes above and classes immediately below the current class.


Cluster id Level Cluster label #P
0 4 ONCOLOGY//CELL BIOLOGY//BIOCHEMISTRY & MOLECULAR BIOLOGY 2934640
55 3       CELL BIOLOGY//BIOCHEMISTRY & MOLECULAR BIOLOGY//CHROMATIN 94586
2124 2             HISTONE DEACETYLASE INHIBITOR//HISTONE DEACETYLASE//HDAC INHIBITOR 5445
158 1                   HISTONE DEACETYLASE INHIBITOR//HISTONE DEACETYLASE//HDAC INHIBITOR 4130
17870 1                   MEF2C//MEF2//MEF2D 605
22155 1                   METABOLIC MEMORY//ROGER WILLIAM MED//HOPX 415
25724 1                   PHENYLACETATE//PHENYLBUTYRATE//BLEOMYCIN AMPLIFICATION 295

Terms with highest relevance score


rank Category termType chi_square shrOfCwithTerm shrOfTermInClass termInClass
1 HISTONE DEACETYLASE INHIBITOR authKW 1966369 13% 48% 711
2 HISTONE DEACETYLASE authKW 1195067 11% 34% 616
3 HDAC INHIBITOR authKW 943357 7% 44% 373
4 HDAC authKW 514552 5% 32% 276
5 VORINOSTAT authKW 415695 3% 52% 138
6 SAHA authKW 326813 2% 50% 113
7 PANOBINOSTAT authKW 251225 1% 57% 76
8 SUBEROYLANILIDE HYDROXAMIC ACID authKW 219968 1% 51% 74
9 ROMIDEPSIN authKW 181891 1% 60% 52
10 TRICHOSTATIN A authKW 179360 2% 23% 136

Web of Science journal categories


chi_square_rank Category chi_square shrOfCwithTerm shrOfTermInClass termInClass
1 Oncology 20037 32% 0% 1763
2 Chemistry, Medicinal 10399 13% 0% 734
3 Cell Biology 3464 15% 0% 793
4 Biochemistry & Molecular Biology 3220 23% 0% 1277
5 Pharmacology & Pharmacy 1782 13% 0% 701
6 Hematology 999 5% 0% 267
7 Chemistry, Organic 544 6% 0% 335
8 Medicine, Research & Experimental 517 5% 0% 265
9 Genetics & Heredity 466 5% 0% 288
10 Biophysics 104 3% 0% 149

Address terms


chi_square_rank term chi_square shrOfCwithTerm shrOfTermInClass termInClass
1 EPIGENET HUMAN HLTH DIS 56208 0% 36% 27
2 EPIGEN PROFILING IL 30429 0% 48% 11
3 ROGER WILLIAM MED 28480 0% 62% 8
4 DIPARTIMENTO PATOL GEN 27205 1% 15% 31
5 MOL GENET PREPARAT MOL BIOL 24098 0% 42% 10
6 IL RISK ASSESSMENT INTERVENT STUDIES 23791 0% 34% 12
7 CHEM GENET 19129 0% 13% 26
8 INTER PROGRAM CHEM BIOL 18078 0% 63% 5
9 CCU PEDIAT ONCOL G340 17359 0% 100% 3
10 MOL GENET PRAEPARAT MOL BIOL 17359 0% 100% 3

Journals


chi_square_rank term chi_square shrOfCwithTerm shrOfTermInClass termInClass
1 MOLECULAR CANCER THERAPEUTICS 8686 1% 2% 80
2 CLINICAL CANCER RESEARCH 6096 2% 1% 129
3 BIOORGANIC & MEDICINAL CHEMISTRY LETTERS 5495 3% 1% 160
4 JOURNAL OF MEDICINAL CHEMISTRY 4479 2% 1% 133
5 INVESTIGATIONAL NEW DRUGS 4438 1% 2% 45
6 EPIGENOMICS 3509 0% 3% 18
7 CHEMMEDCHEM 3213 1% 2% 37
8 DRUGS UNDER EXPERIMENTAL AND CLINICAL RESEARCH 2960 1% 2% 31
9 INTERNATIONAL JOURNAL OF ONCOLOGY 2468 1% 1% 66
10 ACS MEDICINAL CHEMISTRY LETTERS 2400 0% 2% 25

Author Key Words


chi_square_rank term chi_square shrOfCwithTerm shrOfTermInClass termInClass LCSH search Wikipedia search
1 HISTONE DEACETYLASE INHIBITOR 1966369 13% 48% 711 Search HISTONE+DEACETYLASE+INHIBITOR Search HISTONE+DEACETYLASE+INHIBITOR
2 HISTONE DEACETYLASE 1195067 11% 34% 616 Search HISTONE+DEACETYLASE Search HISTONE+DEACETYLASE
3 HDAC INHIBITOR 943357 7% 44% 373 Search HDAC+INHIBITOR Search HDAC+INHIBITOR
4 HDAC 514552 5% 32% 276 Search HDAC Search HDAC
5 VORINOSTAT 415695 3% 52% 138 Search VORINOSTAT Search VORINOSTAT
6 SAHA 326813 2% 50% 113 Search SAHA Search SAHA
7 PANOBINOSTAT 251225 1% 57% 76 Search PANOBINOSTAT Search PANOBINOSTAT
8 SUBEROYLANILIDE HYDROXAMIC ACID 219968 1% 51% 74 Search SUBEROYLANILIDE+HYDROXAMIC+ACID Search SUBEROYLANILIDE+HYDROXAMIC+ACID
9 ROMIDEPSIN 181891 1% 60% 52 Search ROMIDEPSIN Search ROMIDEPSIN
10 TRICHOSTATIN A 179360 2% 23% 136 Search TRICHOSTATIN+A Search TRICHOSTATIN+A

Core articles
The table includes core articles in the class. The following variables is taken into account for the relevance score of an article in a cluster c:
(1) Number of references referring to publications in the class.
(2) Share of total number of active references referring to publications in the class.
(3) Age of the article. New articles get higher score than old articles.
(4) Citation rate, normalized to year.

Classes with closest relation at Level 2


rank cluster_id2 link
1 3660 MTA1//ING4//ING1
2 991 EZH2//POLYCOMB//HISTONE DEMETHYLASE
3 384 DNA METHYLATION//EPIGENETICS//METHYLATION
4 2390 SIRTUINS//SIRT1//SIRT3
5 2458 ACUTE PROMYELOCYTIC LEUKEMIA//ARSENIC TRIOXIDE//APL
6 822 NUCLEOSOME//CHROMATIN//SWI SNF
7 2438 EPITHELIAL MESENCHYMAL TRANSITION//EMT//SNAIL
8 3455 BCL6//POKEMON//CITED2
9 2433 KLF4//KRUPPEL LIKE FACTOR//ZINC FINGER
10 2679 NUR77//NURR1//PGC 1 ALPHA

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