Tag Archives: molecular techniques in life science

Why, What, How: Four MTLS students sharing their thesis stories

How important is master project? We all know that

  • It worths one-fourth of academic credits

  • Students are free to choose where to carry out their thesis work

  • 30% students (in Sweden) found their employment directly through master thesis

  • Students acquire essential skills and connections with industry/academia, which eventually build up employability

So, how are our students doing? This weekend, I have the pleasure to chat with four of MTLS students from my class, who are doing their master thesis at different places and working on a diverse scheme of topics! They are:  Leonie (Karolinska Institute in Solna), Mounika (Gabather AB in Huddinge), Dimitri (KTH main campus) and Carolina (Harvard Medical School).

 

1. Leonie von Berlin, Germany

Group: Sten Linarsson (Molecular Biophysics and Biochemistry, Karolinska Institute)

Project: Pipeline development for definition and mapping of cells in human brain with single-cell RNA sequencing (scRNAseq)

The most important lesson I learned is the following: Science takes time. A  LOT OF TIME. If we all accept that four months are barely enough to produce important results and stay relaxed and stay relax, the master project can be a great time of learning and scientific communication. And for having fun!

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Course Review: High-throughput data analysis

The course, BB2491 High-throughput data analysis, is the core of MTLS education at KTH. How does BB2491 differ from traditional biology lectures that we have so far? In this blog I will talk a bit about why, and how we should learn and master high-throughput science!

First, why study high-throughput? It is involved in a myriad of industrial applications, as well as the frontiers of research, to name but a few:

  • Next Generation Sequencing (NGS) is the best illustration of generating and analysing high-throughput data
  • High-throuput compound screening dominates lead discovery for manufacturing of small molecule drug
  • Traditional gene-targeting methods are sufficient for analysis of mendelian diseases, but diseases that involves more complex interplay, requires collecting and analysing “bigger data”

In BB2491, the teaching follows a logical transition from theory, practice to a hand-on project.

THEORY

In biology, high throughput analysis can be split into three parts, namely Genomics, Transcriptomics, and Proteomics. Correspondingly, we have three professors responsible for each part:

        

Lukas Käll                                Lars Arvestad                               Olof Emanuelsson

In contrast to traditional biology lectures, we have no designated text book; alternatively, we have 33 research papers or scientific reviews as mandatory reading materials! It sounds a bit daunting in the beginning, but under the careful guidance of teachers, as well as  fundamental building blocks in previous course (Genomics, Proteomics, Bioinformatics), we are able to dive into the ocean of knowledge!

For example, while Olof introduced the basic concept of RPKM in abundance estimation at the start of the transcriptomics part, it is concluded by four excellent students at the edge of RNA sequencing techniques.

COMPUTER LAB

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Who studies at MTLS? | Statistics of the admitted students

Recently, I received a lot of questions. Many of them look like these: “I study XXX, I want to know if I am eligible to be considered by MTLS? ” or “Are there any current MTLS students who come from YYY, just like me?” In this blog, you are going to find out more about the admitted MTLS students, regarding their demographic profile and academic background, that you CAN’T even get from our official website!

By 2017, there are in total 3 cohorts of students admitted into our programme.

CITIZENSHIP

A purple dot on the map represents the citizenship of one student. The number of students and diversity grow by years.

GENDER

The number of male and female in all three cohorts are roughly equal. Of course, you may notice that gender equality is a fundamental policy in all Swedish universities. In the admission process, no weight will be added/reduced based on gender of the applicant.

ACADEMIC BACKGROUND

It has been told that life science will be an interdisciplinary field; MTLS is no exception. The majors listed in the pie chart are based on the bachelor degree that the students possess:

2016

2017

 

Want to know more about our programme? There are numerous routes:

  1. Our four official websites at KTH, Karolinska Institute, Stockholm University and Science For Life Laboratory
  2. Follow my page MSc Molecular Techniques in Life Science
  3. Subscribe to my blog and get a weekly notification of the newest post!
  4. Contact our student ambassadors: me, Carolina at Karolinska or Javier at KTH!

Updated MTLS Course List

MTLS Molecular Techniques in Life Science has just updated its course list for incoming students in Fall 2018. Make sure to have a look at the list before submitting your application!

Green: new courses

Blue: modified courses (compared with 2016 cohort)

  • Genetics (5.0 hp)
  • Frontiers in Translational Medicine (16.5 hp)
  • Applied Communication (7.0 hp)
  • Applied Programming for Life Science I (1.5 hp)

For detailed description (unofficial and from a personal perspective) of the courses, you may take a look my previous blog about Genetics, Applied Communication and Frontiers in Translational Medicine. (Bear in mind that they may or may not correspond to the updated course content)

  • Bioinformatics (7.0 hp)
  • Methods in Molecular Life Science (7.0 hp)
  • Structure and Dynamics of Biological Membranes (7.0 hp)
  • Comparative Genomics (7.5 hp)
  • Applied Programming for Life Science II (1.5 hp)

Same, you might find Carolina, our best ambassador at Karolinska Institute’s blog very useful for preparing Methods in Molecular Life Science. I also wrote about the Bioinformatics and the predecessor of Structure and Dynamics of Biological Membranes in my previous blog.

Here is Carolina’s blog at KI website: /carolinasavatierdupre/

  • Applied Gene Technology and Large-scale Data Analysis (7.5 hp)
  • Clinical Applications of Biotechnology (6.0 hp)
  • Applied Programming for Life Science III (1.5 hp)

Choose 2 courses out of 3

  • Systems Biology (7.5 hp)
  • Drug Development (7.5 hp)
  • Project in Molecular Life Science (7.5 hp)

  • Master’s Dissertation (30 hp)

Want more information (something unique, something fun) about our programme?

 

MTLS welcomes the third cohort of students

Starting from this September, these 24 talented young people becomes the third “generation” of the family MSc Molecular Techniques in Life Science.

The number of new members rockets from 6 in year 2015, to 19 in year 2016, then this year we have 24!

MTLS Class 2015

MTLS Class  2016

MTLS Class 2017

On Wednesday, my classmates first met and fikad with the third cohort students —— without any exception, they are a amalgamate of ambitious, acquisitive and energetic “scientists in training”.

Here I would like to express thousands of thanks to my classmates Dimitri, who convened all of us with his passion and hospitality. Also, the statistics about their academic background will be posted here later, in favor of the potential applicants of our program.

Finally, my sincerest wish to the new students: the upcoming two years at MTLS will be definitely one of worthiest investment in your life 😉