Aulin Erdtman Young Investigator Lecture
The department of Organic Chemistry at the Royal Institute of Technology, KTH is pleased to announce that the first Aulin Erdtman Young investigator Lectures will take place at KTH on Tuesday September 26 with a Lecture by Prof. Stephen Goldup. The next lecture will be held on October 23 by Prof. Dr. Nuno Maulide (separate invitation). No sign-up required.
Tuesday September 26, 14:00, KTH, Teknikringen 28
Prof. Stephen Goldup
Department of Chemistry, University of Southampton, Southampton, United Kingdom.
Small Functional Rotaxanes
Our group have pioneered the use of “small” macrocycles1 in active template reactions in order to allow the synthesis of small(er), functionalised rotaxanes in excellent yield (Fig 1).2 I will describe some of our recent applications of this methodology to the synthesis of complex homo- and hetero-circuit [n]rotaxanes,3 as well as functional interlocked molecules including sensors and catalysts,4 and discuss our pioneering work on mechanically chiral rotaxanes, a previously hard to access class of chiral molecules.5
1. H. Lahlali, K. Jobe, M. Watkinson and S. M. Goldup, Angew. Chem., Int. Ed., 2011, 50, 4151.
2. J. E. M. Lewis, R. J. Bordoli, M. Denis, C. J. Fletcher, M. Galli, E. A. Neal, E. M. Rochette and S. M. Goldup, Chem. Sci., 2016, 7, 3154.
3. E. A. Neal, S. M. Goldup, Chem. Sci. 2015, 6, 2398; E. A. Neal and S. M. Goldup, Angew. Chem. Int. Ed., 2016,
55, 12488; J. E. M. Lewis, J. Winn, L. Cera and S. M. Goldup, J. Am. Chem. Soc., 2016, 138, 16329.
4. M. Galli, J. E. M. Lewis and S. M. Goldup, Angew. Chem. Int. Ed., 2015, 54, 13545.
5. R. J. Bordoli and S. M. Goldup, J. Am. Chem. Soc., 2014, 136, 4817.
Friday, August 25, 2017, at 13.30
Professor Ben Zhong Tang
Department of Chemistry, Division of Biomedical Engineering, Hong Kong Branch of National Engineering Research Center for Tissue Restoration & Reconstruction, The Hong Kong University of Science and Technology, Clear Water Bay, Kowloon, Hong Kong, China; Email.
"Aggregation-Induced Emission (AIE): A Wonderland Full of Exoticism and Excitement"
Typical chromophores usually suffer from weakening or quenching of light emission caused by aggregation. This notorious photophysical effect is practically harmful because, in real-world applications, luminophores are commonly used in solid state or aqueous media, where chromophores tend to form aggregates. In 2001, we discovered a diametrically opposite phenomenon that some chromophores are non-emissive when dissolved but emissive upon aggregation. We termed this unusual process as aggregation-induced emission (AIE) and identiﬁed the restriction of intramolecular motion (RIM) as the main cause for the AIE eﬀect. In the past 15 years, AIE materials have evolved considerably from molecules to polymers, including the discovery of novel AIEgens with broad emission range covering the visible and near-IR region as well as the exploration of more intriguing applications in such areas as optoelectronic devices, chemo/biosensing, and biological imaging.
Mingdi Yan & Olof Ramström