Aulin Erdtman Young Investigator Lecture

The department of Organic Chemistry at the Royal Institute of Technology, KTH is pleased to announce that the first Aulin Erdtman Young investigator Lectures will take place at KTH on Tuesday September 26 with a Lecture by Prof. Stephen Goldup. The next lecture will be held on October 23 by Prof. Dr. Nuno Maulide (separate invitation). No sign-up required.

Tuesday September 26, 14:00, KTH, Teknikringen 28

Lecture Hall K2, Teknikringen 28, KTH

Prof. Stephen Goldup

Department of Chemistry, University of Southampton, Southampton, United Kingdom.

Biography: Prof. Goldup obtained an MChem degree from the University of Oxford where he began his research career with a Part II project in the group of Sir Prof. Jack Baldwin. He continued his research training with a PhD in natural product synthesis under the supervision of Prof. Tony Barrett before shifting focus to apply his synthetic skills to the realisation of mechanically interlocked non-natural products during post doctoral work with Prof. David Leigh at the University of Edinburgh where in 2007 he was appointed as Fixed Term Lecturer in Organic Chemistry. In 2008 he moved to Queen Mary with the award of a Leverhulme Trust Early Career Fellowship and in October 2009 he was awarded a Royal Society University Research Fellowship. In October 2014 the group moved to the University of Southampton where Steve took up the position of Associate Professor. In August 2017, Steve was promoted to Professor of Chemistry. Research in the Goldup Group focusses on the synthesis of novel mechanically interlocked molecules and their application as sensors, catalysts and materials.

Small Functional Rotaxanes

Our group have pioneered the use of “small” macrocycles1 in active template reactions in order to allow the synthesis of small(er), functionalised rotaxanes in excellent yield (Fig 1).2 I will describe some of our recent applications of this methodology to the synthesis of complex homo- and hetero-circuit [n]rotaxanes,3 as well as functional interlocked molecules including sensors and catalysts,4 and discuss our pioneering work on mechanically chiral rotaxanes, a previously hard to access class of chiral molecules.5 

1. H. Lahlali, K. Jobe, M. Watkinson and S. M. Goldup, Angew. Chem., Int. Ed., 2011, 50, 4151.

2. J. E. M. Lewis, R. J. Bordoli, M. Denis, C. J. Fletcher, M. Galli, E. A. Neal, E. M. Rochette and S. M. Goldup, Chem. Sci., 2016, 7, 3154.

3. E. A. Neal, S. M. Goldup, Chem. Sci. 2015, 6, 2398; E. A. Neal and S. M. Goldup, Angew. Chem. Int. Ed., 2016,

55, 12488; J. E. M. Lewis, J. Winn, L. Cera and S. M. Goldup, J. Am. Chem. Soc., 2016, 138, 16329.

4. M. Galli, J. E. M. Lewis and S. M. Goldup, Angew. Chem. Int. Ed., 2015, 54, 13545.

5. R. J. Bordoli and S. M. Goldup, J. Am. Chem. Soc., 2014, 136, 4817.

Previous seminars

Friday, August 25, 2017, at 13.30

Lecture Hall K2, Teknikringen 28, KTH

Prof. Ben Zhong Tang

Professor Ben Zhong Tang

Department of Chemistry, Division of Biomedical Engineering, Hong Kong Branch of National Engineering Research Center for Tissue Restoration & Reconstruction, The Hong Kong University of Science and Technology, Clear Water Bay, Kowloon, Hong Kong, China; Email.

"Aggregation-Induced Emission (AIE): A Wonderland Full of Exoticism and Excitement"

Typical chromophores usually suffer from weakening or quenching of light emission caused by aggregation. This notorious photophysical effect is practically harmful because, in real-world applications, luminophores are commonly used in solid state or aqueous media, where chromophores tend to form aggregates. In 2001, we discovered a diametrically opposite phenomenon that some chromophores are non-emissive when dissolved but emissive upon aggregation. We termed this unusual process as aggregation-induced emission (AIE) and identified the restriction of intramolecular motion (RIM) as the main cause for the AIE effect. In the past 15 years, AIE materials have evolved considerably from molecules to polymers, including the discovery of novel AIEgens with broad emission range covering the visible and near-IR region as well as the exploration of more intriguing applications in such areas as optoelectronic devices, chemo/biosensing, and biological imaging.


Mingdi Yan & Olof Ramström

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