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Dr. Mathias Uhlén, Professor of Microbiology.
"It's like the periodic table of the body"
On the 20th anniversary of the Human Protein Atlas Project, KTH Professor Mathias Uhlén reflects on the journey of this massive database for understanding human biology and helping researchers develop precision medicine.
A target-seeking professor
He grew up under rather meagre conditions on a farm outside of Strömsund. In upper secondary school, he realised that good grades would be his ticket to another life. Today, Stefan Ståhl is Dean of the School of Biotechnology and Professor in Molecular Biotechnology, where he has been specialising in target proteins for the past 10 years.
First major analysis of Human Protein Atlas published
A research article published today in Science presents the first major analysis based on the Human Protein Atlas, including a detailed picture of the proteins that are linked to cancer, the number of proteins present in the bloodstream, and the targets for all approved drugs on the market.
Protein map is an open resource for health research
A decade after the completion of the blueprint of the human genome, the Human Protein Atlas program on Thursday launched a tissue-based atlas covering the genome's protein complement. Based on 13 million annotated images, an interactive database has been created to show the distribution of proteins in all major tissues and organs in the human body.
Blocking body's endocannabinoids may be effective treatment for liver cancer
The liver's cannabinoid receptors could be targeted to fight liver cancer in some patients, according to a new study that also offers a way to predict what treatments have the best chance of working.
New treatment attacks liver disease and type 2 diabetes
Researchers at KTH Royal Institute of Technology are planning the clinical trial of a new treatment for nonalcoholic fatty liver disease and type 2 diabetes which harnesses liver cells’ own ability to burn accumulated fats.
Study may improve understanding of MS
A group of proteins identified by researchers at KTH Royal Institute of Technology could play a role in helping multiple sclerosis patients get more accurate diagnostics about the severity and progress of their disease.
New hope in fight against muscular dystrophy
Research at KTH Royal Institute of Technology offers hope to those who suffer from Duchenne muscular dystrophy, an incurable, debilitating disease that cuts young lives short.
A map to the human body's 'building blocks'
The human body has hundreds of thousands of cell membrane proteins that are essential for all body functions. “These are amazing miniature machines because they are not just structures”, says Erik Lindahl, Professor of Theoretical and Computational Biophysics at KTH Royal Institute of Technology.
Personalised treatment becoming reality
Researchers at KTH's Science for Life Laboratory are taking the lead in finding key biomarkers that could enable more effective, individualised treatment of serious diseases.