F6L5014 Structure and Funktion of Biological Macromolecules 7.5 credits

Biologiska makromolekylers struktur och funktion

Offering and execution

Course offering missing for current semester as well as for previous and coming semesters

Course information

Content and learning outcomes

Course contents *

The course combines an overview of the structural properties of biological macromolecules with basic knowledge of technologies used to analyze their structure. Specific topics will be used as a starting point to explore molecular approaches to understanding and treatment of human diseases.

Intended learning outcomes *

An introduction to structural biology.

Course Disposition

  • Structural chemistry of biological macromolecules
  • Forces that stabilize biopolymers
  • Structure analysis methods (X-ray diffraction, NMR and electron microscopy)
  • Molecular modeling
  • Structural genomics
  • Computational methods in structural biology
  • Macromolecular structure and disease

Literature and preparations

Specific prerequisites *

Acceptet for doctoral studies at KTH or Karolinska Institutet.

Recommended prerequisites

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Branden, C I & Tooze, J, Introduction to Protein Structure, Garland Publishing 1999, ISBN 0-815-32305-0.
Creighton, T E, Proteins: Structures and Molecular Properties, Freeman 1992, ISBN 0-7167-7030-X.
Handouts from the current literature.

Examination and completion

If the course is discontinued, students may request to be examined during the following two academic years.

Grading scale *

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Examination *

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Based on recommendation from KTH’s coordinator for disabilities, the examiner will decide how to adapt an examination for students with documented disability.

The examiner may apply another examination format when re-examining individual students.

Case report on a specific topic with high relevance to the course content.

Other requirements for final grade *

Quality and content of case report.

Opportunity to complete the requirements via supplementary examination

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Opportunity to raise an approved grade via renewed examination

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Hans Hebert

Ethical approach *

  • All members of a group are responsible for the group's work.
  • In any assessment, every student shall honestly disclose any help received and sources used.
  • In an oral assessment, every student shall be able to present and answer questions about the entire assignment and solution.

Further information

Course web

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Offered by

STH/Structural Biotechnology

Main field of study *

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Education cycle *

Third cycle

Add-on studies

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Caroline Jägerskiöld

Postgraduate course

Postgraduate courses at STH/Structural Biotechnology