Class information for:
Level 1: METFORMIN//ANTIDIABETIC BIGUANIDES//PHENFORMIN

Basic class information
Class id #P Avg. number of
references		 Database coverage
of references
10287 1076 49.6 89%


Bar chart of Publication_year

Last years might be incomplete

Hierarchy of classes
The table includes all classes above and classes immediately below the current class.


Cluster id Level Cluster label #P
0 4 BIOCHEMISTRY & MOLECULAR BIOLOGY//CELL BIOLOGY//ONCOLOGY 4064930
159 3       MENOPAUSE//ISOFLAVONES//TAMOXIFEN 61134
827 2             MAMMOGRAPHIC DENSITY//BREAST DENSITY//METFORMIN 11860
10287 1                   METFORMIN//ANTIDIABETIC BIGUANIDES//PHENFORMIN 1076

Terms with highest relevance score


rank Term termType Chi square Shr. of publ. in
class containing
term		 Class's shr. of
term's tot. occurrences		 #P with
term in
class
1 METFORMIN authKW 2730088 56% 16% 601
2 ANTIDIABETIC BIGUANIDES authKW 113508 0% 100% 4
3 PHENFORMIN authKW 99299 1% 25% 14
4 AMPK authKW 91778 8% 4% 87
5 BIGUANIDES authKW 90868 2% 12% 26
6 ANTI DIABETIC MEDICATIONS authKW 85131 0% 100% 3
7 CARCINOGENESIS ONCOGERONTOL address 66014 1% 21% 11
8 BTIC authKW 56754 0% 100% 2
9 CLIN EPIDEMIOLSAMUEL LUNENFELD address 56754 0% 100% 2
10 METAB CANC GRP address 43354 1% 17% 9

Web of Science journal categories


Rank Term Chi square Shr. of publ. in
class containing
term		 Class's shr. of
term's tot. occurrences		 #P with
term in
class
1 Oncology 11803 54% 0% 580
2 Endocrinology & Metabolism 997 13% 0% 137
3 Cell Biology 751 15% 0% 163
4 Medicine, Research & Experimental 256 7% 0% 74
5 Obstetrics & Gynecology 93 4% 0% 39
6 Pharmacology & Pharmacy 65 7% 0% 78
7 Gastroenterology & Hepatology 59 3% 0% 33
8 Urology & Nephrology 34 2% 0% 26
9 Geriatrics & Gerontology 26 1% 0% 12
10 Hematology 14 2% 0% 21

Address terms


Rank Term Chi square Shr. of publ. in
class containing
term		 Class's shr. of
term's tot. occurrences		 #P with
term in
class
1 CARCINOGENESIS ONCOGERONTOL 66014 1% 21% 11
2 CLIN EPIDEMIOLSAMUEL LUNENFELD 56754 0% 100% 2
3 METAB CANC GRP 43354 1% 17% 9
4 EQUIPE BIOL PATHOL CELLULES MELANOCYTAIRE PIGME 37835 0% 67% 2
5 CELL REPROGRAMMING UNIT 36481 0% 43% 3
6 ONCOENDOCRINOL 33095 1% 17% 7
7 UNIT CLIN 31166 1% 11% 10
8 AMRITU MED SCI 28377 0% 100% 1
9 ANATOLIAN SOC MED ONCOL 28377 0% 100% 1
10 ASAN LIFE SCICOMPARAT PATHOL CORE 28377 0% 100% 1

Journals


Rank Term Chi square Shr. of publ. in
class containing
term		 Class's shr. of
term's tot. occurrences		 #P with
term in
class
1 CANCER PREVENTION RESEARCH 11196 2% 2% 22
2 ONCOTARGET 8271 6% 0% 60
3 AGING-US 3119 1% 1% 10
4 COLD SPRING HARBOR SYMPOSIA ON QUANTITATIVE BIOLOGY SERIES 2752 2% 0% 22
5 DIABETES CARE 1170 2% 0% 22
6 BREAST CANCER RESEARCH AND TREATMENT 1105 2% 0% 17
7 ENDOCRINE-RELATED CANCER 1084 1% 0% 8
8 CELL CYCLE 1070 0% 1% 5
9 ONCOLOGY LETTERS 1000 1% 0% 14
10 PROSTATE CANCER AND PROSTATIC DISEASES 937 1% 1% 6

Author Key Words


Rank Term Chi square Shr. of publ. in
class containing
term		 Class's shr. of
term's tot. occurrences		 #P with
term in
class		 LCSH search Wikipedia search
1 METFORMIN 2730088 56% 16% 601 Search METFORMIN Search METFORMIN
2 ANTIDIABETIC BIGUANIDES 113508 0% 100% 4 Search ANTIDIABETIC+BIGUANIDES Search ANTIDIABETIC+BIGUANIDES
3 PHENFORMIN 99299 1% 25% 14 Search PHENFORMIN Search PHENFORMIN
4 AMPK 91778 8% 4% 87 Search AMPK Search AMPK
5 BIGUANIDES 90868 2% 12% 26 Search BIGUANIDES Search BIGUANIDES
6 ANTI DIABETIC MEDICATIONS 85131 0% 100% 3 Search ANTI+DIABETIC+MEDICATIONS Search ANTI+DIABETIC+MEDICATIONS
7 BTIC 56754 0% 100% 2 Search BTIC Search BTIC
8 SPONTANEOUS CARCINOGENESIS 31920 0% 38% 3 Search SPONTANEOUS+CARCINOGENESIS Search SPONTANEOUS+CARCINOGENESIS
9 ADVANCED REFRACTORY CANCER 28377 0% 100% 1 Search ADVANCED+REFRACTORY+CANCER Search ADVANCED+REFRACTORY+CANCER
10 AGGRESOME PLUS AUTOPHAGOSOME PATHWAY 28377 0% 100% 1 Search AGGRESOME+PLUS+AUTOPHAGOSOME+PATHWAY Search AGGRESOME+PLUS+AUTOPHAGOSOME+PATHWAY

Core articles
The table includes core articles in the class. The following variables is taken into account for the relevance score of an article in a cluster c:
(1) Number of references referring to publications in the class.
(2) Share of total number of active references referring to publications in the class.
(3) Age of the article. New articles get higher score than old articles.
(4) Citation rate, normalized to year.


Rank Reference # ref. in
cl.		 Shr. of ref. in
cl.		 Citations
1 GONG, J , KELEKAR, G , SHEN, J , SHEN, J , KAUR, S , MITA, M , (2016) THE EXPANDING ROLE OF METFORMIN IN CANCER: AN UPDATE ON ANTITUMOR MECHANISMS AND CLINICAL DEVELOPMENT.TARGETED ONCOLOGY. VOL. 11. ISSUE 4. P. 447 -467 127 77% 3
2 CHRISTODOULOU, MI , SCORILAS, A , (2017) METFORMIN AND ANTI-CANCER THERAPEUTICS: HOPES FOR A MORE ENHANCED ARMAMENTARIUM AGAINST HUMAN NEOPLASIAS?.CURRENT MEDICINAL CHEMISTRY. VOL. 24. ISSUE 1. P. 14 -56 137 63% 0
3 ZHANG, HH , GUO, XL , (2016) COMBINATIONAL STRATEGIES OF METFORMIN AND CHEMOTHERAPY IN CANCERS.CANCER CHEMOTHERAPY AND PHARMACOLOGY. VOL. 78. ISSUE 1. P. 13 -26 72 77% 3
4 SUI, XB , XU, YH , WANG, X , HAN, WD , PAN, HM , XIAO, M , (2015) METFORMIN: A NOVEL BUT CONTROVERSIAL DRUG IN CANCER PREVENTION AND TREATMENT.MOLECULAR PHARMACEUTICS. VOL. 12. ISSUE 11. P. 3783 -3791 74 76% 9
5 KORITZINSKY, M , (2015) METFORMIN: A NOVEL BIOLOGICAL MODIFIER OF TUMOR RESPONSE TO RADIATION THERAPY.INTERNATIONAL JOURNAL OF RADIATION ONCOLOGY BIOLOGY PHYSICS. VOL. 93. ISSUE 2. P. 454 -464 70 71% 6
6 GANDINI, S , PUNTONI, M , HECKMAN-STODDARD, BM , DUNN, BK , FORD, L , DECENSI, A , SZABO, E , (2014) METFORMIN AND CANCER RISK AND MORTALITY: A SYSTEMATIC REVIEW AND META-ANALYSIS TAKING INTO ACCOUNT BIASES AND CONFOUNDERS.CANCER PREVENTION RESEARCH. VOL. 7. ISSUE 9. P. 867 -885 61 64% 53
7 MIRANDA, VC , BARROSO-SOUSA, R , GLASBERG, J , RIECHELMANN, RP , (2014) EXPLORING THE ROLE OF METFORMIN IN ANTICANCER TREATMENTS: A SYSTEMATIC REVIEW.DRUGS OF TODAY. VOL. 50. ISSUE 9. P. 623 -640 69 76% 7
8 SUISSA, S , AZOULAY, L , (2012) METFORMIN AND THE RISK OF CANCER TIME-RELATED BIASES IN OBSERVATIONAL STUDIES.DIABETES CARE. VOL. 35. ISSUE 12. P. 2665-2673 45 80% 127
9 RENI, M , DUGNANI, E , CEREDA, S , BELLI, C , BALZANO, G , NICOLETTI, R , LIBERATI, D , PASQUALE, V , SCAVINI, M , MAGGIORA, P , ET AL (2016) (IR)RELEVANCE OF METFORMIN TREATMENT IN PATIENTS WITH METASTATIC PANCREATIC CANCER: AN OPEN-LABEL, RANDOMIZED PHASE II TRIAL.CLINICAL CANCER RESEARCH. VOL. 22. ISSUE 5. P. 1076 -1085 39 83% 8
10 GADDUCCI, A , BIGLIA, N , TANA, R , COSIO, S , GALLO, M , (2016) METFORMIN USE AND GYNECOLOGICAL CANCERS: A NOVEL TREATMENT OPTION EMERGING FROM DRUG REPOSITIONING.CRITICAL REVIEWS IN ONCOLOGY HEMATOLOGY. VOL. 105. ISSUE . P. 73 -83 76 59% 1

Classes with closest relation at Level 1


Rank Class id link
1 6777 COLORECTAL ADENOMA//ADVANCED ADENOMATOUS POLYPS//BREAST ONCODIABETOLOGY
2 8850 METFORMIN//LACTIC ACIDOSIS//BIGUANIDES
3 1917 AMPK//AMP ACTIVATED PROTEIN KINASE//AICAR
4 12558 UNIV INTEGRATED HOSP//PROSTATE CANCER//TOTAL TESTOSTERONE TT
5 4289 3 BROMOPYRUVATE//WARBURG EFFECT//CANCER METABOLISM
6 13989 BLSC//EDISON BIOTECHNOL//AMES DWARF
7 8059 FAMILIAL PANCREATIC CANCER//PANCREATIC CANCER//PANCREATIC NEOPLASMS
8 20061 ALTERNATE DAY FASTING//INTERMITTENT FASTING//LONGEV
9 22786 GLICLAZIDE//ARTIFICIAL CELL MICROENCAPSULATION//BIOTECHNOL DRUG DEV
10 25798 2 DEOXY D GLUCOSE//CELL BIOL R 124//METABOLIC OXIDATIVE STRESS

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